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5. Moderate mixed aortic valve disease -evaluation, treatment and prognosis of patients referred to heart valve center

Author

Lupinek, P, primary, Kotrc, M, additional, Marek, T, additional, Kockova, R, additional, Pecenkova, V, additional, Dorazilova, Z, additional, Blaha, M, additional, Benes, J, additional, Praveckova, A, additional, Kroupova, K, additional, Capkova, V, additional, Podzimkova, M, additional, Kettner, J, additional, and Kautzner, J, additional

Published
2023
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17. Chelators for treatment of iron and copper overload: Shift from low-molecular-weight compounds to polymers

Author

Hruby, M., Santana Martinez, I. I., (0000-0002-2972-2803) Stephan, H., Pouckova, P., Benes, J., Stepanek, P., Hruby, M., Santana Martinez, I. I., (0000-0002-2972-2803) Stephan, H., Pouckova, P., Benes, J., and Stepanek, P.

Abstract

Iron and copper are essential micronutrients needed for the proper function of every cell. However, in excessive amounts these elements are toxic as they may cause oxidative stress resulting in damage of liver and other organs. This may happen due to poisoning, as side effect of thalassemia infusion thera-py or due to hereditary diseases hemochromatosis or Wilson´s disease. The current golden standard of therapy of iron and copper overload is the use of low-molecular-weight chelators of these elements. However, these agents suffer from severe side effects, are often expensive and possess unfavourable pharmacokinetics, which is all limiting useability of such therapy. The emerging concept are poly-mer-supported iron- and copper-chelating therapeutics, either for parenteral or oral use, which show vivid potential to keep therapeutic efficacy of low-molecular-weight agents while avoiding their draw-backs and especially side effects. Critical evaluation of this new perspective polymer approach is the purpose of this review article.

Published
2021

19. The botanical record of archaeobotany Italian network - Brain: A cooperative network, database and website*

Author

Lippi, M, Florenzano, A, Rinaldi, R, Allevato, E, Arobba, D, Bacchetta, G, Bal, M, Mazzanti, M, Benatti, A, Benes, J, Bosi, G, Buonincontri, M, Caramiello, R, Castelletti, L, Castiglioni, E, Celant, A, Clo, E, Costantini, L, Pasquale, G, Di Rita, F, Fiorentino, G, Furlanetto, G, Giardini, M, Grillo, O, Guido, M, Herchenbach, M, Magri, D, Marchesini, M, Maritan, M, Marvelli, S, Masi, A, Miola, A, Montanari, C, Montecchi, M, Motella, S, Nisbet, R, Orru, M, Pena-Chocarro, L, Pepe, C, Perego, R, Rattighieri, E, Ravazzi, C, Rottoli, M, Rowan, E, Sabato, D, Sadori, L, Sarigu, M, Torri, P, Ucchesu, M, Mercuri, A, Lippi M. M., Florenzano A., Rinaldi R., Allevato E., Arobba D., Bacchetta G., Bal M. -C., Mazzanti M. B., Benatti A., Benes J., Bosi G., Buonincontri M., Caramiello R., Castelletti L., Castiglioni E., Celant A., Clo E., Costantini L., Pasquale G. D., Di Rita F., Fiorentino G., Furlanetto G., Giardini M., Grillo O., Guido M., Herchenbach M., Magri D., Marchesini M., Maritan M., Marvelli S., Masi A., Miola A., Montanari C., Montecchi M. C., Motella S., Nisbet R., Orru M., Pena-Chocarro L., Pepe C., Perego R., Rattighieri E., Ravazzi C., Rottoli M., Rowan E., Sabato D., Sadori L., Sarigu M., Torri P., Ucchesu M., Mercuri A. M., Lippi, M, Florenzano, A, Rinaldi, R, Allevato, E, Arobba, D, Bacchetta, G, Bal, M, Mazzanti, M, Benatti, A, Benes, J, Bosi, G, Buonincontri, M, Caramiello, R, Castelletti, L, Castiglioni, E, Celant, A, Clo, E, Costantini, L, Pasquale, G, Di Rita, F, Fiorentino, G, Furlanetto, G, Giardini, M, Grillo, O, Guido, M, Herchenbach, M, Magri, D, Marchesini, M, Maritan, M, Marvelli, S, Masi, A, Miola, A, Montanari, C, Montecchi, M, Motella, S, Nisbet, R, Orru, M, Pena-Chocarro, L, Pepe, C, Perego, R, Rattighieri, E, Ravazzi, C, Rottoli, M, Rowan, E, Sabato, D, Sadori, L, Sarigu, M, Torri, P, Ucchesu, M, Mercuri, A, Lippi M. M., Florenzano A., Rinaldi R., Allevato E., Arobba D., Bacchetta G., Bal M. -C., Mazzanti M. B., Benatti A., Benes J., Bosi G., Buonincontri M., Caramiello R., Castelletti L., Castiglioni E., Celant A., Clo E., Costantini L., Pasquale G. D., Di Rita F., Fiorentino G., Furlanetto G., Giardini M., Grillo O., Guido M., Herchenbach M., Magri D., Marchesini M., Maritan M., Marvelli S., Masi A., Miola A., Montanari C., Montecchi M. C., Motella S., Nisbet R., Orru M., Pena-Chocarro L., Pepe C., Perego R., Rattighieri E., Ravazzi C., Rottoli M., Rowan E., Sabato D., Sadori L., Sarigu M., Torri P., Ucchesu M., and Mercuri A. M.

Abstract

The BRAIN (Botanical Records of Archaeobotany Italian Network) database and network was developed by the cooperation of archaeobotanists working on Italian archaeological sites. Examples of recent research including pollen or other plant remains in analytical and synthetic papers are reported as an exemplar reference list. This paper retraces the main steps of the creation of BRAIN, from the scientific need for the first research cooperation to the website which has a free online access since 2015.

Published
2018

20. The silicon microstrip sensors of the ATLAS semiconductor tracker

Author

Ahmad, A., Albrechtskirchinger, Z., Allport, P.P., Alonso, J., Andricek, L., Apsimon, R.J., Barr, A.J., Bates, R.L., Beck, G.A., Bell, P.J., Belymam, A., Benes, J., Berg, C.M., Bernabeu, J., Bethke, S., Bingefors, N., Bizzell, J.P., Bohm, J., Brenner, R., Brodbeck, T.J., Bruckman De Renstrom, P., Buttar, C.M., Campbell, D., Carpentieri, C., Carter, A.A., Carter, J.R., Charlton, D.G., Casse, G.-L., Chilingarov, A., Cindro, V., Ciocio, A., Civera, J.V., Clark, A.G., Colijn, A.-P., Costa, M.J., Dabrowski, W., Danielsen, K.M., Dawson, I., Demirkoz, B., Dervan, P., Dolezal, Z., Dorholt, O., Duerdoth, I.P., Dwuznik, M., Eckert, S., Ekelöf, T., Eklund, L., Escobar, C., Fasching, D., Feld, L., Ferguson, D.P.S., Ferrere, D., Fortin, R., Foster, J.M., Fox, H., French, R., Fromant, B.P., Fujita, K., Fuster, J., Gadomski, S., Gallop, B.J., García, C., García-Navarro, J.E., Gibson, M.D., Gonzalez, S., Gonzalez-Sevilla, S., Goodrick, M.J., Gornicki, E., Green, C., Greenall, A., Grigson, C., Grillo, A.A., Grosse-Knetter, J., Haber, C., Handa, T., Hara, K., Harper, R.S., Hartjes, F.G., Hashizaki, T., Hauff, D., Hessey, N.P., Hill, J.C., Hollins, T.I., Holt, S., Horazdovsky, T., Hornung, M., Hovland, K.M., Hughes, G., Huse, T., Ikegami, Y., Iwata, Y., Jackson, J.N., Jakobs, K., Jared, R.C., Johansen, L.G., Jones, R.W.L., Jones, T.J., de Jong, P., Joseph, J., Jovanovic, P., Kaplon, J., Kato, Y., Ketterer, C., Kindervaag, I.M., Kodys, P., Koffeman, E., Kohriki, T., Kohout, Z., Kondo, T., Koperny, S., van der Kraaij, E., Kral, V., Kramberger, G., Kudlaty, J., Lacasta, C., Limper, M., Linhart, V., Llosá, G., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Macpherson, A., McMahon, S.J., Macina, D., Magrath, C.A., Malecki, P., Mandić, I., Martí-García, S., Matsuo, T., Meinhardt, J., Mellado, B., Mercer, I.J., Mikestikova, M., Mikuž, M., Miñano, M., Mistry, J., Mitsou, V., Modesto, P., Mohn, B., Molloy, S.D, Moorhead, G., Moraes, A., Morgan, D., Morone, M.C., Morris, J., Moser, H.-G., Moszczynski, A., Muijs, A.J.M., Nagai, K., Nakamura, Y., Nakano, I., Nicholson, R., Niinikoski, T., Nisius, R., Ohsugi, T, O’Shea, V., Oye, O.K., Parzefall, U., Pater, J.R., Pernegger, H., Phillips, P.W., Pospisil, S., Ratoff, P.N., Reznicek, P., Richardson, J.D., Richter, R.H., Robinson, D., Roe, S., Ruggiero, G., Runge, K., Sadrozinski, H.F.W., Sandaker, H., Schieck, J., Seiden, A., Shinma, S., Siegrist, J., Sloan, T., Smith, N.A., Snow, S.W., Solar, M., Solberg, A., Sopko, B., Sospedra, L., Spieler, H., Stanecka, E., Stapnes, S., Stastny, J., Stelzer, F., Stradling, A., Stugu, B., Takashima, R., Tanaka, R., Taylor, G., Terada, S., Thompson, R.J., Titov, M., Tomeda, Y., Tovey, D.R., Turala, M., Turner, P.R., Tyndel, M., Ullán, M., Unno, Y., Vickey, T., Vos, M., Wallny, R., Weilhammer, P., Wells, P.S., Wilson, J.A., Wolter, M., Wormald, M., Wu, S.L., Yamashita, T., Žontar, D., and Zsenei, A.

Published
2007
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23. Beam tests of ATLAS SCT silicon strip detector modules

Author

Campabadal, F., Fleta, C., Key, M., Lozano, M., Martinez, C., Pellegrini, G., Rafi, J.M., Ullan, M., Johansen, L., Pommeresche, B., Stugu, B., Ciocio, A., Fadeyev, V., Gilchriese, M., Haber, C., Siegrist, J., Spieler, H., Vu, C., Bell, P.J., Charlton, D.G., Dowell, J.D., Gallop, B.J., Homer, R.J., Jovanovic, P., Mahout, G., McMahon, T.J., Wilson, J.A., Barr, A.J., Carter, J.R., Fromant, B.P., Goodrick, M.J., Hill, J.C., Lester, C.G., Palmer, M.J., Parker, M.A., Robinson, D., Sabetfakhri, A., Shaw, R.J., Anghinolfi, F., Chesi, E., Chouridou, S., Fortin, R., Grosse-Knetter, J., Gruwe, M., Ferrari, P., Jarron, P., Kaplon, J., Macpherson, A., Niinikoski, T., Pernegger, H., Roe, S., Rudge, A., Ruggiero, G., Wallny, R., Weilhammer, P., Bialas, W., Dabrowski, W., Grybos, P., Koperny, S., Blocki, J., Bruckman, P., Gadomski, S., Godlewski, J., Gornicki, E., Malecki, P., Moszczynski, A., Stanecka, E., Stodulski, M., Szczygiel, R., Turala, M., Wolter, M., Ahmad, A., Benes, J., Carpentieri, C., Feld, L., Ketterer, C., Ludwig, J., Meinhardt, J., Runge, K., Mikulec, B., Mangin-Brinet, M., D’Onofrio, M., Donega, M., Moêd, S., Sfyrla, A., Ferrere, D., Clark, A.G., Perrin, E., Weber, M., Bates, R.L., Cheplakov, A., Saxon, D.H., O’Shea, V., Smith, K.M., Iwata, Y., Ohsugi, T., Kohriki, T., Kondo, T., Terada, S., Ujiie, N., Ikegami, Y., Unno, Y., Takashima, R., Brodbeck, T., Chilingarov, A., Hughes, G., Ratoff, P., Sloan, T., Allport, P.P., Casse, G.-L., Greenall, A., Jackson, J.N., Jones, T.J., King, B.T., Maxfield, S.J., Smith, N.A., Sutcliffe, P., Vossebeld, J., Beck, G.A., Carter, A.A., Lloyd, S.L., Martin, A.J., Morris, J., Morin, J., Nagai, K., Pritchard, T.W., Anderson, B.E., Butterworth, J.M., Fraser, T.J., Jones, T.W., Lane, J.B., Postranecky, M., Warren, M.R.M., Cindro, V., Kramberger, G., Mandić, I., Mikuž, M., Duerdoth, I.P., Freestone, J., Foster, J.M., Ibbotson, M., Loebinger, F.K., Pater, J., Snow, S.W., Thompson, R.J., Atkinson, T.M., Bright, G., Kazi, S., Lindsay, S., Moorhead, G.F., Taylor, G.N., Bachindgagyan, G., Baranova, N., Karmanov, D., Merkine, M., Andricek, L., Bethke, S., Kudlaty, J., Lutz, G., Moser, H.-G., Nisius, R., Richter, R., Schieck, J., Cornelissen, T., Gorfine, G.W., Hartjes, F.G., Hessey, N.P., de Jong, P., Muijs, A.J.M., Peeters, S.J.M., Tomeda, Y., Tanaka, R., Nakano, I., Dorholt, O., Danielsen, K.M., Huse, T., Sandaker, H., Stapnes, S., Bargassaa, P., Reichold, A., Huffman, T., Nickerson, R., Weidberg, A., Doucas, G., Hawes, B., Lau, W., Howell, D., Kundu, N., Wastie, R., Bohm, J., Mikestikova, M., Stastny, J., Broklová, Z., Brož, J., Doležal, Z., Kodyš, P., Kubík, P., Řezníček, P., Vorobel, V., Wilhelm, I., Chren, D., Horazdovsky, T., Linhart, V., Pospisil, S., Sinor, M., Solar, M., Sopko, B., Stekl, I., Ardashev, E.N., Golovnya, S.N., Gorokhov, S.A., Kholodenko, A.G., Rudenko, R.E., Ryadovikov, V.N., Vorobiev, A.P., Adkin, P.J., Apsimon, R.J., Batchelor, L.E., Bizzell, J.P., Booker, P., Davis, V.R., Easton, J.M., Fowler, C., Gibson, M.D., Haywood, S.J., MacWaters, C., Matheson, J.P., Matson, R.M., McMahon, S.J., Morris, F.S., Morrissey, M., Murray, W.J., Phillips, P.W., Tyndel, M., Villani, E.G., Dorfan, D.E., Grillo, A.A., Rosenbaum, F., Sadrozinski, H.F.-W., Seiden, A., Spencer, E., Wilder, M., Booth, P., Buttar, C.M., Dawson, I., Dervan, P., Grigson, C., Harper, R., Moraes, A., Peak, L.S., Varvell, K.E., Chu, Ming-Lee, Hou, Li-Shing, Lee, Shih-Chang, Teng, Ping-Kun, Wan, Changchun, Hara, K., Kato, Y., Kuwano, T., Minagawa, M., Sengoku, H., Bingefors, N., Brenner, R., Ekelöf, T., Eklund, L., Bernabeu, J., Civera, J.V., Costa, M.J., Fuster, J., Garcia, C., Garcia, J.E., Gonzalez-Sevilla, S., Lacasta, C., Llosa, G., Marti-Garcia, S., Modesto, P., Sanchez, J., Sospedra, L., Vos, M., Fasching, D., Gonzalez, S., Jared, R.C., and Charles, E.

