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12. In-line monitoring of electrolytes and urea during continuous renal replacement therapy

Author

M. Berger, M. Sehlmeyer, F. Sellering, H. Röhrich, T. Perl, H. Mansour, D. Baasner, and S. Zimmermann

Subjects
Technology
Abstract

The individualization of dialysis treatment using a customized dialysate composition usually requires a continuous measurement of electrolytes and urea in blood. The current practices are spot measurements of blood samples either with blood gas analyzers or in the laboratory, involving considerable personnel effort. Furthermore, the measured values are time delayed and not available in a continuous fashion. In this paper we investigate an in-line concept for continuous monitoring of important blood parameters such as sodium, potassium, calcium and urea concentrations in blood serum using ion-selective electrodes. This concept is evaluated in a preclinical study with human packed red blood cells as a test medium over a period of 7 h. It has been shown that the electrolytes can be well monitored. In addition, we present first measurements with ion-sensitive field-effect transistors in a miniaturized sensor assembly. Therefore, new low-cost electronics for such ion-sensitive field-effect transistors have been developed.

Published
2020
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13. Sammelrezension: Neuerscheinungen zu den deutschfranzösischen Kulturbeziehungen

Author

Baasner, Frank, dfi - Deutsch-Französisches Institut, Deutsch-Französisches Institut, Baasner, Frank, In cooperation with, Hoffmann-Martinot, Vincent, In cooperation with, Hüser, Dietmar, In cooperation with, Keller, Eileen, Series editor, Kolboom, Ingo, In cooperation with, Kuon, Peter, In cooperation with, Seidendorf, Stefan, In cooperation with, Stäblein, Ruthard, In cooperation with, Uterwedde, Henrik, In cooperation with, and Deutsch-Französisches Institut, editor

Published
2017
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14. Wolfgang Boeckh (Hg.): 'Den europäischen Gedanken lebendig erhalten…' Wilhelm-Hausenstein-Symposium 2016

Author

Baasner, Frank, dfi - Deutsch-Französisches Institut, Deutsch-Französisches Institut, Baasner, Frank, In cooperation with, Hoffmann-Martinot, Vincent, In cooperation with, Hüser, Dietmar, In cooperation with, Keller, Eileen, Series Editor, Kolboom, Ingo, In cooperation with, Kuon, Peter, In cooperation with, Seidendorf, Stefan, In cooperation with, Stäblein, Ruthard, In cooperation with, Uterwedde, Henrik, In cooperation with, and Deutsch-Französisches Institut, editor

Published
2018
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23. Clinical significance and risk factors for new onset and recurring atrial fibrillation following cardiac surgery - a retrospective data analysis

Author

Hristo Todorov, Inka Janssen, Stefanie Honndorf, Daniela Bause, Antje Gottschalk, Silke Baasner, Thomas Volkert, Valentin Faerber, John F. Stover, Martin Westphal, and Björn Ellger

Subjects
Postoperative atrial fibrillation, CABG, Valve surgery, Inflammation, C-reactive protein, Positive fluid balance, Anesthesiology, RD78.3-87.3
Abstract

Abstract Background Although mortality after cardiac surgery has significantly decreased in the last decade, patients still experience clinically relevant postoperative complications. Among others, atrial fibrillation (AF) is a common consequence of cardiac surgery, which is associated with prolonged hospitalization and increased mortality. Methods We retrospectively analyzed data from patients who underwent coronary artery bypass grafting, valve surgery or a combination of both at the University Hospital Muenster between April 2014 and July 2015. We evaluated the incidence of new onset and intermittent/permanent AF (patients with pre- and postoperative AF). Furthermore, we investigated the impact of postoperative AF on clinical outcomes and evaluated potential risk factors. Results In total, 999 patients were included in the analysis. New onset AF occurred in 24.9% of the patients and the incidence of intermittent/permanent AF was 59.5%. Both types of postoperative AF were associated with prolonged ICU length of stay (median increase approx. 2 days) and duration of mechanical ventilation (median increase 1 h). Additionally, new onset AF patients had a higher rate of dialysis and hospital mortality and more positive fluid balance on the day of surgery and postoperative days 1 and 2. In a multiple logistic regression model, advanced age (odds ratio (OR) = 1.448 per decade increase, p

Published
2017
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24. Ulrike Schröber: Auf dem Weg zur europäischen Völkerverständigung – Die deutsch-französische Annäherung nach dem Zweiten Weltkrieg. Marcel Sturm und Robert Picard de la Vacquerie als oberste französische Militärgeistliche in Deutschland

