Search

Your search keyword '"Angelo Amato Vicenzo de Paola"' showing total 19 results
Start Over Author "Angelo Amato Vicenzo de Paola" Publication Year Range Last 50 years
19 results on '"Angelo Amato Vicenzo de Paola"'

1. Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

Author

George Ntaios, Menno V. Huisman, Hans-Christoph Diener, Jonathan L. Halperin, Christine Teutsch, Sabrina Marler, Venkatesh K. Gurusamy, Milla Thompson, Gregory Y.H. Lip, Brian Olshansky, Dzifa Wosornu Abban, Nasser Abdul, Atilio Marcelo Abud, Fran Adams, Srinivas Addala, Pedro Adragão, Walter Ageno, Rajesh Aggarwal, Sergio Agosti, Piergiuseppe Agostoni, Francisco Aguilar, Julio Aguilar Linares, Luis Aguinaga, Jameel Ahmed, Allessandro Aiello, Paul Ainsworth, Jorge Roberto Aiub, Raed Al-Dallow, Lisa Alderson, Jorge Antonio Aldrete Velasco, Dimitrios Alexopoulos, Fernando Alfonso Manterola, Pareed Aliyar, David Alonso, Fernando Augusto Alves da Costa, José Amado, Walid Amara, Mathieu Amelot, Nima Amjadi, Fabrizio Ammirati, Marianna Andrade, Nabil Andrawis, Giorgio Annoni, Gerardo Ansalone, M.Kevin Ariani, Juan Carlos Arias, Sébastien Armero, Chander Arora, Muhammad Shakil Aslam, M. Asselman, Philippe Audouin, Charles Augenbraun, S. Aydin, Ivaneta Ayryanova, Emad Aziz, Luciano Marcelo Backes, E. Badings, Ermentina Bagni, Seth H. Baker, Richard Bala, Antonio Baldi, Shigenobu Bando, Subhash Banerjee, Alan Bank, Gonzalo Barón Esquivias, Craig Barr, Maria Bartlett, Vanja Basic Kes, Giovanni Baula, Steffen Behrens, Alan Bell, Raffaella Benedetti, Juan Benezet Mazuecos, Bouziane Benhalima, Jutta Bergler-Klein, Jean-Baptiste Berneau, Richard A. Bernstein, Percy Berrospi, Sergio Berti, Andrea Berz, Elizabeth Best, Paulo Bettencourt, Robert Betzu, Ravi Bhagwat, Luna Bhatta, Francesco Biscione, Giovanni BISIGNANI, Toby Black, Michael J. Bloch, Stephen Bloom, Edwin Blumberg, Mario Bo, Ellen Bøhmer, Andreas Bollmann, Maria Grazia Bongiorni, Giuseppe Boriani, D.J. Boswijk, Jochen Bott, Edo Bottacchi, Marica Bracic Kalan, Drew Bradman, Donald Brautigam, Nicolas Breton, P.J.A.M. Brouwers, Kevin Browne, Jordi Bruguera Cortada, A. Bruni, Claude Brunschwig, Hervé Buathier, Aurélie Buhl, John Bullinga, Jose Walter Cabrera, Alberto Caccavo, Shanglang Cai, Sarah Caine, Leonardo Calò, Valeria Calvi, Mauricio Camarillo Sánchez, Rui Candeias, Vincenzo Capuano, Alessandro Capucci, Ronald Caputo, Tatiana Cárdenas Rizo, Francisco Cardona, Francisco Carlos da Costa Darrieux, Yan Carlos Duarte Vera, Antonio Carolei, Susana Carreño, Paula Carvalho, Susanna Cary, Gavino Casu, Claudio Cavallini, Guillaume Cayla, Aldo Celentano, Tae-Joon Cha, Kwang Soo Cha, Jei Keon Chae, Kathrine Chalamidas, Krishnan Challappa, Sunil Prakash Chand, Harinath Chandrashekar, Ludovic Chartier, Kausik Chatterjee, Carlos Antero Chavez Ayala, Aamir Cheema, Amjad Cheema, Lin Chen, Shih-Ann Chen, Jyh Hong Chen, Fu-Tien Chiang, Francesco Chiarella, Lin Chih-Chan, Yong Keun Cho, Jong-Il Choi, Dong Ju Choi, Guy Chouinard, Danny Hoi-Fan Chow, Dimitrios Chrysos, Galina Chumakova, Eduardo Julián José Roberto Chuquiure Valenzuela, Nicoleta Cindea Nica, David J. Cislowski, Anthony Clay, Piers Clifford, Andrew Cohen, Michael Cohen, Serge Cohen, Furio Colivicchi, Ronan Collins, Paolo Colonna, Steve Compton, Derek Connolly, Alberto Conti, Gabriel Contreras Buenostro, Gregg Coodley, Martin Cooper, Julian Coronel, Giovanni Corso, Juan Cosín Sales, Yves Cottin, John Covalesky, Aurel Cracan, Filippo Crea, Peter Crean, James Crenshaw, Tina Cullen, Harald Darius, Patrick Dary, Olivier Dascotte, Ira Dauber, Vicente Davalos, Ruth Davies, Gershan Davis, Jean-Marc Davy, Mark Dayer, Marzia De Biasio, Silvana De Bonis, Raffaele De Caterina, Teresiano De Franceschi, J.R. de Groot, José De Horta, Axel De La Briolle, Gilberto de la Pena Topete, Angelo Amato Vicenzo de Paola, Weimar de Souza, A. de Veer, Luc De Wolf, Eric Decoulx, Sasalu Deepak, Pascal Defaye, Freddy Del-Carpio Munoz, Diana Delic Brkljacic, N. Joseph Deumite, Silvia Di Legge, Igor Diemberger, Denise Dietz, Pedro Dionísio, Qiang Dong, Fabio Rossi dos Santos, Elena Dotcheva, Rami Doukky, Anthony D'Souza, Simon Dubrey, Xavier Ducrocq, Dmitry Dupljakov, Mauricio Duque, Dipankar Dutta, Nathalie Duvilla, A. Duygun, Rainer Dziewas, Charles B. Eaton, William Eaves, L.A. Ebels-Tuinbeek, Clifford Ehrlich, Sabine Eichinger-Hasenauer, Steven J. Eisenberg, Adnan El Jabali, Mahfouz El Shahawy, Mauro Esteves Hernandes, Ana Etxeberria Izal, Rudolph Evonich, III, Oksana Evseeva, Andrey Ezhov, Raed Fahmy, Quan Fang, Ramin Farsad, Laurent Fauchier, Stefano Favale, Maxime Fayard, Jose Luis Fedele, Francesco Fedele, Olga Fedorishina, Steven R. Fera, Luis Gustavo Gomes Ferreira, Jorge Ferreira, Claudio Ferri, Anna Ferrier, Hugo Ferro, Alexandra Finsen, Brian First, Stuart Fischer, Catarina Fonseca, Luísa Fonseca Almeida, Steven Forman, Brad Frandsen, William French, Keith Friedman, Athena Friese, Ana Gabriela Fruntelata, Shigeru Fujii, Stefano Fumagalli, Marta Fundamenski, Yutaka Furukawa, Matthias Gabelmann, Nashwa Gabra, Niels Gadsbøll, Michel Galinier, Anders Gammelgaard, Priya Ganeshkumar, Christopher Gans, Antonio Garcia Quintana, Olivier Gartenlaub, Achille Gaspardone, Conrad Genz, Frédéric Georger, Jean-Louis Georges, Steven Georgeson, Evaldas Giedrimas, Mariusz Gierba, Ignacio Gil Ortega, Eve Gillespie, Alberto Giniger, Michael C. Giudici, Alexandros Gkotsis, Taya V. Glotzer, Joachim Gmehling, Jacek Gniot, Peter Goethals, Seth Goldbarg, Ronald Goldberg, Britta Goldmann, Sergey Golitsyn, Silvia Gómez, Juan Gomez Mesa, Vicente Bertomeu Gonzalez, Jesus Antonio Gonzalez Hermosillo, Víctor Manuel González López, Hervé Gorka, Charles Gornick, Diana Gorog, Venkat Gottipaty, Pascal Goube, Ioannis Goudevenos, Brett Graham, G. Stephen Greer, Uwe Gremmler, Paul G. Grena, Martin Grond, Edoardo Gronda, Gerian Grönefeld, Xiang Gu, Ivett Guadalupe Torres Torres, Gabriele Guardigli, Carolina Guevara, Alexandre Guignier, Michele Gulizia, Michael Gumbley, Albrecht Günther, Andrew Ha, Georgios Hahalis, Joseph Hakas, Christian Hall, Bing Han, Seongwook Han, Joe Hargrove, David Hargroves, Kenneth B. Harris, Tetsuya Haruna, Emil Hayek, Jeff Healey, Steven Hearne, Michael Heffernan, Geir Heggelund, J.A. Heijmeriks, Maarten Hemels, I. Hendriks, Sam Henein, Sung-Ho Her, Paul Hermany, Jorge Eduardo Hernández Del Río, Yorihiko Higashino, Michael Hill, Tetsuo Hisadome, Eiji Hishida, Etienne Hoffer, Matthew Hoghton, Kui Hong, Suk keun Hong, Stevie Horbach, Masataka Horiuchi, Yinglong Hou, Jeff Hsing, Chi-Hung Huang, David Huckins, kathy Hughes, A. Huizinga, E.L. Hulsman, Kuo-Chun Hung, Gyo-Seung Hwang, Margaret Ikpoh, Davide Imberti, Hüseyin Ince, Ciro Indolfi, Shujiro Inoue, Didier Irles, Harukazu Iseki, C. Noah Israel, Bruce Iteld, Venkat Iyer, Ewart Jackson-Voyzey, Naseem Jaffrani, Frank Jäger, Martin James, Sung-Won Jang, Nicolas Jaramillo, Nabil Jarmukli, Robert J. Jeanfreau, Ronald D. Jenkins, Carlos Jerjes Sánchez, Javier Jimenez, Robert Jobe, Tomas Joen-Jakobsen, Nicholas Jones, Jose Carlos Moura Jorge, Bernard Jouve, Byung Chun Jung, Kyung Tae Jung, Werner Jung, Mikhail Kachkovskiy, Krystallenia Kafkala, Larisa Kalinina, Bernd Kallmünzer, Farzan Kamali, Takehiro Kamo, Priit Kampus, Hisham Kashou, Andreas Kastrup, Apostolos Katsivas, Elizabeth Kaufman, Kazuya Kawai, Kenji Kawajiri, John F. Kazmierski, P. Keeling, José Francisco Kerr Saraiva, Galina Ketova, AJIT Singh Khaira, Aleksey Khripun, Doo-Il Kim, Young Hoon Kim, Nam Ho Kim, Dae Kyeong Kim, Jeong Su Kim, June Soo Kim, Ki Seok Kim, Jin bae Kim, Elena Kinova, Alexander Klein, James J. Kmetzo, G. Larsen Kneller, Aleksandar Knezevic, Su Mei Angela Koh, Shunichi Koide, Anastasios Kollias, J.A. Kooistra, Jay Koons, Martin Koschutnik, William J. Kostis, Dragan Kovacic, Jacek Kowalczyk, Natalya Koziolova, Peter Kraft, Johannes A. Kragten, Mori Krantz, Lars Krause, B.J. Krenning, F. Krikke, Z. Kromhout, Waldemar