21 results on '"Mitral insufficiency"'
Search Results
2. Decade-long mitral valve surgery trends and rheumatic heart disease: a review of mitral valve surgery in a large Chinese cardiovascular center.
- Author
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Jiao Y, Luo T, Meng X, and Wang J
- Subjects
- China epidemiology, Humans, Mitral Valve surgery, Retrospective Studies, Cardiac Surgical Procedures, Heart Valve Diseases epidemiology, Heart Valve Diseases surgery, Rheumatic Heart Disease epidemiology, Rheumatic Heart Disease surgery
- Abstract
Background: Despite being one of the few chronic secondary heart diseases that can be prevented, current epidemiological data on rheumatic heart disease (RHD) in China are unavailable. This study examined mitral valve (MV) surgery trends in a large Chinese cardiovascular center over the last 10 years and provided insight into the distribution of RHDs and their changes., Methods: Medical records of patients who underwent cardiac surgery, MV surgery, and MV surgery for rheumatic MV (rMV) disease at Beijing Anzhen Hospital between January 2010 and December 2019 were retrospectively reviewed. Patients' demographic and clinical characteristics were statistically analyzed among age groups., Results: Overall, 7,736 patients underwent rMV surgery and 87.5% were aged 40-70 years. The proportion of patients aged >60 years increased annually (P<0.05), and the proportion of patients in all other age groups decreased. The proportion of patients with rMV diseases among those with cardiac or mitral valve diseases decreased each year, but the absolute number of patients with rMV disease remained stable. Approximately 90% of patients who underwent rMV surgery were from northern China. The incidence of rMV disease among patients with mitral valve disease moderately correlated with the per capita gross regional product (Per-GRP), an indicator of living standards (r=-0.517, P<0.05)., Conclusions: RHD still exists in northern China and requires adequate resources for its management. The number of older patients with rMV disease presents a challenge for mitral valve surgery.
- Published
- 2022
- Full Text
- View/download PDF
3. Evaluation of the diagnostic value of the renal resistive index as a marker of the subclinical development of cardiorenal syndrome in MMVD dogs.
- Author
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Szczepankiewicz B, Pasławska U, Siwińska N, Plens K, and Pasławski R
- Subjects
- Animals, Cardio-Renal Syndrome blood, Cardio-Renal Syndrome diagnostic imaging, Dogs, Female, Heart diagnostic imaging, Heart Valve Diseases blood, Heart Valve Diseases diagnostic imaging, Kidney diagnostic imaging, Logistic Models, Male, Mitral Valve diagnostic imaging, Ultrasonography, Biomarkers metabolism, Cardio-Renal Syndrome diagnosis, Cardio-Renal Syndrome veterinary, Heart Valve Diseases diagnosis, Heart Valve Diseases veterinary, Kidney pathology, Mitral Valve pathology
- Abstract
Introduction: Myxomatous mitral valve disease (MMVD) in dogs inevitably causes renal dysfunction. These interactions are known as the cardiorenal syndrome (CRS). The main aims of the study were to evaluate whether renal resistive index (RRI) may be useful as a non-invasive marker in subclinical stage of kidney injury in dogs with MMVD and to compare RRI with SDMA and Cyst C., Methods: Forty-four dogs were divided into two groups: control-15 healthy dogs and the heart group-29 dogs with MMVD (ACVIM class Cc). Study protocol included: anamnesis, clinical examination, electrocardiography, echocardiography, chest radiography, abdominal ultrasonography with measurements of the renal resistive index (RRI), urine, and blood analysis., Results: The RRI in the heart group was significantly higher 0.725 ± 0.035 versus control group 0.665 ± 0.028 ( p < 0.00085). The RRI cut-off point in dogs with stable chronic heart failure (CHF) under 8 years is 0.775, in older 0.64. RRI was similar in MMVD dogs treated with ACE-I + furosemide and dogs treated ACE-I + torasemide + pimobendan + spironolactone. There was no correlation between RRI and SDMA or Cyst C., Conclusion: RRI is more sensitive than creatinine, SDMA and Cyst C to reveal kidney injury in MMVD dogs class Cc younger than 8 years.
