13 results on '"Booij, Linda"'
Search Results
2. Developmental trajectories of eating disorder symptoms: A longitudinal study from early adolescence to young adulthood
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Breton, Édith, Dufour, Rachel, Côté, Sylvana M., Dubois, Lise, Vitaro, Frank, Boivin, Michel, Tremblay, Richard E., and Booij, Linda
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- 2022
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3. Childhood Overeating and Disordered Eating From Early Adolescence to Young Adulthood: A Longitudinal Study on the Mediating Role of BMI, Victimization and Desire for Thinness.
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Breton, Édith, Côté, Sylvana M., Dubois, Lise, Vitaro, Frank, Boivin, Michel, Tremblay, Richard E., and Booij, Linda
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AFFINITY groups ,STATISTICS ,HYPERPHAGIA ,CONFIDENCE intervals ,REGRESSION analysis ,LEANNESS ,SEX distribution ,RESEARCH funding ,DESCRIPTIVE statistics ,SOCIAL classes ,BODY mass index ,DATA analysis software ,LOGISTIC regression analysis ,ODDS ratio ,EATING disorders ,BULLYING ,BODY image in adolescence ,DISEASE complications ,CHILDREN ,ADOLESCENCE - Abstract
Eating disorders have early origins, and there could be a continuum between childhood eating behaviors, such as overeating, and long-term disordered eating, but this remains to be shown. BMI, desire for thinness and peer victimization could influence this continuum, but their interactions are unknown. To fill this gap, the study used data from the Quebec Longitudinal Study of Child Development (N = 1511; 52% girls), in which 30.9% of youth presented a trajectory associated with high disordered eating from 12 to 20 years. The results support an indirect association between overeating at age 5 and disordered eating trajectories, with different mediation processes observed between boys and girls. The findings underscore the importance of promoting healthy body images and eating behaviors among youths. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Eating disorders and substance use in adolescents: How substance users differ from nonsubstance users in an outpatient eating disorders treatment clinic.
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Kirkpatrick, Ryan, Booij, Linda, Vance, Ashleigh, Marshall, Brittany, Kanellos‐Sutton, Marina, Marchand, Patricia, and Khalid‐Khan, Sarosh
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TREATMENT of eating disorders , *SUBSTANCE abuse treatment , *SUBSTANCE abuse diagnosis , *BODY weight , *HEALTH status indicators , *OUTPATIENT services in hospitals , *SELF-mutilation , *PSYCHOLOGY of the sick , *TEENAGERS' conduct of life , *SYMPTOMS , *DRUG abusers , *RETROSPECTIVE studies , *SEVERITY of illness index , *PATIENT dropouts , *DESCRIPTIVE statistics , *ADOLESCENCE - Abstract
Objective: The relationship between eating disorders (EDs) and substance use (SU) has only been briefly described in literature using mainly adult populations. This study examined the prevalence and characteristics of SU among patients of an adolescent ED outpatient treatment program. Method: A retrospective chart analysis was conducted to determine and subsequently compare medical status, psychosocial factors, treatment course and outcome between patients with and without SU. Results: Over 60% of patients with SU status (n = 203) reported regularly consuming substances. 33.4% of substance users received a diagnosis involving purging behaviors compared to 5.9% of nonusers. Females composed 96.4% and 81.7% of users and nonusers, respectively. Users reported significantly more self‐harm (57.7% of users vs. 38.6% of nonusers) but did not differ significantly in terms of trauma (abuse or victimization; 48.3% of users vs. 44.9% of nonusers). The percentage of ideal body weight significantly improved throughout treatment and did not differ by SU with a mean increase of 5.29% (SD = 13.6) among nonusers compared to 5.45% (SD = 7.5) of users. While users and nonusers did not differ before and after treatment in ED severity, users were more likely than nonusers to drop‐out of treatment (41.5% of users vs. 25.2% of nonusers). Discussion: Adolescents with SU benefit from ED outpatient treatment as much as those without SU, however, users are more likely to drop‐out. Therefore, treatment should target these adolescents' emotional dysregulation to improve treatment compliance. Further research is necessary to determine the efficacy of such an approach. [ABSTRACT FROM AUTHOR]
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- 2019
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5. The Impact of the in utero and Early Postnatal Environments on Grey and White Matter Volume: A Study with Adolescent Monozygotic Twins.