Published
2005
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24. Variable radiological lung nodule evaluation leads to divergent management recommendations

Author

Nair, A., Bartlett, E. C., Walsh, S. L. F., Wells, A. U., Navani, N., Hardavella, G., Bhalla, S., Calandriello, L., Devaraj, A., Goo, J. M., Klein, J. S., Macmahon, H., Schaefer-Prokop, C. M., Seo, J. -B., Sverzellati, N., Desai, S. R., Ahlfors, F., Bastos, A., Behr, J., Benes, J., Bozovic, G., Buzan, M. T., Castaner, E., Chaves, M., Choi, Y. W., Dalpiaz, G., David, S., De Jong, P. A., Dournes, G., Eberhard, M., Escuissato, D., Farchione, A., Flors, L., Franchi, P., Frauenfelder, T., Fujimoto, K., Gatti, M., Gavelli, G., Grgic, A., Haine, L., Haramati, L., Hartman, T., Hartmann, I., Hering, J. P., Herpels, V., Herraez, I., Hobbs, S., Hochhegger, B., Hursoy, N., Ip, J., Iyengar, S., Jimenez, J. A., Johnson, K., Kanne, J., Kapur, S., Karaman, C. Z., Karl, R., Kirova, G., Ko, J., Kramer, G., Kul, M., Larici, A. R., Lee, Y., Leifels, L., Ley, S., Machnicki, S., Maidas, P., Mak, S. M., Mariani, F., Meirelles, G., Hoesein, F. A. M., Montet, X., Murchison, J., Nath, H., Nenkina, T., Nganga, E., Nguyen-Kim, T. D. L., Niemann, T., Nunez, C. F. M., Occhipinti, M., Oikonomou, A., Ozawa, Y., Pandher, T., Parkar, A. P., Piciucchi, S., Pinheiro, D., Poerio, A., Polverosi, R., Pope, K., Prosch, H., Pulzato, I., Rampinelli, C., Rodrigues, J., Romanos, O., Romei, C., Roos, J., Rossi, S., Rubtsov, R., Ruggirello, M., Sanchez, M., Santos, M. K., Schubert, M., Senbanjo, T., Silva, C., Silva, M., Snoeckx, A., Sonavane, S., Sriharan, M., Stefanidis, K., Taydas, O., Tomiyama, N., Tran, S., Villanueva, A., Williams, M., and Lung Nodule Evaluation Grp

Subjects
Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Lung Neoplasms, Computed tomography, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, X ray computed, Pulmonary nodule, Radiologists, medicine, 80 and over, Aged, Aged, 80 and over, Female, Humans, Middle Aged, Multiple Pulmonary Nodules, Observer Variation, Practice Guidelines as Topic, Reproducibility of Results, Solitary Pulmonary Nodule, Tomography, X-Ray Computed, Tomography, Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA, Solitary pulmonary nodule, medicine.diagnostic_test, business.industry, Nodule (medicine), medicine.disease, X-Ray Computed, Tomography x ray computed, 030220 oncology & carcinogenesis, Radiological weapon, Human medicine, Radiology, medicine.symptom, business
Abstract

Radiological evaluation of incidentally detected lung nodules on computed tomography (CT) influences management. We assessed international radiological variation in 1) pulmonary nodule characterisation; 2) hypothetical guideline-derived management; and 3) radiologists' management recommendations.107 radiologists from 25 countries evaluated 69 CT-detected nodules, recording: 1) first-choice composition (solid, part-solid or ground-glass, with percentage confidence); 2) morphological features; 3) dimensions; 4) recommended management; and 5) decision-influencing factors. We modelled hypothetical management decisions on the 2005 and updated 2017 Fleischner Society, and both liberal and parsimonious interpretations of the British Thoracic Society 2015 guidelines.Overall agreement for first-choice nodule composition was good (Fleiss' κ=0.65), but poorest for part-solid nodules (weighted κ 0.62, interquartile range 0.50–0.71). Morphological variables, including spiculation (κ=0.35), showed poor-to-moderate agreement (κ=0.23–0.53). Variation in diameter was greatest at key thresholds (5 mm and 6 mm). Agreement for radiologists' recommendations was poor (κ=0.30); 21% disagreed with the majority. Although agreement within the four guideline-modelled management strategies was good (κ=0.63–0.73), 5–10% of radiologists would disagree with majority decisions if they applied guidelines strictly.Agreement was lowest for part-solid nodules, while significant measurement variation exists at important size thresholds. These variations resulted in generally good agreement for guideline-modelled management, but poor agreement for radiologists' actual recommendations.

Published
2018
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37. Fluid challenges in intensive care: the FENICE study: A global inception cohort study

Author

Cecconi, M, Hofer, C, Teboul, J, Pettila, V, Wilkman, E, Molnar, Z, Della Rocca, G, Aldecoa, C, Artigas, A, Jog, S, Sander, M, Spies, C, Lefrant, J, De Backer, D, Silva, E, Zhang, X, Ospina-Tascon, G, Arias, J, Gornik, I, Benes, J, Petersen, A, Zsolt, M, Sprung, C, Koch, M, Guttormsen, A, Tavares, M, Mikaszewska-Sokolewicz, M, Bakker, J, Parke, R, Kirov, M, Wernerman, J, Esen, F, Cannesson, M, Njimi, H, Francois, G, Cueto, G, Hockley, S, Ambekar, H, Laterre, P, Dujardin, M, Damas, P, Deschamps, P, Glorieux, D, Hoste, E, Miribung, M, Devriendt, J, Haentjens, L, Biston, P, Dugernier, T, Bulpa, P, Dive, A, Debaveye, Y, Franck, S, Conde, K, Morsch, R, Ramos, M, Dias, F, Mataloun, S, Mendes, C, Silva, F, Grion, C, Knibel, M, Yang, C, Xiangyu, Z, Cai, G, Ortiz, G, Yepes, D, Londono Arcila, H, Molina, F, Pereira, F, Sanchez-Galvez, H, Benitez, F, Arias Ortiz, J, Gonzalez Rojas, M, Cavric, G, Lukic, E, Zykova, I, Freml, P, Satinsky, I, Suk, P, Novak, I, Balik, M, Szturz, P, Kratochvil, M, Bestle, M, Strange, D, Perner, A, Rasmussen, B, Hauge, J, Meldgaard, M, Toome, V, Kuitunen, A, Varila, S, Hovilehto, S, Pulkkinen, A, Kiviniemi, O, Tallgren, M, Laitio, R, Mongardon, N, Dhonneur, G, Malledant, Y, Lepouse, C, Darmon, M, Mira, J, Chiche, J, Joannes-Boyau, O, Preau, S, Larche, J, Mottard, N, Bengler, C, Argaud, L, Hamzaoui, O, Desebbe, O, Burtin, P, Reignier, J, Durand, M, Guitard, P, Asfar, P, Guillot, M, Boulain, T, Mekontso Dessap, A, Ducrocq, N, Lakhal, K, Gregoire, C, Schmauss, M, Zacharowski, K, Meybohm, P, Treskatsch, S, Bloos, F, van Huelst, S, Baumann, H, Kersten, A, Goldmann, A, Gkiokas, G, Dimoula, A, Kofinas, G, Anthopoulos, G, Pankotai, B, Kopitko, C, Gartner, B, Schaffer, E, Fulesdi, B, Sarkany, A, Samavedam, S, Shah, B, Dixit, S, Toraskar, K, Nandakumar, S, Goila, A, Nayyar, A, Patel, M, Mitra, D, Jagiasi, B, Jakkinaboina, S, Goswami, J, Ghosh, S, Hashemian, M, Mahmoodpoor, A, Breen, D, Benbenishty, J, Kuniavsky, M, Kolpak, O, Castiglione, G, Monti, G, Molin, A, Martucci, G, Panarello, G, Raineri, S, Pota, V, Acquarolo, A, Ploner, F, Lapichino, G, Lombardo, A, Roasio, A, Cardelino, S, Pignataro, A, Oggioni, R, Mangani, V, Parrini, V, Spadaro, S, Volta, C, Alampi, D, Torrente, S, Monastra, L, Marini, F, Mazzini, P, Albanese, D, Riccardi, S, Ruberto, F, Belluomo, A, Silvestri, R, Citerio, G, Brienza, N, Brazzi, L, Protti, A, Bottino, N, David, A, Manzoni, D, Foti, G, Numis, F, Morimatsu, H, Shimizu, K, Munster, L, Rai, V, Buttigieg, M, Pickkers, P, Mijzen, L, Kesecioglu, J, Van Duijn, D, Ormskerk, P, Beck, O, Goodson, J, King, B, Koelle, J, Kantor, S, Gomez, O, Ramos, I, Jedynak, M, Sulkowski, W, Adamik, B, Chruscikowski, M, Wadelek, J, Korzybski, J, Misiewska-Kaczur, A, Piasecka-Twarog, M, Fijaikowska, A, Maciejewski, D, Smiechowicz, K, Milkowska, E, Czerwinska, A, Lukaszewska, A, Wieczorek, A, Czuczwar, M, Czerwiec, A, Tamowicz, B, Branco, V, Estilita, J, Basilio, C, Diogo, C, Toma, R, Bubenek-Turconi, S, Filipescu, D, Popescu, M, Titova, J, Belskiy, V, Smetkin, A, Grigoryev, E, Pugachev, S, Gasenkampf, A, Abouelala, A, Almekhlafi, G, Rupnik, E, Garcia-Delgado, H, Saez Fernandez, A, Celaya Lopez, M, Ramasco, F, Planas, K, Zavala, E, De Nadal, M, Picos, S, Fernandez, S, Munoz, A, Herrera Para, L, Maseda, E, Rovira, A, Monge Garcia, M, Ferrer, R, Sole Violan, J, Garcia Nogales, X, Torrents, E, Ripolles Melchor, J, Tomas Marsilla, J, Araujo Aguilar, P, Aguilar, G, Menor, E, Martinez, M, Leal Micharet, A, Ferri Riera, C, Mosquera, D, Astola, I, Freita-Ramos, S, Garcia Olivares, P, Jimenez Bartolome, M, Fernandez Gonzalez, I, Sanchez-Izquierdo, J, Arribas, P, Gimenez-Esparzavich, C, Anglada, M, Martin, S, Weerakoon, R, Bendjelid, K, Fumeaux, T, Maggiorini, M, Demirkiran, O, Adanir, T, Ergin Ozcan, P, Kelebek Girgin, N, Elahi, N, Kashef, S, Alsabbah, A, Lowe, A, Wise, M, Vizcaychipi, M, Baht, S, Webb, S, Friis, J, Boulanger, C, Gratrix, A, Harvey, D, Ferguson, A, Espie, L, Toth-Tarsoly, P, Lewis, K, Shelley, B, Thuerey, J, Przemyslaw, D, Ranganathan, M, Hormis, A, Spivey, M, Henning, J, Saveker, R, Csabi, P, Bland, M, Barrera Groba, C, Al-Subaie, N, Thomson, R, Hamilton, M, Iannuccelli, F, Roberts, C, Sherwood, N, Kasipandian, V, Silversides, J, Jonas, A, Szakmany, T, Vickers, E, Richards, J, Tham, L, Williams, D, Heenen, S, Hobrok, M, Walden, A, Raj, A, Bauer, P, Kashyap, R, Tolnai, P, Kjelle, B, Andersen, F, Palo, J, Namendys-Silva, S, Cecconi M., Hofer C., Teboul J. -L., Pettila V., Wilkman E., Molnar Z., Della Rocca G., Aldecoa C., Artigas A., Jog S., Sander M., Spies C., Lefrant J. -Y., De Backer D., Silva E., Zhang X., Ospina-Tascon G., Arias J., Gornik I., Benes J., Petersen A., Zsolt M., Sprung C., Koch M., Guttormsen A. B., Tavares M., Mikaszewska-Sokolewicz M., Bakker J., Parke R., Kirov M., Wernerman J., Esen F., Cannesson M., Njimi H., Francois G., Cueto G., Hockley S., Ambekar H., Laterre P. F., Dujardin M. F., Damas P., Deschamps P., Glorieux D., Hoste E., Miribung M., Devriendt J., Haentjens L., Biston P., Dugernier T., Bulpa P., Dive A., Debaveye Y., Franck S., Conde K., Morsch R., Ramos M., Dias F., Mataloun S., Mendes C., Silva F., Grion C., Knibel M., Yang C., Xiangyu Z., Cai G., Ortiz G., Yepes D., Londono Arcila H. F., Molina F., Pereira F., Sanchez-Galvez H. F., Benitez F., Arias Ortiz J., Gonzalez Rojas M., Cavric G., Lukic E., Zykova I., Freml P., Satinsky I., Suk P., Novak I., Balik M., Szturz P., Kratochvil M., Bestle M., Strange D. G., Perner A., Rasmussen B. S., Hauge J., Meldgaard M., Toome V., Kuitunen A., Varila S., Hovilehto S., Pulkkinen A., Kiviniemi O., Tallgren M., Laitio R., Mongardon N., Dhonneur G., Malledant Y., Lepouse C., Darmon M., Mira J. P., Chiche J. D., Joannes-Boyau O., Preau S., Larche J., Mottard N., Bengler C., Argaud L., Hamzaoui O., Desebbe O., Burtin P., Reignier J., Durand M., Guitard P. G., Asfar P., Guillot M., Boulain T., Mekontso Dessap A., Ducrocq N., Lakhal K., Gregoire C., Schmauss M., Zacharowski K., Meybohm P., Treskatsch S., Bloos F., van Huelst S., Baumann H., Kersten A., Goldmann A., Gkiokas G., Dimoula A., Kofinas G., Anthopoulos G., Pankotai B., Kopitko C., Gartner B., Schaffer E., Fulesdi B., Sarkany A., Samavedam S., Shah B., Dixit S., Toraskar K., Nandakumar S., Goila A. K., Nayyar A., Patel M., Mitra D., Jagiasi B., Jakkinaboina S., Goswami J., Ghosh S., Hashemian M., Mahmoodpoor A., Breen D., Benbenishty J., Kuniavsky M., Kolpak O., Castiglione G., Monti G., Molin A., Martucci G., Panarello G., Raineri S. M., Pota V., Acquarolo A., Ploner F., Lapichino G., Lombardo A., Roasio A., Cardelino S., Pignataro A., Oggioni R., Mangani V., Parrini V., Spadaro S., Volta C. A., Alampi D., Torrente S., Monastra L., Marini F., Mazzini P., Albanese D., Riccardi S., Ruberto F., Belluomo A. C., Silvestri R., Citerio G., Brienza N., Brazzi L., Protti A., Bottino N., David A., Manzoni D., Foti G., Numis F., Morimatsu H., Shimizu K., Munster L., Rai V., Buttigieg M., Pickkers P., Mijzen L., Kesecioglu J., Van Duijn D., Ormskerk P., Beck O., Goodson J., King B., Koelle J., Kantor S., Gomez O., Ramos I., Jedynak M., Sulkowski W., Adamik B., Chruscikowski M., Wadelek J., Korzybski J., Misiewska-Kaczur A., Piasecka-Twarog M., Fijaikowska A., Maciejewski D., Smiechowicz K., Milkowska E., Czerwinska A., Lukaszewska A., Wieczorek A., Czuczwar M., Czerwiec A., Tamowicz B., Branco V., Estilita J., Basilio C., Diogo C., Toma R., Bubenek-Turconi S. I., Filipescu D., Popescu M., Titova J., Belskiy V., Smetkin A., Grigoryev E., Pugachev S., Gasenkampf A., Abouelala A., Almekhlafi G., Rupnik E., Garcia-Delgado H., Saez Fernandez A., Celaya Lopez M., Ramasco F., Planas K., Zavala E., De Nadal M., Picos S. A., Fernandez S., Munoz A., Herrera Para L., Maseda E., Rovira A., Monge Garcia M. I., Ferrer R., Sole Violan J., Garcia Nogales X., Torrents E., Ripolles Melchor J., Tomas Marsilla J. I., Araujo Aguilar P., Aguilar G., Menor E. M., Martinez M. C., Leal Micharet A. M., Ferri Riera C., Mosquera D., Astola I., Freita-Ramos S., Garcia Olivares P., Jimenez Bartolome M. B., Fernandez Gonzalez I., Sanchez-Izquierdo J. A., Arribas P., Gimenez-Esparzavich C., Anglada M., Martin S., Weerakoon R. K., Bendjelid K., Fumeaux T., Maggiorini M., Demirkiran O., Adanir T., Ergin Ozcan P., Kelebek Girgin N., Elahi N., Kashef S., Alsabbah A., Lowe A., Wise M., Vizcaychipi M. P., Baht S., Webb S., Friis J., Boulanger C., Gratrix A., Harvey D., Ferguson A., Espie L., Toth-Tarsoly P., Lewis K., Shelley B., Thuerey J., Przemyslaw D., Ranganathan M., Hormis A., Spivey M., Henning J., Saveker R., Csabi P., Bland M., Barrera Groba C., Al-Subaie N., Thomson R., Hamilton M., Iannuccelli F., Roberts C., Sherwood N., Kasipandian V., Silversides J., Jonas A., Szakmany T., Vickers E., Richards J., Tham L., Williams D., Heenen S., Hobrok M., Walden A., Raj A., Bauer P., Kashyap R., Tolnai P., Kjelle B. J., Andersen F. H., Palo J. E., Namendys-Silva S. A., Cecconi, M, Hofer, C, Teboul, J, Pettila, V, Wilkman, E, Molnar, Z, Della Rocca, G, Aldecoa, C, Artigas, A, Jog, S, Sander, M, Spies, C, Lefrant, J, De Backer, D, Silva, E, Zhang, X, Ospina-Tascon, G, Arias, J, Gornik, I, Benes, J, Petersen, A, Zsolt, M, Sprung, C, Koch, M, Guttormsen, A, Tavares, M, Mikaszewska-Sokolewicz, M, Bakker, J, Parke, R, Kirov, M, Wernerman, J, Esen, F, Cannesson, M, Njimi, H, Francois, G, Cueto, G, Hockley, S, Ambekar, H, Laterre, P, Dujardin, M, Damas, P, Deschamps, P, Glorieux, D, Hoste, E, Miribung, M, Devriendt, J, Haentjens, L, Biston, P, Dugernier, T, Bulpa, P, Dive, A, Debaveye, Y, Franck, S, Conde, K, Morsch, R, Ramos, M, Dias, F, Mataloun, S, Mendes, C, Silva, F, Grion, C, Knibel, M, Yang, C, Xiangyu, Z, Cai, G, Ortiz, G, Yepes, D, Londono Arcila, H, Molina, F, Pereira, F, Sanchez-Galvez, H, Benitez, F, Arias Ortiz, J, Gonzalez Rojas, M, Cavric, G, Lukic, E, Zykova, I, Freml, P, Satinsky, I, Suk, P, Novak, I, Balik, M, Szturz, P, Kratochvil, M, Bestle, M, Strange, D, Perner, A, Rasmussen, B, Hauge, J, Meldgaard, M, Toome, V, Kuitunen, A, Varila, S, Hovilehto, S, Pulkkinen, A, Kiviniemi, O, Tallgren, M, Laitio, R, Mongardon, N, Dhonneur, G, Malledant, Y, Lepouse, C, Darmon, M, Mira, J, Chiche, J, Joannes-Boyau, O, Preau, S, Larche, J, Mottard, N, Bengler, C, Argaud, L, Hamzaoui, O, Desebbe, O, Burtin, P, Reignier, J, Durand, M, Guitard, P, Asfar, P, Guillot, M, Boulain, T, Mekontso Dessap, A, Ducrocq, N, Lakhal, K, Gregoire, C, Schmauss, M, Zacharowski, K, Meybohm, P, Treskatsch, S, Bloos, F, van Huelst, S, Baumann, H, Kersten, A, Goldmann, A, Gkiokas, G, Dimoula, A, Kofinas, G, Anthopoulos, G, Pankotai, B, Kopitko, C, Gartner, B, Schaffer, E, Fulesdi, B, Sarkany, A, Samavedam, S, Shah, B, Dixit, S, Toraskar, K, Nandakumar, S, Goila, A, Nayyar, A, Patel, M, Mitra, D, Jagiasi, B, Jakkinaboina, S, Goswami, J, Ghosh, S, Hashemian, M, Mahmoodpoor, A, Breen, D, Benbenishty, J, Kuniavsky, M, Kolpak, O, Castiglione, G, Monti, G, Molin, A, Martucci, G, Panarello, G, Raineri, S, Pota, V, Acquarolo, A, Ploner, F, Lapichino, G, Lombardo, A, Roasio, A, Cardelino, S, Pignataro, A, Oggioni, R, Mangani, V, Parrini, V, Spadaro, S, Volta, C, Alampi, D, Torrente, S, Monastra, L, Marini, F, Mazzini, P, Albanese, D, Riccardi, S, Ruberto, F, Belluomo, A, Silvestri, R, Citerio, G, Brienza, N, Brazzi, L, Protti, A, Bottino, N, David, A, Manzoni, D, Foti, G, Numis, F, Morimatsu, H, Shimizu, K, Munster, L, Rai, V, Buttigieg, M, Pickkers, P, Mijzen, L, Kesecioglu, J, Van Duijn, D, Ormskerk, P, Beck, O, Goodson, J, King, B, Koelle, J, Kantor, S, Gomez, O, Ramos, I, Jedynak, M, Sulkowski, W, Adamik, B, Chruscikowski, M, Wadelek, J, Korzybski, J, Misiewska-Kaczur, A, Piasecka-Twarog, M, Fijaikowska, A, Maciejewski, D, Smiechowicz, K, Milkowska, E, Czerwinska, A, Lukaszewska, A, Wieczorek, A, Czuczwar, M, Czerwiec, A, Tamowicz, B, Branco, V, Estilita, J, Basilio, C, Diogo, C, Toma, R, Bubenek-Turconi, S, Filipescu, D, Popescu, M, Titova, J, Belskiy, V, Smetkin, A, Grigoryev, E, Pugachev, S, Gasenkampf, A, Abouelala, A, Almekhlafi, G, Rupnik, E, Garcia-Delgado, H, Saez Fernandez, A, Celaya Lopez, M, Ramasco, F, Planas, K, Zavala, E, De Nadal, M, Picos, S, Fernandez, S, Munoz, A, Herrera Para, L, Maseda, E, Rovira, A, Monge Garcia, M, Ferrer, R, Sole Violan, J, Garcia Nogales, X, Torrents, E, Ripolles Melchor, J, Tomas Marsilla, J, Araujo Aguilar, P, Aguilar, G, Menor, E, Martinez, M, Leal Micharet, A, Ferri Riera, C, Mosquera, D, Astola, I, Freita-Ramos, S, Garcia Olivares, P, Jimenez Bartolome, M, Fernandez Gonzalez, I, Sanchez-Izquierdo, J, Arribas, P, Gimenez-Esparzavich, C, Anglada, M, Martin, S, Weerakoon, R, Bendjelid, K, Fumeaux, T, Maggiorini, M, Demirkiran, O, Adanir, T, Ergin Ozcan, P, Kelebek Girgin, N, Elahi, N, Kashef, S, Alsabbah, A, Lowe, A, Wise, M, Vizcaychipi, M, Baht, S, Webb, S, Friis, J, Boulanger, C, Gratrix, A, Harvey, D, Ferguson, A, Espie, L, Toth-Tarsoly, P, Lewis, K, Shelley, B, Thuerey, J, Przemyslaw, D, Ranganathan, M, Hormis, A, Spivey, M, Henning, J, Saveker, R, Csabi, P, Bland, M, Barrera Groba, C, Al-Subaie, N, Thomson, R, Hamilton, M, Iannuccelli, F, Roberts, C, Sherwood, N, Kasipandian, V, Silversides, J, Jonas, A, Szakmany, T, Vickers, E, Richards, J, Tham, L, Williams, D, Heenen, S, Hobrok, M, Walden, A, Raj, A, Bauer, P, Kashyap, R, Tolnai, P, Kjelle, B, Andersen, F, Palo, J, Namendys-Silva, S, Cecconi M., Hofer C., Teboul J. -L., Pettila V., Wilkman E., Molnar Z., Della Rocca G., Aldecoa C., Artigas A., Jog S., Sander M., Spies C., Lefrant J. -Y., De Backer D., Silva E., Zhang X., Ospina-Tascon G., Arias J., Gornik I., Benes J., Petersen A., Zsolt M., Sprung C., Koch M., Guttormsen A. B., Tavares M., Mikaszewska-Sokolewicz M., Bakker J., Parke R., Kirov M., Wernerman J., Esen F., Cannesson M., Njimi H., Francois G., Cueto G., Hockley S., Ambekar H., Laterre P. F., Dujardin M. F., Damas P., Deschamps P., Glorieux D., Hoste E., Miribung M., Devriendt J., Haentjens L., Biston P., Dugernier T., Bulpa P., Dive A., Debaveye Y., Franck S., Conde K., Morsch R., Ramos M., Dias F., Mataloun S., Mendes C., Silva F., Grion C., Knibel M., Yang C., Xiangyu Z., Cai G., Ortiz G., Yepes D., Londono Arcila H. F., Molina F., Pereira F., Sanchez-Galvez H. F., Benitez F., Arias Ortiz J., Gonzalez Rojas M., Cavric G., Lukic E., Zykova I., Freml P., Satinsky I., Suk P., Novak I., Balik M., Szturz P., Kratochvil M., Bestle M., Strange D. G., Perner A., Rasmussen B. S., Hauge J., Meldgaard M., Toome V., Kuitunen A., Varila S., Hovilehto S., Pulkkinen A., Kiviniemi O., Tallgren M., Laitio R., Mongardon N., Dhonneur G., Malledant Y., Lepouse C., Darmon M., Mira J. P., Chiche J. D., Joannes-Boyau O., Preau S., Larche J., Mottard N., Bengler C., Argaud L., Hamzaoui O., Desebbe O., Burtin P., Reignier J., Durand M., Guitard P. G., Asfar P., Guillot M., Boulain T., Mekontso Dessap A., Ducrocq N., Lakhal K., Gregoire C., Schmauss M., Zacharowski K., Meybohm P., Treskatsch S., Bloos F., van Huelst S., Baumann H., Kersten A., Goldmann A., Gkiokas G., Dimoula A., Kofinas G., Anthopoulos G., Pankotai B., Kopitko C., Gartner B., Schaffer E., Fulesdi B., Sarkany A., Samavedam S., Shah B., Dixit S., Toraskar K., Nandakumar S., Goila A. K., Nayyar A., Patel M., Mitra D., Jagiasi B., Jakkinaboina S., Goswami J., Ghosh S., Hashemian M., Mahmoodpoor A., Breen D., Benbenishty J., Kuniavsky M., Kolpak O., Castiglione G., Monti G., Molin A., Martucci G., Panarello G., Raineri S. M., Pota V., Acquarolo A., Ploner F., Lapichino G., Lombardo A., Roasio A., Cardelino S., Pignataro A., Oggioni R., Mangani V., Parrini V., Spadaro S., Volta C. A., Alampi D., Torrente S., Monastra L., Marini F., Mazzini P., Albanese D., Riccardi S., Ruberto F., Belluomo A. C., Silvestri R., Citerio G., Brienza N., Brazzi L., Protti A., Bottino N., David A., Manzoni D., Foti G., Numis F., Morimatsu H., Shimizu K., Munster L., Rai V., Buttigieg M., Pickkers P., Mijzen L., Kesecioglu J., Van Duijn D., Ormskerk P., Beck O., Goodson J., King B., Koelle J., Kantor S., Gomez O., Ramos I., Jedynak M., Sulkowski W., Adamik B., Chruscikowski M., Wadelek J., Korzybski J., Misiewska-Kaczur A., Piasecka-Twarog M., Fijaikowska A., Maciejewski D., Smiechowicz K., Milkowska E., Czerwinska A., Lukaszewska A., Wieczorek A., Czuczwar M., Czerwiec A., Tamowicz B., Branco V., Estilita J., Basilio C., Diogo C., Toma R., Bubenek-Turconi S. I., Filipescu D., Popescu M., Titova J., Belskiy V., Smetkin A., Grigoryev E., Pugachev S., Gasenkampf A., Abouelala A., Almekhlafi G., Rupnik E., Garcia-Delgado H., Saez Fernandez A., Celaya Lopez M., Ramasco F., Planas K., Zavala E., De Nadal M., Picos S. A., Fernandez S., Munoz A., Herrera Para L., Maseda E., Rovira A., Monge Garcia M. I., Ferrer R., Sole Violan J., Garcia Nogales X., Torrents E., Ripolles Melchor J., Tomas Marsilla J. I., Araujo Aguilar P., Aguilar G., Menor E. M., Martinez M. C., Leal Micharet A. M., Ferri Riera C., Mosquera D., Astola I., Freita-Ramos S., Garcia Olivares P., Jimenez Bartolome M. B., Fernandez Gonzalez I., Sanchez-Izquierdo J. A., Arribas P., Gimenez-Esparzavich C., Anglada M., Martin S., Weerakoon R. K., Bendjelid K., Fumeaux T., Maggiorini M., Demirkiran O., Adanir T., Ergin Ozcan P., Kelebek Girgin N., Elahi N., Kashef S., Alsabbah A., Lowe A., Wise M., Vizcaychipi M. P., Baht S., Webb S., Friis J., Boulanger C., Gratrix A., Harvey D., Ferguson A., Espie L., Toth-Tarsoly P., Lewis K., Shelley B., Thuerey J., Przemyslaw D., Ranganathan M., Hormis A., Spivey M., Henning J., Saveker R., Csabi P., Bland M., Barrera Groba C., Al-Subaie N., Thomson R., Hamilton M., Iannuccelli F., Roberts C., Sherwood N., Kasipandian V., Silversides J., Jonas A., Szakmany T., Vickers E., Richards J., Tham L., Williams D., Heenen S., Hobrok M., Walden A., Raj A., Bauer P., Kashyap R., Tolnai P., Kjelle B. J., Andersen F. H., Palo J. E., and Namendys-Silva S. A.