- Published
- 2021
- Full Text
- View/download PDF
4. Impact of chronic kidney disease on long-term outcome of patients with valvular heart defects.
- Author
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Kuźma Ł, Małyszko J, Bachórzewska-Gajewska H, Niwińska MM, Kurasz A, Zalewska-Adamiec M, Kożuch M, and Dobrzycki S
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Prognosis, Severity of Illness Index, Time Factors, Heart Valve Diseases complications, Heart Valve Diseases mortality, Renal Insufficiency, Chronic complications, Renal Insufficiency, Chronic mortality
- Abstract
Introduction: Valvular heart diseases (VHD) are becoming a significant problem in the Polish population. Coexistence of chronic kidney disease (CKD) in patients with VHD increases the risk of death and affects further therapeutic strategy., Aim: Analysis impact of CKD on long-term prognosis in patients with VHD., Material and Methods: The inclusion criteria were met by 1025 patients with moderate and severe VHD. Mean observation time was 2528 ± 1454 days., Results: The average age of the studied population was 66.75 (SD = 10.34), male gender was dominant 56% (N = 579). Severe aortic valve stenosis (AVS) occurred in 28.2%, severe mitral valve insufficiency (MVI) in 20%. CKD occurred in 37.1% (N = 380) patients mostly with mitral stenosis (50%, N = 16) and those with severe MVI (44.8%, N = 94). During the observational period, 52.7% (N = 540) deaths were noted. Increased risk of mortality was associated mostly with age (OR: 1.02, 95% CI: 1.00-1.03, p < 0.001), creatinine (OR:1.27, 95% CI: 1.12-1.43, p < 0.001), CKD (OR: 1.30, 95% CI: 1.17-1.44, p < 0.001), reduced ejection fraction (EF) (OR: 0.98, 95% CI: 0.97-0.99, p = 0.01) and coexisting of AVS (OR: 1.19, 95% CI: 1.04-1.35, p = 0.01)., Conclusions: Mitral valve defects more often than aortic valve defects coexist with chronic kidney disease. Regardless of the stage, chronic kidney disease is an additional factor affecting the prognosis in patients with heart defects. Factors increasing the risk of death were age, creatinine concentration and reduced EF. The monitoring of renal function in patients with VHD should be crucial as well as the implementation of treatment at an early stage.
- Published
- 2020
- Full Text
- View/download PDF
5. The association between systemic lupus erythematosus and valvular heart disease: an extensive data analysis.
- Author
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Watad A, Tiosano S, Grysman N, Comaneshter D, Cohen AD, Shoenfeld Y, and Amital H
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- Adult, Aged, Antibodies, Antiphospholipid immunology, Antiphospholipid Syndrome immunology, Aortic Valve Insufficiency epidemiology, Aortic Valve Insufficiency immunology, Aortic Valve Stenosis epidemiology, Aortic Valve Stenosis immunology, Case-Control Studies, Cross-Sectional Studies, Female, Heart Valve Diseases immunology, Humans, Hypertension epidemiology, Israel epidemiology, Logistic Models, Lupus Erythematosus, Systemic immunology, Male, Middle Aged, Mitral Valve Insufficiency epidemiology, Mitral Valve Insufficiency immunology, Mitral Valve Stenosis epidemiology, Mitral Valve Stenosis immunology, Risk Factors, Sex Factors, Antiphospholipid Syndrome epidemiology, Heart Valve Diseases epidemiology, Lupus Erythematosus, Systemic epidemiology
- Abstract
Background: Association between antiphospholipid syndrome in systemic lupus erythematosus (SLE) and valvular heart disease (VHD) is well reported, but relatively few studies have been carried out to establish the linkage between VHD and SLE itself. We aimed to investigate link between VHD and SLE and to evaluate the association of diverse factors with VHD among these patients in a large-scale population-based study., Materials and Methods: We used the databases of the largest state-mandated health service organization in Israel. All SLE patients were included (n = 5018) as well as their age and sex-matched controls (n = 25 090), creating a cross-sectional population-based study. Medical records of all subjects were analysed for documented VHD and the presence of antiphospholipid antibodies (aPLs). A logistic regression model was carried out to evaluate the diverse factors including SLE and aPLs as independent risk factors for VHD., Results: Valvular heart disease were found to be more frequent among SLE group when compared to controls (aortic stenosis, 1·08% vs. 0·35% respectively, P < 0·001; aortic insufficiency, 1·32% vs. 0·29% respectively, P < 0·001; mitral stenosis, 0·74% vs. 0·21% respectively, P < 0·001; mitral insufficiency, 1·91% vs. 0·39% respectively, P < 0·001). Male sex, hypertension, aPLs and SLE were found to be significant independent risk factors for VHD., Conclusion: All VHD are more prevalent among SLE patients when compared to controls. SLE and aPLs are independent risk factor for VHD (OR of 2·46 and 1·7, respectively). Physicians must be aware of such significant association, and routine echocardiography should be considered in SLE patients regardless of their aPL status., (© 2017 Stichting European Society for Clinical Investigation Journal Foundation.)