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Levesque, Melissa L., Fahim, Cherine, Ismaylova, Elmira, Verner, Marie-Pier, Casey, Kevin F., Vitaro, Frank, Brendgen, Mara, Dionne, Ginette, Boivin, Michel, Tremblay, Richard E., and Booij, Linda
- Abstract
Prenatal and early postnatal adversities have been shown to be associated with brain development. However, we do not know how much of this association is confounded by genetics, nor whether the postnatal environment can moderate the impact of in utero adversity. This study used a monozygotic (MZ) twin design to assess (1) the association between birth weight (BW) and brain volume in adolescence, (2) the association between within-twin-pair BW discordance and brain volume discordance in adolescence, and (3) whether the association between BW and brain volume in adolescence is mediated or moderated by early negative maternal parenting behaviours. These associations were assessed in a sample of 108 MZ twins followed longitudinally since birth and scanned at age 15. The total grey matter (GM) and white matter (WM) volumes were obtained using the Diffeomorphic Anatomical Registration Through Exponentiated Lie Algebra (DARTEL) toolbox in the Statistical Parametric Mapping version 8 (SPM8). We found that the BW was significantly associated with the total GM and WM volumes, particularly in the superior frontal gyrus and thalamus. Within-twin-pair discordance in BW was also significantly associated with within-pair discordance in both the GM and the WM volumes, supporting the hypothesis that the specific in utero environment is associated with brain development independently of genetics. Early maternal hostile parenting behaviours and depressive symptoms were associated with total GM volume but not WM volume. Finally, greater early maternal hostility may moderate the association between the BW and GM volume in adolescence, since the positive association between the BW and total GM volume appeared stronger at higher levels of maternal hostility (trend). Together, these findings support the importance of the in utero and early environments for brain development. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
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- 2015
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6. Social cognition and depression in adolescent girls.
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Porter-Vignola, Elyse, Booij, Linda, Dansereau-Laberge, Ève Marie, Garel, Patricia, Bossé Chartier, Gabrielle, Seni, Anne G., Beauchamp, Miriam H., and Herba, Catherine M.
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Background and Objectives: Depression has been associated with alterations in social functioning. Decoding and understanding others' mental states and adaptive reasoning are important for social functioning. This study examined theory of mind (ToM) and socio-moral reasoning (SMR) in adolescent girls with and without depression. Within the depression group, we examined associations between relevant clinical features (depression severity, anxiety symptoms and borderline personality traits) and ToM and SMR.Methods: A cross-sectional study was conducted, whereby 43 adolescent girls (mean age = 16.19, SD = 1.24) meeting full or subthreshold criteria for depression and 40 adolescent girls (mean age = 15.44, SD = 1.24) with no psychiatric diagnosis were recruited. ToM was assessed using the Movie for the Assessment of Social Cognition; SMR was evaluated via the Socio-Moral Reasoning Aptitude Level task.Results: Analyses of covariance indicated that adolescents with depression did not differ from controls in ToM abilities but showed lower socio-maturity scores on the SMR task. This difference disappeared after controlling for the number of words used to justify responses. Amongst adolescents with depression, multiple linear regression analyses revealed that higher levels of borderline personality traits were associated with lower levels of mentalization (ToM task), and more severe depressive symptoms were associated with lower socio-moral maturity stages (SMR task) LIMITATIONS: Directional associations were not studied, and the sample included only girls.Conclusions: Findings may help to explain clinical heterogeneity in social cognitive functioning observed in individuals with depression. [ABSTRACT FROM AUTHOR]- Published
- 2022
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7. Emotional facial expression recognition and depression in adolescent girls: Associations with clinical features.
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Porter-Vignola, Elyse, Booij, Linda, Bossé-Chartier, Gabrielle, Garel, Patricia, and Herba, Catherine M.