Abstract

Background: Fluid challenges (FCs) are one of the most commonly used therapies in critically ill patients and represent the cornerstone of hemodynamic management in intensive care units. There are clear benefits and harms from fluid therapy. Limited data on the indication, type, amount and rate of an FC in critically ill patients exist in the literature. The primary aim was to evaluate how physicians conduct FCs in terms of type, volume, and rate of given fluid; the secondary aim was to evaluate variables used to trigger an FC and to compare the proportion of patients receiving further fluid administration based on the response to the FC. Methods: This was an observational study conducted in ICUs around the world. Each participating unit entered a maximum of 20 patients with one FC. Results: 2213 patients were enrolled and analyzed in the study. The median [interquartile range] amount of fluid given during an FC was 500 ml (500–1000). The median time was 24 min (40–60 min), and the median rate of FC was 1000 [500–1333] ml/h. The main indication for FC was hypotension in 1211 (59 %, CI 57–61 %). In 43 % (CI 41–45 %) of the cases no hemodynamic variable was used. Static markers of preload were used in 785 of 2213 cases (36 %, CI 34–37 %). Dynamic indices of preload responsiveness were used in 483 of 2213 cases (22 %, CI 20–24 %). No safety variable for the FC was used in 72 % (CI 70–74 %) of the cases. There was no statistically significant difference in the proportion of patients who received further fluids after the FC between those with a positive, with an uncertain or with a negatively judged response. Conclusions: The current practice and evaluation of FC in critically ill patients are highly variable. Prediction of fluid responsiveness is not used routinely, safety limits are rarely used, and information from previous failed FCs is not always taken into account.

Published
2015

38. BRAIN. Cooperative network and website

Author

Mercuri, A. M., Allevato, E., Arobba, D., Bacchetta, G., Bal, M. C., Bandini Mazzanti, M., Benes, J., Bosi, G., Buonincontri, M., Caramilello, R., Castelletti, L., Castiglioni, E., Celant, A., Costantini, L., Di Pasquale, G., Fiorentino, G., Florenzano, A., Furlanetto, G., Giardini, M., Grillo, O., Guido, M., Herchenbach, M., Marchesini, M., Mariotti Lippi, M., Maritan, M., Marvelli, S., Masi, A., Miola, A., Montanari, C., Montecchi, M. C., Motella, S., Nisbet, R., Orrù, M., Pena-Chocarro, L., Pepe, C., Perego, R., Rattighieri, E., Ravazzi, C., Rinaldi, R., Rottoli, M., Sabato, D., Sadori, L., Sarigu, M., Torri, P., and Ucchesu, M.