Krysiak, Priya Kumar, Thomas Kümler, Malte Kuniss, Jen-Yuan Kuo, Achim Küppers, Karla Kurrelmeyer, Choong Hwan Kwak, Bénédicte Laboulle, Arthur Labovitz, Wen Ter Lai, Andy Lam, Yat Yin Lam, Fernando Lanas Zanetti, Charles Landau, Giancarlo Landini, Estêvão Lanna Figueiredo, Torben Larsen, Karine Lavandier, Jessica LeBlanc, Moon Hyoung Lee, Chang-Hoon Lee, John Lehman, Ana Leitão, Nicolas Lellouche, Malgorzata Lelonek, Radoslaw Lenarczyk, T. Lenderink, Salvador León González, Peter Leong-Sit, Matthias Leschke, Nicolas Ley, Zhanquan Li, Xiaodong Li, Weihua Li, Xiaoming Li, Christhoh Lichy, Ira Lieber, Ramon Horacio Limon Rodriguez, Hailong Lin, Feng Liu, Hengliang Liu, Guillermo Llamas Esperon, Nassip Llerena Navarro, Eric Lo, Sergiy Lokshyn, Amador López, José Luís López-Sendón, Adalberto Menezes Lorga Filho, Richard S. Lorraine, Carlos Alberto Luengas, Robert Luke, Ming Luo, Steven Lupovitch, Philippe Lyrer, Changsheng Ma, Genshan Ma, Irene Madariaga, Koji Maeno, Dominique Magnin, Gustavo Maid, Sumeet K. Mainigi, Konstantinos Makaritsis, Rohit Malhotra, Rickey Manning, Athanasios Manolis, Helard Andres Manrique Hurtado, Ioannis Mantas, Fernando Manzur Jattin, Vicky Maqueda, Niccolo Marchionni, Francisco Marin Ortuno, Antonio Martín Santana, Jorge Martinez, Petra Maskova, Norberto Matadamas Hernandez, Katsuhiro Matsuda, Tillmann Maurer, Ciro Mauro, Erik May, Nolan Mayer, John McClure, Terry McCormack, William McGarity, Hugh McIntyre, Brent McLaurin, Feliz Alvaro Medina Palomino, Francesco Melandri, Hiroshi Meno, Dhananjai Menzies, Marco Mercader, Christian Meyer, Beat j. Meyer, Jacek Miarka, Frank Mibach, Dominik Michalski, Patrik Michel, Rami Mihail Chreih, Ghiath Mikdadi, Milan Mikus, Davor Milicic, Constantin Militaru, Sedi Minaie, Bogdan Minescu, Iveta Mintale, Tristan Mirault, Michael J. Mirro, Dinesh Mistry, Nicoleta Violeta Miu, Naomasa Miyamoto, Tiziano Moccetti, Akber Mohammed, Azlisham Mohd Nor, Michael Mollerus, Giulio Molon, Sergio Mondillo, Patrícia Moniz, Lluis Mont, Vicente Montagud, Oscar Montaña, Cristina Monti, Luciano Moretti, Kiyoo Mori, Andrew Moriarty, Jacek Morka, Luigi Moschini, Nikitas Moschos, Andreas Mügge, Thomas J. Mulhearn, Carmen Muresan, Michela Muriago, Wlodzimierz Musial, Carl W. Musser, Francesco Musumeci, Thuraia Nageh, Hidemitsu Nakagawa, Yuichiro Nakamura, Toru Nakayama, Gi-Byoung Nam, Michele Nanna, Indira Natarajan, Hemal M. Nayak, Stefan Naydenov, Jurica Nazli, Alexandru Cristian Nechita, Libor Nechvatal, Sandra Adela Negron, James Neiman, Fernando Carvalho Neuenschwander, David Neves, Anna Neykova, Ricardo Nicolás Miguel, George Nijmeh, Alexey Nizov, Rodrigo Noronha Campos, Janko Nossan, Tatiana Novikova, Ewa Nowalany-Kozielska, Emmanuel Nsah, Juan Carlos Nunez Fragoso, Svetlana Nurgalieva, Dieter Nuyens, Ole Nyvad, Manuel Odin de Los Rios Ibarra, Philip O'Donnell, Martin O'Donnell, Seil Oh, Yong Seog Oh, Dongjin Oh, Gilles O'Hara, Kostas Oikonomou, Claudia Olivares, Richard Oliver, Rafael Olvera Ruiz, Christoforos Olympios, Anna omaszuk-Kazberuk, Joaquín Osca Asensi, eena Padayattil jose, Francisco Gerardo Padilla Padilla, Victoria Padilla Rios, Giuseppe Pajes, A. Shekhar Pandey, Gaetano Paparella, F. Paris, Hyung Wook Park, Jong Sung Park, Fragkiskos Parthenakis, Enrico Passamonti, Rajesh J. Patel, Jaydutt Patel, Mehool Patel, Janice Patrick, Ricardo Pavón Jimenez, Analía Paz, Vittorio Pengo, William Pentz, Beatriz Pérez, Alma Minerva Pérez Ríos, Alejandro Pérez-Cabezas, Richard Perlman, Viktor Persic, Francesco Perticone, Terri K. Peters, Sanjiv Petkar, Luis Felipe Pezo, Christian Pflücke, David N. Pham, Roland T. Phillips, Stephen Phlaum, Denis Pieters, Julien Pineau, Arnold Pinter, Fausto Pinto, R. Pisters, Nediljko Pivac, Darko Pocanic, Cristian Podoleanu, Alessandro Politano, Zdravka Poljakovic, Stewart Pollock, Jose Polo Garcéa, Holger Poppert, Maurizio Porcu, Antonio Pose Reino, Neeraj Prasad, Dalton Bertolim Précoma, Alessandro Prelle, John Prodafikas, Konstantin Protasov, Maurice Pye, Zhaohui Qiu, Jean-Michel Quedillac, Dimitar Raev, Carlos Antonio Raffo Grado, Sidiqullah Rahimi, Arturo Raisaro, Bhola Rama, Ricardo Ramos, Maria Ranieri, Nuno Raposo, Eric Rashba, Ursula Rauch-Kroehnert, Ramakota Reddy, Giulia Renda, Shabbir Reza, Luigi Ria, Dimitrios Richter, Hans Rickli, Werner Rieker, Tomas Ripolil Vera, Luiz Eduardo Ritt, Douglas Roberts, Ignacio Rodriguez Briones, Aldo Edwin Rodriguez Escudero, Carlos Rodríguez Pascual, Mark Roman, Francesco Romeo, E. Ronner, Jean-Francois Roux, Nadezda Rozkova, Miroslav Rubacek, Frank Rubalcava, Andrea M. Russo, Matthieu Pierre Rutgers, Karin Rybak, Samir Said, Tamotsu Sakamoto, Abraham Salacata, Adrien Salem, Rafael Salguero Bodes, Marco A. Saltzman, Alessandro Salvioni, Gregorio Sanchez Vallejo, Marcelo Sanmartín Fernández, Wladmir Faustino Saporito, Kesari Sarikonda, Taishi Sasaoka, Hamdi Sati, Irina Savelieva, Pierre-Jean Scala, Peter Schellinger, Carlos Scherr, Lisa Schmitz, Karl-Heinz Schmitz, Bettina Schmitz, Teresa Schnabel, Steffen Schnupp, Peter Schoeniger, Norbert Schön, Peter Schwimmbeck, Clare Seamark, Greg Searles, Karl-Heinz Seidl, Barry Seidman, Jaroslaw Sek, Lakshmanan Sekaran, Carlo SERRATI, Neerav Shah, Vinay Shah, Anil Shah, Shujahat Shah, Vijay Kumar Sharma, Louise Shaw, Khalid H. Sheikh, Naruhito Shimizu, Hideki Shimomura, Dong-Gu Shin, Eun-Seok Shin, Junya Shite, Gerolamo Sibilio, Frank Silver, Iveta Sime, Tim A. Simmers, Narendra Singh, Peter Siostrzonek, Didier Smadja, David W. Smith, Marcelo Snitman, Dario Sobral Filho, Hassan Soda, Carl Sofley, Adam Sokal, Yannie Soo Oi Yan, Rodolfo Sotolongo, Olga Ferreira de Souza, Jon Arne Sparby, Jindrich Spinar, David Sprigings, Alex C. Spyropoulos, Dimitrios Stakos, Clemens Steinwender, George Stergiou, Ian Stiell, Marcus Stoddard, Anastas Stoikov, Witold Streb, Ioannis Styliadis, Guohai Su, Xi Su, Wanda Sudnik, Kai Sukles, Xiaofei Sun, H. Swart, Janko Szavits-Nossan, Jens Taggeselle, Yuichiro Takagi, Amrit Pal Singh Takhar, Angelika Tamm, Katsumi Tanaka, Tanyanan Tanawuttiwat, Sherman Tang, Aylmer Tang, Giovanni Tarsi, Tiziana Tassinari, Ashis Tayal, Muzahir Tayebjee, J.M. ten Berg, Dan Tesloianu, Salem H.K. The, Dierk Thomas, Serge Timsit, Tetsuya Tobaru, Andrzej R. Tomasik, Mikhail Torosoff, Emmanuel Touze, Elina Trendafilova, W. Kevin Tsai, Hung Fat Tse, Hiroshi Tsutsui, Tian Ming Tu, Ype Tuininga, Minang Turakhia, Samir Turk, Wayne Tcurner, Arnljot Tveit, Richard Tytus, C. Valadão, P.F.M.M. van Bergen, Philippe van de Borne, B.J. van den Berg, C. van der Zwaan, M. Van Eck, Peter Vanacker, Dimo Vasilev, Vasileios Vasilikos, Maxim Vasilyev, Srikar Veerareddy, Mario Vega Miño, Asok Venkataraman, Paolo Verdecchia, Francesco Versaci, Ernst Günter Vester, Hubert Vial, Jason Victory, Alejandro Villamil, Marc Vincent, Anthony Vlastaris, Jürgen vom Dahl, Kishor Vora, Robert B. Vranian, Paul Wakefield, Ningfu Wang, Mingsheng Wang, Xinhua Wang, Feng Wang, Tian Wang, Alberta L. Warner, Kouki Watanabe, Jeanne Wei, Christian Weimar, Stanislav Weiner, Renate Weinrich, Ming-Shien Wen, Marcus Wiemer, Preben Wiggers, Andreas Wilke, David Williams, Marcus L. Williams, Bernhard Witzenbichler, Brian Wong, Ka Sing Lawrence Wong, Beata Wozakowska-Kaplon, Shulin Wu, Richard C. Wu, Silke Wunderlich, Nell Wyatt, John (Jack) Wylie, Yong Xu, Xiangdong Xu, Hiroki Yamanoue, Takeshi Yamashita, Ping Yen Bryan Yan, Tianlun Yang, Jing Yao, Kuo-Ho Yeh, Wei Hsian Yin, Yoto Yotov, Ralf Zahn, Stuart Zarich, Sergei Zenin, Elisabeth Louise Zeuthen, Huanyi Zhang, Donghui Zhang, Xingwei Zhang, Ping Zhang, Jun Zhang, Shui Ping Zhao, Yujie Zhao, Zhichen Zhao, Yang Zheng, Jing Zhou, Sergio Zimmermann, Andrea Zini, Steven Zizzo, Wenxia Zong, and L Steven Zukerman

Subjects
SAMe-TT2R2, atrial fibrillation, non-vitamin-K antagonist oral anticoagulants, vitamin-K-antagonist oral anticoagulants, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007.