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DEPRESSION in adolescence , *TEENAGE girls , *FACIAL expression , *SELF-expression , *SADNESS , *ANTIDEPRESSANTS , *FACIAL expression & emotions (Psychology) - Abstract
• Adolescents with depression were marginally faster than those in the comparison group to recognise sadness, although this trend disappeared once covarying for age and use of antidepressant medication. • Within the depression group, severity of depression symptoms and borderline personality features were associated with poorer emotional facial expression recognition (EFER) performance. • Discrepancies between group and within-group differences may explain some of the clinical heterogeneity observed in studies of EFER amongst adolescents with depression. • Studying clinical features in relation to EFER in adolescents with depression allows for a more nuanced understanding of social difficulties that may be experienced in depression. Studies have reported that emotional facial expression recognition (EFER) may be altered in individuals with depression. This study examined EFER in adolescent girls with and without depression and further examined associations between relevant clinical features of depression and EFER. Fifty adolescent girls aged 12 to 19 years old meeting criteria for depression or subthreshold levels of symptomatology and 55 adolescent girls with no psychiatric diagnosis completed EFER tasks. Reaction time and accuracy for recognising expressions at high and low intensities, and sensitivity in recognising happiness, sadness, anger and fear were assessed. Data were analysed using linear mixed models. Adolescents with depression were marginally faster than those in the comparison group to recognize sadness, although this trend disappeared once covarying for age and antidepressant use. Amongst adolescents with depression, clinical features were associated with poorer EFER performance. In contrast, anxiety symptoms were linked to better accuracy and heightened sensitivity towards happiness. A better understanding of EFER in adolescent girls with and without depression, and how clinical features might be associated with altered patterns of EFER could help to explain clinical heterogeneity observed in such studies of adolescents with depression. Knowledge of socio-cognitive alterations associated with depression will help to better develop and tailor interventions. [ABSTRACT FROM AUTHOR]
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- 2021
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8. Age‐specific associations between oestradiol, cortico‐amygdalar structural covariance, and verbal and spatial skills.
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Nguyen, Tuong‐Vi, Jones, Sherri Lee, Gower, Tricia, Lew, Jimin, Albaugh, Matthew D., Botteron, Kelly N., Hudziak, James J., Fonov, Vladimir S., Louis Collins, D., Campbell, Benjamin C., Booij, Linda, Herba, Catherine M., Monnier, Patricia, Ducharme, Simon, Waber, Deborah, and McCracken, James T.
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READING comprehension ,ESTRADIOL ,CINGULATE cortex ,AGE factors in memory ,ABILITY ,SPATIAL memory ,SHORT-term memory - Abstract
Oestradiol is known to play an important role in the developing human brain, although little is known about the entire network of potential regions that might be affected and how these effects may vary from childhood to early adulthood, which in turn can explain sexually differentiated behaviours. In the present study, we examined the relationships between oestradiol, cortico‐amygdalar structural covariance, and cognitive or behavioural measures typically showing sex differences (verbal/spatial skills, anxious‐depressed symptomatology) in 152 children and adolescents (aged 6‐22 years). Cortico‐amygdalar structural covariance shifted from positive to negative across the age range. Oestradiol was found to diminish the impact of age on cortico‐amygdalar covariance for the pre‐supplementary motor area/frontal eye field and retrosplenial cortex (across the age range), as well as for the posterior cingulate cortex (in older children). Moreover, the influence of oestradiol on age‐related cortico‐amygdalar networks was associated with higher word identification and spatial working memory (across the age range), as well as higher reading comprehension (in older children), although it did not impact anxious‐depressed symptoms. There were no significant sex effects on any of the above relationships. These findings confirm the importance of developmental timing on oestradiol‐related effects and hint at the non‐sexually dimorphic role of oestradiol‐related cortico‐amygdalar structural networks in aspects of cognition distinct from emotional processes. [ABSTRACT FROM AUTHOR]
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- 2019
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9. Sex‐specific contribution of DHEA‐cortisol ratio to prefrontal‐hippocampal structural development, cognitive abilities and personality traits.
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Farooqi, Nasr A. I., Scotti, Martina, Yu, Ally, Lew, Jimin, Monnier, Patricia, Botteron, Kelly N., Campbell, Benjamin C., Booij, Linda, Herba, Catherine M., Séguin, Jean R., Castellanos‐Ryan, Natalie, McCracken, James T, and Nguyen, Tuong‐Vi
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PERSONALITY ,PERSONALITY & intelligence ,HUMAN sexuality ,VERBAL memory ,CENTRAL nervous system ,YOUNG adults - Abstract
Although dehydroepiandrosterone (DHEA) may exert neuroprotective effects in the developing brain, prolonged or excessive elevations in cortisol may exert neurotoxic effects. The ratio between DHEA and cortisol (DC ratio) has been linked to internalising and externalising disorders, as well as cognitive performance, supporting the clinical relevance of this hormonal ratio during development. However, the brain mechanisms by which these effects may be mediated have not yet been identified. Furthermore, although there is evidence that the effects of cortisol in the central nervous system may be sexually dimorphic in humans, the opposite is true for DHEA, with human studies showing no sex‐specific associations in cortical thickness, cortico‐amygdalar or cortico‐hippocampal structural covariance. Therefore, it remains unclear whether sex moderates the developmental associations between DC ratio, brain structure, cognition and behaviour. In the present study, we examined the associations between DC ratio, structural covariance of the hippocampus with whole‐brain cortical thickness, and measures of personality, behaviour and cognition in a longitudinal sample of typically developing children, adolescents and young adults aged 6‐22 years (N = 225 participants [F = 128]; 355 scans [F = 208]), using mixed effects models that accounted for both within‐ and between‐subject variances. We found sex‐specific interactions between DC ratio and anterior cingulate cortex‐hippocampal structural covariance, with higher DC ratios being associated with a more negative covariance between these structures in girls, and a more positive covariance in boys. Furthermore, the negative prefrontal‐hippocampal structural covariance found in girls was associated with higher verbal memory and mathematical ability, whereas the positive covariance found in boys was associated with lower cooperativeness and reward dependence personality traits. These findings support the notion that the ratio between DHEA and cortisol levels may contribute, at least in part, to the development of sex differences in cognitive abilities, as well as risk for internalising/externalising disorders, via an alteration in prefrontal‐hippocampal structure during the transition from childhood to adulthood. [ABSTRACT FROM AUTHOR]
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- 2019
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10. Adversity in early adolescence promotes an enduring anxious phenotype and increases serotonergic innervation of the infralimbic medial prefrontal cortex.