- Published
- 2017
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6. The role of cardiac magnetic resonance in valvular heart disease.
- Author
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Lopez-Mattei JC and Shah DJ
- Subjects
- Humans, Reproducibility of Results, Severity of Illness Index, Heart Valve Diseases diagnosis, Heart Valves pathology, Magnetic Resonance Imaging, Cine methods
- Abstract
The prevalence of valvular heart disease is increasing as the population ages. In diagnosing individuals with valve disease, echocardiography is the primary imaging modality used by clinicians both for initial assessment and for longitudinal evaluation. However, in some cases cardiovascular magnetic resonance has become a viable alternative in that it can obtain imaging data in any plane prescribed by the scan operator, which makes it ideal for accurate investigation of all cardiac valves: aortic, mitral, pulmonic, and tricuspid. In addition, CMR for valve assessment is noninvasive, free of ionizing radiation, and in most instances does not require contrast administration. The objectives of a comprehensive CMR study for evaluating valvular heart disease are threefold: (1) to provide insight into the mechanism of the valvular lesion (via anatomic assessment), (2) to quantify the severity of the valvular lesion, and (3) to discern the consequences of the valvular lesion.
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- 2013
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7. Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)
- Published
- 2024
8. One-Year Outcomes of Transseptal Mitral Valve-in-Valve in Intermediate Surgical Risk Patients.
- Author
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Malaisrie, S. Chris, Guerrero, Mayra, Davidson, Charles, Williams, Mathew, de Brito, Fábio Sândoli, Abizaid, Alexandre, Shah, Pinak, Tsuyoshi Kaneko, Poon, Karl, Levisay, Justin, Xiao Yu, Pibarot, Philippe, Hahn, Rebecca T., Blanke, Philipp, Leon, Martin B., Mack, Michael J., and Zajarias, Alan
- Abstract
BACKGROUND: Transcatheter mitral valve-in-valve replacement offers a less-invasive alternative for high-risk patients with bioprosthetic valve failure. Limited experience exists in intermediate-risk patients. We aim to evaluate 1-year outcomes of the PARTNER 3 mitral valve-in-valve study. METHODS: This prospective, single-arm, multicenter study enrolled symptomatic patients with a failing mitral bioprosthesis demonstrating greater than or equal to moderate stenosis and regurgitation and Society of Thoracic Surgeons score ≥3% and <8%. A balloon-expandable transcatheter heart valve (SAPIEN 3, Edwards Lifesciences) was used via a transeptal approach. The primary end point was the composite of all-cause mortality and stroke at 1 year. RESULTS: A total of 50 patients from 12 sites underwent mitral valve-in-valve from 2018 to 2021. The mean age was 70.1±9.7 years, mean Society of Thoracic Surgeons score was 4.1%±1.6%, and 54% were female. There were no primary end point events (mortality or stroke) through 1 year, and no left-ventricular outflow tract obstruction, endocarditis, or mitral valve reintervention was reported. Six patients (12%) required rehospitalization, including heart failure (n=2), minor procedural side effects (n=2), and valve thrombosis (n=2; both resolved with anticoagulation). An additional valve thrombosis was associated with no significant clinical sequelae. From baseline to 1 year, all subjects with available data had none/trace or mild (grade 1+) mitral regurgitation and the New York Heart Association class improved in 87.2% (41/47) of patients. CONCLUSIONS: Mitral valve-in-valve with a balloon-expandable valve via transseptal approach in intermediate-risk patients was associated with improved symptoms and quality of life, adequate transcatheter valve performance, and no mortality or stroke at 1-year follow-up. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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9. Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort II: Structural Heart Interventions (PLUTO-II) (PLUTO-II)
- Author
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Nicolas van Mieghem, prof. dr. N.M. Van Mieghem
- Published
- 2024
10. Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
- Published
- 2023
11. Transcatheter Mitral Valve Repair Versus Transcatheter Mitral Valve Replacement in Patients with Mitral insufficiency.