Author

Baasner, Frank, dfi - Deutsch-Französisches Institut, Deutsch-Französisches Institut, Baasner, Frank, In cooperation with, Hoffmann-Martinot, Vincent, In cooperation with, Hüser, Dietmar, In cooperation with, Keller, Eileen, Series Editor, Kolboom, Ingo, In cooperation with, Kuon, Peter, In cooperation with, Seidendorf, Stefan, In cooperation with, Stäblein, Ruthard, In cooperation with, Uterwedde, Henrik, In cooperation with, and Deutsch-Französisches Institut, editor

Published
2018
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28. Incentives for HIV testing at the workplace in the automotive industry in the Nelson Mandela Bay Municipality: Ethical considerations

Author

Martin Weihs, Anna Meyer-Weitz, and Friederike Baasner-Weihs

Subjects
Medical legislation, K3601-3611, Medicine, Medical philosophy. Medical ethics, R723-726
Abstract

Comprehensive HIV and AIDS workplace programmes made use of substantial lottery incentives in HIV counselling and testing drives to promote HIV testing at four companies in the automotive industry in the Nelson Mandela Bay Municipality. The main aim was to use lottery incentives to increase uptake for HIV testing. This would help to define company HIV prevalence and ensure timely support, care and treatment of employees. In total, 1 324 employees, making up about 90% of the total staff, were tested for HIV in the four companies during wellness testing days. In order to gain an understanding of employees’ experiences of the lotteries as part of the HIV counselling and testing drive, quantitative data were collected among a total of 414 employees, and 17 interviews were conducted in the four companies. In this article, we investigate the issue of whether the lotteries unduly influenced the employees’ participation in workplace HIV testing, and an approach to resolving an identified ethical dilemma is presented. The ethical question as to whether lottery incentives contribute to undue coercion was explored using both a utilitarian and a deontological approach. The analysis concluded that the use of lotteries to encourage HIV testing in the workplaces of the automotive industry in the Nelson Mandela Bay Municipality can be deemed morally acceptable.

Published
2017
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30. Rezension: Brücken bauen. Kulturwissenschaft aus interkultureller und multidisziplinärer Perspektive

Author

Baasner, Frank, dfi - Deutsch-Französisches Institut, Deutsch-Französisches Institut, Baasner, Frank, In cooperation with, Hoffmann-Martinot, Vincent, In cooperation with, Hüser, Dietmar, In cooperation with, Keller, Eileen, Series editor, Kolboom, Ingo, In cooperation with, Kuon, Peter, In cooperation with, Seidendorf, Stefan, In cooperation with, Stäblein, Ruthard, In cooperation with, Uterwedde, Henrik, In cooperation with, and Deutsch-Französisches Institut, editor

Published
2017
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32. FRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours

Author

Seitz, Judith, Bilsland, Alan, Puget, Chloé, Baasner, Ian, Klopfleisch, Robert, and Stein, Torsten

Subjects
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche, RNA Signature, SFRP1, Canine Mammary Tumours, Metastasis
Abstract

Background Canine mammary tumours (CMTs) are the most frequent tumours in intact female dogs and show strong similarities with human breast cancer. In contrast to the human disease there are no standardised diagnostic or prognostic biomarkers available to guide treatment. We recently identified a prognostic 18-gene RNA signature that could stratify human breast cancer patients into groups with significantly different risk of distant metastasis formation. Here, we assessed whether expression patterns of these RNAs were also associated with canine tumour progression. Method A sequential forward feature selection process was performed on a previously published microarray dataset of 27 CMTs with and without lymph node (LN) metastases to identify RNAs with significantly differential expression to identify prognostic genes within the 18-gene signature. Using an independent set of 33 newly identified archival CMTs, we compared expression of the identified prognostic subset on RNA and protein basis using RT-qPCR and immunohistochemistry on FFPE-tissue sections. Results While the 18-gene signature as a whole did not have any prognostic power, a subset of three RNAs: Col13a1, Spock2, and Sfrp1, together completely separated CMTs with and without LN metastasis in the microarray set. However, in the new independent set assessed by RT-qPCR, only the Wnt-antagonist Sfrp1 showed significantly increased mRNA abundance in CMTs without LN metastases on its own (p = 0.013) in logistic regression analysis. This correlated with stronger SFRP1 protein staining intensity of the myoepithelium and/or stroma (p < 0.001). SFRP1 staining, as well as β-catenin membrane staining, was significantly associated with negative LN status (p = 0.010 and 0.014 respectively). However, SFRP1 did not correlate with β-catenin membrane staining (p = 0.14). Conclusion The study identified SFRP1 as a potential biomarker for metastasis formation in CMTs, but lack of SFRP1 was not associated with reduced membrane-localisation of β-catenin in CMTs.