Subjects
Italy, archaeobotany, database
Published
2017

39. Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection

Author

Wilcox, M. H., Gerding, D. N., Poxton, I. R., Kelly, C., Nathan, R., Birch, T., Cornely, O. A., Rahav, G., Bouza, E., Lee, C., Jenkin, G., Jensen, W., Kim, Y. -S., Yoshida, J., Gabryelski, L., Pedley, A., Eves, K., Tipping, R., Guris, D., Kartsonis, N., Playford G, Dorr M. -B., Mcgechie, D, Iredell, J, Allworth, A, Cheng, A, Choi, Nj, Thalhammer, F, Maieron, A, Wenisch, C, Meyer, B, Jacobs, F, Delmee, M, Peetermans, W, Giot, Jb, Munhoz, Al, Kallas, Eg, Ladeira, Jp, Bernstein, Cn, Grimard, D, Mcgeer, A, Poirier, A, Valiquette, L, Miller, M, Oughton, M, Trottier, S, Dolce, P, Smyth, D, Gambra, P, Palma, S, Rojas, L, Northland, R, Arellano, Mc, Perez, J, Barreto, Mf, Gomez, Jm, Ramirez, I, Correa, A, Onate, J, Rohacova, H, Stastnik, M, Zjevikova, A, Blazek, J, Kumpel, P, Petersen, Am, Gluud, Ll, Staugaard, Hm, Tvede, M, Glerup, H, Madsen, Sm, Helms, M, Naumann, R, Karthaus, M, Reinshagen, M, Raz, R, Giladi, M, Chowers, M, Bishara, J, Quirino, T, Castelli, F, Bassetti, M, Rizzardini, G, Vismara, E, Puoti, M, Viale, P, Menichetti, F, Cauda, R, Bonfanti, P, Franzetti, F, Gori, A, Minoli, L, Noriega, Er, Mills, Gd, Ritchie, S, Burns, A, Pithie, A, dos Santos RM, Aldomiro, F, Fernando, Pb, Rola, J, Reis, E, Van Zyl JH, Aboo, N, Richards, G, Hernandez, Mj, de Medrano VA, Prunonosa, Lm, Gonzalez, Jl, Reinoso, Jc, Martinez, Ar, Cisneros, Jd, Banos, Jr, Sheridan, R, Minton, J, Williams, J, Stanley, P, Guleri, A, Llewelyn, M, Todd, N, Barlow, G, Bacon, Ae, Baird, Im, Baxter, R, Zenilman, Jm, Beshay, M, Betts, Rf, Brettholz, Em, Buitrago, Mi, Carlson, Rw, Cook, Pp, Dupont, Hl, Foley, C, Freilich, B, Giron, Ja, Golan, Y, Green, S, Hall, Mc, Johnson, Dj, Jones, Rk, Graham, Dr, Kazimir, M, Keating, M, Brumble, Lm, Kumar, Pn, Liappis, Ap, Libke, R, Mehra, Pk, Overcash, Sj, Mullane, Km, Nguyen, Mh, Patel, Mc, Powers, Ck, Pullman, J, Keegan, J, Nepal, S, English, G, Ricci, Rl, Risi, Gf, Rodriguez, M, Schmitt, Cm, Sims, Md, Kamepalli, R, Tural, A, Vazquez, Ja, Alangaden, Gj, Weavind, Lm, Young, Ma, Chen, St, Liu, E, Nguyen, Hh, Alfonso, Tb, Muse, Dd, Orenstein, R, Yacyshyn, B, Gebhard, Re, Dinges, W, Bolton, M, Rubin, M, Kuemmerle, Jf, Limaye, Ap, Friedenberg, Ka, Hiemenz, Jw, Quadri, A, Martinez, Jv, Barcan, La, Cordova, E, Mykietiuk, A, Losso, M, Fedorak, Rn, Steiner, T, Gerson, M, Weiss, K, Dlouhy, P, Vitous, A, Benes, J, Husa, P, Knizek, P, Anttila, Vj, Broas, M, Camou, F, Postil, D, Launay, O, Corroyer-Simovic, B, Meynard, Jl, Schneider, S, Molina, Jm, Neau, D, Zalcman, G, Boutoille, D, Ostermann, H, Heinz, W, Reuter, S, Oren, I, Schiff, E, Umemoto, T, Masubuchi, T, Mukawa, K, Yasuda, K, Imokawa, S, Fukuda, K, Ohta, H, Harada, N, Fujii, S, Tamaki, S, Yasui, S, Furukawa, K, Takahashi, M, Uraoka, T, Watanabe, M, Ikehara, Y, Kodaira, M, Komatsu, H, Higashi, K, Taguchi, F, Ura, N, Serizawa, Y, Fukuchi, T, Ashikawa, T, Shabana, M, Okubo, M, Matsumoto, M, Kurihara, A, Miyasaka, E, Shimizu, M, Tominaga, H, Kubota, T, Kashiwazaki, M, Masuda, Y, Terasaki, S, Okafuji, H, Mieno, H, Urabe, T, Okamoto, E, Kajimura, M, Yamagishi, Y, Rydzewska, G, Mach, T, Ciechanowski, K, Podlasin, R, Tomasiewicz, K, Janczewska-Kazek, E, Czarnobilski, K, Halota, W, Gryglewska, B, Plesniak, R, Dabrowiecki, P, Lipowski, D, Simanenkov, V, Shcheglova, L, Uspenskiy, Y, Cheganov, A, Han, Ds, Kim, Js, Hong, Sp, Kim, Ti, Jang, Bi, Byeon, Js, Kim, E, Kim, Mj, Lee, J, Pai, H, Cheong, Hj, Lee, S, Loyarte, Ja, Gonzalez, Jc, Santiago, Eb, Lopez, Jr, Baranda, Jm, Viladomiu, As, Calbo, E, Lannergard, A, Falt, J, Gardlund, B, Andersson, Lm, Fraenkel, Cj, Rombo, L, Widmer, A, Chen, Yc, Sheng, Wh, Wang, Fd, Wang, Nc, Lee, Ch, Chen, Yh, Chuang, Yc, Unal, S, Ozaras, R, Esen, S, Ural, O, Ayaz, C, Sakarya, S, Celebi, A, Mistik, R, Bedimo, R, Bressler, A, Mckinley, Mj, Quirk, D, Talansky, Al, Agronin, Me, Akhrass, Fa, Ali, M, Alrabaa, Sf, Assi, Ma, Calfee, Dp, Carson, P, Mariani, Pg, Guerrero, D, Dubberke, Er, Hardi, R, Hazan-Steinberg, S, Itani, Km, Jauregui-Peredo, El, Kasabji, A, Hameed, M, Murillo, A, Odio, Aj, Shah, P, Braun, Ti, Slim, J, Sloan, L, Srinivasan, S, Tan, Mj, Clough, La, Herr, D, Miller, Lg, Dorfmeister, J, Khan, O, and Melik-Abrahamian, F.

Subjects
0301 basic medicine, Male, Adolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Antibodies, Monoclonal, Antibodies, Neutralizing, Clostridium Infections, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Infusions, Intravenous, Intention to Treat Analysis, Kaplan-Meier Estimate, Middle Aged, Secondary Prevention, Young Adult, Clostridium difficile, Clinical Trial, Phase III, Antibiotics, 0302 clinical medicine, Monoclonal, 80 and over, 030212 general & internal medicine, Medicine (all), Neutralizing, education.field_of_study, Research Support, Non-U.S. Gov't, General Medicine, Multicenter Study, Randomized Controlled Trial, Combination, Broadly Neutralizing Antibodies, Intravenous, medicine.medical_specialty, Infusions, medicine.drug_class, 030106 microbiology, Population, Placebo, Antibodies, 03 medical and health sciences, Pharmacotherapy, Drug Therapy, Internal medicine, Journal Article, medicine, education, Intention-to-treat analysis, Clostridioides difficile, business.industry, Interim analysis, Surgery, Bezlotoxumab, business
Abstract

BACKGROUND: Clostridium difficile is the most common cause of infectious diarrhea in hospitalized patients. Recurrences are common after antibiotic therapy. Actoxumab and bezlotoxumab are human monoclonal antibodies against C. difficile toxins A and B, respectively.METHODS: We conducted two double-blind, randomized, placebo-controlled, phase 3 trials, MODIFY I and MODIFY II, involving 2655 adults receiving oral standard-of-care antibiotics for primary or recurrent C. difficile infection. Participants received an infusion of bezlotoxumab (10 mg per kilogram of body weight), actoxumab plus bezlotoxumab (10 mg per kilogram each), or placebo; actoxumab alone (10 mg per kilogram) was given in MODIFY I but discontinued after a planned interim analysis. The primary end point was recurrent infection (new episode after initial clinical cure) within 12 weeks after infusion in the modified intention-to-treat population.RESULTS: In both trials, the rate of recurrent C. difficile infection was significantly lower with bezlotoxumab alone than with placebo (MODIFY I: 17% [67 of 386] vs. 28% [109 of 395]; adjusted difference, -10.1 percentage points; 95% confidence interval [CI], -15.9 to -4.3; PCONCLUSIONS: Among participants receiving antibiotic treatment for primary or recurrent C. difficile infection, bezlotoxumab was associated with a substantially lower rate of recurrent infection than placebo and had a safety profile similar to that of placebo. The addition of actoxumab did not improve efficacy. (Funded by Merck; MODIFY I and MODIFY II ClinicalTrials.gov numbers, NCT01241552 and NCT01513239 .).

Published
2017
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40. Archaeobotanical evidence of fig (Ficus carica L.) in Europe on the axis of South - north gradient. Preliminary information about Papaver Centre Research Project

Author

Benes J., Karg S., Kodydkova K., Mercuri A. M., Bosi G., Pokorna A., Preusz M., Rosch M., Fischer E., Arobba D., Bandini Mazzanti M., Buonicorti M., Caramiello R., Carra M. L., Castiglioni E., Celant A., Costantini L., Marchesini M., Mariotti Lippi M., Maritan M., Miolla S., Masi A., Miola A., Mori Secci M., Nisbet R., Pena Chocarro L., Pepe C., Rinaldi R., Rottoli M., Sabato D., Sadori L., Ucchesu M., FIORENTINO, Girolamo, Bernardova A., Kodydkova K., Benes, J., Karg, S., Kodydkova, K., Mercuri, A. M., Bosi, G., Pokorna, A., Preusz, M., Rosch, M., Fischer, E., Arobba, D., Bandini Mazzanti, M., Buonicorti, M., Caramiello, R., Carra, M. L., Castiglioni, E., Celant, A., Costantini, L., Fiorentino, Girolamo, Marchesini, M., Mariotti Lippi, M., Maritan, M., Miolla, S., Masi, A., Miola, A., Mori Secci, M., Nisbet, R., Pena Chocarro, L., Pepe, C., Rinaldi, R., Rottoli, M., Sabato, D., Sadori, L., and Ucchesu, M.

Published
2015

44. Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Association of deletion allele of insertion/deletion polymorphism in alpha 2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus295Association of G1359A polymorphism of the endocannabinoid type 1 receptor (CNR1) with coronary artery disease (CAD) with type 2 diabetes mellitusCell growth, differentiation and stem cells - Vascular298Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus299Mesenchymal stromal-like cells (MLCs) derived from induced pluripotent stem (iPS) cells: a promising therapeutic option to promote neovascularization300Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease301Proinflammatory cytokine secretion and epigenetic modification in endothelial cells treated LPS-GinfivalisCell death and apoptosis - Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - Vascular320Effect of gastrin-releasing peptide (GRP) on vascular inflammationSignal transduction - Heart323A new synthetic peptide regulates hypertrophy in vitro through means of the inhibition of nfkb324Inducible fibroblast-specific knockout of p38 alpha map kinase is cardioprotective in a mouse model of isoproterenol-induced cardiac hypertrophy325Regulation of beta-adrenoceptor-evoked inotropic responses by inhibitory G protein, adenylyl cyclase isoforms 5 and 6 and phosphodiesterases326Binding to RGS3 and stimulation of M2 muscarinic acetylcholine receptors modulates the substrate specificity of p190RhoGAP in cardiac myocytes327Cardiac regulation of post-translational modifications, parylation and deacetylation in LMNA dilated cardiomyopathy mouse model328Beta-adrenergic regulation of the b56delta/pp2a holoenzyme in cardiac myocytes through b56delta phosphorylation at serine 573Nitric oxide and reactive oxygen species - Vascular331Oxidative stress-induced miR-200c disrupts the regulatory loop among SIRT1, FOXO1 and eNOS332Antioxidant therapy prevents oxidative stress-induced endothelial dysfunction and Enhances Wound Healing333Morphological and biochemical characterization of red blood cell in coronary artery diseaseCytoskeleton and mechanotransduction - Heart336Novel myosin activator, JSH compounds, increased myocardial contractility without chronotropic effect in ratsExtracellular matrix and fibrosis - Vascular339Ablation of Toll-like receptor 9 causes cardiac rupture after myocardial infarction by attenuating proliferation and differentiation of cardiac fibroblasts340Altered vascular remodeling in the mouse hind limb ischemia model in Factor VII activating protease (FSAP) deficiencyVasculogenesis, angiogenesis and arteriogenesis343Pro-angiogenic effects of proly-hydroxylase inhibitors and their potential for use in a novel strategy of therapeutic angiogenesis for coronary total occlusion344Nrf2 drives angiogenesis in transcription-independent manner: new function of the master regulator of oxidative stress response345Angiogenic gene therapy, despite efficient vascular growth, is not able to improve muscle function in normoxic or chronically ischemic rabbit hindlimbs -role of capillary arterialization and shunting346Effect of PAR-1 inhibition on collateral vessel growth in the murine hind limb model347Quaking is a key regulator of endothelial cell differentiation, neovascularization and angiogenesis348"Emerging angiogenesis" in the chick chorioallantoic membrane (CAM). An in vivo study349Exosomes from cardiomyocyte progenitor cells and mesenchymal stem cells stimulate angiogenesis in vitro and in vivo via EMMPRINEndothelium352Reciprocal regulation of GRK2 and bradykinin receptor stimulation modulate Ca2+ intracellular level in endothelial cells353The roles of bone morphogenetic proteins 9 and 10 in endothelial inflammation and atherosclerosis354The contribution of GPR55 to the L-alpha-lysophosphatidylinositol-induced vasorelaxation in isolated human pulmonary arteries355The endothelial protective ACE inhibitor Zofenoprilat exerts anti-inflammatory activities through H2S production356A new class of glycomimetic drugs to prevent free fatty acid-induced endothelial dysfunction357Endothelial progenitor cells to apoptotic endothelial cell-derived microparticles ration differentiatesas preserved from reduced ejection fractionheart failure358Proosteogenic genes are activated in endothelial cells of patients with thoracic aortic aneurysm359Endothelin ETB receptors mediate relaxing responses to insulin in pericardial resistance arteries from patients with cardiovascular disease (CVD)Smooth muscle and pericytes362CX3CR1 positive myeloid cells regulate vascular smooth muscle tone by inducing calcium oscillations via activation of IP3 receptors363A novel function of PI3Kg on cAMP regulation, role in arterial wall hyperplasia through modulation of smooth muscle cells proliferation364NRP1 and NRP2 play important roles in the development of neointimal hyperplasia in vivo365Azithromycin induces autophagy in aortic smooth muscle cellsCoagulation, thrombosis and platelets368The real time in vivo evaluation of platelet-dependent aldosterone prothrombotic action in mice369Development of a method for in vivo detection of active thrombi in mice370The antiplatelet effects of structural analogs of the taurine chloramine371The influence of heparin anticoagulant drugs on functional state of human platelets372Regulation of platelet aggregation and adenosine diphosphate release by d dimer in acute coronary syndrome (in vitro study)Oxygen sensing, ischaemia and reperfusion375Sirtuin 5 mediates brain injury in a mouse model of cerebral ischemia-reperfusion376Abscisic acid: a new player in cardiomyocyte protection from ischaemia?377Protective effects of ultramicronized palmitoylethanolamide (PEA-um) in myocardial ischaemia and reperfusion injury in vivo378Identification of stem cell-derived cardiomyocytes using cardiac specific markers and additional testing of these cells in simulated ischemia/reperfusion system379Single-dose intravenous metformin treatment could afford significant protection of the injured rat kidney in an experimental model of ischemia-reperfusion380Cardiotoxicity of long acting muscarinic receptor antagonists used for chronic obstructive pulmonary disease381Dependence antioxidant potential on the concentration of amino acids382The impact of ischemia-reperfusion on physiological parameters,apoptosis and ultrastructure of rabbit myocardium with experimental aterosclerosisMitochondria and energetics385MicroRNA-1 dependent regulation of mitochondrial calcium uniporter (MCU) in normal and hypertrophied hearts386Mitochondrial homeostasis and cardioprotection: common targets for desmin and aB-crystallin387Overexpression of mitofusin-2 (Mfn2) and associated mitochondrial dysfunction in the diabetic heart388NO-dependent prevention of permeability transition pore (MPTP) opening by H2S and its regulation of Ca2+ accumulation in rat heart mitochondria389G protein coupled receptor kinase 2 (GRK2) is fundamental in recovering mitochondrial morphology and function after exposure to ionizing radiation (IR)Gender issues392Sex differences in pulmonary vascular control; focus on the nitric oxide pathwayAging395Heart failure with preserved ejection fraction develops when feeding western diet to senescence-accelerated mice396Cardiovascular markers as predictors of cognitive decline in elderly hypertensive patients397Changes in connexin43 in old rats with volume overload chronic heart failureGenetics and epigenetics400Calcium content in the aortic valve is associated with 1G>2G matrix metalloproteinase 1 polymorphism401Neuropeptide receptor gene s (NPSR1) polymorphism and sleep disturbances402Endothelin-1 gene Lys198Asn polymorphism in men with essential hypertension complicated and uncomplicated with chronic heart failure403Association of common polymorphisms of the lipoprotein lipase and pon1 genes with the metabolic syndrome in a sample of community participantsGenomics, proteomics, metabolomics, lipidomics and glycomics405Gene expression quantification using multiplexed color-coded probe pairs to determine RNA content in sporadic cardiac myxoma406Large-scale phosphorylation study of the type 2 diabetic heart subjected to ischemia / reperfusion injury407Transcriptome-based identification of new anti-inflammatory properties of the olive oil hydroxytyrosol in vascular endothelial cell under basal and proinflammatory conditions408Gene polymorphisms combinations and risk of myocardial infarctionComputer modelling, bioinformatics and big data411Comparison of the repolarization reserve in three state-of-the-art models of the human ventricular action potentialMetabolism, diabetes mellitus and obesity414Endothelial monocyte-activating polypeptide-II improves heart function in type -I Diabetes mellitus415Admission glucose level is independent predictor of impaired left ventricular function in patients with acute myocardial infarction: a two dimensional speckle-tracking echocardiography study416Association between biochemical markers of lipid profile and inflammatory reaction and stiffness of the vascular wall in hypertensive patients with abdominal obesity417Multiple common co-morbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress and myocardial stiffening418Investigating the cardiovascular effects of antiretroviral drugs in a lean and high fat/sucrose diet rat model of obesity419Statins in the treatment of non-alcoholic steatohepatitis (NASH). Our experience from a 2-year prospective study in Constanta County, Romania420Epicardial adipose tissue as a predictor of cardiovascular outcome in patients with ACS undergoing PCI?Arterial and pulmonary hypertension423Dependence between heart rhythm disorers and ID polymorphism of ACE gene in hypertensive patients424Molecular mechanisms underlying the beneficial effects of Urocortin 2 in pulmonary arterial hypertension425Inhibition of TGf-b axis and action of renin-angiotensin system in human ascending aorta aneurysms426Early signs of microcirculation and macrocirculation abnormalities in prehypertension427Vascular smooth muscle cell-expressed Tie-2 controls vascular tone428Cardiac and vascular remodelling in the development of chronic thrombo-embolic pulmonary hypertension in a novel swine modelBiomarkers431Arrhythmogenic cardiomyopathy: a new, non invasive biomarker432Can circulating microRNAs distinguish type 1 and type 2 myocardial infarction?433Design of a high-throughput multiplex proteomics assay to identify left ventricular diastolic dysfunction in diabetes434Monocyte-derived and P-selectin-carrying microparticles are differently modified by a low fat diet in patients with cardiovascular risk factors who will and who will not develop a cardiovascular event435Red blood cell distribution width assessment by polychromatic interference microscopy of thin films in chronic heart failure436Invasive and noninvasive evaluation of quality of radiofrequency-induced cardiac denervation in patients with atrial fibrillation437The effect of therapeutic hypothermia on the level of brain derived neurotrophic factor (BDNF) in sera following cardiopulmonary resustitation438Novel biomarkers to predict outcome in patients with heart failure and severe aortic stenosis439Biological factors linking depression and anxiety to cardiovascular disease440Troponins and myoglobin dynamic at coronary arteries graftingInvasive, non-invasive and molecular imaging443Diet composition effects on the genetic typing of the mouse ob mutation: a micro-ultrasound characterization of cardiac function, macro and micro circulation and liver steatosis444Characterization of pig coronary and rabbit aortic lesions using IV-OCT quantitative analysis: correlations with histologyGene therapy and cell therapy447Enhancing the survival and angiogenic potential of mouse atrial mesenchymal cells448VCAM-1 expression in experimental myocardial infarction and its relation to bone marrow-derived mononuclear cell retentionTissue engineering451Advanced multi layered scaffold that increases the maturity of stem cell-derived human cardiomyocytes452Response of engineered heart tissue to simulated ischemia/reperfusion in the presence of acute hyperglycemic conditions453Serum albumin hydrogels prevent de-differentiation of neonatal cardiomyocytes454A novel paintbrush technique for transfer of low viscosity ultraviolet light curable cyan methacrylate on saline immersed in-vitro sheep heart

