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Purpose. To introduce a clinical sign on spectral domain optical coherence tomography (SDOCT), which may indicate high risk for full-thickness macular hole formation after internal limiting membrane (ILM) peeling. Methods. The preoperative SDOCT images of two patients—one with multilaminar hemorrhage from ruptured retinal artery macroaneurysm and one with serous retinal detachment and severe macular schisis from optic pit maculopathy—who developed full-thickness macular hole (FTMH) after ILM peeling were evaluated retrospectively. Results. On the preoperative SDOCT images of both patients there was a thin bridge of tissue on either side of the foveal center with an outer retinal defect. The photoreceptors were displaced laterally away from the foveal center to create an “omega-” shaped configuration of the remaining tissue. Conclusion. “Omega-” shaped configuration on SDOCT may represent a higher risk of FTMH following ILM peeling. Vitreoretinal surgeons may wish to consider this sign in the process of their surgical decision making. [ABSTRACT FROM AUTHOR]

To determine macular thickness in 3- to 6-year-old children who were born preterm compared with age-matched controls born at term. Children 36-72 months of age born ≤34 weeks and age-matched control children born at term were included in this prospective case–control study. Macular thickness measurements obtained using spectral domain optical coherence tomography were compared between groups and correlations of macular thickness were investigated in the preterm group. A total of 45 preterm children (median age, 57.7 months) and 44 controls (median, 56.1 months) were included. Central macula thickness (CMT) was significantly higher (P = 0.010) and perifoveal thickness was significantly lower (P = 0.029) in the preterm group compared with the control group. Moderate negative correlations of CMT with gestational age and birth weight were found in the preterm group. Best-corrected visual acuity was similar between groups and was not correlated with CMT in the preterm group. No significant difference in macular thickness was found between subjects who had retinopathy of prematurity and those who did not. Compared with controls, children in the preterm group had thicker retinas at the central macula and thinner perifoveal retinas. These subtle alterations were not correlated with visual acuity and may be considered a reflection of prematurity. [ABSTRACT FROM AUTHOR]