- Author
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Wang, Xiqiang, Fan, Xiude, Ma, Yanpeng, Zhu, Ling, Wang, Ting, Liu, Jing, Liu, Chengfeng, Hayashi, Tomohiro, Guan, Gongchang, Pan, Shuo, Liu, Zhongwei, and Wang, Junkui
- Subjects
- *
MITRAL valve insufficiency , *MITRAL valve , *HEART valve diseases , *ACUTE kidney failure , *BLOOD transfusion reaction - Abstract
Mitral regurgitation (MR) is the most prevalent form of valvular heart disease. Transcatheter mitral valve repair (TMVr) and transcatheter mitral valve replacement (TMVR) have recently emerged as alternatives to open heart surgical repair or replacement. However, studies on the comparative outcomes of TMVr and TMVR are limited. This study aims to compare the demographics, complications and outcomes of TMVr and TMVR based on a real-world investigation of the National Inpatient Sample (NIS) database. From 2016–2018 in the NIS database, a total of 210 and 3370 patients who underwent TMVR and TMVr, respectively, were selected. The mean age of the patients was 75.99 years (TMVr) and 69.6 years (TMVR) (p <0.01). The mortality of patients who received TMVR was higher compared to that of patients who were treated with TMVr (8.1 vs. 1.9%, p <0.01). The patients who underwent TMVR were more likely to suffer perioperative complications including blood transfusions (16.2 vs. 5.0%, p <0.01) and acute kidney injury (22.9 vs. 13.3%, p <0.01). The average cost of treatment was higher (USD $278864 vs. USD $216845, p <0.01), and the average duration of hospitalization was longer (8.73 vs. 4.17 d, p <0.01) for TMVR compared to TMVr. When taking into account perioperative comorbidities and other factors, TMVR was associated with a worse adjusted in-hospital mortality (odds ratio [OR], 3.307 [95% CI, 1.533–7.136]; p <0.01). TMVr is associated with lower mortality, peri-procedural morbidity, and resource use compared to TMVR. A patient-centered approach can help guide decision-making about the choice of intervention for the individual patient and more studies evaluating the long-term outcomes and durability of TMVR are needed at present. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
12. Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)
- Published
- 2016
13. A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)
- Published
- 2016
14. Acute coronary syndromes and atherosclerotic plaque burden distribution in coronary arteries among patients with valvular heart disease (BIA-WAD registry).