Published
2021
Full Text
View/download PDF

2. Abordagem da fibrilaçao atrial na emergência: controle do ritmo ou da frequência?

Author

Cristiano de Oliveira Dietrich, Claudio Cirenza, Guilherme Drummond Fenelon Costa, and Angelo Amato Vicenzo de Paola

Subjects
Fibrilaçao Atrial, Cardioversao Elétrica, Arritmias Cardíacas, Anticoagulaçao, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

A fibrilaçao atrial caracteriza-se por desorganizaçao da atividade elétrica e da contraçao atrial. Clinicamente, está relacionada com aumento de Acidente Vascular Cerebral (AVC) e da mortalidade cardiovascular. Frequentemente é responsável por levar à emergência pacientes cujo manejo baseia-se no controle direto da arritmia e na prevençao de eventos tromboembólicos. Entretanto, existe controvérsia na escolha entre o controle do ritmo ou da frequência cardíaca para o tratamento desta modalidade de arritmia no serviço de emergência.

Published
2013

3. Ablaçao por Radiofreqüência

Author

Maria Zildany Pinheiro TAVORA and Angelo Amato Vicenzo DE PAOLA

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
1997

4. Ablaçao por Radiofreqüência

Author

Henrique Horta VELOSO and Angelo Amato Vicenzo de PAOLA

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
1997

5. The Changing Landscape for Stroke Prevention in AF

Author

Mercedes Samson, Siegfried Frickel, Hirosi Meno, Niels Gadsbøll, Sébastien Prévôt, Sorin Alexandru Antonescu, Xiaodong Li, Tetsuya Haruna, Zicheng Li, Catarina Fonseca, Ralf Zahn, Shahid Aziz, Takashi Tsutsui, Galal Kerfes, Elisabeth Louise Zeuthen, Lluís Mont, Angelika Tamm, Bogdan Minescu, Eric Lo, Gerardo Ansalone, Malcolm Foster, Tristan Mirault, Nabil Andrawis, Apostolos Katsivas, Imad Kreidieh, Juliano Novaes Cardoso, Margaret Ikpoh, Dimitar Raev, Said Chaaban, Dan Tesloianu, Philippe Loiselet, Joachim Gmehling, Joseph Hakas, Steven Forman, Ernst Günter Vester, Bettina Schmitz, Hassan El-Sayed, Hiroshi Tsutsui, Salvatore Pirelli, Jens Taggeselle, Arnljot Tveit, David Smith, Manuel De Los Rios Ibarra, Rafael Salguero, Jindrich Spinar, Vanja Bašić Kes, Jose Walter Cabrera Honorio, Adrien Salem, Gavino Casu, Jean Michel Quedillac, Ana Fruntelata, Peter Siostrzonek, Dmitry Napalkov, Luthando Adams, Valeria Calvi, Jeff S. Healey, Magnus Forsgren, Larisa Kalinina, Ratika Parkash, P. F.M.M. Bergen van, Carmen Manuela Muresan, H. Gorka, Andreas Mügge, Gustavo Maid, Serge Yvorra, Alexander Paraschos, Bernhard Witzenbichler, Viktor Peršić, Jeong Su Kim, Dong Jin Oh, Yutaka Furukawa, Steve Compton, Ravikiran Korabathina, Tammam Al-Joundi, Muzahir H. Tayebjee, Robert Betzu, David J. Cislowski, Alon Steinberg, Carisi Anne Polanczyk, Sanjiv Petkar, Andy Lam, Mingsheng Wang, Galina Ivanchura, Ruediger Seebass, Thomas Guarnieri, Seth H. Baker, Paula Carvalho, Brian First, Konstantinos Makaritsis, Alex C. Spyropoulos, Mohiburrahman Sirajuddin, Richard Bala, David Goldscher, G. Larsen Kneller, Ki Seok Kim, Sherman Tang, Venkat Iyer, Payman Sattar, Yamile Porro, Gregory Y.H. Lip, Christa Raters, Olivier Gartenlaub, Elizaveta Panchenko, Niccolo' Marcionni, Ole Nyvad, Sibel Zehra Aydin, Kenji Kawajiri, Dipankar Dutta, Gabriel Contreras Buenostro, Shaival Kapadia, Harry J.G.M. Crijns, Miroslav Rubacek, Myriam Brunehaut, Igor Diemberger, Kyle Rickner, Katsumi Tanaka, Moon Hyoung Lee, Pamela Nerheim, Jose Carlos Moura Jorge, Michael Gumbley, Katie Randall, Francesco Melandri, Sunil Chand, Harukazu Iseki, Thalie Traissac, Ningfu Wang, Ghiath Mikdadi, Peter D. Schellinger, Andrew M. Rubin, Conrad Genz, Karl Heinz Seidl, Maurice Pye, Giorgio Annoni, Adalberto Menezes Lorga Filho, William H. Pentz, Lisa Schmitz, Gary Miller, Didier Smadja, Elena Khludeeva, David Hargroves, Hans-Christoph Diener, Tiziano Moccetti, Azlisham Mohd Nor, Kai Koenig, F. A. Rooyer, Kiyoo Mori, Carlos Gonzalez Juanatey, Jan Beyer-Westendorf, Charles Landau, Steven B Eisenberg, Hugh F. McIntyre, Emilio Gonzalez Cocina, Erik May, Gyo-Seung Hwang, Alberto Giniger, Karl-Heinz Kuck, Yan Carlos Duarte Vera, Vladimir Gorbunov, Priya Nair, Shih Ann Chen, Beat J. Meyer, Donghui Zhang, Feng Wang, Richard J.H. Smith, Michele Massimo Gulizia, Darko Pocanic, Abul Azim, Jose Maria Lobos, Patrick Leprince, Peter Vanacker, Marica Bracic Kalan, James Crenshaw, Ewa Nowalany-Kozielska, Ayham Al-Zoebi, Eiji Hishida, Louis Essandoh, Younghoon Kim, Yanmin Yang, Dhiraj Gupta, Fausto J. Pinto, Arnold Pinter, Stanley Koch, Luis Felipe Pezo, Dzifa Wosornu Abban, Martin S. Green, Chrystalenia Kafkala, Zhitao Liu, Jose Luis Llisterri, Su Mei Angela Koh, Lin Chih-Chan, Ruth Davies, Ursula Rauch-Kroehnert, Julio Tallet, Juan Benezet-Mazuecos, Andreas Kastrup, Rohit Malhotra, Serge Timsit, Thierry Frappé, Kostas Oikonomou, Ameer Kabour, Kishor Vora, Douglas Roberts, Carlos Scherr, Pedro Dionísio, Nicoleta Violeta Miu, Eve Gillespie, Petr Povolny, F.R. Grondin, Philippe Lyrer, Raymond Fisher, Philip O'Donnell, Nima Amjadi, Juan Vazquez, Lynn Corbett, Patrick Peters, Jing Zhou, Thomas Kümler, Danny H.K. Wong, Evaldas Giedrimas, William McGarity, Frank L. Silver, Emmanuel Touzé, Ana Leitão, Suk keun Hong, Marwan Salfity, Constantin Militaru, S T Matskeplishvili, Johannes A. Kragten, Sam Henein, Anthony D'Souza, B. J. Krenning, Francesco Chiarella, Rene Casanova, Stephan Willems, Yong Keun Cho, Tae Joon Cha, Stewart Pollock, Rajendra Moodley, Rosa Ysabel Cotrina Pereyra, Volker Laske, Zhanquan Li, Kenneth B. Harris, Johnny Dy, Gabriele Guardigli, Hisham Kashou, Norberto Matadamas Hernandez, Zdravka Poljaković, E. Decoulx, Paul Wakefield, Sung Ho Her, Fatma Qaddoura, Giuseppe Boriani, Younus Ismail, Franz Goss, Shigeru Fujii, J. R. Groot de, Ming Shien Wen, Rui Candeias, Thomas Rebane, Juan Carlos Arias, Robert Jobe, Nicolas Ley, Taishi Sasaoka, Luigi Ria, Jonathan Banayan, Paul McLaughlin, Sergei Zenin, Luis E. Martinez, Thuraia Nageh, Fabrizio Ammirati, M. E.W. Hemels, Yutaka Shimizu, Elina Trendafilova, Maxime Fayard, Randeep Suneja, Attilia Maria Pizzini, Mark B. Abelson, Rabih R. Azar, Jian Zhou, Valerie Bockisch, Martin Koschutnik, James Hitchcock, Vlad Ciobotaru, Didier Irles, Patrik Michel, Witold Streb, John F. Corrigan, Ajit Singh Khaira, Marco Antônio Mota Gomes, Richard Tytus, Christian Hall, Antonius Ziekenhuis, Catherine Mallecourt, David J. Williams, Doo Il Kim, Brian Gordon, Salvatore Novo, Soufian Al Mahameed, Anil Shah, N. Joseph Deumite, Brent T. McLaurin, Ruth H. Strasser, Somnath Kumar, Genshan Ma, Aurel Cracan, Rajiv Mallik, Anthony Vlastaris, Francesco Perticone, Julio Alberto Aguilar Linares, Angel Moya, William Ashcraft, Steven Lupovitch, Renate Weinrich, Ralph F. Bosch, Gerald Ukrainski, Jon Arne Sparby, Norbert Schön, Pierre Jean Scala, Steven E. Hearne, Mark Roman, Ramin Farsad, Werner Rieker, Guillaume Cayla, Ramon Freixa, Hidemitsu Nakagawa, Kunihiro Nishida, Thomas J. Mulhearn, Tak W. Kwan, Jeffrey Shanes, Tiziana Tassinari, Ka Sing Lawrence Wong, Kneale Metcalf, Dominique Lejay, Daniel Savard, Pierre Chevallereau, Gilles O'Hara, Milan Mikus, Hiroshi Fukunaga, Olga Korennova, Xavier Ducrocq, Edvard Berngard, Mario Bo, Hoi Fan Chow, E. Ronner, Yuriy Grinshstein, Amparo Mena, Sidiqullah Rahimi, Axel Brandes, Shigenobu Bando, Freddy Del-Carpio Munoz, Jonathan L. Halperin, Ronald D. Jenkins, Carlos Rodríguez Pascual, Alain Lacroix, Sergio Agosti, Franklin Handel, Aylmer Tang, Nan Jiang, Diana A. Gorog, Dimitrios Stakos, Gerald Greer, Dudley Goulden, Martin Grond, Oran Corey, Stellan Bandh, Efrain Gonzalez, Alexander Klein, Jacques Scemama, Amelie Elsaesser, Nathan Foster, Francesco Fedele, Dinesh Mistry, Alberto Caccavo, Bjørn Bratland, Jean Marc Davy, D. J. Boswijk, Abdullah Al Ali, Muhammad Khalid, Terry McCormack, Clare Seamark, Enrico Passamonti, Zoran Olivari, Simon W Dubrey, Wlodzimierz Musial, Antonio Martín Santana, Jianqiu Liang, Manuel de Mora, Dmitry Dupljakov, Nicholas Jones, Mohamed Alshehri, Paul Charbel, John Bullinga, Petr Polasek, Hossein Almassi, Reza Mehzad, Gamal Hussein, Marcus Wiemer, Ali Sharareh, Alexandra Finsen, David Huckins, Denis Angoulvant, Matthias Leschke, Craig Vogel, Stefan Schuster, Juan E. Mesa, Yong Seog Oh, Axel De La Briolle, Jacek Kowalczyk, Louise Shaw, Eduardo de Teresa, Stefan Naydenov, Hubert Vial, Ian I Joffe, Christoph Kleinschnitz, Takeshi Yamashita, A. Salvioni, Aman M. Shah, Michael Renzi, Claude Brunschwig, Ioannis Styliadis, Ravi Bhagwat, Julian Coronel, Asok Venkataraman, Zayd Eldadah, Dinesh Singal, Byung Chun Jung, Michael Lillestol, Mirza S. Baig, Jose Polo, Ira Dauber, Olga Barbarash, Kristina Zint, Pavel Galin, P. J. A. M. Brouwers, Ki Byeong Nam, Andrey Ezhov, Kevin F. Browne, Iveta Sime, Tetsuo Sakai, Jean Louis Georges, Manish Jain, Alexey Nizov, Jean Dillinger, Arif Elvan, John Barton, Rainer Zimmermann, Junji Kanda, Clare Holmes, Werner Jung, Aurélien Miralles, Tatiana Novikova, Steven Georgeson, Yorihiko Higashino, Akira Yamada, David Sprigings, Haroon Rashid, J. W.M. Eck van, Bernard Erickson, Barry Seidman, Koji Kajiwara, Kannappan Krishnaswamy, Daniel Ferreira, Sébastien Armero, Brian Wong, Dong Gu Shin, Ludovic Chartier, Priit Kampus, Francisco Marín, Rickey Manning, Martin Köhrmann, Edward J. Kosinski, Bengt Johansson, Y. S. Tuininga, Simon