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• A total of 58 STRs and 94 iiSNPs were typed in Nigerians residing in Guangzhou • Both targeted region variations and flanking region variations were analyzed • The combined match probability of the 27 A-STRs was low at 9.06 × 10-38 African populations exhibit extensive linguistic and cultural diversity but are less studied from a population genetic standpoint. Although much genetic data on admixed African individuals, such as African Americans, have been published, genetic polymorphism data, especially that based on sequence-based typing, are still insufficient in indigenous Africans. In this study, we examined the genetic diversity of 85 Nigerians residing in Guangzhou, China. Forensically relevant genetic markers, including autosomal short tandem repeats (A-STRs), X-chromosomal STRs (X-STRs), Y-chromosomal STRs (Y-STRs), and identity-informative single nucleotide polymorphisms (iiSNPs) were genotyped to uncover the genetic polymorphisms of this population. Sequence-based allelic variations were observed in 22 A-STRs, ten Y-STRs, and four X-STRs. Using massively parallel sequencing (MPS), the allele number increased from 475 length-based alleles to 683 sequence-based alleles. Compared to other populations, the overall observed heterozygosity of the 27 A-STRs was the highest in Nigerians, which reflected the higher genetic diversity of this population. The combined match probability of the 27 A-STRs was low at 9.06 × 10-38. When both A-STRs and iiSNPs were considered, the cumulative discrimination power, and combined power of exclusion for duo and trio paternity testing was 1–2.97 × 10-57, 1–2.20 × 10-10 and 1–4.61 × 10-17, respectively, which demonstrated that the STRs and SNPs analyzed here can be applied to forensic investigations. In summary, this study uncovers the genetic features of the Nigerian population and provides valuable frequency data for forensic applications. [ABSTRACT FROM AUTHOR]

In view of the characteristics of heavy metal and antibiotic compound pollution in the Pearl River Basin in Guangzhou. More scientifically modified cellulose, named HVUC, is characterized by multiple hydrophilic groups, long chains and large space and displays highly efficient adsorption of both Cd and sulfamethoxazole (SMZ) and good adaptability in a wide pH range and at high ion strength. Furthermore, the coadsorption mechanism was elaborated from multiple angles. Multiple adsorption experiments explained the competition and synergy effect in the adsorption process. The electrostatic potential maps indicated that HVUC had advantageous adsorption sites for both Cd and SMZ and that electrostatic interactions had the greatest impact on the adsorption of Cd and SMZ. The electron density and differential charge density images proved that Cd more easily overlapped electron clouds and transferred electrons with HVUC and that SMZ- and could act as a bridge for SMZ-. The equilibrium configuration indicated that the formation of Cd-SMZ- complexes led to the bending and folding of SMZ-, which was not conducive to overall adsorption when SMZ- was close to HVUC and could lead to the release of SMZ- when Cd was close to HVUC, which confirmed the proposed mechanism of complexation-decomplexation-complexation. [Display omitted] • Cellulose is characterized by multiple hydrophilic groups, long chains and large space. • Electrostatic interactions had the greatest impact on the adsorption of Cd and SMZ. • HVUC had advantageous adsorption sites for both Cd and SMZ. • Cd more easily overlapped electron clouds and transferred electrons with HVUC and SMZ-. • The formation of Cd-SMZ- complexes led to the bending and folding of SMZ-. [ABSTRACT FROM AUTHOR]