- Author
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Kuźma, Łukasz, Bachórzewska-Gajewska, Hanna, Kożuch, Marcin, Struniawski, Krzysztof, Pogorzelski, Szymon, Hirnle, Tomasz, and Dobrzycki, Sławomir
- Subjects
- *
HEART valve diseases , *ACUTE coronary syndrome , *ATHEROSCLEROTIC plaque , *CARDIAC patients , *MITRAL valve insufficiency , *CORONARY arteries - Abstract
Introduction: Valvular heart diseases (VHD) are a significant problem in the Polish population. Coexistence of coronary artery disease (CAD) in patients with VHD increases the risk of death and affects the further therapeutic strategy. Aim: Analysis of atherosclerotic plaque burden distribution in coronary arteries and long-term prognosis among patients with VHD. Material and methods: Inclusion criteria were met by 1025 patients with moderate and severe VHD. Mean observation time was 2528 ±1454 days. Results: Severe aortic valve stenosis (AVS) occurred in 28.2%, severe mitral valve insufficiency (MVI) in 20%. CAD with severe angiographic stenoses was noted in 42.3% (n = 434). Among patients with severe MVI, CAD was noted in 47.1% of cases, and prior acute coronary syndromes (ACS) in 27.1% of patients (n = 58). In severe AVS patients, significant angiographic atherosclerotic changes were observed in 29.6% (n = 86), and prior ACS in 7.6% (n = 22) of patients. During the observation 52.7% of patients died, including 62.9% of patients with severe MVI and 51.6% of those with severe AVS. Age (OR = 1.038; 95% CI: 1.005-1.072; p = 0.022) and coexisting aortic valve insufficiency (AVI) (OR = 2.39, 95% CI: 5.370-11.065, p = 0.035) increased the mortality rate. Conclusions: Severe AVS is starting to be the most prevalent VHD. CAD is one of the most significant factors deteriorating prognosis of patients with VHD. AVI and age were significant risk factors for mortality. The worst prognosis was observed in severe MVI, which may result from more frequent occurrence of CAD in this group. A lesser burden of CAD and ACS in the group of patients with severe AVS did not affect survival. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
15. Impact of chronic kidney disease on long-term outcome of patients with valvular heart defects
- Author
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Hanna Bachórzewska-Gajewska, Małgorzata Zalewska-Adamiec, Jolanta Malyszko, Marta Maria Niwińska, Sławomir Dobrzycki, Anna Kurasz, Marcin Kożuch, and Łukasz Kuźma
- Subjects
Nephrology ,Male ,medicine.medical_specialty ,Time Factors ,Urology ,Population ,Heart Valve Diseases ,Renal function ,030204 cardiovascular system & hematology ,Severity of Illness Index ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Mitral valve ,Chronic kidney disease ,medicine ,Nephrology - Original Paper ,Humans ,030212 general & internal medicine ,Renal Insufficiency, Chronic ,education ,Aged ,education.field_of_study ,Ejection fraction ,business.industry ,Aortic stenosis ,valvular heart disease ,Middle Aged ,medicine.disease ,Prognosis ,Valvular heart disease ,medicine.anatomical_structure ,Aortic valve stenosis ,Cardiology ,Female ,Glomerular filtration rate ,business ,Mitral insufficiency ,Kidney disease - Abstract
Introduction Valvular heart diseases (VHD) are becoming a significant problem in the Polish population. Coexistence of chronic kidney disease (CKD) in patients with VHD increases the risk of death and affects further therapeutic strategy. Aim Analysis impact of CKD on long-term prognosis in patients with VHD. Material and methods The inclusion criteria were met by 1025 patients with moderate and severe VHD. Mean observation time was 2528 ± 1454 days. Results The average age of the studied population was 66.75 (SD = 10.34), male gender was dominant 56% (N = 579). Severe aortic valve stenosis (AVS) occurred in 28.2%, severe mitral valve insufficiency (MVI) in 20%. CKD occurred in 37.1% (N = 380) patients mostly with mitral stenosis (50%, N = 16) and those with severe MVI (44.8%, N = 94). During the observational period, 52.7% (N = 540) deaths were noted. Increased risk of mortality was associated mostly with age (OR: 1.02, 95% CI: 1.00–1.03, p p p p = 0.01) and coexisting of AVS (OR: 1.19, 95% CI: 1.04–1.35, p = 0.01). Conclusions Mitral valve defects more often than aortic valve defects coexist with chronic kidney disease. Regardless of the stage, chronic kidney disease is an additional factor affecting the prognosis in patients with heart defects. Factors increasing the risk of death were age, creatinine concentration and reduced EF. The monitoring of renal function in patients with VHD should be crucial as well as the implementation of treatment at an early stage.