Cattan, Sergio Dubner, Imran Dotani, Wenchi Kevin Tsai, Gregorio Sanchez, Edwin Blumberg, Charles Crump, Frank Jäger, Christoforos Olympios, Matthew Hoghton, Xinwen Zhao, Derek Muse, Alexandre Guignier, Toby Black, Yuichiro Takagi, Phil Keeling, Richard A. Bernstein, Omar Elhag, Jean Ernst Poulard, Fernando Gabriel Manzur Jattin, James Hampsey, Shahid Mahmood, Steffen Behrens, Tianlun Yang, Elena Dotcheva, Krishnan Challappa, Nam Ho Kim, Claudio Cavallini, Eric Espaliat, Martin James, June Soo Kim, Marc Roelke, Harold Thomas, Charles A. Shoultz, Rami El Mahmoud, José Francisco Kerr Saraiva, Jürgen vom Dahl, Xuebo Liu, Dong Ju Choi, Sergio Mondillo, Ian Parker, Kazuya Yamamoto, Rafael Martin Suarez, Karla M. Kurrelmeyer, Akber Mohammed, Nikitas Moschos, Benoit Coutu, Georgios Hananis, Hamed M. Zuhairy, Giovanni Baula, Suchdeep Bains, Menno V. Huisman, Heng Jiang, Jaroslaw Sek, Yoto Yotov, Malik Ali, Dalmo Antonio Ribeiro Moreira, Torben Larsen, Raed Osman, Marie Paule Houppe Nousse, Shulin Wu, Arturo Raisaro, Efrain Alonso Gomez Lopez, Violeta Cindea Nica, Eduardo Julián José Roberto Chuquiure Valenzuela, Wladmir Faustino Saporito, Changsheng Ma, Francesco Romeo, Jorge Martínez, M. Shakil Aslam, Kenneth J. Rothman, Kamal Al Ghalayini, Magdy Mikhail, Charles Augenbraun, Andreas Wilke, Peter Goethals, John D. McClure, Humberto Rodriguez Reyes, Peter Schoeniger, Nabil Jarmukli, Elizabeth S. Kaufman, Nathalie Duvilla, Jens Wicke, Kausik Chatterjee, Philippe Audouin, Dragan Kovacic, Xingwei Zhang, Brad Frandsen, Alberto Conti, Francisco Aguilar, Sasalu Deepak, Geir Heggelund, David S. Rosenbaum, Sergey P. Golitsyn, Alessandro Capucci, Rodolfo Sotolongo, Begoña Sevilla, François Poulain, Thomas Ronzière, Naseem Jaffrani, Dominik Michalski, Jose Lopez-Sendon, Silvia Di Legge, Bernard Jouve, Chang Sheng Ma, Robert Parris, Sumeet K. Mainigi, Jing Yao, Lars Udo Krause, Ulrich Tebbe, Quansan Zhang, Mathieu Amelot, Peter Crean, Benzy J. Padanilam, Nicolas Breton, Fernando Tomas Lanas Zanetti, Subhash Banerjee, Andrew I. Cohen, Michel Galinier, Jacek Miarka, Gerian Grönefeld, Vicente Bertomeu, Mariusz Gierba, Danny, Anna Ferrier, Luciano Marcelo Backes, Lianqun Cui, Eun-Seok Shin, Andreas Meinel, Jay Koons, Jen Yuan Kuo, Brett Graham, Antonio Garcia Quintana, Michael Hill, Sylvain Destrac, Janko Szavits-Nossan, Shanglang Cai, Joaquín Osca, Luis Aguinaga, Hemal M. Nayak, Chander Arora, Shinji Tayama, Diana Delić Brkljačić, Tiemin Jiang, Miguel Agustin Reyes Rocha, Ronan Collins, Davide Imberti, Kwang Soo Cha, Matthias Gabelmann, Alfredo Astesiano, Christian Weimar, William Eaves, Tatiana Ionova, Khalid Almuti, Thierry Schaupp, Bernhard Paul Lodde, Darlene Elias, Yuichiro Nakamura, Raed Al-Dallow, Eric Parrens, Weihua Li, Alan Bell, Noah Israel, Nadezda Rozkova, Nediljko Pivac, Nooshin Bazargani, Armando Pineda-Velez, Hyung Wook Park, Amin Karim, Clemens Steinwender, Davor Milicic, Gonzalo Barón, Robert Topkis, Mehrdad Ariani, Craig S. Barr, Paulo Bettencourt, Roberto Zanini, Andrew Moriarty, Pascal Goube, Fausto Rigo, Irene Madariaga, Atsushi Sueyoshi, Małgorzata Lelonek, Kevin R. Wheelan, Richard Huntley, Donald Brautigam, Jacek Gniot, Ido Lori, Dragos Vinereanu, Daniel Lee, Kouki Watanabe, Michael Vargas, Natalya Koziolova, James S. Zebrack, Basel Hanbali, Cesare Greco, José Luis Zamorano, Rajesh Patel, Fernando Carvalho Neuenschwander, Sergio Luiz Zimmermann, Shuiping Zhao, Pedro Adragão, Karl Heinz Schmitz, Abdelfatah Alasfar, Olga Ferreira de Souza, David N. Pham, Mark Dayer, Thomas Davee, Yoshiki Hata, Mika Skeppholm, Martin O'Donnell, David Molony, Joe Hargrove, Hani Sabbour, Pascal Defaye, Jochen Bott, Dora Ines Molina de Salazar, Anthony Clay, Giancarlo Landini, Michael McGuire, Dae Kyeong Kim, A. Shekhar Pandey, Bouziane Benhalima, Serge Cohen, Aamir Cheema, Matthias Claus, Marcus L. Williams, Qiangsun Zheng, Karim Bakhtiar, Hailong Lin, Sergio Berti, David Hartley, Libor Nechvatal, Rami Mihail Chreih, Domingo Pozzer, James Capo, John Floyd, Bhola Rama, Harald Darius, Ioannis Mantas, Pareed Aliyar, Carlos Barrera, Galina Ketova, Mark Chang, Alan J. Bank, José Ferreira Santos, Samir Turk, Lakshmanan Sekaran, Adam Ellery, Aurélie Buhl, Naomasa Miyamoto, Kuo Ho Yeh, Nicolas Mousallem, Hassan Soda, Dimitrios J. Richter, Zhaohui Wu, Tim Edwards, Kai Sukles, Koji Maeno, Huanyi Zhang, Paolo Verdecchia, Alexandros Gkotsis, Joe Pouzar, Philippe Berdagué, Edoardo Gronda, Olesya Rubanenko, Cristian Podoleanu, Mariano Ruiz Borret, Guillermo Llamas Esperon, Iveta Mintale, Hideki Shimomura, Dadong Zhang, Angelo Amato Vicenzo de Paola, Kenneth Butcher, Pascal Tessier, Minang Turakhia, Peter Svensson, Shabbir Reza, Herbert Pardell, Wilfried Lang, Holger Poppert, Alan Ackermann, Olivier Citerne, Emil Hayek, Yang Zheng, Jin bae Kim, Lorenzo Fácila, Tetsuo Hisadome, Li Sun, Panagiotis Vardas, Angel Grande, Piers Clifford, C. Zwaan van der, Nicki Law, Ilsbe Salecker, Steven Isserman, Shozo Tanaka, Dorothee B. Bartels, Yann Hemery, Susanna Cary, Mehiar El-Hamdani, Indira Natarajan, Miney Paquette, C. Wilson Sofley, Charles C. Gornick, Fu-Tien Chiang, Ellen Bøhmer, Hiroki Yamanoue, Toru Nakayama, Chakri Yarlagadda, Ciro Indolfi, Narendra Singh, Juan Carlos Nunez Fragoso, Eisho Kyo, Laurent Deluche, Andreas Götte, Stephen Phlaum, Jong Sung Park, Paresh Mehta, Terrence C. Hack, Fred Cucher, Olivier Dibon, Chia Theng Daniel Oh, Shannon Twiddy, Sean Connors, Edo Bottacchi, Beata Wożakowska-Kapłon, Ronald B. Goldberg, Jordi Bruguera, James J. Kmetzo, Jeanne Wei, John Kazmierski, Pilar Mazón, M Frais, Kazuya Kawai, Dimitrios Alexopoulos, Abayomi Osunkoya, Wanda Sudnik, Ramon Horacio Limon Rodriguez, William J. French, Ira Lieber, Rajesh Aggarwal, Stuart W. Zarich, John A. Puleo, David Cudmore, Jost Henner Wirtz, Ute Altmann, Kyung Tae Jung, Jennifer Litchfield, Jei Keon Chae, Rainer Dziewas, James Neiman, Karin Rybak, Galina Chumakova, Riccardo Pini, Richard Oliver, Benoit Lequeux, Athanasios J. Manolis, Luisa Fonseca, César A. Jardim, Katsuhiro Matsuda, Paul Hermany, Ming Luo, Ronnie Garcia, Oscar Pereira Dutra, John Culp, Amrit Pal Singh Takhar, Victor Howard, Oyidie Igbokidi, Kuo Yang Wang, Britta Goldmann, Thomas Walter, Mohamed K. Al-Obaidi, Antonio Pose, Christine Teutsch, Arthur J. Labovitz, Thomas Folk, Nell Wyatt, A. Huizenga, Benhur Henz, Konstantin Protasov, Petra Maskova, Ioannis Goudevenos, Kier Huehnergarth, Elena Kinova, Georgios Stergiou, Guohai Su, Hüseyin Ince, Chi Hung Huang, Winfried Haerer, Saad Al Ismail, Michael Gabris, Brian Carlson, Feng Liu, Yansheng Li, Luis Gustavo Gomes Ferreira, Radosław Lenarczyk, Ruben Omar Iza Villanueva, Nandkishore Ranadive, Yong Xu, Oscar Saenz Morales, Wayne Turner, Aleksey Khripun, Paul G. Grena, Yusuke Fujino, Abraham Salacata, Aleksandar Knezevic, Fouad Elghelbazouri, Hamid Bayeh, Mikhail Torosoff, Martin Cooper, Alenka Mavri, Marina Freydlin, Vassilios Vassilikos, Naresh Ranjith, Laurent Prunier, E. Hoffer, George Mitchell, Javier León Jiménez, S.S. Kabbani, Waldemar Krysiak, Emmanuel Nsah, John Ip, Charles B. Eaton, Jérome Thevenin, Dimitrios Chrysos, Asaad Bakbak, L. Steven Zukerman, Maria Grazia Bongiorni, Matthias von Mering, Lisa Alderson, Jean Joseph Muller, Yann Jamon, Roger Moore, Harinath Chandrashekar, Athanasios Pras, Venkatesh Nadar, B. J. Berg van den, Tomas Ripoll, Eric Van De Graaff, Patrick Dary, Peter L. Schwimmbeck, James Poock, Robert Schnitzler, Rohit Arora, Vuong DuThinh, Uwe Gremmler, Nuno Raposo, Chirag Sandesara, Ping Yen Bryan Yan, Junya Shite, Andrea Berz, Isabel Egocheaga, Karine Lavandier, Jose M. Teixeira, Ewart Jackson-Voyzey, Mayar Jundi, Ignacio Iglesias, Stephen Bloom, Hans Rickli, Rudolph Evonich, Giulio Molon, Vinay Shah, Salvador Bruno Valdovinos Chavez, Walter Ageno, Mauro Esteves Hernandes, Ali Ghanbasha, Stefan Regner, Luc De Wolf, Abdel El Hallak, Mohammad Shoukfeh, Francesco Musumeci, Pablo Andres Sepulveda Varela, Gershan Davis, Xianyan Jiang, Matthew Ebinger, Xiangdong Xu, Andreas Winkler, T. A. Simmers, Olivier Dascotte, Dominique Magnin, Karen Mahood, Carolina Guevara Caiedo, Zulu Wang, Hung-Fat Tse, John Camm, Didier Cadinot, Javier Aguila Marin, Juan Jose Olalla, Tamara Everington, Sherryn Roth, Feliz Alvaro Medina Palomino, Gregg Coodley, Wenhui Liu, G. Y. H. Lip, Ricky Ganim, Paul Ainsworth, Luiz Eduardo Fonteles Ritt, Yalin Liu, Sung Won Jang, Percy Berrospi, Dhananjai Menzies, Julien Pineau, Robert J. Jeanfreau, Hervé Buathier, John D. Osborne, Ted S. N. Lo, Li Fern Hsu, Xi Su, Beate Wild, Alvaro Rabelo Alves, Tomas Cieza-Lara, Neeraj Prasad, Yoshinori Seko, Jaydutt Patel, Malte Kuniss, Guy Chouinard, Jacek Morka, Frank Rubalcava, Fran Adams, Ignacio Rodriguez Briones, Vivek Sharma, Xinhua Wang, Amir Malik, Walid Amara, Adnan El Jabali, José Arturo Maldonado Villalon, Frederic Georger, Hong Ma, Steffen Schnupp, Nolan Mayer, Adam Sokal, Nasser Abdul, Gérald Phan Cao Phai, Jorge Hugo Blanco Ibaceta, Ramakrishnan Iyer, Yves Cottin, Barry Troyan, Achim Küppers, Anastas Stoikov, Jasjit Walia, Bruce Iteld, Abdul Alawwa, Christos Milonas, Frank Mibach, Mahfouz El Shahawy, H.William Stites, Neerav Shah, Clifford Ehrlich, Zia Ahmad, Furio Colivicchi, and Laszlo Karolyi

