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Copyright of Chinese Journal of Applied Chemistry is the property of Chinese Journal of Applied Chemistry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the serum levels of low density lipoprotein receptor (LDLR) and dynamin 2 (DNM2) in elderly patients with chronic heart failure (CHF) and their clinical significance. Methods A total of 123 CHF patients (the CHF group) and 120 healthy people (the control group) were selected. According to New York Heart Association (NYHA) classification, there were 42 cases of grade Ⅱ, 61 cases of grade Ⅲ and 20 cases of grade Ⅳ in the CHF group. The serum levels of LDLR, DNM2 and cardiac function indexes were compared between the CHF group and the control group. Pearson correlation analysis was performed to analyze the correlation between LDLR, DNM2, left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) and N-terminal B-type brain natriuretic peptide precursor (NTprobNP). After six months of follow-up, CHF patients were divided into the good prognosis group (98 cases) and the poor prognosis group (25 cases). The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of LDLR and DNM2 for CHF with poor prognosis. Results Compared with the control group, the serum levels of LDLR, DNM2 and LVEF decreased in patients with different NYHA grades than those of the control group, while the levels of LVEDD and NT-proBNP were higher than those of the control group (P＜0.05). With the increase of NYHA classification, serum levels of LDLR, DNM2 and LVEF gradually decreased in CHF patients, while LVEDD and NT-proBNP levels gradually increased (P＜0.05). Serum levels of LDLR and DNM2 were positively correlated with LVEF in CHF patients, but negatively correlated with LVEDD and NT-proBNP (P＜0.01). The serum levels of LDLR and DNM2 were lower in the poor prognosis group than those in the good prognosis group (P＜0.05). The ROC curve showed that the area under the curve of LDLR combined with DNM2 in the diagnosis of poor prognosis in CHF patients was significantly higher [0.858 (95%CI: 0.751-0.965)] than that of LDLR [0.793 (95%CI: 0.668-0.919)] and DNM2 [0.777 (95%CI: 0.669-0.884)], the sensitivity and specificity were improved. Conclusion Serum levels of LDLR and DNM2 are decreased with the the increase of NYHA classification in CHF patients, which can reflect cardiac function. The combination of the two indicators is helpful to evaluate the prognosis of patients with CHF. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Natural Gas Industry is the property of Natural Gas Industry Journal Agency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the noninvasive indicators of indications for antiviral therapy in HBeAg - negative chronic hepatitis B virus (HBV) infection patients with alanine aminotransferase (ALT)=40 U/ L under the guidance of liver pathology. Methods A retrospective analysis was performed for the clinical data of 377 HBeAg - negative chronic HBV infection patients with ALT =40 U/ L who were hospitalized in Affiliated Hospital of Yan’an University, from October 2013 to August 2018 and underwent liver biopsy, among whom the patients with inflammatory activity < A2 and fibrosis stage < F2 were enrolled as non - antiviral therapy group(n =266), and the patients with inflammatory activity =A2 or fibrosis stage =F2 were enrolled as antiviral therapy group(n =111). The chi - square test was used for comparison of categorical data between two groups;the t - test was used for comparison of normally distributed continuous data between two groups, and the Mann - Whitney U test was used for comparison of non - normally distributed continuous data between two groups;univariate and multivariate binary logistic regression analyses were used to screen out the influencing factors for the initiation of antiviral therapy;the receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic efficiency of each indicator in determining the need for antiviral therapy in HBeAg - negative chronic HBV infection patients with ALT =40 U/ L. Results Of all 377 patients, 266 (70. 6% )did not need antiviral therapy for the time being, and 111 (29. 4% )had marked liver damage and thus needed active antiviral therapy. The multivariate analysis showed that liver stiffness measurement (LSM) (odds ratio [HR]=2. 003, 95% confidence interval [CI]:1. 647 - 2. 437, P <0.05), HBsAg (HR =1. 563, 95% CI:1. 110 -2. 200, P <0. 05), HBV DNA (HR =1. 519, 95% CI:1.173 -1. 966, P < 0. 05), and albumin (HR =0. 939, 95% CI:0. 884 -0. 998, P <0. 05)were independent influencing factors for the initiation of antiviral therapy. The ROC curve analysis showed that the area under the ROC curve (AUC)was 0. 749 (95% CI:0. 699 -0.799)for LSM, 0.642 (95% CI:0. 586 -0. 699) for HBV DNA, and 0. 565 (95% CI:0. 507 -0. 623) for HBsAg, and the combination of LSM, HBV DNA, and HBsAg had a larger AUC of 0. 779 (95% CI:0. 732 -0. 827). Conclusion The levels of LSM, HBV DNA, and HBsAg have a reference value in determining the initiation of antiviral therapy in HBeAg - negative chronic HBV infection patients with ALT=40 U/ L. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Tropical Medicine is the property of China Tropical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Southern Agriculture is the property of Journal of Southern Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Tropical Medicine is the property of China Tropical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To investigate the value of liver stiffness measurement (LSM) in the diagnosis of liver fibrosis degree in HBeAg-positive patients with chronic HBV infection. Methods A retrospective analysis was performed for the clinical data of 330 HBeAg-positive patients with chronic HBV infection who were hospitalized in Affiliated Hospital of Yan’an University from October 2013 to August 2018 and underwent liver biopsy, and according to liver pathological results, these patients were divided into mild liver fibrosis group (F0-F1) and significant liver fibrosis group (F2-F4). The t-test or the Mann-Whitney U test was used for comparison of continuous data between two groups, and the chi-square test was used for comparison of categorical data between two groups. Univariate and multivariate analyses were performed to screen out the indices for the diagnosis of significant liver fibrosis, and the receiver operating characteristic (ROC) curve was plotted for these indices to evaluate their value in the diagnosis of significant liver fibrosis. Results Of all 330 patients, 245 had mild liver fibrosis and 85 had significant liver fibrosis. There were significant differences between the two groups in HBV DNA, HBsAg, HBeAg, HBcAb, alanine aminotransferase, aspartate aminotransferase, total bilirubin, and LSM (all P＜0.05). The multivariate analysis showed that HBsAg and LSM were independent risk factors for significant liver fibrosis (both P＜0.05). The ROC curve analysis showed that only LSM had a diagnostic value, with an area under the ROC curve of 0.744 (95% confidence interval: 0.680-0.808). At the optimal cut-off value of 6.15 kPa, LSM had a sensitivity of 62.4%, a specificity of 76.3%, an accuracy of 72.1%, a positive predictive value of 72.5%, and a negative predictive value of 67.0% in predicting significant liver fibrosis. ConclusionLSM has a good value in predicting significant liver fibrosis in HBeAg-positive patients with chronic HBV infection. [ABSTRACT FROM AUTHOR]

Copyright of Acta Edulis Fungi is the property of Acta Edulis Fungi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Edulis Fungi is the property of Acta Edulis Fungi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect of pharmacotherapy on decompensated liver function in children with hepatolenticular degeneration. Methods Three children with “liver cirrhosis and decompensated liver function” as the onset of hepatolenticular degeneration who were admitted to Jinshan Hospital Affiliated to Fudan University from August 1, 2015 to August 1, 2016 were enrolled, and ATP7B gene sequencing was performed to make a confirmed diagnosis. Clinical outcome was recorded. Results Compound heterozygous mutation of the ATP78 gene was detected in the three children. After comprehensive medical treatment, all children had improvements in hypoproteinemia and coagulation function, and two children had a reduced Child-Pugh score. Conclusion Hepatolenticular degeneration should be considered for children with unexplained abnormal liver function and even liver cirrhosis, and early diagnosis and timely pharmacotherapy can reduce the need for liver transplantation. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the value of blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI) in the assessment of renal oxygenation of patients with type 2 diabetes mellitus (T2DM). Methods From April 2014 to October 2015, kidney scans were conducted in eighteen patients with T2DM and twenty-two healthy controls with a Philips 3.0T scanner by using a BOLD-MRI sequence. The medullary and cortical apparent relaxation rate(R2*)values were measured in both groups. Paired samples t-test and independent samples t-test were used in data comparison within or between groups. The correlation between the renal glomerular filtration rate estimated using cystatin C(CysC-GFR) and the R2* values was analyzed by Pearson correlation coefficient analysis. Results The medullary R2* values were significantly higher than those of cortex in both groups (t=21.5, 21.1,both P<0.01). The cortex R2* values in patients with T2DM and healthy controls were (15.3±1.9) and (15.0±1.7) 1/s respectively, and there was no significant differences between two groups (t=0.7, P>0.05). The medullary R2* values in the patients with T2DM and healthy controls were (38.1±4.1) and (29.6±2.7) 1/s respectively, it was significantly higher in the type 2 diabetic patients than that in healthy controls (t=8.0, P<0.01). Medullary R2* value had a high sensitivity (83.33%) and specificity (100%) in identifying patients with T2DM with an area under the receiver operating characteristic curve of 0.965, and the best testing threshold was 34.1 1/s. The medullary R2* value was found positively correlated with CysC-GFR level in patients with T2DM (r=0.7, P<0.01), but no correlation was found between the cortical R2* value and CysC-GFR (r=0.1, P>0.05). Conclusion BOLD-MRI can detect and assess the renal medullary hypoxia in patients with T2DM at the early stage, and medullary R2* value may reflect the changes of renal function. [ABSTRACT FROM AUTHOR]