- Published
- 2020
16. The Effect of Patient Prosthesis Mismatch on Functional Mitral Regurgitation in Patients with Mechanical Aortic Valve Replacement
- Author
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Sinan Sabit Kocabeyoglu, Sertan Özyalçın, Kerem M. Vural, and Mehmet Emir Erol
- Subjects
lcsh:Diseases of the circulatory (Cardiovascular) system ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Mechanical Aortic Valve ,aortic valve stenosis ,medicine.disease ,heart valve diseases ,Prosthesis ,mitral insufficiency ,lcsh:RC666-701 ,Aortic valve stenosis ,Internal medicine ,cardiovascular system ,medicine ,Cardiology ,In patient ,business ,Functional mitral regurgitation - Abstract
Introduction: The aim of this study was to investigate the effects of patient prosthesis mismatch on functional mitral regurgitation after mechanical aortic valve replacement. Patients and Methods: Total 59 patients were enrolled. All the echocardiographic assessments were performed by a single cardiologist. The patients were divided into two subgroups as per the presence of patient prosthesis mismatch. Group 1 comprised patients with mismatch, and group 2 included those without mismatch. Results: There were no significant differences between the two groups in terms of postoperative mitral regurgitation development, postoperative left ventricular mass regression, postoperative pulmonary arterial pressure, and postoperative functional capacity. Conclusion: Patient prosthesis mismatch is not a predictive factor for the development of functional mitral regurgitation after mechanical aortic valve replacement.
- Published
- 2020
17. A late presentation of congenital cardiac anomaly: Accessory chordae from the left atrium causing severe mitral regurgitation.
- Author
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D'Onghia, Giovanni, Martin, Marta, Mancini, Maria Teresa, Quintarelli, Silvia, Cozza, Adele, Guarracini, Fabrizio, and Bonmassari, Roberto
- Subjects
- *
CONGENITAL heart disease , *ECHOCARDIOGRAPHY , *HEART valve diseases , *MITRAL stenosis , *MITRAL valve diseases , *MITRAL valve insufficiency , *TRANSESOPHAGEAL echocardiography , *CALCINOSIS , *LEFT heart atrium , *DISEASE complications - Abstract
Mitral regurgitation secondary to accessory mitral valve (MV) chordae of the left atrium is an extremely rare congenital disease. A 85‐year‐old female (NYHA I–II) was hospitalized for investigations. An echocardiogram showed calcification of the MV with mild stenosis and moderate regurgitation. Transesophageal three‐dimensional echocardiogram revealed a band‐like structure extending from the distal third of the anterior wall of the left atrium to the MV. This accessory chordae determined severe systolic regurgitation and mild mitral stenosis. The patient was referred for consideration of cardiac surgery but was refused for comorbidities and anatomy. Usually aberrant chordae determinant valvulopathies are detected and treated at a much younger age. The delay of the symptoms could be explained in our case with the progressive growth and dilatation of the left atrium causing traction of the aberrant chord resulting in an increase in the leaflet prolapse and regurgitation. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
18. Percutaneous correction of acquired aortic stenosis and mitral insufficiency in adults
- Author
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Tron, C., Eltchaninoff, H., Bauer, F., Agatiello, C., Sebagh, L., Nercolini, D., Vochelet, F., and Cribier, A.
- Subjects
- *
AORTIC stenosis , *MITRAL valve insufficiency , *HEART valve diseases , *THERAPEUTICS ,WESTERN countries - Abstract
Aortic stenosis and mitral regurgitation are the most common valvular diseases in western countries. Surgical treatment, aortic valve replacement or mitral valve repair, is the treatment of choice. Innovative technologies could offer an alternative therapeutic option to the patients with increased operative risk. This article will report the early experience with these promising techniques as presented at the High-Tech 2004 meeting. [Copyright &y& Elsevier]
- Published
- 2004
- Full Text
- View/download PDF
19. Successful Repair of Aortic and Mitral Incompetence Induced by Methylsergide Maleate: Confirmation by Intraoperative Transesophageal Echocardiography.
- Author
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Joseph, Thomas, Tam, Stanley K.C., Kamat, Brinda R., and Mangion, Judy R.