Subjects
medicine.medical_specialty, business.industry, Atrial fibrillation, 030204 cardiovascular system & hematology, medicine.disease, Dabigatran, 03 medical and health sciences, 0302 clinical medicine, Stroke prevention, Antithrombotic, Emergency medicine, medicine, In patient, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, Prospective cohort study, business, Stroke, Fibrinolytic agent, medicine.drug
Abstract

Background: GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic t...

Published
2017

6. Rationale and design of the First Brazilian Cardiovascular Registry of Atrial Fibrillation: The RECALL study

Author

Otavio Berwanger, Luiz Alberto Mattos, Fernanda Marciano Consolim-Colombo, Adalberto Lorga Filho, Sabrina Bernardez-Pereira, Angelo Amato Vicenzo de Paola, Jadelson Pinheiro de Andrade, Renato D. Lopes, and Márcio Jansen de Oliveira Figueiredo

Subjects
Adult, Male, Research design, Pediatrics, medicine.medical_specialty, Population, Electric Countershock, MEDLINE, Hemorrhage, 030204 cardiovascular system & hematology, Electrocardiography, 03 medical and health sciences, 0302 clinical medicine, Atrial Fibrillation, Humans, Medicine, International Normalized Ratio, Prospective Studies, Registries, 030212 general & internal medicine, Prospective cohort study, education, Stroke, education.field_of_study, business.industry, Warfarin, Anticoagulants, Atrial fibrillation, medicine.disease, Patient Care Management, Discontinuation, Research Design, Female, Cardiology and Cardiovascular Medicine, business, Anti-Arrhythmia Agents, Brazil, medicine.drug
Abstract

Background Atrial fibrillation (AF) is an important and growing public health problem worldwide, but data about its actual prevalence, therapeutic management, and clinical outcomes in middle- to low-income countries are scarce. Design The First Brazilian Cardiovascular Registry of Atrial Fibrillation (the RECALL study) will assess demographic characteristics and evidence-based practice of a representative sample of patients with AF in Brazil. The prospective, multicenter registry has a planned sample size of around 5,000 patients at approximately 80 sites. Eligibility criteria include age >18 years and permanent, paroxysmal, or persistent AF documented by electrocardiogram, 24-hour Holter monitoring, or device interrogation. Patients will be followed up through 1 year after enrollment. Information on laboratory tests, echocardiographic data, medication use, and clinical outcomes will be obtained. Various aspects of the population will be described, including demographic characteristics; antithrombotic therapies; antiarrhythmic agents; level of control of international normalized ratio (by average time within the therapeutic range) among patients using vitamin K antagonists; rates of warfarin discontinuation; outcomes such as death, stroke, systemic embolism, and major bleeding within 1 year after enrollment in the study; and rates of electrical cardioversion, percutaneous ablation of AF, ablation of the atrioventricular junction, and pacemaker/cardioverter-defibrillator implantation. Summary RECALL is the first prospective, multicenter registry of AF in Brazil. This study will provide important information about demographics, practice patterns, treatments, and associated outcomes in patients with AF. The results of this registry will also allow Brazilian data to be put in perspective with other AF registries across the world and provide opportunities to improve care of patients with AF in Brazil.

Published
2016

7. Relation between Age Group and Accessory Pathway Anatomical Location

Author

Fabiana Piech Nunes Ferro, Maria Alaíde Mendonça, Ivan Romero Rivera, Carlos Romério Costa Ferro, Angelo Amato Vicenzo de Paola, Agenor Barros, Claudio Cirenza, Pedro Henrique Albuquerque, Jadilma Mafra Barbosa, Marcio Robério Costa Ferro, and Francisco de Assis Costa

Subjects
Correlation, medicine.medical_specialty, Anatomical location, Age groups, business.industry, Refractory period, Internal medicine, Cardiology, Medicine, Accessory pathway, Presentation (obstetrics), business
Abstract

There are many factors that explain this relation between APs and age, and one possible mechanical explanation may be differences in electrophysiological properties, such as conduction speed and refractory period of APs and atrio- ventricular nodes. The objective of this study was to evaluate the correlation between age groups and gender, presentation pattern (manifest or concealed) and anatomical distribution of APs. Although APs have a genetically mediated transmission model, there is no uniformity in their presentation, and differences can be observed in their distribution depending on gender and onset age, in clinical and electrocardiographic manifestations.