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Tao, Cindy S., Dhamija, Prateek, Booij, Linda, and Menard, Janet L.
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SEROTONINERGIC mechanisms , *INNERVATION , *PHENOTYPES , *ADOLESCENT psychology , *IMMUNOHISTOCHEMISTRY , *HIPPOCAMPUS (Brain) - Abstract
Stress during early development produces lasting effects on psychopathological outcomes. We analysed the impact of prior intermittent, physical stress (IPS) during early adolescence (PD 22–33) on anxiety-like behaviour of female rats in adulthood. After behavioural testing, we used immunohistochemistry for the 5-HT transporter (SERT) to evaluate 5-HT innervation profiles in the medial prefrontal cortex (mPFC) and ventral hippocampus (VH). Administration of IPS (i.e., water immersion, elevated platform, foot shock) in early adolescence increased rats’ anxiety-like behaviour in the elevated plus-maze but had no effects in the shock-probe burying test. In the social interaction test, IPS decreased social interaction, and this effect was driven by selective decreases in the frequency of playfighting with no evident changes in contact and investigative behaviours. Selective stress-induced increases in the density of SERT- ir positive fibres were found in the infralimbic (IL) subregion of the mPFC but not in the cingulate or prelimbic (PL) subregions. IPS in early adolescence did not affect 5-HT innervation profiles in any sub-fields of the VH. Our findings confirm and extend on earlier evidence that stress during early adolescence promotes the emergence of an anxious phenotype and provide novel evidence that these effects are associated with increased 5-HT innervation of the IL mPFC. [ABSTRACT FROM AUTHOR]
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- 2017
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11. Is subthreshold depression in adolescence clinically relevant?
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Noyes, Blake K., Munoz, Douglas P., Khalid-Khan, Sarosh, Brietzke, Elisa, and Booij, Linda
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DEPRESSION in adolescence , *MENTAL depression , *MEDICAL care use , *BRAIN anatomy , *DISEASE progression , *SUICIDE risk factors , *THRESHOLD (Perception) , *DIAGNOSIS of mental depression , *SYSTEMATIC reviews , *LITERATURE reviews , *COMORBIDITY - Abstract
Background: Subthreshold depression is highly prevalent in adolescence, but compared to major depressive disorder, the clinical impact is under-researched. The aim of this review was to compare subthreshold depression and major depressive disorder in adolescents by reviewing available literature on epidemiology, risk factors, illness trajectories, brain anatomy and function, genetics, and treatment response.Methods: We conducted a scoping review of papers on subthreshold depression and major depressive disorder in adolescence published in English. Studies in adults were included when research in adolescence was not available.Results: We found that individuals with subthreshold depression were similar to individuals with major depressive disorder in several regards, including female/male ratio, onset, functional impairment, comorbidity, health care utilization, suicidal ideation, genetic predisposition, brain alterations, and treatment response. Further, subthreshold depression was about two times more common than major depressive disorder.Limitations: The definition of subthreshold depression is highly variable across studies. Adolescent-specific data are limited in the areas of neurobiology and treatment.Conclusions: The findings of the current review support the idea that subthreshold depression is of clinical importance and provide evidence for a spectrum, versus categorical model, for depressive symptomatology. Given the frequency of subthreshold depression escalating to major depressive disorder, a greater recognition and awareness of the significance of subthreshold depression in research, clinical practice and policy-making may facilitate the development and application of early prevention and intervention. [ABSTRACT FROM AUTHOR]- Published
- 2022
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12. Dehydroepiandrosterone impacts working memory by shaping cortico-hippocampal structural covariance during development.
