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Resumen Introduccion Estudios recientes en Europa y Estados Unidos muestran un posible aumento de la incidencia y la hospitalizacion por ictus isquemico en adultos jovenes, sin embargo, en Espana la informacion disponible de la tendencia es escasa. Por ello planteamos analizar la tendencia de hospitalizacion por ictus isquemico en adultos menores de 50 anos en la Region de Murcia entre 2006 y 2014. Metodo Se realizo un estudio retrospectivo de las altas de hospitalizacion por enfermedad cerebrovascular (ECV) extraidas del Registro del conjunto minimo de datos al alta hospitalaria. Se obtuvieron las tasas estandarizadas, desagregadas segun edad y subtipo de ECV. La tendencia de los episodios fue analizada mediante regresion de joinpoint, obteniendo la tasa estandarizada anual calculada y el porcentaje de cambio anual (PCA). Resultados Se identificaron un total de 27.064 altas por ECV en los 9 anos del estudio. Los episodios generados por ictus isquemico fueron los mas numerosos (61,0%), en pacientes entre 18 y 49 anos; entre los anos extremos, se registro un aumento del 26% de los episodios por ictus isquemico y del 29,2% de las tasas, mientras que en la regresion de joinpoint no se observo tendencia (PCA = 2,74%, p ≥ 0,05). Por el contrario, en mayores de 49 anos esta tendencia fue descendente (PCA = –1,24%, p Conclusiones No se ha identificado una tendencia en la hospitalizacion por ictus isquemico en adultos jovenes a pesar del descenso en adultos de mayor edad. Seria importante identificar las causas de este comportamiento desigual para desarrollar medidas especificas dirigidas al grupo de menor edad.

Introduction Recent studies conducted in Europe and the United States suggest upward trends in both incidence and hospitalisation rates for ischaemic stroke in young adults; however, data for Spain are scarce. This study analyses the trend in hospitalisation due to ischaemic stroke in adults aged under 50 years in the region of Murcia between 2006 and 2014. Method We performed a retrospective study of patients discharged after hospitalisation due to cerebrovascular disease (CVD); data were obtained from the regional registry of the Minimum Basic Data Set. Standardised rates were calculated, disaggregated by age and CVD subtype. Time trends were analysed using joinpoint regression to obtain the annual calculated standardised rate and the annual percentage of change (APC). Results A total of 27 064 patients with CVD were discharged during the 9-year study period. Ischaemic stroke was the most frequent subtype (61.0%). In patients aged 18 to 49 years, the annual number of admissions due to ischaemic stroke increased by 26%, and rates by 29.2%; however, the joinpoint regression analysis showed no significant changes in the trend (APC = 2.74%, P ≥ .05). By contrast, a downward trend was identified in individuals older than 49 (APC = –1.24%, P Conclusions No significant changes were observed in the rate of hospitalisation due to ischaemic stroke among young adults, despite the decline observed in older adults. Identifying the causes of these disparate trends may be beneficial to the development of specific measures targeting younger adults.