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This article evaluates the impact of upstream water withdrawal on downstream land use and livelihood changes in the Teesta River basin, using a combination of geospatial and social data. Results show that water bodies gradually decreased, indicating a low volume of water discharge from upstream of the Teesta River basin due to the construction of several barrages. During the study period, a significant change in the area of water bodies was observed between 2012 and 2016, from 881 to 1123 Ha, respectively. The cropland area increased because farmers changed their cropping practice due to water scarcity and floods. Trend analyses of riverbank erosion and accretion patterns suggest an increase in accretion rates compared to the rate of riverbank erosion. A household survey was conducted using a self-administered questionnaire where 450 respondents have participated (farmers: 200 and fishermen: 250). Survey results show that most of the farmers (65.5%) and fishermen (76.8%) think that the construction of upstream barrages caused harm to them. The majority of farmers and fishermen feel water scarcity, mainly in the dry season. We found that a large number of participants in the study area are willing to change their occupations. Furthermore, participants observed that many local people are migrating or willing to migrate to other places nowadays. Our study also found that farmers who face water scarcity in their area are more likely to change their location than their counterparts, while those who face problems in their cultivation are less likely to move. On the other hand, upstream barrages, fishing effects, and getting support in crisis significantly predict fishermen's occupation changes. We believe our results provide essential information on the significance of transboundary water-sharing treaties, sustainable water resource management, and planning. [ABSTRACT FROM AUTHOR]

This research was carried out to investigate the thrombolytic effects of the methanolic extracts of five Bangladeshi plants. Phytochemical metabolites of those plants have been identified to elucidate whether the plant-derived metabolites are linked with the thrombolytic effects. Potential computer aided models were adopted in this study to find out a structure-function correlation between the phytochemical constituents and thrombolytic effects using the secondary metabolites as ligands and tissue plasminogen activator (t-PA) as receptor for the best fit ligand-receptor interaction. [ABSTRACT FROM AUTHOR]