- Subjects
- *
HEART valve diseases , *AORTIC valve - Abstract
Methylsergide maleate, an effective anti-migraine medication, has a well-documented association with left-sided cardiac valve dysfunction. Prior reports have described cardiac valve dysfunction in patients using methylsergide chronically for a minimum of 6 years, with surgical intervention consisting of valve replacement for patients with intractable congestive heart failure. We report a 51-year-old woman who developed severe mitral and aortic valvular dysfunction after taking methylsergide maleate for migraine headaches for a period of 19 months, and who subsequently underwent aortic and mitral valve repair with excellent short-term results. (ECHOCARDIOGRAPHY, Volume 20, April 2003). [ABSTRACT FROM AUTHOR]
- Published
- 2003
- Full Text
- View/download PDF
20. Evaluation of the diagnostic value of the renal resistive index as a marker of the subclinical development of cardiorenal syndrome in MMVD dogs
- Author
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Urszula Pasławska, Natalia Siwińska, Barbara Szczepankiewicz, Robert Pasławski, and Krzysztof Plens
- Subjects
Male ,kidney ,Medicine (General) ,medicine.medical_specialty ,RRI ,040301 veterinary sciences ,Heart Valve Diseases ,myxomatous mitral valve disease ,Cardiorenal syndrome ,Disease ,030204 cardiovascular system & hematology ,mitral insufficiency ,0403 veterinary science ,03 medical and health sciences ,Dogs ,R5-920 ,0302 clinical medicine ,Endocrinology ,Internal medicine ,Internal Medicine ,medicine ,Animals ,echocardiography ,Myxomatous mitral valve ,Subclinical infection ,Canine heart failure ,Kidney ,aldosterone ,Cardio-Renal Syndrome ,business.industry ,Heart ,ultrasonography ,04 agricultural and veterinary sciences ,medicine.disease ,Resistive index ,Logistic Models ,medicine.anatomical_structure ,Cardiology ,Mitral Valve ,Female ,Original Article ,Ultrasonography ,business ,human activities ,Biomarkers - Abstract
Introduction: Myxomatous mitral valve disease (MMVD) in dogs inevitably causes renal dysfunction. These interactions are known as the cardiorenal syndrome (CRS). The main aims of the study were to evaluate whether renal resistive index (RRI) may be useful as a non-invasive marker in subclinical stage of kidney injury in dogs with MMVD and to compare RRI with SDMA and Cyst C. Methods: Forty-four dogs were divided into two groups: control—15 healthy dogs and the heart group—29 dogs with MMVD (ACVIM class Cc). Study protocol included: anamnesis, clinical examination, electrocardiography, echocardiography, chest radiography, abdominal ultrasonography with measurements of the renal resistive index (RRI), urine, and blood analysis. Results: The RRI in the heart group was significantly higher 0.725 ± 0.035 versus control group 0.665 ± 0.028 ( p Conclusion: RRI is more sensitive than creatinine, SDMA and Cyst C to reveal kidney injury in MMVD dogs class Cc younger than 8 years.
- Published
- 2021
21. Biventricular myocardial noncompaction presenting with complete atrioventricular block
- Author
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Yildiz, Ali, Ozeke, Ozcan, Akyol, Selahattin, Demirbag, Recep, Yilmaz, Remzi, and Gur, Mustafa
- Subjects
- *
VENTRICULAR remodeling , *ATRIOVENTRICULAR node , *CARDIOMYOPATHIES , *HEART valve diseases , *HEART septum , *AORTIC valve insufficiency , *DIAGNOSIS - Abstract
Abstract: Noncompaction of ventricular myocardium has been recognized as a distinct form of cardiomyopathy with its own clinical presentation and natural history. Concomitance of either valvular pathologies or complete atrioventricular block with noncompaction of ventricular myocardium has rarely been reported. Herein, we present a case with biventricular noncompaction with significant interventricular septum involvement presenting with complete atrioventricular block, who was formerly diagnosed to have mitral and aortic insufficiency. [Copyright &y& Elsevier]
- Published
- 2009
- Full Text
- View/download PDF
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