Published
2018

8. A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial

Author

Dragos Vinereanu, Renato D Lopes, M Cecilia Bahit, Denis Xavier, Jie Jiang, Hussein R Al-Khalidi, Wensheng He, Ying Xian, Andrea O Ciobanu, Deepak Y Kamath, Kathleen A Fox, Meena P Rao, Sean D Pokorney, Otavio Berwanger, Carlos Tajer, Pedro G M de Barros e Silva, Mayme L Roettig, Yong Huo, Christopher B Granger, Justo Carbajales, Javier Neri Ceferino Gómez, Mario Bruno Principato, María Alejandra Von Wulffen, Jorge Galperín Rafael Salvador Acunzo, Ricardo Renato Bonato, Natalia Ciampi, Alberto Babil Marani, Cristian Gustavo Panigadi, Silvia Gabriela Pastura, Leonardo Martín Onetto, Cecilia Rafaela Moya, Nadia Budassi, Marisol Valle, Daniel Camerini, Enrique Monjes, Federico Zabala, Juan Pablo Ricart, Luis Medesani, Eduardo Noe Ortuño Campos, Fabián Ferroni, Mariana Foa Torres, Daniel Omar Fassi, Fernando Javier Díaz Bosio, Gabriel Edgardo Pérez Baztarrica, Teresa Zúñiga Infantas, Daniela Perlo, Celso Fernando García, Rubén García Durán, Luisina García Durán, Cecilia Alejandra Pettinari, Marisa Liliana Vico, Paulina Virginia Lanchiotti, Mariela Soledad Gómez, Carlos Alberto Poy, Franco Sebastián Grazziani, Marcela Julieta Laspina, María Laura Poy, María Cecilia Bahit, Marilia García, Renato D. Lopes, Pedro Gabriel Melo de Barros e Silva, Flávia Egydio, Elissa Restelli, Anelise Kawakami, Tamara Colaiácovo Soares, Mayara Vioto Valois, Tauane Bello Duarte, Lilian Mazza Barbosa, Angelo Amato Vicenzo de Paola, Thiago Librelon Pimenta, Gabriela Dal Moro Jeronimo, Bruna S. Fernandes da Costa, Enia Lucia Coutinho, Andressa Zulmira A. Guerrero, Lilia Nigro Maia, Marcelo Arruda Nakazone, Maria Angelica Teixeira Lemos, Osana Maria Coelho Costa, Ana Paula Demore, Roberta Parra Brito, Camila Dal Bon Melo, Nadielly Codonho Góes, Osvaldo Lorenço, Luiz Otavio Maia Gonçalves, Kátia Nishiama, Tiago Aparecido Maschio de Lima, Luciano Marcelo Backes, Keyla Liliana Alves de Lima Deucher, Milena Pozzatto Rodrigues, Dunnia Monisa Baldissera, José Basileu Caos Reolão, Tais Alves dos Santos, Fernanda Michel Birck Freisleben, Níncia Lucca da Silveira Kaross, Jéssika Tzervieczenski Montovani, Maiara Cantarelli, Aline Lucion, Luciano do Amarante, Priscila Foscarini, Claudia de Mello Perez, Fernanda Ribeiro França, Lisa Fialho, Helena Cramer Veiga Rey, Epotamenides Maria Good God, Estêvão Lanna Figueiredo, Gustavo Fonseca Werner, Jose Carlos de Faria Garcia, Bruna Azevedo, Luiz Carlos Vianna Barbosa, Ernaldo Pardi, Márcia Domingos Oliveira, Toshie Martinelli, Roseli Gomes Cavalini, Michele Santos Montoni de Moraes, Adalberto Menezes Lorga Filho, Eduardo Palmegiani, Thiago Baccilli Cury Megid, Clotildes S.P. Queirantes, Thamyres Santini Arroyo Cruz, Pengkang He, Xiaolan Zhou, Na Zhou, Mingzhong Zhao, Juan Yu, Yong Cheng, Lijun Wang, Lili Liu, Shuwang Liu, Lei Li, Aihua Li, Xiaochen Yuan, Guangwei Xia, Zhirong Wang, Chengzong Li, Wensu Chen, Qiang Tang, Qunzhong Tang, Weiting Xu, Xinyi Zhu, Bin Hou, Wenjian Ma, Chongquan Wang, Qiaoyun Jin, Jianan Wang, Xiaojie Xie, Johny Joseph, Deepak Davidson, Joby K. Thomas, Tony V. Kunjumon, Tibin Stephen, Kamlesh Fatania, Gaurav Rathi, Kinjal Garala, Dhruval Doshi, Kiron Varghese, Srilakshmi MA, Lumin Sheeba, Shantha Kumar, Malipeddi Bhaskara Rao, Kodem Damodara Rao, Anjan Kumar Vuriya, Mandula Padma Kumari, Bidita Khandelwal, Mona Dhakal, Nitin Srivastava, Dheeraj Khatri, Shova Moktan, Rajeev Gupta, Sanjeeb Roy, Kapil Kumawat, Mukesh Sharma, K.K. Sharma, Narendra Jathappa, B.H. Lokesh, Shilpa Kariyappa, A.C. Leela, K.C. Someshwara, Soaham Desai, Devangi Desai, Kunj Patel, Sujal Patel, Maulik Bhartiya, Bhupendra Narayan Mahanta, Dibya Jyoti Dutta, Ghanashyam Rajkonwer, Sandeep Kumar Gupta, Ashok Kumar Mishra, Akansha Singh, Naveen Kesarwani, Shivendra Kumar, Ovidiu Chioncel, Adriana Balan, Nicolae Carstea, Gabriel Tatu Chitoiu, Stelian Cornaciu, Mircea Cinteza, Roxana C. Rimbas, Doina Dimulescu, Luminita Ionescu, Ana Fruntelata, Nicoleta Dumitru, Dan Gaita, Roxana Pleava, Adriana Iliesiu, Gabriela Uscoiu, Daniel Lighezan, Roxana Buzas, Crina J. Sinescu, Ana-Maria Avram, Sorina Baldea, Ruxandra Dragoi Galrinho, Stefania L. Magda, and Lavinia Matei

Subjects
Male, medicine.medical_specialty, China, MEDLINE, Argentina, Administration, Oral, India, Hemorrhage, 030204 cardiovascular system & hematology, law.invention, Feedback, Medication Adherence, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Patient Education as Topic, law, Risk Factors, Internal medicine, Intervention (counseling), Atrial Fibrillation, medicine, Humans, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Stroke, Aged, business.industry, Romania, Anticoagulants, Atrial fibrillation, General Medicine, Odds ratio, Middle Aged, medicine.disease, Drug Utilization, Stroke prevention, Physical therapy, Education, Medical, Continuing, Female, business, Brazil
Abstract

Summary Background Oral anticoagulation is underused in patients with atrial fibrillation. We assessed the impact of a multifaceted educational intervention, versus usual care, on oral anticoagulant use in patients with atrial fibrillation. Methods This study was a two-arm, prospective, international, cluster-randomised, controlled trial. Patients were included who had atrial fibrillation and an indication for oral anticoagulation. Clusters were randomised (1:1) to receive a quality improvement educational intervention (intervention group) or usual care (control group). Randomisation was carried out centrally, using the eClinicalOS electronic data capture system. The intervention involved education of providers and patients, with regular monitoring and feedback. The primary outcome was the change in the proportion of patients treated with oral anticoagulants from baseline assessment to evaluation at 1 year. The trial is registered at ClinicalTrials.gov, number NCT02082548. Findings 2281 patients from five countries (Argentina, n=343; Brazil, n=360; China, n=586; India, n=493; and Romania, n=499) were enrolled from 48 clusters between June 11, 2014, and Nov 13, 2016. Follow-up was at a median of 12·0 months (IQR 11·8–12·2). Oral anticoagulant use increased in the intervention group from 68% (804 of 1184 patients) at baseline to 80% (943 of 1184 patients) at 1 year (difference 12%), whereas in the control group it increased from 64% (703 of 1092 patients) at baseline to 67% (732 of 1092 patients) at 1 year (difference 3%). Absolute difference in the change between groups was 9·1% (95% CI 3·8–14·4); odds ratio of change in the use of oral anticoagulation between groups was 3·28 (95% CI 1·67–6·44; adjusted p value=0·0002). Kaplan-Meier estimates showed a reduction in the secondary outcome of stroke in the intervention versus control groups (HR 0·48, 95% CI 0·23–0·99; log-rank p value=0·0434). Interpretation A multifaceted and multilevel educational intervention, aimed to improve use of oral anticoagulation in patients with atrial fibrillation and at risk for stroke, resulted in a significant increase in the proportion of patients treated with oral anticoagulants. Such an intervention has the potential to improve stroke prevention around the world for patients with atrial fibrillation. Funding Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Daiichi Sankyo, and Pfizer.

Published
2017

9. Correlation of accessory pathway location with gender and their manifest or concealed presentation

Author

Maria Alayde Mendonça, Carlos Romério Costa Ferro, Claudio Cirenza, Ivan Romero Rivera, Francisco A. Costa, Fabiana Piech Nunes Ferro, Angelo Amato Vicenzo de Paola, Jadilma Mafra Barbosa, Alfredo Dias de Oliveira Filho, and Rui Póvoa

Subjects
Adult, Male, medicine.medical_specialty, Bundle of His, Accessory pathway, 030204 cardiovascular system & hematology, Left posterior, Correlation, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Retrospective Studies, Sex Characteristics, business.industry, Significant difference, Mean age, Reentry, Middle Aged, Accessory Atrioventricular Bundle, Cardiology, Right posterior, Atrioventricular Node, Tachycardia, Ventricular, Female, Cardiology and Cardiovascular Medicine, business
Abstract

Background Atrioventricular reentrant tachycardias account for approximately one third of cases referred for electrophysiological study (EPS). The anatomical substrate responsible for the reentry is an accessory pathway (AP) able to conduct the electrical stimulus in an anterograde, retrograde or bidirectional manner. Objective To evaluate the correlation of AP location with the male and female genders and AP clinical presentation, whether manifest or concealed. Methods Retrospective observational study including 942 consecutive patients, all diagnosed with EPS-confirmed AP from January 1994 to December 2008. APs were classified into eight anatomical groups: left lateral (LL), left posterior (LP), left posteroseptal (LPS), right posteroseptal (RPS), right midseptal (RMS), right anteroseptal (RAS), right lateral (RL), and right posterior (RP). Results Of the 942 patients, 52.6% were males. The mean age was 31.2±13.8years. As regards gender, APs were more prevalent among men. However, a statistically significant difference was observed only in the LPS (p=0.029) and RL (p=0.003) regions. In relation to the form of presentation of AP, the manifest form was more frequent than the concealed form in six of the eight regions studied, except for the LL and LPS regions. Conclusion AP predominated in males and the manifest form was more frequent than the concealed form in most of the regions studied.