Published
2023

33. Bildungsdiskussionen in Frankreich

Author

Baasner, Frank, Asholt, Wolfgang, editor, Baasner, Frank, editor, Bock, Hans Manfred, editor, Hoffmann-Martinot, Vincent, editor, Hüser, Dietmar, editor, Kolboom, Ingo, editor, Kuon, Peter, editor, Picht, Robert, editor, Uterwedde, Henrik, editor, and Vogel, Wolfram, editor

Published
2006
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35. Deutschsprachige Literatur zu Frankreich: Ausgewählte Neuerscheinungen 2002/2003

Author

Albertin, Lothar, Asholt, Wolfgang, Baasner, Frank, Bock, Hans Manfred, Christadler, Marieluise, Kimmel, Adolf, Kolboom, Ingo, Picht, Robert, Uterwedde, Henrik, Albertin, Lothar, editor, Asholt, Wolfgang, editor, Baasner, Frank, editor, Bock, Hans Manfred, editor, Christadler, Marieluise, editor, Kimmel, Adolf, editor, Kolboom, Ingo, editor, Picht, Robert, editor, and Uterwedde, Henrik, editor

Published
2004
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36. Chronik 2002–2003

Author

Albertin, Lothar, Asholt, Wolfgang, Baasner, Frank, Bock, Hans Manfred, Christadler, Marieluise, Kimmel, Adolf, Kolboom, Ingo, Picht, Robert, Uterwedde, Henrik, Albertin, Lothar, editor, Asholt, Wolfgang, editor, Baasner, Frank, editor, Bock, Hans Manfred, editor, Christadler, Marieluise, editor, Kimmel, Adolf, editor, Kolboom, Ingo, editor, Picht, Robert, editor, and Uterwedde, Henrik, editor

Published
2004
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38. W21 Marlboro Man Many Lab Replication

Author

Langkamp, Thomas, Gahrmann, Mario, Thiele, Johanna, Sylvia, Isele, Rebecca, Barckhan, Florian, Baasner, Julia, Turtschan, Nele, Gumbel, Meike, Ramez, Dunja, Weddigen, Lennart, P., Valentina, Sprengel, Lina, Schmahl, Felix, Lichius, Annalena, Fabian, Hanna, Ahrens, Merle, Larsen, Britt-Marie, Üzüm, Sidar, Sirin, Ballauff, Lara, Nathalie, Zimmermann, Laura, Könekamp, Leonie, Stamer, Moritz, Wilmanns, Johannes, Brumm, Marie, Remer, Jenny, Bröcker, Larissa, Karschny, Sina, Dumke, Frida, Trabinski, Luisa, and Rösler, Emilia

Subjects
replication, ComputingMilieux_COMPUTERSANDEDUCATION, many lab, teaching scientific methods
Abstract

My Master Students replicating the "Marlboro Man do not cry"-Study in a many lab style semester-project

Published
2022
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39. Marlboro Man Many Lab (Team: Die Galaktischen Erkos)

Author

Turtschan, Nele, Gahrmann, Mario, and Baasner, Julia

Subjects
replication, Medicine and Health Sciences, Business, many lab, Social and Behavioral Sciences, teaching scientific methods
Abstract

Many Labs (Team: Die Galaktischen Erkos, bestehend aus Julia Baasner, Mario Gehrmann und Nele Turtschan) - Eine Replikationsstudie über die geschlechtsspezifische Wahrnehmung von Männern, die psychiatrische Versorgung in Anspruch nehmen, basierend auf Li & Gal (2021). Expliziter Hinweis: Diese Studie ist eine Replikationsstudie! Originalstudie: http://dx.doi.org/10.1037/xap0000360

Published
2022
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40. Vorwort

Author

Baasner, Frank, Albertin, Lothar, editor, Asholt, Wolfgang, editor, Baasner, Frank, editor, Bock, Hans Manfred, editor, Hoffmann-Martinot, Vincent, editor, Hüser, Dietmar, editor, Kuon, Peter, editor, Kolboom, Ingo, editor, Picht, Robert, editor, Uterwedde, Henrik, editor, and Vogel, Wolfram, editor

Published
2005
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50. Fritz Schenk und die Gründung des Deutsch-Französischen Instituts

Author

Baasner, Frank

Subjects
920 Biografien, Genealogie, Insignien, 060 Allgemeine Organisationen, Museumswissenschaft
Abstract

Fritz Schenk (1906–1985) brachte aufgrund seiner Biographie eine enge Vertrautheit mit Deutschland und Frankreich mit. Als Sohn deutscher Eltern im Grenzort Nouvel-Avricourt in Lothringen geboren, ging er zusammen mit jungen Franzosen zur Schule. Am Ende des Ersten Weltkriegs zog die Familie 1919 nach Kirchheim unter Teck, woher seine Mutter stammte. Dort legte Schenk 1925 das Abitur ab. Es folgten Studienaufenthalte in Tübingen, Berlin, Nancy (zwei Monate) und Paris (ein Semester). Nach dem Studium der Romanistik und Geschichte promovierte er 1932 in Tübingen zu einem zeithistorischen Thema.

Published
2022
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