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Your search keyword '"Niccoli, Giampaolo"' showing total 2 results
Start Over Author "Niccoli, Giampaolo" Topic drug-eluting stents Topic optical coherence tomography Topic percutaneous coronary intervention Publication Year Range Last 50 years
2 results on '"Niccoli, Giampaolo"'

1. Eroded versus ruptured plaques at the culprit site of STEMI: In vivo pathophysiological features and response to primary PCI

Author

Saia, Francesco, Komukai, Kenichi, Capodanno, Davide, Sirbu, Vasile, Musumeci, Giuseppe, Boccuzzi, Giacomo, Tarantini, Giuseppe, Fineschi, Massimo, Tumminello, Gabriele, Bernelli, Chiara, Niccoli, Giampaolo, Coccato, Micol, Bordoni, Barbara, Bezerra, Hiram, Biondi Zoccai, Giuseppe, Virmani, Renu, and Guagliumi, Giulio

Subjects
Male, Time Factors, Myocardial Infarction, Coronary Artery Disease, Prosthesis Design, Percutaneous Coronary Intervention, culprit plaque, Nuclear Medicine and Imaging, Humans, Everolimus, Prospective Studies, Tomography, Aged, Thrombectomy, Plaque, Atherosclerotic, Rupture, optical coherence tomography, Medicine (all), Coronary Thrombosis, Spontaneous, Cardiovascular Agents, Drug-Eluting Stents, Middle Aged, Coronary Vessels, Fibrosis, Immunohistochemistry, ST-segment elevation myocardial infarction, Treatment Outcome, Italy, Optical Coherence, plaque erosion, percutaneous coronary intervention, Biomarkers, Female, Inflammation Mediators, Rupture, Spontaneous, Tomography, Optical Coherence, Plaque, Atherosclerotic, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine, Radiology
Published
2015

2. Optical coherence tomography compared with fractional flow reserve guided approach in acute coronary syndromes: A propensity matched analysis.

Author

D'Ascenzo, Fabrizio, Iannaccone, Mario, De Filippo, Ovidio, Leone, Antonio Maria, Niccoli, Giampaolo, Zilio, Filippo, Ugo, Fabrizio, Cerrato, Enrico, Fineschi, Massimo, Mancone, Massimo, Rigattieri, Stefano, Amabile, Nicolas, Ferlini, Marco, Sardella, Gennaro, Cresti, Alberto, Barbero, Umberto, Motreff, Pascal, Colombo, Francesco, Colangelo, Salvatore, and Garbo, Roberto

Subjects
*ACUTE coronary syndrome, *PERCUTANEOUS coronary intervention, *MYOCARDIAL revascularization, *OPTICAL coherence tomography, *DRUG-eluting stents, *RANDOMIZED controlled trials
Abstract

Aim To compare in patients with ACS (acute coronary syndromes) a PCI (percutaneous coronary intervention) approach based on FFR (fractional flow reserve) vs. one based on OCT (optical coherence tomography). Methods and results Consecutive patients admitted for ACS and treated with a PCI approach based on OCT or on FFR (recruited in two different studies) were compared and matched with propensity score analysis. Target Lesion revascularization (TLR) was the primary end point, while major adverse cardiovascular events [MACEs defined as the composite of death from cardiac causes, non-fatal MI, clinically driven target vessel revascularization (TVR), or re-hospitalization due to unstable angina] were the secondary ones. Sub-group analysis was performed for patients with FFR/OCT performed on culprit lesions and not. 285 patients were enrolled in the OCT-guided group and 335 in the FFR-guided group, 197 for each being selected after propensity score. After 25 months (range: 7–39 months), OCT-guided group were exposed to lower incidence of TLR (4.1% vs. 14.2% p < 0.01) compared with FFR-guided group without impact on MACEs (14.2% vs. 14.2%, p = 1) or all-cause death (3.6% vs. 1.1%, p = 0.34). At Kaplan-Maier curve analysis for MACEs OCT-guided and FFR-guided groups showed similar outcomes (HR 1.19, CI 0.65–2.2, p = 0.54). Subgroup analysis on culprit and not culprit vessel demonstrated consistent results. Conclusions An OCT based approach in ACS patients offers a reduction in TLR when compared to a PCI-FFR driven. These findings should be confirmed in randomized controlled trial. [ABSTRACT FROM AUTHOR]

Published
2017
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