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Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective：To investigate the effect of age on the clinical outcomes of in vitro fertilization - embryo transfer (IVF-ET). Methods: The clinical data of 4 512 infertile women who received IVF-ET in our Reproductive Medicine Center from January 2013 to July 2017 was analyzed retrospectively. All subjects were divided into six groups: younger than 35 years (3 619 cases, 11 patients were lost in follow-up), aged 35-37 years (479 cases), aged 38-40 years (262 cases), aged 41-42 years (90 cases), aged 43-44 years (39 cases), and older than 44 years (23 cases). The clinical pregnancy rate, first -trimester abortion rate, late abortion rate, ectopic pregnancy rate and live birth rate were compared among six groups. Results: There were decreases with age in the clinical pregnancy rate (P＜0.000 1), while the clinical pregnancy rate was best in the group of ＜35 years (54.42%). Meanwhile，the early abortion rate was increased significantly with age, especially in the women over 35 years (P＜0.01), and almost reached to 40% in the women more than 40 years. The live birth rate was decreased with age (P＜0.000 1), and this rate was 0 in those women aged more than 44 years. Conclusions: Age is a key factor related to the clinical outcomes of IVF-ET. The early intervention treatment should be advocated in those infertile women aged over 38 years because of the poor clinical outcomes. [ABSTRACT FROM AUTHOR]