Author

Garcia-Martinez, V, primary, Lopez Sanchez, C, primary, Hamed, W, primary, Hsu, JH, primary, Ferrer-Lorente, R, primary, Alshamrani, Maryam, primary, Pizzicannella, J, primary, Vindis, C, primary, Badi, I, primary, Korte, L, primary, Voellenkle, C, primary, Niculescu, L S, primary, Massaro, M, primary, Babaeva, AR, primary, Da Silva, F, primary, Woudstra, L, primary, Berezin, A, primary, Bae, MK, primary, Del Giudice, C, primary, Bageghni, S A, primary, Krobert, K, primary, Levay, M, primary, Vignier, N, primary, Ranieri, A, primary, Magenta, A, primary, Orlandi, A, primary, Porro, B, primary, Jeon, E-S, primary, Omori, Y, primary, Herold, J, primary, Barnett, G A, primary, Grochot-Przeczek, A, primary, Korpisalo, P, primary, Deffge, C, primary, Margariti, A, primary, Rong, W, primary, Maring, JA, primary, Gambardella, J, primary, Mitrofan, CG, primary, Karpinska, O, primary, Morbidelli, L, primary, Wilkinson, FL, primary, Kostina, AS, primary, De Mey, J G R, primary, Kumar, A, primary, Lupieri, A, primary, Pellet-Many, C, primary, Stamatiou, R, primary, Gromotowicz, A, primary, Dickhout, A, primary, Murina, M, primary, Roka-Moiia, YM, primary, Malinova, L, primary, Diaz-Canestro, C, primary, Vigliarolo, T, primary, Cuzzocrea, S, primary, Szantai, A, primary, Medic, B, primary, Cassambai, S, primary, Korda, A, primary, Revnic, C R, primary, Borile, G, primary, Diokmetzidou, A, primary, Murfitt, L, primary, Budko, A, primary, Fiordelisi, A, primary, De Wijs-Meijler, DPM, primary, Gevaert, AB, primary, Noriega De La Colina, A, primary, Benes, J, primary, Guillermo Solache Berrocal, GSB, primary, Gafarov, V, primary, Zhebel, VM, primary, Prakaschandra, R, primary, Stepien, E L, primary, Smith, LE, primary, Carluccio, MA, primary, Timasheva, Y, primary, Paci, M, primary, Dorofeyeva, N A, primary, Chimed, CH, primary, Petelina, TI, primary, Sorop, O, primary, Genis, A, primary, Parepa, I R, primary, Tscharre, M, primary, Krestjyaninov, MV, primary, Maia-Rocha, C, primary, Borges, L, primary, Sasonko, M L, primary, Kapel, SS, primary, Stam, K, primary, Sommariva, E, primary, Stojkovic, S, primary, O'reilly, J, primary, Chiva-Blanch, G, primary, Evtushenko, A, primary, Skopal, J, primary, Sunderland, N, primary, Gegenava, T, primary, Charnaia, MA, primary, Di Lascio, N, primary, Tarvainen, SJ, primary, Malandraki-Miller, S, primary, Uitterdijk, A, primary, Benzoni, P, primary, Ruivo, E, primary, Humphrey, E J, primary, Arokiaraj, MC, primary, Franco, D, additional, Garcia-Lopez, V, additional, Aranega, A, additional, Lopez-Sanchez, C, additional, Garcia-Martinez, V, additional, Tayel, S, additional, Khader, H, additional, El-Helbawy, N, additional, Alrefai, A, additional, El-Barbary, H, additional, Wu, JR, additional, Dai, ZK, additional, Yeh, JL, additional, Sanjurjo-Rodriguez, C, additional, Richaud-Patin, Y, additional, Blanco, FJ, additional, Badimon, L, additional, Raya, A, additional, Cahill, Paul A, additional, Diomede, F, additional, Merciaro, I, additional, Trubiani, O, additional, Nahapetyan, H, additional, Swiader, A, additional, Faccini, J, additional, Boya, P, additional, Elbaz, M, additional, Zeni, F, additional, Burba, I, additional, Bertolotti, M, additional, Capogrossi, MC, additional, Pompilio, G, additional, Raucci, A, additional, Widmer-Teske, R, additional, Dutzmann, J, additional, Bauersachs, J, additional, Donde, K, additional, Daniel, JM, additional, Sedding, DG, additional, Simionescu, N, additional, Sanda, GM, additional, Carnuta, MG, additional, Stancu, CS, additional, Popescu, AC, additional, Popescu, MR, additional, Vlad, A, additional, Dimulescu, DR, additional, Sima, AV, additional, Scoditti, E, additional, Pellegrino, M, additional, Calabriso, N, additional, Carluccio, MA, additional, Storelli, C, additional, De Caterina, R, additional, Solodenkova, KS, additional, Kalinina, EV, additional, Usachiova, MN, additional, Lappalainen, J, additional, Lee-Rueckert, M DE C, additional, Kovanen, PT, additional, Biesbroek, PS, additional, Emmens, RWE, additional, Van Rossum, AC, additional, Juffermans, LJM, additional, Niessen, JWM, additional, Krijnen, PAJ, additional, Kremzer, A, additional, Samura, T, additional, Berezina, T, additional, Gronenko, E, additional, Kim, MK, additional, Park, HJ, additional, Bae, SK, additional, Sorriento, D, additional, Ciccarelli, M, additional, Vernieri, E, additional, Campiglia, P, additional, Trimarco, B, additional, Iaccarino, G, additional, Hemmings, K E, additional, Porter, K E, additional, Ainscough, J F, additional, Drinkhill, M J, additional, Turner, N A, additional, Hiis, HG, additional, Cosson, MV, additional, Levy, FO, additional, Wieland, T, additional, Macquart, C, additional, Chatzifrangkeskou, M, additional, Evans, A, additional, Bonne, G, additional, Muchir, A, additional, Kemp, E, additional, Avkiran, M, additional, Carlomosti, F, additional, D'agostino, M, additional, Beji, S, additional, Zaccagnini, G, additional, Maimone, B, additional, Di Stefano, V, additional, De Santa, F, additional, Cordisco, S, additional, Antonini, A, additional, Ciarapica, R, additional, Dellambra, E, additional, Martelli, F, additional, Avitabile, D, additional, Scioli, MG, additional, Bielli, A, additional, Agostinelli, S, additional, Tarquini, C, additional, Tarallo, V, additional, De Falco, S, additional, Zaninoni, A, additional, Fiorelli, S, additional, Bianchi, P, additional, Teruzzi, G, additional, Squellerio, I, additional, Turnu, L, additional, Lualdi, A, additional, Tremoli, E, additional, Cavalca, V, additional, Lee, YJ, additional, Ju, ES, additional, Choi, JO, additional, Lee, GY, additional, Lim, BK, additional, Manickam, MANOJ, additional, Jung, S-H, additional, Omiya, S, additional, Otsu, K, additional, Deffge, C, additional, Nowak, S, additional, Wagner, M, additional, Braun-Dullaeus, RC, additional, Kostin, S, additional, Francke, A, additional, Subramaniam, S, additional, Kanse, SM, additional, Al-Lamee, K, 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2016
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47. The ATLAS Experiment at the CERN Large Hadron Collider

