835 results on '"Alami, Mouad"'
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2. Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cells
3. Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors
4. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1
5. Overcoming Solubility Challenges: Liposomal isoCoQ‐Carbazole as a Promising Anti‐Tumor Agent for Inoperable and Radiation‐Insensitive cancers
6. Synthesis of Oxazino[4,3-a]indoles and biological applications
7. Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues
8. Recent advances in the synthesis of dibenzofurans
9. Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation
10. Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency
11. Developments of isoCombretastatin A-4 derivatives as highly cytotoxic agents
12. Isoginkgetin derivative IP2 enhances the adaptive immune response against tumor antigens
13. N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents
14. Chapitre 14 : De nouvelles perspectives en thérapie antivasculaire : pourquoi faire compliqué quand on peut faire simple ?
15. Overcoming Solubility Challenges: Liposomal isoCoQ-Carbazole as a Promising Anti-Tumor Agent for Inoperable and Radiation-Insensitive Cancers
16. Synthesis of Aza‐Heterocyclic Compounds with N‐Tosylhydrazones: Formation of Bi‐Indoles via Reductive Molybdenum Catalysis
17. Hydration of Unsymmetrical Internal Alkynes: Factors Governing the Regioselectivity
18. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation
19. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors
20. Synthesis, biological evaluation and molecular modeling studies of imidazo[1,2-a]pyridines derivatives as protein kinase inhibitors
21. Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells
22. Catalyst-Free Synthesis of Functionalized 4‑Substituted‑4H‑Benzo[d][1,3]oxazines via Intramolecular Cyclization of ortho-Amide‑N‑tosylhydrazones.
23. Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents
24. Site-Selective Palladium(II)-Catalyzed Methylene C(sp3)–H Diarylation of a Tropane Scaffold
25. GluN2C selective inhibition is a target to develop new antiepileptic compounds
26. Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors
27. Discovery of azaisoerianin derivatives as potential antitumors agents
28. Anti-Tumoral Effects of Anti-Progestins in a Patient-Derived Breast Cancer Xenograft Model
29. Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs
30. Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives
31. Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity
32. Biological Investigation of a Water-Soluble Isoginkgetin-Phosphate Analogue, Targeting the Spliceosome with In Vivo Antitumor Activity
33. Front Cover: Azoliums and Ag(I)‐N‐Heterocyclic Carbene Thioglycosides: Synthesis, Reactivity and Bioactivity (Eur. J. Org. Chem. 9/2022)
34. Azoliums and Ag(I)‐N‐Heterocyclic Carbene Thioglycosides: Synthesis, Reactivity and Bioactivity
35. Pd-Catalyzed Coupling of N-Tosylhydrazones with Benzylic Phosphates: Toward the Synthesis of Di- or Tri-Substituted Alkenes
36. Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90
37. Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1
38. Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4
39. Assessing the chemical diversity of an hsp90 database
40. Synthesis and Biological Activities of Pyrazino[1,2-a]indole and Pyrazino[1,2-a]indol-1-one Derivatives
41. Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells
42. Crystal structure of 3-[(2,2-dimethylchroman-6-yl)carbonylamino]-7-hydroxy- 8-methyl-2-oxo-2H-chromen-4-yl toluene-4-sulfonate, C29H27NO8S
43. Xphos ligand and platinum catalysts: A versatile catalyst for the synthesis of functionalized β-( E)-vinylsilanes from terminal alkynes
44. DMSO–PdI 2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles
45. De nouvelles perspectives en thérapie antivasculaire Pourquoi faire compliquer quand on peut faire simple ?
46. Diastereoselective Pd-Catalyzed Anomeric C(sp3)–H Activation: Synthesis of α-(Hetero)aryl C-Glycosides
47. Copper-catalyzed sulfonylation of N-tosylhydrazones followed by a one-pot C–N bond formation
48. Synthesis of axially chiral biaryl thioglycosides through thiosugar-directed Pd-catalyzed asymmetric C–H activation
49. Recent advances in the synthesis of pyrido[1,2-a]indoles
50. Synthesis of S-Trifluoromethyl S-Arylsulfoximine Thioglycosides through Pd-Catalyzed Migita Cross-Coupling
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