Search

Your search keyword '"Wilson, Carlene J."' showing total 3 results
Start Over Author "Wilson, Carlene J." Topic body mass index Publication Year Range Last 50 years
3 results on '"Wilson, Carlene J."'

1. Changes in endothelial function and depression scores are associated following long-term dietary intervention: A secondary analysis.

Author

Moran, Lisa J., Wilson, Carlene J., Buckley, Jonathan D., Noakes, Manny, Clifton, Peter M., and Brinkworth, Grant D.

Subjects
*ANXIETY diagnosis, *DIAGNOSIS of mental depression, *ENDOTHELIUM physiology, *OBESITY complications, *ACADEMIC medical centers, *BLOOD sugar, *BODY weight, *C-reactive protein, *DIET, *HIGH density lipoproteins, *HOMEOSTASIS, *INSULIN, *LOW density lipoproteins, *NUTRITION, *RESEARCH funding, *TRIGLYCERIDES, *DATA analysis, *MULTIPLE regression analysis, *SECONDARY analysis, *BODY mass index, *CROSS-sectional method, *DESCRIPTIVE statistics
Abstract

Objective: Cross-sectional studies show associations between depression and endothelial function (as measured by endothelium-dependent brachial artery flow-mediated dilatation [FMD]); but it is not known whether changes in these parameters are associated following dietary management. We have previously reported that compared with consumption of a high-carbohydrate (HC) diet, despite comparable weight loss, a very low-carbohydrate (LC diet) impaired FMD and increased depression. The purpose of this study was to conduct a secondary analysis to examine whether there was an association between changes in FMD and depression. Methods: Forty-seven overweightmen and women (body mass index 26-43 kg/m² and ages 24-64 y) completed a 12-mo randomized controlled trial during which participants consumed either an energy-restricted, isocaloric LC or HC diet. Weight, body composition, Homeostasis Assessment of Insulin Resistance (HOMA), depression (Beck Depression Inventory [BDI]), Anxiety (Spielberger State-Trait Anxiety Inventory [STAI]) and FMD were assessed before and after the intervention. This secondary analysis focused on multiple regression analysis of these parameters. Results: Changes in BDI were independently predicted by changes in FMD (β = -0.356; P = 0.026) but not by diet intervention assignment or changes in weight or HOMA. No variables were significant predictors of the change in STAI. Conclusions: Over time, impairments in FMD were independently associated with increased depression, independent of diet composition, or changes in weight and insulin resistance. This data supports a mechanistic association between depression and endothelial function, which may influence long-term health. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

2. Changes in endothelial function and depression scores are associated following long-term dietary intervention: a secondary analysis

Author

Jonathan D. Buckley, Lisa J. Moran, Manny Noakes, Peter M. Clifton, Carlene Wilson, Grant D. Brinkworth, Moran, Lisa J, Wilson, Carlene J, Buckley, Jonathan D, Noakes, Manny, Clifton, Peter M, and Brinkworth, Grant D

Subjects
Adult, Male, medicine.medical_specialty, Brachial Artery, Diet, Reducing, Endocrinology, Diabetes and Metabolism, Overweight, Anxiety, law.invention, Body Mass Index, Diet, Carbohydrate-Restricted, Young Adult, Insulin resistance, endothelial function, Randomized controlled trial, Weight loss, law, Internal medicine, Weight Loss, medicine, Dietary Carbohydrates, Humans, Depression (differential diagnoses), Nutrition and Dietetics, business.industry, Depression, Dietary management, Beck Depression Inventory, Feeding Behavior, Middle Aged, medicine.disease, Endocrinology, depression, Body Composition, Linear Models, Female, Endothelium, Vascular, medicine.symptom, Insulin Resistance, diet, business, Body mass index
Abstract

Objective: Cross-sectional studies show associations between depression and endothelial function (as measured by endothelium-dependent brachial artery flow-mediated dilatation [FMD]); but it is not known whether changes in these parameters are associated following dietary management. We have previously reported that compared with consumption of a high-carbohydrate (HC) diet, despite comparable weight loss, a very low-carbohydrate (LC diet) impaired FMD and increased depression. The purpose of this study was to conduct a secondary analysis to examine whether there was an association between changes in FMD and depression. Methods: Forty-seven overweight men and women (body mass index 26–43 kg/m2 and ages 24–64 y) completed a 12-mo randomized controlled trial during which participants consumed either an energy-restricted, isocaloric LC or HC diet. Weight, body composition, Homeostasis Assessment of Insulin Resistance (HOMA), depression (Beck Depression Inventory [BDI]), Anxiety (Spielberger State-Trait Anxiety Inventory [STAI]) and FMD were assessed before and after the intervention. This secondary analysis focused on multiple regression analysis of these parameters. Results: Changes in BDI were independently predicted by changes in FMD (β = −0.356; P = 0.026) but not by diet intervention assignment or changes in weight or HOMA. No variables were significant predictors of the change in STAI. Conclusions: Over time, impairments in FMD were independently associated with increased depression, independent of diet composition, or changes in weight and insulin resistance. This data supports a mechanistic association between depression and endothelial function, which may influence long-term health. Refereed/Peer-reviewed

Published
2013

3. Long-term Effects of a Very Low-Carbohydrate Diet and a Low-Fat Diet on Mood and Cognitive Function

Author

Manny Noakes, Peter M. Clifton, Grant D. Brinkworth, Jonathan D. Buckley, Carlene Wilson, Brinkworth, Grant D, Buckley, Jonathan D, Noakes, Manny, Clifton, Peter M, and Wilson, Carlene J

Subjects
Adult, Male, medicine.medical_specialty, Overweight, Profile of mood states, Risk Assessment, Body Mass Index, Diet, Carbohydrate-Restricted, Young Adult, Cognition, hypocaloric LF diet, Weight loss, mood state, Internal medicine, Weight Loss, Internal Medicine, medicine, Body Fat Distribution, Humans, Obesity, Diet, Fat-Restricted, Probability, obese, Mood Disorders, business.industry, Beck Depression Inventory, Middle Aged, medicine.disease, Affect, Treatment Outcome, Endocrinology, Mood, Patient Satisfaction, Multivariate Analysis, Anxiety, very low-carbohydrate (LC) diets, Female, women, weight loss, medicine.symptom, Cognition Disorders, Energy Intake, business, Body mass index, Follow-Up Studies
Abstract

Background: Very low-carbohydrate (LC) diets are often used to promote weight loss, but the long-term effects on psychological function remain unknown. Methods: A total of 106 overweight and obese participants (mean [SE] age, 50.0 [0.8] years; mean [SE] body mass index [calculated as weight in kilograms divided by height in meters squared], 33.7 [0.4]) were randomly assigned either to an energy-restricted (approximately 1433-1672 kcal [to convert to kilojoules, multiply by 4.186]), planned isocaloric, very low-carbohydrate, high-fat (LC) diet or to a high-carbohydrate, low-fat (LF) diet for 1 year. Changes in body weight, psychological mood and wellbeing (Profile of Mood States, Beck Depression Inventory, and Spielberger State Anxiety Inventory scores), and cognitive functioning (working memory and speed of processing) were assessed. Results: By 1 year, the overall mean (SE) weight loss was 13.7 (1.8) kg, with no significant difference between groups (P=.26). Over the course of the study, there were significant time x diet interactions for Spielberger State Anxiety Inventory, Beck Depression Inventory, and Profile of Mood States scores for total mood disturbance, anger-hostility, confusion-bewilderment, and depression-dejection (P

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results