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Aad, G, Bentvelsen, S, Bobbink, G J, Bos, K, Boterenbrood, H, Brouwer, G, Buis, E J, Buskop, J J F, Colijn, A P, Dankers, R, Daum, C, de Boer, R, de Jong, P, Ennes, P, Gosselink, M, Groenstege, H, Hart, R G G, Hartjes, F, Hendriks, P J, Hessey, N P, Jansweijer, P P M, Kieft, G, Klous, S, Kluit, P, Koffeman, E, Koutsman, A, Liebig, W, Limper, M, Linde, F, Luijckx, G, Massaro, G, Muijs, A, Peeters, S J M, Reichold, A, Rewiersma, P, Rijpstra, M, Scholte, R C, Schuijlenburg, H W, Snuverink, J, van der Graaf, H, van der Kraaij, E, Van Eijk, B, van Kesteren, Z, van Vulpen, I, Verkerke, W, Vermeulen, J C, Vreeswijk, M, Werneke, P, Cakir, O, Ciftci, A K, Duran Yildiz, H, Sultanov, S, Turk Cakir, I, Yilmaz, M, Aubert, B, Bazan, A, Beaugiraud, B, Bellachia, F, Berger, N, Blaising, J J, Colas, J, Consonni, M, Delebecque, P, Delsart, P A, Di Ciaccio, L, Dayot, N Dumont>, Elles, S, Ghez, Philippe>, Girard, C G, Gouanere, M, Goy, C, Guillemin, T, Ionescu, G, Jeremie, A, Jezequel, S, Lafaye, R, Laplace, S, Marchand, J F, Massol, N, Neukermans, L, Perrodo, P, Perrot, G, Prast, J, Przysiezniak, H, Sauvage, G, Thion, J, Wingerter-Seez, I, Zitoun, R, Zolnierowski, Y, Baranov, S, Blair, R E, Cranshaw, J, Dawson, J W, Drake, G, Fullana Torregrosa, E, Gieraltowski, G F, Grudzinski, J, Guarino, V J, Hill, D, Hill, N, Karr, K, LeCompte, T, Lim, H, Malon, D, May, E N, Nodulman, L J, Petereit, E, Price, L E, Proudfoot, J, Schlereth, J L, Stanek, R W, Underwood, D G, van Gemmeren, P, Vaniachine, A, Yoshida, R, Zhang, J, Cheu, E, Johns, K A, Lampl, W, Loch, P, Rutherfoord, J P, Savine, A Y, Shaver, L, Shupe, M A, Tompkins, D, Varnes, E W, Alexopoulos, T, Avramidou, R, Dris, M, Filippas, A, Fokitis, M, Gazis, E N, Katsoufis, E, Maltezos, S, Papadopoulou, T, Savva, P, Tsipolitis, G, Tzamariudaki, E, Vlachos, S, Antonaki, A, Arabidze, G, Fassouliotis, D, Giakoumopoulou, V, Giokaris, N, Ioannou, P, Kourkoumelis, C, Manousakis-Katsikakis, A, Nikolopoulos, K, Tzanakos, G, Vellidis, C, Abdinov, O, Aliyev, M, Huseynov, N, Khalilzade, F, Biscarat, C, Blanch, O, Blumenschein, U, Bosman, M, Bravo, S, Casado, M P, Cavalli-Sforza, M, Deluca Silberberg, C, Domingo, E, Dosil, M, Espinal Curull, X, Fiorini, L, Flix, J, Garitaonandia, H, Iglesias Escudero, M C, Korolkov, I, Mir, L M, Verge, L Miralles>, Norniella Francisco, O, Osuna, C, Pacheco Pages, A, Padilla Aranda, C, Park, I, Perez Codina, E, Puigdengoles, C, Dachs, I Riu>, Ruiz, H, Salto Bauza, O, Sanchez Sanchez, C A, Segura, E, Sushkov, S, Vives Vaques, F, Volpi, M, Chen, T, Cheng, S, Feng, C, Han, H, Han, L, He, M, Jiang, Y, Jin, G, Jin, S, Lu, F, Ouyang, Q, Pei, E, Ping, J, Qi, M, Shan, L, Tong, G, Xie, Y, Xu, G, Yang, Y, Yu, X, Zhang, H, Zhang, X, Zheng, S, Zhu, C G, Krstic, J, Milosavljevic, M, Popovic, D S, Reljic, D, Sijacki, D, Simic, L, Vranjes, N, Vudragovic, M, Buanes, T, Eigen, G, Johansen, L G, Kastanas, A, Lipniacka, A, Mohn, B, Sandaker, H, Stugu, B, Tonoyan, A, Kolanoski, H, Kwee, R, Lohse, T, zur Nedden, M, Ambrosini, G, Beck, H P, Borer, K, Ereditato, A, Gjelsten, B K, Haeberli, C, Haug, S, Hess, M, Kabana, S, Kordas, K, Pretzl, K, Thomas, E, Topfel, C, Booth, J R A, Bright-Thomas, P G, Charlton, D G, Curtis, C J, Dowell, J D, Garvey, J, Hillier, S J, Hollins, T I, Homer, R J, Jovanovic, P, Mahout, G, McMahon, T J, Moye, T H, O'Neale, S W, Staley, R J, Thomas, J P, Typaldos, D, Watkins, P M, Watson, A T, Wilson, J A, Woehrling, E, Antonelli, S, Bellagamba, L, Bertin, A, Boscherini, D, Bruni, A, Bruni, G, Bruschi, M, Caforio, D, Corradi, M, De Castro, S, Fabbri, L, Faccioli, P, Giacobbe, B, Giusti, P, Grimaldi, F, Iacobucci, G, Massa, I, Mazzanti, P, Piccinini, M, Polini, A, Sbarra, C, Sbrizzi, A, Semprini-Cesari, N, Spighi, R, Villa, M, Vitale, A, Zoccoli, A, Ackers, M, Brock, I, Cammin, J, Cristinziani, M, Desch, K K, Dietsche, W, Eyring, A, Fischer, P, Fleischmann, S, Geich-Gimbel, C, Grosse-Knetter, J, Honerbach, W, Huegging, F, Karagounis, M, Klute, M, Kokott, T, Lehmacher, M, 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Unel, G, Wheeler-Ellis, S J, Chouridou, S, Dorfan, D E, Dubbs, T, Fadeyev, V, Grillo, A A, Hansl-Kozanecka, T, Litke, A M, Lockman, W S, Nielsen, J, Pequenao, J, Rosenbaum, F, Sadrozinski, H F W, Seiden, A, Spencer, E, Taylor, G, Batley, J R, Brochu, F M, Carter, J R, Frost, J A, Goodrick, M J, Hill, J C, Lester, C G, Munday, D J, Palmer, M J, Parker, M A, Phillips, A W, Robinson, D, Ward, C P, White, M J, Aleksa, M, Amaral, P, Amaral, S P, Amelung, C, Anghinolfi, F, Avolio, G, Bachy, G, Baltasar Dos Santos Pedrosa, F, Baron, S, Poy, A Barriuso>, Batraneanu, S, Battistin, M, Beltramello, O, Berge, D, Bergsma, F, Bertinelli, F, Bitadze, A, Blanchot, G, Bock, R, Bogaerts, J A, Boisvert, V, Bonneau, P, Boosten, M, Bosteels, M, Boyd, J, Braem, A, Bremer, J, Bujor, F, Burckhart, H, Burckhart-Chromek, D, Butin, F, Campana, S, Capeans Garrido, M D M, Cardiel Sas, L, Carli, T, Catinaccio, A, Cattai, A, Cernoch, C, Cerri, A, Chevalley, J L, Cook, J, Cornelissen, T, Da Silva, R, Danielsson, H O, 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Botchev, B, Engelmann, R, Finocchiaro, G, Goodson, J J, Grimm, K, Khodinov, A, McCarthy, R L, Rijssenbeek, M, Steffens, J L, Thioye, M, Yurkewicz, A, Grahn, K J, Hansson, P, Lund-Jensen, B, Tayalati, Y, Bergeaas, E, Berglund, S, Bohm, C, Clement, C, Eriksson, D, Gellerstedt, K, Hellman, S, Hidvegi, A, Holmgren, S O, Johansen, M, Johansson, K E, Jon-And, K, Lesser, J, Milstead, D A, Moa, T, Ramstedt, M, Sellden, B, Silverstein, S B, Lee, J S H, Peak, L S, Saavedra, A F, Varvell, K E, Waugh, A T, Chu, M L, Hou, S, Lee, S C, Lin, S C, Qing, D, Ren, Z, Teng, P K, Zhou, S, Zhou, Y, Chikovani, L, Djobava, T, Khubua, J, Mosidze, M, Tskhadadze, E G, Abramowicz, H, Alexander, G, Amram, N, Bella, G, Ben Moshe, M, Benary, O, Benhammou, Y, Brodet, E, Etzion, E, Ginzburg, J, Mahalalel, Y, Oren, Y, Reinherz-Aronis, E, Soffer, A, Urkovsky, E, De, K, Dipanjan, R, Farbin, A, Kim, H, Li, J, Nilsson, P, Ozturk, N, Pravahan, R, Sosebee, M, Spurlock, B, Vartapetian, A, White, A, Yu, J, Anastopoulos, C, Bachas, K, Bouzakis, K, Christidi, I A, Krepouri, A, Liolios, A, Petridou, C, Sampsonidis, D, Tsiafis, I, Bratzler, U, Fukunaga, C, Asai, S, Imori, M, Ishino, M, Kanaya, N, Kaneda, M, Kataoka, Y, Kawamoto, T, Kobayashi, T, Kubota, T, Mashimo, T, Matsumoto, H, Matsunaga, H, Nomoto, H, Okawa, H, Sakamoto, H, Tanaka, J, Ueda, I, Yamamoto, S, Bailey, D C, Gibson, A, Gorbounov, P A, Groer, L S, Guo, B, Joo, K K, Knecht, N K, Krieger, P, Le Maner, C, Ma, L L, Martens, F K, Mayer, J K, Mazini, R, Orr, R S, Rosenbaum, G A, Savard, P, Sinervo, P, Teuscher, R J, Trischuk, W, Amako, K, Arai, Y, Doi, Y, Haruyama, T, Ikegami, Y, Ikeno, M, Ishii, K, Iwasaki, H, Jinnouchi, O, Kagawa, S, Kanzaki, J, Kawai, M, Kohriki, T, Kondo, T, Kondo, Y, Makida, Y, Manabe, A, Murakami, K, Nagano, K, Nozaki, M, Odaka, S, Ozone, K, Sasaki, O, Sasaki, T, Tanaka, K, Terada, S, Tojo, J, Tokushuku, K, Tsuno, S, Unno, Y, Yamamoto, A, Yamaoka, H, Yasu, Y, Hara, K, Inoue, K, Kim, S H, Maruyama, T, Mochizuki, A, Nagai, Y, Nakamura, K, Nakamura, Y, Ukegawa, F, Mann, W A, Napier, A, Rolli, S, Sliwa, K, Todorova-Nova, S, Acharya, B S, Cauz, D, Cobal, M, De Lotto, B, Del Papa, C, Giordani, M P, Grassmann, H, Luisa, L, Santi, L, Belanger-Champagne, C, Bingefors, N, Brenner, R, Coniavitis, E, Ekelof, T, Ellert, M, Flechl, M, Hansen, C J, Lindquist, L, Ruber, R, Abdallah, J, Ballester, F, Bernabeu, J, Cabrera Urban, S, Cabruja Casas, E, Calderon Terol, D, Camarena, F, Campabadal Segura, F, Castelo, J, Castillo Gimenez, V, Civera, J V, Costa, M J, Almenar, C Cuenca>, Diez Cornell, S, Escobar, C, Fassi, F, Ferrer, A, Fleta Corral, C M, Fuster, J, Garcia, C, Garcia Navarro, J E, Gil Botella, Ines>, Gonzalez de la Hoz, S, Gonzalez Millan, V, Gonzalez-Sevilla, S, Higon-Rodriguez, E, Kaci, M, Lacasta, C, Lacuesta, V R, Lara, V, Llosa Llacer, G, Lozano Fantoba, M, Lopez-Amengual, J M, March, L, Marti i Garcia, S, Martinez Lacambra, C, Minano, M, Mitsou, V A, Modesto, P, Moles Valls, R M, Moreno, A, Pellegrini, G, Poveda, J, Rafi, J M, Roldan, J, Romance, J B, Ros, E, Ruiz-Martinez, A, Salt, J, Salvachua Ferrando, B M, Sanchis Lozano, M A, Sanchis Peris, E, Santander, J, Solans, C A, Medel, J Soret>, Suay, L Sospedra>, Sanchez, J, Torres Pais, J G, Ullan Comes, M, Valero, A, Valls Ferrer, J A, Vives, R, Vos, M, Axen, A, Gay, C, Loh, C W, Hodges, T A, Ishizawa, Y, Kurchaninov, L L, Langstaf, R R, Losty, M J, Moraes, A, Oram, C J, Tafirout, R, Trigger, I M, Walker, R, Wellisch, H P, Albert, J, Astbury, A, Berghaus, F, Courneyea, L, Fincke-Keeler, M, Honma, A, Ince, T, Keeler, R, Kowalewski, Robert V, Lefebvre, M, Lelas, D, Lessard, J R, McPherson, R A, Poffenberger, P, Seuster, R, Sobie, R, Taylor, R P, Voss, K C, Daly, C H, Forbush, D A, Gaudio, G, Kuykendall, W, Lubatti, H J, Mockett, P, Rothberg, J, Twomey, M S, Wang, J C, Watts, G, Zhao, T, Griesmayer, E, Chen, X, Dos Anjos, A, Fang, Y, Fasching, D, Ferguson, D, Flores Castillo, L R, Goldschmidt, N, Gonzalez, S, Jared, R C, Joseph, J, Leung Fook Cheong, A, Mellado Garcia, B R, Padhi, S, Pan, Y B, Quayle, W B, Stradling, A, Vickey, T, Wiedenmann, W, Wu, S L, Xu, N, Zobernig, G, Becks, K H, Bellina, F, Boek, J, Braun, Helmut M, Dima, M, Dopke, J, Drees, J, Flick, T, Gerlach, P, Glitza, K W, Gorfine, G, Grah, C, Gregor, I M, Hamacher, K, Harenberg, T, Henss, T, Kersten, S, Kind, P, Kootz, A, Lantzsch, K, Lenz, T, Lenzen, G, Lepidis, J, List, J, Mechtel, M, Meder-Marouelli, D, Pauna, E, Reeves, K, Sandhoff, M, Sandvoss, S, Sanny, B, Schultes, J, Siebel, A, Thadome, J, Wahlen, H, Wicke, D, Zeitnitz, C, Auerbach, B, Baker, O K, Kaplan, B, Loginov, A, Lokwitz, S, Martin, A J, Schmidt, M P, Tipton, P, Wall, R, Zeller, M, Jorgensen, S, Oye, O K, Buscher, V, Kruger, H, Moser, N, Rottlander, I, von Torne, E, Akesson, P F, Demirkoz, B, Grafstrom, P, Kotamaki, M J, Gossling, C, Luke, D, Wustenfeld, J, Gopfert, T, Duhrssen, M, Konig, S, Duren, M, Mattig, S, Monig, K, Fohlisch, F, Ruhr, F, Dur, H, Akesson, T P A, Mjornmark, J U, Soderberg, M, Kopke, L, Schafer, U, Muller, M, Gottfert, T, Hartel, R, Mohrdieck-Mock, S, Schmucker, H, Strohmer, R, Konig, A C, Rohne, O, Asman, B, Engstrom, M, Sjolin, J, Imhauser, M, Mattig, P, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), APC - Neutrinos, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), ATLAS, AAD G., ABAT E., ABDALLAH J., ABDELALIM AA., ABDESSELAM A., ABDINOV O., ABI BA., ABOLINS M., ABRAMOWICZ H., ACERBI E., ACHARYA BS., ACHENBACH R., ACKERS M., ADAMS DL., ADAMYAN F., ADDY TN., ADERHOLZ M., ADORISIO C., ADRAGNA P., AHARROUCHE M., AHLEN SP., AHLES F., AHMAD A., AHMED H., AIELLI G., AKESSON PF., AKESSON TPA., ALAM SM., ALBERT J., ALBRAND S., ALEKSA M., ALEKSANDROV IN., ALEPPO M., ALESSANDRIA F., ALEXA C., ALEXANDER G., ALEXOPOULOS T., ALIMONTI G., ALIYEV M., ALLPORT PP., ALLWOOD-SPIERS SE., ALOISIO A., ALONSO J., ALVES R., ALVIGGI MG., AMAKO K., AMARAL P., AMARAL SP., AMBROSINI G., AMBROSIO G., AMELUNG C., AMMOSOV VV., AMORIM A., AMRAM N., ANASTOPOULOS C., ANDERSON B., ANDERSON KJ., ANDERSSEN EC., ANDREAZZA A., ANDREI V., ANDRICEK L., ANDRIEUX ML., ANDUAGA XS., ANGHINOLFI F., ANTONAKI A., ANTONELLI M., ANTONELLI S., APSIMON R., ARABIDZE G., ARACENA I., ARAI Y., ARCE ATH., ARCHAMBAULT JP., ARGUIN JF., ARIK E., ARIK M., ARMS KE., ARMSTRONG SR., ARNAUD M., ARNAULT C., ARTAMONOV A., ASAI S., ASK S., ASMAN B., ASNER D., ASQUITH L., ASSAMAGAN K., ASTBURY A., ATHAR B., ATKINSON T., AUBERT B., AUERBACH B., AUGE E., AUGSTEN K., AULCHENKO VM., AUSTIN N., AVOLIO G., AVRAMIDOU R., AXEN A., AY C., AZUELOS G., BACCAGLIONI G., BACCI C., BACHACOU H., BACHAS K., BACHY G., BADESCU E., BAGNAIA P., BAILEY DC., BAINES JT., BAKER OK., BALLESTER F., PEDROSA FBDS., BANAS E., BANFI D., BANGERT A., BANSAL V., BARANOV SP., BARANOV S., BARASHKOU A., BARBERIO EL., BARBERIS D., BARBIER G., BARCLAY P., BARDIN DY., BARGASSA P., BARILLARI T., BARISONZI M., BARNETT BM., BARNETT RM., BARON S., BARONCELLI A., BARONE M., BARR AJ., BARREIRO F., DA COSTA JBG., BARRILLON P., POY AB., BARROS N., BARTHELD V., BARTKO H., BARTOLDUS R., BASILADZE S., BASTOS J., BATCHELOR LE., BATES RL., BATLEY JR., BATRANEANU S., BATTISTIN M., BATTISTONI G., BATUSOV V., BAUER F., BAUSS B., BAYNHAM DE., BAZALOVA M., BAZAN A., BEAUCHEMIN PH., BEAUGIRAUD B., BECCHERLE RB., BECK GA., BECK HP., BECKS KH., BEDAJANEK I., BEDDALL AJ., BEDDALL A., BEDNAR P., BEDNYAKOV VA., BEE C., HARPAZ SB., BELANGER GAN., BELANGER-CHAMPAGNE C., BELHORMA B., BELL PJ., BELL WH., BELLA G., BELLACHIA F., BELLAGAMBA L., BELLINA F., BELLOMO G., BELLOMO M., BELTRAMELLO O., BELYMAM A., BEN AMI S., BEN MOSHE M., BENARY O., BENCHEKROUN D., BENCHOUK C., BENDEL M., BENEDICT BH., BENEKOS N., BENES J., BENHAMMOU Y., BENINCASA GP., BENJAMIN DP., BENSINGER JR., BENSLAMA K., BENTVELSEN S., BERETTA M., BERGE D., BERGEAAS E., BERGER N., BERGHAUS F., BERGLUND S., BERGSMA F., BERINGER J., BERNABEU J., BERNARDET K., BERRIAUD C., BERRY T., BERTELSEN H., BERTIN A., BERTINELLI F., BERTOLUCCI S., BESSON N., BETEILLE A., BETHKE S., BIALAS W., BIANCHI RM., BIANCO M., BIEBEL O., BIERI M., BIGLIETTI M., BILOKON H., BINDER M., BINET S., BINGEFORS N., BINGUL A., BINI C., BISCARAT C., BISCHOF R., BISCHOFBERGER M., BITADZE A., BIZZELL JP., BLACK KM., BLAIR RE., BLAISING JJ., BLANCH O., BLANCHOT G., BLOCKER C., BLOCKI J., BLONDEL A., BLUM W., BLUMENSCHEIN U., BOARETTO C., BOBBINK GJ., BOCCI A., BOCIAN D., BOCK R., BOEHM M., BOEK J., BOGAERTS JA., BOGOUCH A., BOHM C., BOHM J., BOISVERT V., BOLD T., BOLDEA V., BONDARENKO VG., BONINO R., BONIS J., BONIVENTO W., BONNEAU P., BOONEKAMP M., BOORMAN G., BOOSTEN M., BOOTH CN., BOOTH PSL., BOOTH P., BOOTH JRA., BORER K., BORISOV A., BORJANOVIC I., BOS K., BOSCHERINI D., BOSI F., BOSMAN M., BOSTEELS M., BOTCHEV B., BOTERENBROOD H., BOTTERILL D., BOUDREAU J., BOUHOVA-THACKER EV., BOULAHOUACHE C., BOURDARIOS C., BOUTEMEUR M., BOUZAKIS K., BOYD GR., BOYD J., BOYER BH., BOYKO IR., BOZHKO NI., BRACCINI S., BRAEM A., BRANCHINI P., BRANDENBURG GW., BRANDT A., BRANDT O., BRATZLER U., BRAUN HM., BRAVO S., BRAWN IP., BRELIER B., BREMER J., BRENNER R., BRESSLER S., BRETON D., BRETT ND., BREUGNON P., BRIGHT-THOMAS PG., BROCHU FM., BROCK I., BROCK R., BRODBECK TJ., BRODET E., BROGGI F., BROKLOVA Z., BROMBERG C., BROOIJMANS G., BROUWER G., BROZ J., BRUBAKER E., DE RENSTROM PAB., BRUNCKO D., BRUNI A., BRUNI G., BRUSCHI M., BUANES T., BUCHANAN NJ., BUCHHOLZ P., BUDAGOV IA., BUSCHER V., BUGGE L., BUIRA-CLARK D., BUIS EJ., BUJOR F., BURAN T., BURCKHART H., BURCKHART-CHROMEK D., BURDIN S., BURNS R., BUSATO E., BUSKOP JJF., BUSZELLO KP., BUTIN F., BUTLER JM., BUTTAR CM., BUTTERWORTH J., BUTTERWORTH JM., BYATT T., URBAN SC., CASAS EC., CACCIA M., CAFORIO D., CAKIR O., CALAFIURA P., CALDERINI G., TEROL DC., CALLAHAN J., CALOBA LP., CALOI R., CALVET D., CAMARD A., CAMARENA F., CAMARRI P., CAMBIAGHI M., CAMERON D., CAMMIN J., SEGURA FC., CAMPANA S., CANALE V., CANTERO J., GARRIDO MDMC., CAPRINI I., CAPRINI M., CAPRIO M., CARACINHA D., CARAMARCU C., CARCAGNO Y., CARDARELLI R., CARDEIRA C., SAS LC., CARDINI A., CARLI T., CARLINO G., CARMINATI L., CARON B., CARON S., CARPENTIERI C., CARR FS., CARTER AA., CARTER JR., CARVALHO J., CASADEI D., CASADO MP., CASCELLA M., CASO C., CASTELO J., GIMENEZ VC., CASTRO N., CASTROVILLARI F., CATALDI G., CATANEO F., CATINACCIO A., CATMORE JR., CATTAI A., CAUGHRON S., CAUZ D., CAVALLARI A., CAVALLERI P., CAVALLI D., CAVALLI-SFORZA M., CAVASINNI V., CERADINI F., CERNA C., CERNOCH C., CERQUEIRA AS., CERRI A., CERUTTI F., CERVETTO M., CETIN SA., CEVENINI F., CHALIFOUR M., ILATAS MC., CHAN A., CHAPMAN JW., CHARLTON DG., CHARRON S., CHEKULAEV SV., CHELKOV GA., CHEN H., CHEN L., CHEN T., CHEN X., CHENG S., CHENG TL., CHEPLAKOV A., CHEPURNOV VF., EL MOURSLI RC., CHESNEANU D., CHEU E., CHEVALIER L., CHEVALLEY JL., CHEVALLIER F., CHIARELLA V., CHIEFARI G., CHIKOVANI L., CHILINGAROV A., CHIODINI G., CHOURIDOU S., CHREN D., CHRISTIANSEN T., CHRISTIDI IA., CHRISTOV A., CHU ML., CHUDOBA J., CHUGUEV AG., CIAPETTI G., CICALINI E., CIFTCI AK., CINDRO V., CIOBOTARU MD., CIOCIO A., CIRILLI M., CITTERIO M., CIUBANCAN M., CIVERA JV., CLARK A., CLELAND W., CLEMENS JC., CLEMENT BC., CLEMENT C., CLEMENTS D., CLIFFT RW., COBA M., COCCARO A., COCHRAN J., COCO R., COE P., COELLI S., COGNERAS E., COJOCARU CD., COLAS J., COLIJN AP., COLLARD C., COLLINS-TOOTH C., COLLOT J., COLUCCIA R., COMUNE G., MUINO PC., CONIAVITIS E., CONSONNI M., CONSTANTINESCU S., CONTA C., CONVENTI FA., COOK J., COOKE M., COOPER-SMITH NJ., CORNELISSEN T., CORRADI M., CORREARD S., CORSO-RADU A., COSS J., COSTA G., COSTA MJ., COSTANZO D., COSTIN T., TORRES RC., COURNEYEA L., COUYOUMTZELIS C., COWAN G., COX BE., COX J., CRAGG DA., CRANMER K., CRANSHAW J., CRISTINZIANI M., CROSETTI G., ALMENAR CC., CUNEO S., CUNHA A., CURATOLO M., CURTIS CJ., CWETANSKI P., CZYCZULA Z., D'AURIA S., D'ONOFRIO M., MELLO ADG., DA SILVA PVM., DA SILVA R., DABROWSKI W., DAEL A., DAHLHOFF A., DAI T., DALLAPICCOLA C., DALLISON SJ., DALMAU J., DALY CH., DAM M., DAMAZIO D., DAMERI M., DANIELSEN KM., DANIELSSON HO., DANKERS R., DANNHEIM D., DARBO G., DARGENT P., DAUM C., DAUVERGNE JP., DAVID M., DAVIDEK T., DAVIDSON N., DAVIDSON R., DAWSON I., DAWSON JW., DAYA RK., DE K., DE ASMUNDIS R., DE BOER R., DE CASTRO S., DE GROOT N., DE JONG P., DE LA BROISE X., DE LA CRUZ-BURELO E., DE LA TAILLE C., DE LOTTO B., BRANCO MDO., DE PEDIS D., DE SAINTIGNON P., DE SALVO A., DE SANCTIS U., DE SANTO A., DE REGIE JBDV., DE ZORZI G., DEAN S., DEDES G., DEDOVICH DV., DEFAY PO., DEGELE R., DEHCHAR M., DEILE M., DEL PAPA C., DEL PESO J., DEL PRETE T., DELAGNES E., DELEBECQUE P., DELL'ACQUA A., PIETRA MD., DELLA VOLPE D., DELMASTRO M., DELPIERRE P., DELRUELLE N., DELSART PA., SILBERBERG CD., DEMERS S., DEMICHEV M., DEMIERRE P., DEMIRKOZ B., DENG W., DENISOV SP., DENNIS C., DENSHAM CJ., DENTAN M., DERKAOUI JE., DERUE F., DERVAN P., DESCH KK., DEWHURST A., DI CIACCIO A., DI CIACCIO L., DI DOMENICO A., DI GIROLAMO A., DI GIROLAMO B., DI LUISE S., DI MATTIA A., DI SIMONE A., GOMEZ MMD., DIEHL EB., DIETL H., DIETRICH J., DIETSCHE W., DIGLIO S., DIMA M., DINDAR K., DINKESPILER B., DIONISI C., DIPANJAN R., DITA P., DITA S., DITTUS F., DIXON SD., DJAMA F., DJILKIBAEV R., DJOBAVA T., DO VALE MAB., DOBBS M., DOBINSON R., DOBOS D., DOBSON E., DOBSON M., DODD J., DOGAN OB., DOHERTY T., DOI Y., DOLEJSI J., DOLENC I., DOLEZA Z., DOLGOSHEIN BA., DOMINGO E., DONEGA M., DOPKE J., DORFAN DE., DORHOLT O., DORIA A., DOS ANJOS A., DOSIL M., DOTTI A., DOVA MT., DOWELL JD., DOYLE AT., DRAKE G., DRAKOULAKOS D., DRASAL Z., DREES J., DRESSNANDT N., DREVERMANN H., DRIOUICHI C., DRIS M., DROHAN JG., DUBBERT J., DUBBS T., DUCHOVNI E., DUCKECK G., DUDAREV A., DUHRSSEN M., DUR H., DUERDOTH IP., DUFFIN S., DUFLOT L., DUFOUR MA., DAYOT ND., YILDIZ HD., DURAND D., DUSHKIN A., DUXFIELD R., DWUZNIK M., DYDAK F., DZAHINI D., CORNELL SD., DUREN M., EBENSTEIN WL., ECKERT S., ECKWEILER S., EEROLA P., EFTHYMIOPOULOS I., EGEDE U., EGOROV K., EHRENFELD W., EIFERT T., EIGEN G., EINSWEILER K., EISENHANDLER E., EKELOF T., EKLUND LM., EL KACIMI M., ELLERT M., ELLES S., EILIS N., ELMSHEUSER J., ELSING M., ELY R., EMELIYANOV D., ENGELMANN R., ENGSTROM M., ENNES P., EPP B., EPPIG A., EPSHTEYN VS., EREDITATO A., EREMIN V., ERIKSSON D., ERMOLINE I., ERNWEIN J., ERREDE D., ERREDE S., ESCALIER M., ESCOBAR C., CURULL XE., ESPOSITO B., ESTEVES F., ETIENNE F., ETIENVRE AI., ETZION E., EVANS H., EVDOKIMOV VN., EVTOUKHOVITCH P., EYRING A., FABBRI L., FABJAN CW., FABRE C., FACCIOLI P., FACIUS K., FADEYEV V., FAKHRUTDINOV RM., FALCIANO S., FALLEAU I., FALOU AC., FANG Y., FANTI M., FARBIN A., FARILLA A., FARRELL J., FARTHOUAT P., FASCHING D., FASSI F., FASSNACHT P., FASSOULIOTIS D., FAWZI F., FAYARD L., FAYETTE F., FEBBRARO R., FEDIN OL., FEDORKO I., FELD L., FELDMAN G., FELIGIONI L., FENG C., FENG EJ., FENT J., FENYUK AB., FERENCEI J., FERGUSON D., FERLAND J., FERNANDO W., FERRAG S., FERRARI A., FERRARI P., FERRARI R., FERRER A., FERRER ML., FERRERE D., FERRETTI C., FERRO F., FIASCARIS M., FICHET S., FIEDLER F., FILIMONOV V., FILIPCIC A., FILIPPAS A., FILTHAUT F., FINCKE-KEELER M., FINOCCHIARO G., FIORINI L., FIRAN A., FISCHER P., FISHER MJ., FISHER SM., FLAMINIO V., FLAMMER J., FLECHL M., FLECK I., FLEGEL W., FLEISCHMANN P., FLEISCHMANN S., CORRAL CMF., FLEURET F., FLICK T., FLIX J., CASTILLO LRF., FLOWERDEW MJ., FOHLISCH F., FOKITIS M., MARTIN TMF., FOPMA J., FORBUSH DA., FORMICA A., FOSTER JM., FOURNIER D., FOUSSAT A., FOWLER AJ., FOX H., FRANCAVILLA P., FRANCIS D., FRANZ S., FRASER JT., FRATERNALI M., FRATIANNI S., FREESTONE J., FRENCH RS., FRITSCH K., FROIDEVAUX D., FROST JA., FUKUNAGA C., FULACHIER J., TORREGROSA EF., FUSTER J., GABALDON C., GADOMSKI S., GAGLIARDI G., GAGNON P., GALLAS EJ., GALLAS MV., GALLOP BJ., GAN KK., GANNAWAY FC., GAO YS., GAPIENKO VA., GAPONENKO A., GARCIA C., GARCIA-SCIVERES M., NAVARRO JEG., GARDE V., GARDNER RW., GARELLI N., GARITAONANDIA H., GARONNE VG., GARVEY J., GATTI C., GAUDIO G., GAUMER O., GAUTARD V., GAUZZI P., GAVRILENKO IL., GAY C., GAYDE JC., GAZIS EN., GAZO E., GEE CNP., GEICH-GIMBEL C., GELLERSTEDT K., GEMME C., GENEST MH., GENTILE S., GEORGE MA., GEORGE S., GERLACH P., GERNIZKY Y., GEWENIGER C., GHAZLANE H., GHETE VM., GHEZ P., GHODBANE N., GIACOBBE B., GIAGU S., GIAKOUMOPOULOU V., GIANGIOBBE V., GIANOTTI F., GIBBARD B., GIBSON A., GIBSON MD., GIBSON SM., GIERALTOWSKI GF., BOTELLA IG., GILBERT LM., GILCHRIESE M., GILDEMEISTER O., GILEWSKY V., GILLMAN AR., GINGRICH DM., GINZBURG J., GIOKARIS N., GIORDANI MP., GIRARD CG., GIRAUD PF., GIRTLER P., GIUGNI D., GIUSTI P., GJELSTEN BK., GLASMAN C., GLAZOV A., GLITZA KW., GLONTI GL., GNANVO KG., GODLEWSKI J., GOPFERT T., GOSSLING C., GOTTFERT T., GOLDFARB S., GOLDIN D., GOLDSCHMIDT N., GOLLING T., GOLLUB NP., GOLONKA PJ., GOLOVNIA SN., GOMES A., GOMES J., GONCALO R., GONGADZE A., GONIDEC A., GONZALEZ S., DE LA HOZ SG., MILLAN VG., SILVA MLG., GONZALEZ-PINEIRO B., GONZALEZ-SEVILLA S., GOODRICK MJ., GOODSON JJ., GOOSSENS L., GORBOUNOV PA., GORDEEV A., GORDON H., GORELOV I., GORFINE G., GORINI B., GORINI E., GORISEK A., GORNICKI E., GOROKHOV SA., GORSKI BT., GORYACHEV SV., GORYACHEV VN., GOSSELINK M., GOSTKIN MI., GOUANERE M., ESCHRICH IG., GOUJDAMI D., GOULETTE M., GOUSAKOV I., GOUVEIA J., GOWDY S., GOY C., GRABOWSKA-BOLD I., GRABSKI V., GRAFSTROM P., GRAH C., GRAHN KJ., GRANCAGNOLO F., GRANCAGNOLO S., GRASSMANN H., GRATCHEV V., GRAY HM., GRAZIANI E., GREEN B., GREENA A., GREENFIELD D., GREENWOOD D., GREGOR IM., GREWAL A., GRIESMAYER E., GRIGALASHVILI N., GRIGSON C., GRILLO AA., GRIMALDI F., GRIMM K., GRIS PLY., GRISHKEVICH Y., GROENSTEGE H., GROER LS., GROGNUZ J., GROH M., GROSS E., GROSSE-KNETTER J., GROTHE MEM., GRUDZINSKI J., GRUSE C., GRUWE M., GRYBEL K., GRYBOS P., GSCHWENDTNER EM., GUARINO VJ., GUICHENEY CJ., GUILHEM G., GUILLEMIN T., GUNTHER J., GUO B., GUPTA A., GURRIANA L., GUSHCHIN VN., GUTIERREZ P., GUY L., GUYOT C., GWENLAN C., GWILLIAM CB., HAAS A., HAAS S., HABER C., HABOUBI G., HACKENBURG R., HADASH E., HADAVAND HK., HAEBERLI C., HARTEL R., HAGGERTY R., HAHN F., HAIDER S., HAJDUK Z., HAKIMI M., HAKOBYAN H., HALLER J., HALLEWELL GD., HALLGREN B., HAMACHER K., HAMILTON A., HAN H., HAN L., HANAGAKI K., HANCE M., HANKE P., HANSEN CJ., HANSEN FH., HANSEN JR., HANSEN JB., HANSEN JD., HANSEN PH., HANSL-KOZANECKA T., HANSON G., HANSSON P., HARA K., HARDER S., HAREL A., HARENBERG T., HARPER R., HART JC., HART RGG., HARTJES F., HARTMAN N., HARUYAMA T., HARVEY A., HASEGAWA Y., HASHEMI K., HASSANI S., HATCH M., HATLEY RW., HAUBOLD TG., HAUFF D., HAUG F., HAUG S., HAUSCHILD M., HAUSER R., HAUVILLER C., HAVRANEK M., HAWES BM., HAWKINGS RJ., HAWKINS D., HAYLER T., HAYWARD HS., HAYWOOD SJ., HAZEN E., HE M., HE YP., HEAD SJ., HEDBERG V., HEELAN L., HEINEMANN FEW., HELDMANN M., HELLMAN S., HELSENS C., HENDERSON RCW., HENDRIKS PJ., CORREIA AMH., HENROT-VERSILLE S., HENRY-COUANNIER F., HENSS T., HERTEN G., HERTENBERGER R., HERVAS L., HESS M., HESSEY NP., HICHEUR A., HIDVEGI A., HIGON-RODRIGUEZ E., HILL D., HILL J., HILL JC., HILL N., HILLIER SJ., HINCHLIFFE I., HINDSON D., HINKELBEIN C., HODGES TA., HODGKINSON MC., HODGSON P., HOECKER A., HOEFERKAMP MR., HOFFMAN J., HOFFMANN AE., HOFFMANN D., HOFFMANN HF., HOLDER M., HOLLINS TI., HOLLYMAN G., HOLMES A., HOLMGREN SO., HOLT R., HOLTOM E., HOLY T., HOMER RJ., HOMMA Y., HOMOLA P., HONERBACH W., HONMA A., HOOTON I., HORAZDOVSKY T., HORN C., HORVAT S., HOSTACHY JY., HOTT T., HOU S., HOULDEN MA., HOUMMADA A., HOVER J., HOWELL DF., HRIVNAC J., HRUSKA I., HRYN'OVA T., HUANG GS., HUBACEK Z., HUBAUT F., HUEGGING F., HUFFMAN BT., HUGHES E., HUGHES G., HUGHES-JONES RE., HULSBERGEN W., HURST P., HURWITZ M., HUSE T., HUSEYNOV N., HUSTON J., HUTH J., IACOBUCCI G., IBBOTSON M., IBRAGIMOV I., ICHIMIYA R., ICONOMIDOU-FAYARD L., IDARRAGA J., IDZIK M., IENGO P., ESCUDERO MCI., IGONKINA O., IKEGAMI Y., IKENO M., ILCHENKO Y., ILYUSHENKA Y., IMBAULT D., IMBERT P., IMHAEUSER M., IMORI M., INCE T., INIGO-GOLFIN J., INOUE K., IOANNOU P., IODICE M., IONESCU G., ISHII K., ISHINO M., ISHIZAWA Y., ISHMUKHAMETOV R., ISSEVER C., ITO H., IVASHIN AV., IWANSKI W., IWASAKI H., IZEN JM., IZZO V., JACKSON J., JACKSON JN., JAEKEL M., JAGIELSKI S., JAHODA M., JAIN V., JAKOBS K., JAKUBEK J., JANSEN E., JANSWEIJER PPM., JARED RC., JARLSKOG G., JARP S., JARRON P., JELEN K., PLANTE IJL., JENNI P., JEREMIE A., JEZ P., JEZEQUEL S., JIANG Y., JIN G., JIN S., JINNOUCHI O., JOFFE D., JOHANSEN LG., JOHANSEN M., JOHANSSON KE., JOHANSSON P., JOHNS KA., JON-AND K., JONES M., JONES R., JONES RWL., JONES W., JONES TJ., JONES A., JONSSON O., JOO KK., JOOS D., JOOS M., JORAM C., JORGENSEN S., JOSEPH J., JOVANOVIC P., JUNNARKAR SS., JURANEK V., JUSSEL P., KABACHENKO VV., KABANA S., KACI M., KACZMARSKA A., KADO M., KAGAN H., KAGAWA S., KAISER S., KAJOMOVITZ E., KAKURIN S., KALINOVSKAYA LV., KAMA S., KAMBARA H., KANAYA N., KANDASAMY A., KANDASAMY S., KANEDA M., KANTSEROV VA., KANZAKI J., KAPLAN B., KAPLIY A., KAPLON J., KARAGOUNIS M., UNEL MK., KARR K., KARST P., KARTVELISHVILI V., KARYUKHIN AN., KASHIF L., KASMI A., KASS RD., KASTANAS A., KATAOKA M., KATAOKA Y., KATSOUFIS E., KATUNIN S., KAWAGOE 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SUBRAMANIA S., SUCHKOV SI., SUGAYA Y., SUGIMOTO T., SUK M., SULIN VV., SULTANOV S., SUN Z., SUNDAL B., SUSHKOV S., SUSINNO G., SUTCLIFFE P., SUTTON MR., SVIRIDOV YM., SYKORA I., SZCZYGIEL RR., SZELESS B., SZYMOCHA T., SANCHEZ J., TA D., GAMEIRO ST., TADEL M., TAFIROUT R., TAGA A., TAKAI H., TAKASHIMA R., TAKEDA H., TAKESHITA T., TALBY M., TALYSHEV A., TAMSETT MC., TANAKA J., TANAKA K., TANAKA R., TANAKA S., TANAKA Y., TAPPERN GP., TAPPROGGE S., TAREM S., TARRADE F., TARRANT J., TARTARELLI G., TAS P., TASEVSKY M., TAYALATI Y., TAYLOR FE., TAYLOR G., TAYLOR GN., TAYLOR RP., TCHERNIATINE V., TEGENFELDT F., TEIXEIRA-DIAS P., TEN KATE H., TENG PK., TER-ANTONYAN R., TERADA S., TERRON J., TERWORT M., TEUSCHER RJ., TEVLIN CM., THADOME J., THION J., THIOYE M., THOMAS A., THOMAS JP., THOMAS TL., THOMAS E., THOMPSON RJ., THOMPSON AS., THUN RP., TIC T., TIKHOMIROV VO., TIKHONOV YA., TIMM S., TIMMERMANS CJWP., TIPTON P., VIEGAS FJTA., TISSERANT S., TITOV M., TOBIAS J., TOCUT VM., TOCZEK B., TODOROVA-NOVA S., TOJO J., TOKAR S., TOKUSHUKU K., TOMASEK L., TOMASEK M., TOMASZ F., TOMOTO M., TOMPKINS D., TOMPKINS L., TOMS K., TONAZZO A., TONG G., TONOYAN A., TOPFEL C., TOPILIN ND., TORRENCE E., PAIS JGT., TOTH J., TOUCHARD F., TOVEY DR., TOVEY SN., TOWNDROW EF., TREFZGER T., TREICHEL M., TREIS J., TREMBLET L., TRIBANEK W., TRICOLI A., TRIGGER IM., TRILLING G., TRINCAZ-DUVOID S., TRIPIANA MF., TRISCHUK W., TRKA Z., TROCME B., TRONCON C., TSENG JCL., TSIAFIS I., TSIARESHKA PV., TSIPOLITIS G., TSKHADADZE EG., TSUKERMAN II., TSULAIA V., TSUNO S., TURALA M., CAKIR IT., TURLAY E., TUTS PM., TWOMEY MS., TYNDE M., TYPALDOS D., TYRVAINEN H., TZAMARIOUDAKI E., TZANAKOS G., UEDA I., UHRMACHER M., UKEGAWA F., COMES MU., UNAL G., UNDERWOOD DG., UNDRUS A., UNEL G., UNNO Y., URKOVSKY E., USAI G., USOV Y., VACAVANT L., VACEK V., VACHON B., VAHSEN S., VALDERANIS C., VALENTA J., VALENTE P., VALERO A., VALKAR S., FERRER JAV., VAN DER BIJ H., VAN DER GRAAF H., VAN DER KRAAIJ E., VAN EIJK B., VAN ELDIK N., VAN GEMMEREN P., VAN KESTEREN Z., VAN VULPEN I., VANBERG R., VANDELLI W., VANDONI G., VANIACHINE A., VANNUCCI F., VARANDA M., RODRIGUEZ FV., VARI R., VARNES EW., VAROUCHAS D., VARTAPETIAN A., VARVE KE., VASSILAKOPOULOS VI., VASSILIEVA L., VATAGA E., VAZ L., VAZEILLE F., VEDRINE P., VEGNI G., VEILLET JJ., VELLIDIS C., VELOSO F., VENESS R., VENEZIANO S., VENTURA A., VENTURA S., VERCESI V., VERDUCCI M., VERKERKE W., VERMEULEN JC., VERTOGARDOV L., VETTERLI MC., VICHOU I., VICKEY T., VIEHHAUSER GHA., VIGEOLAS E., VILLA M., VILLANI EG., VILLATE J., VILLELLA I., VILUCCHI E., VINCENT P., VINCKE H., VINCTER MG., VINOGRADOV VB., VIRCHAUX M., VIRET S., VIRZI J., VITALE A., VIVARELLI I., VIVES R., VAQUES FV., VLACHOS S., VOGT H., VOKAC P., VOLLMER CF., VOLPI M., VOLPINI G., VON BOEHN-BUCHHOLZ R., VON DER SCHMITT H., VON TOERNE E., VOROBEL V., VOROBIEV AP., VOROZHTSOV AS., VOROZHTSOV SB., VOS M., VOSS KC., VOSS R., VOSSEBELD JH., VOVENKO AS., VRANJES N., VRBA V., VREESWIJK M., ANH TV., VUARIDEL B., VUDRAGOVIC M., VUILLEMIN V., VUILLERMET R., WANANEN A., WAHLEN H., WALBERSLOH J., WALKER R., WALKOWIAK W., WALL R., WALLNY RS., WALSH S., WANG C., WANG JC., WAPPLER F., WARBURTON A., WARD CP., WARNER GP., WARREN M., WARSINSKY M., WASTIE R., WATKINS PM., WATSON AT., WATTS G., WAUGH AT., WAUGH BM., WEAVERDYCK C., WEBEL M., WEBER G., WEBER J., WEBER M., WEBER P., WEIDBERG AR., WEILHAMMER PM., WEINGARTEN J., WEISER C., WELLENSTEIN H., WELLISCH HP., WELLS P., WEMANS A., WEN M., WENAUS T., WENDLER S., WENGLER T., WENIG S., WERMES N., WERNEKE P., WERNER P., WERTHENBACH U., WHEELER-ELLIS SJ., WHITAKER SP., WHITE A., WHITE MJ., WHITE S., WHITTINGTON D., WICEK F., WICKE D., WICKENS FJ., WIEDENMANN W., WIELERS M., WIENEMANN P., WIESMANN M., WIJNEN T., WILDAUER A., WILHELM I., WILKENS HG., WILLIAMS HH., WILLIS W., WILLOCQ S., WILMUT I., WILSON JA., WILSON A., WINGERTER-SEEZ I., WINTON L., WITZELING W., WLODEK T., WOEHRLING E., WOLTER MW., WOLTERS H., WOSIEK B., WOTSCHACK J., WOUDSTRA MJ., WRIGHT C., WU SL., WU X., WUESTENFELD J., WUNSTORF R., XELLA-HANSEN S., XIANG A., XIE S., XIE Y., XU G., XU N., YAMAMOTO A., YAMAMOTO S., YAMAOKA H., YAMAZAKI Y., YAN Z., YANG H., YANG JC., YANG S., YANG UK., YANG Y., YANG Z., YAO WM., YAO Y., YARRADODDI K., YASU Y., YE J., YILMAZ M., YOOSOOFMIYA R., YORITA K., YOSHIDA H., YOSHIDA R., YOUNG C., YOUSSEF SP., YU D., YU J., YU M., YU X., YUAN J., YURKEWICZ A., ZAETS VG., ZAIDAN R., ZAITSEV AM., ZAJAC J., ZAJACOVA Z., ZALITE AY., ZALITE YK., ZANEO L., ZARZHITSKY P., ZAYTSEV A., ZDRAZIL M., ZEITNITZ C., ZELLER M., ZEMA PF., ZENDLER C., ZENIN AV., ZENIS T., ZENONOS Z., ZENZ S., ZERWAS D., ZHANG H., ZHANG J., ZHENG W., ZHANG X., ZHAO L., ZHAO T., ZHAO X., ZHAO Z., ZHELEZKO A., ZHEMCHUGOV A., ZHENG S., ZHICHAO L., ZHOU B., ZHOU N., ZHOU S., ZHOU Y., ZHU CG., ZHU HZ., ZHUANG XA., ZHURAVLOV V., ZILKA B., ZIMIN NI., ZIMMERMANN S., ZIOLKOWSKI M., ZITOUN R., ZIVKOVIC L., ZMOUCHKO VV., ZOBERNIG G., ZOCCOLI A., ZOELLER MM., ZOLNIEROWSKI Y., ZSENEI A., ZUR NEDDEN M., ZYCHACEK V., Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), G., Aad, Aloisio, Alberto, Alviggi, Mariagrazia, Canale, Vincenzo, Cevenini, Francesco, Chiefari, Giovanni, DELLA VOLPE, Domenico, Merola, Leonardo, Patricelli, Sergio, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Bianco, Michele, G., Cataldi, G., Chiodini, Coluccia, MARIA RITA, Gorini, Edoardo, F., Grancagnolo, Grancagnolo, Sergio, R., Perrino, Primavera, Margherita, Siragusa, Giovanni, Spagnolo, Stefania Antonia, Ventura, Andrea, Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, Abdelalim Aly, Ahmed Aly, Barbier, Gerard, Blondel, Alain, Bonino, Roberto, Chamizo Llatas, Maria, Clark, Allan Geoffrey, Couyoumtzelis, Christian, D'Onofrio, Monica, Demierre, Philippe, Diaz-Gomez, Manuel, Efthymiopoulos, Ilias, Eifert, Till, Ferrere, Didier, Gadomski, Szymon, Gaumer, Olivier, Hakobyan, Hayk, Hamilton, Andrew, Kambara, Hisanori, Keil, Markus, La Marra, Daniel, Lefevre, Régis, Leger, Annie, Liu, Yanwen, Macina-Buono, Daniela, Mangin-Brinet, Mariane, Mazzucato, Federica, Mikulec, Bettina, Moneta, Lorenzo, Morone, Maria Cristina, Orellana, Frédérik, Perrin, Eric, Pohl, Martin, Robichaud-Veronneau, Andrée, Rosselet, Laurent, Sfyrla, Anna, Straessner, Arno, Vu Anh, Tuan, Vuaridel, Bertrand, Wu, Xin, Faculdade de Engenharia, UCL - SST/IRMP - Institut de recherche en mathématique et physique, ATLAS (IHEF, IoP, FNWI), Aad, G, Petrucci, Fabrizio, and Ceradini, Filippo