Published
2016

10. Naproxen as Prophylaxis against Atrial Fibrillation after Cardiac Surgery: The NAFARM Randomized Trial

Author

Claudio Cirenza, Felipe Martini, Adauto Castelo Filho, João Batista Petracco, João Carlos Vieira da Costa Guaragna, Luiz Carlos Bodanese, Angelo Amato Vicenzo de Paola, Stevie Jorge Horbach, Renato D. Lopes, Rajendra H. Mehta, Nafarm Investigators, Duke Univ, Universidade Federal de São Paulo (UNIFESP), Pontificia Univ Catolica Rio Grande do Sul, and Brazilian Clin Res Inst

Subjects
Male, medicine.medical_specialty, Naproxen, Coronary artery bypass graft surgery, Placebo, law.invention, Postoperative Complications, Double-Blind Method, Randomized controlled trial, law, Atrial Fibrillation, medicine, Humans, Data monitoring committee, Prospective Studies, Prospective cohort study, Aged, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Atrial fibrillation, General Medicine, Acute Kidney Injury, Length of Stay, Middle Aged, medicine.disease, Intensive care unit, Surgery, Cardiac surgery, Intensive Care Units, Anesthesia, Early Termination of Clinical Trials, Nonsteroidal anti-inflammatory, Female, business, Brazil, medicine.drug
Abstract

PURPOSE: We sought to assess the effect of naproxen versus placebo on prevention of atrial fibrillation after coronary artery bypass graft (CABG) surgery.METHODS: in this randomized, double-blind, placebo-controlled, single-center trial of 161 consecutive patients undergoing CABG surgery, patients received naproxen 275 mg every 12 hours or placebo at the same dosage and interval over 120 hours immediately after CABG surgery. the primary outcome was the occurrence of atrial fibrillation in the first 5 postoperative days.RESULTS: the incidence of postoperative atrial fibrillation was 15.2% (12/79) in the placebo versus 7.3% (6/82) in the naproxen group (P = .11). the duration of atrial fibrillation episodes was significantly lower in the naproxen (0.35 hours) versus placebo group (3.74 hours; P = .04). There was no difference in the overall days of hospitalization between placebo (17.23 +/- 7.39) and naproxen (18.33 +/- 9.59) groups (P = .44). Intensive care unit length of stay was 4.0 +/- 4.57 days in the placebo and 3.23 +/- 1.25 days in the naproxen group (P = .16). the trial was stopped by the data monitoring committee before reaching the initial target number of 200 patients because of an increase in renal failure in the naproxen group (7.3% vs 1.3%; P = .06).CONCLUSIONS: Postoperative use of naproxen did not reduce the incidence of atrial fibrillation but decreased its duration, in a limited sample of patients after CABG surgery. There was a significant increase in acute renal failure in patients receiving naproxen 275 mg twice daily. Our study does not support the routine use of naproxen after CABG surgery for the prevention of atrial fibrillation. (C) 2011 Elsevier Inc. All rights reserved. . the American Journal of Medicine (2011) 124, 1036-1042 Duke Univ, Duke Clin Res Inst, Med Ctr, Durham, NC 27705 USA Universidade Federal de São Paulo, Div Invas Clin Electrophysiol, Dept Cardiol, São Paulo, Brazil Pontificia Univ Catolica Rio Grande do Sul, Div Cardiol, Porto Alegre, RS, Brazil Brazilian Clin Res Inst, São Paulo, Brazil Universidade Federal de São Paulo, Div Invas Clin Electrophysiol, Dept Cardiol, São Paulo, Brazil Web of Science

Published
2011

11. Doppler echocardiographic predictors of mortality in female rats after myocardial infarction

Author

Ednei Luiz Antonio, Izzo Helber, Antonio Carlos Carvalho, Valdir Ambrósio Moisés, Alexandra Alberta dos Santos, Angelo Amato Vicenzo de Paola, Paulo José Ferreira Tucci, and Ronald Luiz Gomes Flumignan

Subjects
Risk, medicine.medical_specialty, Hypertension, Pulmonary, Diastole, Myocardial Infarction, Infarction, symbols.namesake, Internal medicine, medicine, Confidence Intervals, Animals, Myocardial infarction, Rats, Wistar, Proportional Hazards Models, business.industry, Mortality rate, medicine.disease, Prognosis, Pulmonary hypertension, Echocardiography, Doppler, Rats, medicine.anatomical_structure, Ventricle, Heart failure, Multivariate Analysis, cardiovascular system, symbols, Cardiology, Regression Analysis, Female, Cardiology and Cardiovascular Medicine, business, Doppler effect
Abstract

Doppler echocardiogram is useful for the evaluation of anatomical and functional changes in late myocardial infarction (MI) in rats. However, no studies have evaluated the prognostic value of echocardiographic parameters 1 week after MI.Doppler echocardiogram was performed in 84 female Wistar rats 1 week after MI to determine infarction size, left chambers dimensions, fractional area change (FAC) of the left ventricle (LV), mitral inflow and tissue Doppler, myocardial performance index (MPI), and signs of pulmonary hypertension. The 365-day follow-up showed 53.6% mortality rate. Nonsurvivors showed larger (P.05) MI size and cavity dimensions, poorer diastolic and systolic function, and higher frequency of pulmonary hypertension. Parameters at early stage of MI associated with higher mortality risk by Cox multivariate regression model were FACor=37% (relative risk [RR] 3.78, 95% CI, 1.50-9.53), MPIor=0.60 (RR 3.49, 95% CI, 1.80-6.76), LV systolic areaor=0.26 cm(2) (RR 4.38, 95% CI, 1.88-10.21), E/E' ratioor=20.3 (RR 2.12, 95% CI, 1.15-4.34), and E/A ratio associated with FAC (RR 2.99, 95% CI, 1.44-6.18).Some diastolic and systolic Doppler echocardiographic parameters in rats may be able to predict late mortality risk after MI.

Published
2008

12. Lipid profile and cardiovascular risk in two Amazonian populations

Author

Francisco Antonio Helfenstein Fonseca, Claudine Maria Alves Feio, Costa Ea, Simone S Rego, Max N.B Feio, Maria Carolina Elias, Angelo Amato Vicenzo de Paola, Maria Cristina de Oliveira Izar, and Antonio Carlos Carvalho

Subjects
Adult, Male, Rural Population, lcsh:Diseases of the circulatory (Cardiovascular) system, Urban Population, Saturated fat, Population, fatores de risco, nutrição, lipids, Polyunsaturated fat, Animal science, Skin fold, lípides, Risk Factors, risk factors, Medicine, Diseases of the circulatory (Cardiovascular) system, Humans, education, National Cholesterol Education Program, Aged, education.field_of_study, Framingham Risk Score, Chi-Square Distribution, medicine.diagnostic_test, business.industry, Middle Aged, Dietary Fats, Lipids, nutrition, lcsh:RC666-701, Cardiovascular Diseases, RC666-701, Female, Cardiology and Cardiovascular Medicine, business, Lipid profile, Body mass index, Brazil
Abstract

OBJECTIVE: To compare the lipid profiles and coronary heart disease risks of 2 Brazilian Amazonian populations as follows: a riverside population (village of Vigia) and an urban population (city of Belém in the state of Pará). METHODS: Fifty individuals controlled for age and sex were assessed in each region, and the major risk factors for coronary heart disease were analyzed. RESULTS: According to the National Cholesterol Education Program (NCEP III) and using the Framingham score, both populations had the same absolute risk of events (Vigia = 5.4 ± 1 vs Belém = 5.7 ± 1), although the population of Vigia had a lower consumption of saturated fat (P

Published
2004

13. Mapping and ablation of idiopathic ventricular fibrillation

Author

Rukshen Weerasooriya, Mélèze Hocini, Jacques Clémenty, Josef Kautzner, Angelo Amato Vicenzo de Paola, Pierre Jaïs, Stéphane Garrigue, Dominique Lamaison, Dietrich Kalushe, Fernando Cruz, Michael Griffith, Michel Haïssaguerre, Fiorenzo Gaita, Thomas Arentz, Akihiko Nogami, D. C. Shah, Morio Shoda, and Laurent Macle

Subjects
Adult, Male, medicine.medical_specialty, Heart disease, Purkinje fibers, medicine.medical_treatment, Catheter ablation, Coronary Angiography, Sudden cardiac death, Purkinje Fibers, Physiology (medical), Internal medicine, medicine, Humans, Fibrillation, business.industry, Body Surface Potential Mapping, medicine.disease, medicine.anatomical_structure, Death, Sudden, Cardiac, Bigeminy, Ventricle, Anesthesia, Ventricular fibrillation, Ventricular Fibrillation, cardiovascular system, Cardiology, Catheter Ablation, Feasibility Studies, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Endocardium, Follow-Up Studies
Abstract

Background— Ventricular fibrillation is the main mechanism of sudden cardiac death. The feasibility of eliminating recurrent episodes by catheter ablation has not been reported. Methods and Results— Twenty-seven patients without known heart disease (13 men, 14 women, 41±14 years of age) were studied after being resuscitated from recurrent (10±12) episodes of primary idiopathic ventricular fibrillation; 23 had received a defibrillator. The first initiating beat of ventricular fibrillation had an identical electrocardiographic morphology and coupling interval (297±41 ms) to preceding isolated premature beats typically noted in the aftermath of resuscitation. These triggers were localized by mapping the earliest electrical activity and ablated by local radiofrequency delivery. Outcome was assessed by Holter and defibrillator memory interrogation. Premature beats were elicited from the Purkinje conducting system in 23 patients: from the left ventricular septum in 10, from the anterior right ventricle in 9, and from both in 4. The interval from the Purkinje potential to the following myocardial activation varied from 10 to 150 ms during premature beat but was 11±5 ms during sinus rhythm, indicating location at peripheral Purkinje arborization. The premature beats originated from the right ventricular outflow tract muscle in 4 patients. The accuracy of mapping was confirmed by acute elimination of premature beats during local radiofrequency delivery. During a follow-up of 24±28 months, 24 patients (89%) had no recurrence of ventricular fibrillation without drug. Conclusions— Primary idiopathic ventricular fibrillation is a syndrome characterized by dominant triggers from the distal Purkinje system. These sources can be eliminated by focal energy delivery.

