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Background. Androgenetic alopecia is the most common type of hair loss in men, but little is known about the etiology of androgenetic alopecia in elderly men and its impact on perceived age. Here we used a population-based twin study of men aged 70+ to assess the magnitude of the genetic component affecting hair loss and to examine the association between baldness and perceived age. Methods. In the fourth wave of The Longitudinal Study of Aging Danish Twins we obtained digital photos of the face and photos of the vertex area of 739 elderly male twins, including 148 intact twin pairs. The degree of baldness and perceived age were assessed in each twin by five and nine nurses, respectively. The heritability of balding was estimated using structural-equation analysis, and it was tested whether baldness was associated with estimations of age. Results. The intrapair correlation of degree of balding was consistently higher for monozygotic than for dizygotic twin pairs regardless of the baldness categorization used, and structural-equation analysis revealed a heritability of 79% (95% confidence interval, 0.40-0.85) for the mean baldness index. The remaining variation could be attributed to nonshared environmental effects. There was only a very weak and statistically nonsignificant association between baldness and overestimation of age. Conclusions. The majority of the variation in baldness in elderly men can be explained by genetic factors, and hair quantity has little impact on perceived age in elderly men.

ABSTRACT Efaluzimab has recently been described as a treatment for alopecia areata. Conflicting reports and studies have spurred discussion as to whether efaluzimab is an effective treatment of alopecia areata. [...]

Byline: Ola. Bakry, Mohamed. Basha, Maather. El Shafiee, Wafaa. Shehata Context: Alopecia areata (AA) is a common form of localized, non-scarring hair loss. The etiopathogenesis of the disease is still [...]

Byline: Virendra. Sehgal, Pullabatla. Prasad, Jangid. Lal Sir, A 10-year-old boy who was studying 5 [sup]th standard in the public sector school reported with progressive thinning of the hair from [...]

Byline: Ulker. Gul, Secil. Soylu, Murat. Demiriz Sir, Psoriasis is a chronic disease having different facets of clinical presentation. In this letter, we report a fairly uncommon presentation of scalp [...]

Byline: Gomathy. Sethuraman, Amit. Malhotra, Vinod. Sharma Sir, Patients with Down syndrome have increased prevalence of common dermatological conditions like folliculitis, atopy and vitiligo, besides having increased incidence of peculiar [...]

Byline: Binod. Khaitan, Rashmi. Mittal, Kaushal. Verma BACKGROUND: Extensive alopecia areata is known to respond to daily oral corticosteroids. To minimize the side effects of daily corticosteroids, oral mini-pulse therapy [...]

Abstract Introduction: Many commonly prescribed prescription drugs such as dopaminergic therapies can cause temporary hair loss. Sertraline is a selective serotonin reuptake inhibitor. Its relative potency for dopamine reuptake inhibition [...]

Abstract Alopecia areata is an organ specific autoimmune disease in which hair is lost in various patterns. Its most extreme form, alopecia universalis, is the total loss of all scalp [...]

Abstract The most commonly reported side effects related to lopinavir/ritonavir are diarrhea, vomiting, headache, nausea, and increased serum triglycerides and cholesterol levels. About 4% of the patients prescribed lopinavir/ritonavir stop [...]

ALOPECIA AREATA CAN BE REFRACTORY TO TOPICAL immunetherapy. In this study, investigators evaluated the efficacy of SADBE (squaric acid dibutylester) topical immunotherapy combined with topical dry ice cryotherapy, carpronium chloride [...]