Subjects
Heavy-ion collisions, Optical alignment systems, Física [Ciências exactas e naturais], ATLAS LHC High Energy Physics, Physics::Instrumentation and Detectors, Ciencias Físicas, 01 natural sciences, High-level trigger, Trigger and data acquisition, Particle identification, Tracking algorithms, Optical fibres, Transition radiation, Drift tubes, CERN, Fluorinert cooling, Jets, Superconducting magnets, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Bunch-crossings, Detectors and Experimental Techniques, Nuclear Experiment, Instrumentation, Mathematical Physics, ATLAS Experiment, Impact parameter measurements, Muons, Resistive-plate chambers, Solenoidal field, Toroidal field, Settore FIS/01 - Fisica Sperimentale, ATLAS, Accordion geometry, Missing transverse energy, Detector control system, Carbon-fibre reinforced plastics, Trigger chambers, LHC, Minimum-bias events, CIENCIAS NATURALES Y EXACTAS, Sampling calorimeters, Precision-tracking chambers, Event filter, Pixel detectors, Accelerator, Longitudinal segmentation, Electrons, ddc:500.2, Calorimetry, Taus, Lateral segmentation, b-tagging, Proton-proton collisions, Physical sciences [Natural sciences], Silicon micro-strip detectors, Bandwidth, Inner detector, Muon spectrometer, Forward detectors, 0103 physical sciences, Cerenkov light, Pile-up, Magnetic field measurements, Hall probes, Charged-particle tracking, Vertex measurement, Time-over-threshold, Radiation-hard electronics, Liquid argon, Scintillator tiles, Electromagnetic and hadronic interactions, Forward calorimetry, Thin-gap chambers, Roman Pots, Zero-degree calorimetry, Processor farm, Leptons, Photons, Vertexing algorithms, 010306 general physics, accelerator, accordion geometry, atlas, bandwidth, bunch-crossings, calorimetry, carbon-fibre reinforced plastics, cerenkov light, cern, charged-particle tracking, detector control system, drift tubes, electromagnetic and hadronic interactions, electrons, event filter, fluorinert cooling, forward calorimetry, forward detectors, hall probes, heavy-ion collisions, high-level trigger, impact parameter measurements, inner detector, jets, lateral segmentation, leptons, lhc, liquid argon, longitudinal segmentation, magnetic field measurements, minimum-bias events, missing transverse energy, muon spectrometer, muons, optical alignment systems, optical fibres, particle identification, photons, pile-up, pixel detectors, precision-tracking chambers, processor farm, proton-proton collisions, radiation-hard electronics, resistive-plate chambers, roman pots, sampling calorimeters, scintillator tiles, silicon micro-strip detectors, solenoidal field, superconducting magnets, taus, thin-gap chambers, time-over-threshold, toroidal field, tracking algorithms, transition radiation, trigger and data acquisition, trigger chambers, vertex measurement, vertexing algorithms, zero-degree calorimetry, 010308 nuclear & particles physics, Astronomía, Física experimental, Física, Experimental physics, Physical sciences, Experimental High Energy Physics, Physics::Accelerator Physics, High Energy Physics::Experiment
Abstract