Published
2002

14. Purkinje network is the origin of the beats in Catecholaminergic Bidirectional Ventricular Tachycardia and in the initiating beat of Short Coupling Variant of Torsade de Pointes

Author

Carlo Napolitano, Luis R. Leite, Marcio Fagundes, Fernando E.S. Cruz, Maia Ig, Lulgarde M. Vanheusden, Sá R, Silvia G. Priori, and Angelo Amato Vicenzo de Paola

Subjects
Catecholaminergic, medicine.medical_specialty, Bidirectional ventricular tachycardia, business.industry, Internal medicine, medicine, Cardiology, Beat (acoustics), business, Cardiology and Cardiovascular Medicine
Published
2002
Full Text
View/download PDF

15. Quinidine plus verapamil vs. quinidine alone to prevent recurrences of atrial fibrillation

Author

Angelo Amato Vicenzo de Paola and Henrique H. Veloso

Subjects
Quinidine, medicine.medical_specialty, business.industry, Sotalol, Atrial fibrillation, Torsades de pointes, medicine.disease, Anesthesia, Internal medicine, cardiovascular system, Cardiology, Medicine, Verapamil, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

The excellent PAFAC1 and SOPAT2 trials demonstrated that quinidine, in combination with verapamil, is at least equivalent to sotalol in the prevention of recurrences of atrial fibrillation (AF). The combination of verapamil with quinidine in this setting may be beneficial for several reasons. First, verapamil has the ability of suppressing after depolarizations underlying the onset of torsades de pointes, which justifies the low rate of pro-arrhythmic events observed with quinidine during the follow-up period of these trials.1–3 Secondly, it has been already demonstrated that …

Published
2005

16. Predictors of premature coronary artery disease

Author

Angelo Amato Vicenzo de Paola, S.S.M. Ihara, Mco Izar, Ieda Edite Lanzarini Lopes, Fah Fonseca, Simone C. Matheus, Gislaine A. Mendes, Acc Carvalho, Kasinski N, and L. Pinto

Subjects
medicine.medical_specialty, Framingham Risk Score, business.industry, Internal medicine, medicine, Cardiology, Premature coronary artery disease, Myocardial infarction, Cardiology and Cardiovascular Medicine, business, medicine.disease
Published
2000

18. Use of transesophageal echocardiography during implantation of aortic endoprosthesis (stent). Initial experience

Author

Cláudio Henrique Fischer, Orlando Campos Fº, José Honório de Almeida Palma da Fonseca, Cláudia Maria Rodrigues Alves, José Augusto Marcondes Sousa, Edgar Bezerra de Lira Fº, Antonio Carlos de Camargo Carvalho, Ângelo Amato Vicenzo de Paola, and Ênio Buffolo

Subjects
transesophageal echocardiography, stents, aortopathies, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

OBJECTIVE: To report the role played by transesophageal echocardiography during implantation of self-expanding aortic endoprostheses (stent) at a hemodynamics laboratory. METHODS: Thirteen patients underwent stent implantation in the descending thoracic aorta with the aid of transesophageal echocardiography during the entire procedure. Indications for stenting were as follows: 8 aortic dissections, 2 true aneurysms, 2 penetrating atherosclerotic ulcers, and 1 traumatic pseudoaneurysm. RESULTS: No complications resulting from the use of transesophageal echocardiography were observed. In 12 patients, the initial result was considered appropriate, with total or partial resolution of the major lesion confirmed by a posterior examination. In 1 patient, the procedure was suspended after transesophageal echocardiography and angiography showed that the proximal aortic diameter was inappropriate. Transesophageal echocardiography contributed to clarifying relevant points, such as aortic diameter, anatomic detail of the intimal lesion, and location and size of the communicating orifice. In addition, it facilitated placing the stent in the target lesion, reduced the time of exposure to radiation and the use of contrast medium, and provided rapid identification of intercurrent events, possibly reducing the total duration of the procedure. CONCLUSION: The use of transesophageal echocardiography during placement of aortic stents seems appropriate. The actual advantages of the procedure will be defined in a comparative prospective study.

Published
2001
Full Text
View/download PDF

19. Association between job related stress and cardiovascular health score in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Author

Priscila Teresa Peranovich Rocco, Itamar de Souza Santos, Isabela Judith Martins Benseñor, Frederico Navas Demetrio, and Angelo Amato Vicenzo de Paola

Subjects
business.industry, Medicine, business
Abstract

INTRODUÇÃO: Há evidências ligando o estresse psicossocial à saúde cardiovascular. Em importante parcela da população adulta, o trabalho é uma fonte de estresse. Este estudo objetiva analisar as associações entre o estresse relacionado ao trabalho e o escore de saúde cardiovascular ideal sugerido pela Associação Americana de Cardiologia (AHA - American Heart Association) nos participantes do Estudo Longitudinal da Saúde do Adulto (ELSA-Brasil) na linha de base. MÉTODOS: Foram analisados dados de 11 346 trabalhadores ativos com idade entre 35 e 74 anos (52,7% mulheres, média de idade 49,1 ± 7,2 anos), oriundos de seis centros de pesquisa em seis cidades brasileiras (São Paulo, Belo Horizonte, Porto Alegre, Salvador, Rio de Janeiro e Vitória), sem antecedentes de doença cardiovascular. O estresse relacionado ao trabalho foi avaliado utilizando a versão brasileira do Questionário Sueco de Demanda-Controle- Suporte (Swedish Demand-Control-Support Questionnaire), analisando demanda, uso de habilidades, autoridade decisória e suporte social. Para avaliar o conflito trabalho-família foi utilizado um questionário validado derivado do modelo de Frone com 4 questões avaliando os domínios: interferência do trabalho na família em termos de tempo, interferência do trabalho na família em termos de intensidade, interferência da família no trabalho e falta de tempo para lazer e auto-cuidado. O escore de saúde cardiovascular ideal (ESCI) foi calculado considerando-se os mesmos parâmetros estabelecidos pela AHA e que consistem de 4 fatores comportamentais (dieta, atividade física, índice de massa corpórea e tabagismo) e 3 biológicos (pressão arterial, glicemia de jejum e colesterol total) com valores de 0 (pior escore) a 7 (escore máximo ideal). O ESCI global foi subdividido em comportamental (0 a 4) e biológico (0 a 3). Foram construídos modelos de quasi-Poisson, brutos e ajustados, para analisar as associações entre o estresse relacionado ao trabalho e o ESCI (global, comportamental e biológico). Para a análise da associação entre a presença de estresse relacionado ao trabalho e a frequência do perfil ideal de cada métrica componente do ESCI, foram construídos modelos de regressão de Poisson com variância robusta. RESULTADOS: Nos modelos principais, encontramos que o ESCI global predito foi menor na presença de frequente falta de tempo para lazer e auto-cuidado nas mulheres (diferença relativa no escore predito [DREP]: -4,68%; intervalo de confiança de 95% [IC95%]: -7,43% a -1,86%). O ESCI comportamental foi o mais claramente associado ao estresse relacionado ao trabalho, tanto na amostra total quanto após estratificação por sexo. Nos homens, observamos associações negativas mais proeminentes com os domínios de estresse no trabalho (alta demanda [DREP: -3,85%; IC95%: -7,41% a -0,15%], baixa autoridade decisória [DREP: -4,19%; IC95%: -8,10% a -0,12%] e baixo suporte social [DREP: -4,33%; IC95%: -7,78% a -0,76%]). Nas mulheres, tanto domínios específicos de estresse no trabalho (baixo uso de habilidades [DREP: -4,40%; IC95%: -7,95% a -0,70%] e baixo suporte social [DREP: -4,13%; IC95%: -7,46% a -0,68%]) quanto de conflito trabalho-família (frequente interferência do trabalho na família em termos de intensidade [DREP: -5,00%; IC95%: -8,05% a -1,84%] e interferência da família no trabalho [DREP: -8,60%; IC95%: -13,46% a -3,47%]) mostraram associação negativa com o ESCI comportamental. A frequente falta de tempo para lazer e auto-cuidado mostrou associação negativa com o ESCI comportamental em ambos sexos (DREP: -6,12%; IC95%: -9,52% a -2,58% nos homens e DREP: -10,20%; IC95% -13,08% a -7,22% nas mulheres. O ESCI biológico mostrou associação positiva com o estresse relacionado ao trabalho em homens, o que pode ser explicado, ao menos parcialmente, por causalidade reversa. A atividade física foi a métrica mais associada ao estresse relacionado ao trabalho. CONCLUSÃO: Nesse estudo foram encontradas associações significativas entre o estresse relacionado ao trabalho e a saúde cardiovascular mensurada de acordo com o ESCI proposto pela AHA INTRODUCTION: Considerable data point to the influence of stress over cardiovascular health and work is a source of stress for many subjects. This study aims to analyse the association between job related stress and the Ideal Cardiovascular Health (ICH) score suggested by American Heart Association (AHA), in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) participants at baseline. METHODS: We analyzed data from 11,346 active workers aged 35 to 74 years (52.7% women, mean age 49.1 ± 7.2 years-old) from six centers in six Brazilian cities (Belo Horizonte, Porto Alegre, Sao Paulo, Salvador, Rio de Janeiro, and Vitoria), without overt cardiovascular disease. Job strain was assessed using the Brazilian version of the Swedish Job Demand-Control-Support Questionnaire, which was divided in job psychological demands, skill discretion, decision authority and social support. Workfamily conflict was assessed using a questionnaire based on the Frone model and validated for Brazilian Portuguese, which comprises four questions evaluating each of those domains: time and strain-based work interference with family, family interference with work and lack of time for personal care and leisure. The ICH score was calculated according to AHA criteria considering lifestyle (diet, physical activity, body mass index and smoking) and clinical (blood pressure, fasting plasma glucose and total cholesterol) metrics and scored in a 0 (worst) to 7 (best) range. We subdivided the ICH score in lifestyle (0 to 4) and clinical (0 to 3) ones and built crude and adjusted quasi-Poisson regression models to analyze the associations between job related stress and ICH scores (global, lifestyle and clinical). To analyze the association between job related stress and the frequency of each ICH score metric we built Poisson regression models with robust variance estimator. RESULTS: In main models, we found that the predicted global ICH score was lower in the presence of frequent lack of time for leisure and self-care in women (relative predicted score difference [rPSD]: -4.68%; 95% confidence interval [95%CI]: -7.43% to -1.86%). Lifestyle ICH scores were most clearly associated with work-related stress, both in the total sample and after stratification by sex. In men, we observed more prominent negative associations with the domains of job strain (high demand [rPSD: -3.85%; 95%CI: -7.41% to -0.15%], low decision authority [rPSD: -4.19%; 95%CI: -8.10% to -0.12%] and low social support [rPSD: -4.33%; 95%CI: -7.78% to -0.76%]). In women, both job strain (low skill discretion [rPSD: -4.40%; 95%CI: -7.95% to -0.70%] and low social support [rPSD: -4.13 %; 95%CI: -7.46% to -0.68%]), and work-family conflict domains (frequent strain-based work interference in the family [rPSD: -5.00%; 95%CI: -8, 05% to -1.84%] and family interference in work [rPSD: -8.60%; 95%CI: -13.46% to -3.47%]) showed a negative association with lifestyle ICH scores. Frequent lack of time for leisure and self-care was negatively associated with lifestyle ICH scores in both sexes (rPSD: -6.12%; 95%CI: -9.52% to -2.58% in men and rPSD: -10.20; 95%CI -13.08% to -7.22% in women). Clinical ICH scores showed a positive association with work-related stress in men, which can be explained, at least partially, by reverse causality. Physical activity was the ICH metric most associated with work-related stress. CONCLUSION: We found significant associations between work-related stress and cardiovascular health, according to the ICH score proposed by the AHA

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results