The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented. Fil: Aad, G.. Aix-Marseille Université; Francia. Centre National de la Recherche Scientifique; Francia Fil: Anduaga, Xabier Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Antonelli, S.. Università di Bologna; Italia Fil: Bendel, M.. Johannes Gutenberg Universitat Mainz; Alemania Fil: Breiler, B.. University of Montreal; Canadá Fil: Castrovillari, F.. Università della Calabria; Italia Fil: Civera, J.V.. Universidad de Valencia; España. Consejo Superior de Investigaciones Científicas; España Fil: Del Prete, T.. Università degli Studi di Pisa; Italia Fil: Dova, Maria Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Duffin, S.. Academy of Sciences of the Czech Republic; República Checa Fil: Fichet, S.. Université Paris Diderot - Paris 7; Francia. Universite Pierre et Marie Curie; Francia Fil: Gaumer, O.. Universidad de Ginebra; Suiza Fil: González Silva, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Goodrick, M. J.. University of Cambridge; Reino Unido Fil: Goujdami, D.. Université Hassan II; Marruecos Fil: Herten, G.. Universität Freiburg; Alemania Fil: Jeremie, A. Université de Savoie; Francia. Centre National de la Recherche Scientifique; Francia Fil: Kieft, G.. University of New Mexico; Estados Unidos Fil: König, S.. Universität Freiburg; Alemania Fil: Kirk, J.. Rutherford Appleton Laboratory. Science and Technology Facilities Council; Reino Unido Fil: Lapin, V.V.. Federal Agency of Atomic Energy; Rusia Fil: LeGeyt, B.C.. University of Pennsylvania; Estados Unidos Fil: Love, J.. Boston University; Estados Unidos Fil: Merola,L.. Seconda Universita Degli Studi Di Napoli; Italia Fil: Miyagawa, P.S.. University of Manchester; Reino Unido Fil: Monticelli, Fernando Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Piegaia, Ricardo Nestor. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina Fil: Plamondon, M.. Université Paris Sud; Francia. Centre National de la Recherche Scientifique; Francia Fil: Raith, B.. Universitat Bonn; Alemania Fil: Romeo, Gaston Leonardo. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Saavedra, A.F.. University of Sydney; Australia Fil: Sanchis Lozano, M.A. Universidad de Valencia; España. Consejo Superior de Investigaciones Científicas; España Fil: Schott, M.. Ludwig Maximilians Universitat; Alemania Fil: Soloviev, I.. Petersburg Nuclear Physics Institute; Rusia Fil: Tripiana, Martin Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina Fil: Zychacek, V.. Czech Technical University in Prague; República Checa

Published
2008
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49. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells

Author

Fruman, D. A., Barbara Bierer, Benes, J. E., Burakoff, S. J., Austen, K. F., and Katz, H. R.

Subjects
Immunology, Immunology and Allergy
Abstract

FK506 and cyclosporin A (CsA) are immunosuppressive agents that inhibit IL-2 production by activated T cells, but only CsA inhibits IgE activation-induced cytokine transcripts in mouse IL-3-dependent, bone marrow-derived mast cells (BMMC). We previously associated the resistance of BMMC to FK506 with a deficiency in the expression of FK506 binding protein (FKBP) 12, a molecule that forms a complex with FK506 capable of inhibiting calcineurin phosphatase activity in vitro. In this report, we establish that FKBP12 mediates FK506 inhibition of both calcineurin phosphatase activity and IgE activation-induced cytokine transcripts in a Kirsten murine sarcoma virus-immortalized mast cell line that is FKBP12 deficient. Overexpression of FKBP12 by transfection enhanced the ability of FK506 to inhibit calcineurin phosphatase activity (IC50 = 2 nM), compared with cells transfected with the expression vector alone (IC50 > 30 nM). The IC50 value for FK506 inhibition of IgE activation-induced transcripts for TNF-alpha decreased from 40 nM in vector control cells to 10 nM in FKBP12 transfectants. Similarly, the IC50 value for inhibition of IL-6 transcripts decreased from > 1000 nM in vector control cells to 35 nM in FKBP12 transfectants. In contrast, activation-elicited release of the secretory granule mediator beta-hexosaminidase was only partially inhibited by FK506 at 1000 nM, regardless of the levels of FKBP12 expressed by the cells. Thus, FKBP12 is the dominant cytosolic protein that mediates FK506 inhibition of TNF-alpha and IL-6 transcripts.

Published
1995
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