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Nguyen, Tuong-Vi, Wu, Mia, Lew, Jimin, Albaugh, Matthew D, Botteron, Kelly N, Hudziak, James J, Fonov, Vladimir S, Collins, D. Louis, Campbell, Benjamin C, Booij, Linda, Herba, Catherine, Monnier, Patricia, Ducharme, Simon, and McCracken, James T
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DEHYDROEPIANDROSTERONE , *ADRENOCORTICAL hormones , *SHORT-term memory , *NEURAL development , *DEVELOPMENTAL neurobiology - Abstract
Existing studies suggest that dehydroepiandrosterone (DHEA) may be important for human brain development and cognition. For example, molecular studies have hinted at the critical role of DHEA in enhancing brain plasticity. Studies of human brain development also support the notion that DHEA is involved in preserving cortical plasticity. Further, some, though not all, studies show that DHEA administration may lead to improvements in working memory in adults. Yet these findings remain limited by an incomplete understanding of the specific neuroanatomical mechanisms through which DHEA may impact the CNS during development. Here we examined associations between DHEA, cortico-hippocampal structural covariance, and working memory (216 participants [female=123], age range 6–22 years old, mean age: 13.6 +/−3.6 years, each followed for a maximum of 3 visits over the course of 4 years). In addition to administering performance-based, spatial working memory tests to these children, we also collected ecological, parent ratings of working memory in everyday situations. We found that increasingly higher DHEA levels were associated with a shift toward positive insular-hippocampal and occipito-hippocampal structural covariance. In turn, DHEA-related insular-hippocampal covariance was associated with lower spatial working memory but higher overall working memory as measured by the ecological parent ratings. Taken together with previous research, these results support the hypothesis that DHEA may optimize cortical functions related to general attentional and working memory processes, but impair the development of bottom-up, hippocampal-to-cortical connections, resulting in impaired encoding of spatial cues. [ABSTRACT FROM AUTHOR]
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- 2017
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13. Fonctionnement émotionnel et social des adolescents dépressifs, de leur fratrie et d’un groupe témoin : étude transversale
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Bossé-Chartier, Gabrielle, Booij, Linda, Herba, Catherine, and Garel, Patricia
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Reconnaissance d'expression faciale ,Adolescent ,Depression ,Siblings ,Dépression ,Fratrie ,Cognition sociale ,MASC ,Facial recognition ,Social cognition ,Maladie affective ,Affective disorders ,Adolescence - Abstract
Contexte : la présence d’un biais cognitif négatif chez les individus qui souffrent de dépression majeure (DM) et ceux qui y sont à haut risque (e.g. enfants de mères qui souffrent de DM) est maintenant établie. Aucune étude portant sur la vulnérabilité cognitive (VC) des membres de la fratrie n’est rapportée. Objectifs : la présente étude a pour but de vérifier si la fratrie des adolescents qui souffrent de DM présentent une VC qui les prédisposent à la DM. Méthode : cette étude porte sur 49 adolescents (18 participants traités pour une DM, 16 membres de la fratrie et 15 participants témoin), âgés entre 12 et 20 ans. La VC de chaque participant est quantifiée via un questionnaire qui mesure la réactivité cognitive (RC), soit le LEIDS-R, et une tâche de reconnaissance des expressions faciale (REF). La cognition sociale des participants est mesurée par le MASC, un outil qui évalue la cognition sociale par médium vidéo et que notre équipe a traduit de l’allemand au français. Résultats : les résultats préliminaires de la présente étude indiquent qu’une différence de réactivité cognitive est présente entre les adolescents traités pour une DM et les participants du groupe témoin (p < 0,001). L’analyse préliminaire tend à indiquer qu’une différence est présente entre la fratrie et le groupe contrôle. Conclusion : plusieurs de nos résultats tendent en faveur de la présence d’une VC prédisposant à la DM chez la fratrie des adolescents souffrant de DM. Ces résultats préliminaires doivent être confirmés par des études longitudinales., Background: a negative cognitive bias is present among individuals who suffers from major depression. This bias is also reported among individuals at high risk of major depression (e.g. child of depressed mother). No study to date aimed to evaluate cognitive vulnerability of siblings of depressed individuals. Objectives: the present study aim to verify if siblings of depressed adolescents present a cognitive vulnerability that would predispose them to develop a major depression. Method: This study evaluates 49 adolescents (18 participants treated for depression, 16 siblings and 15 controls), aged between 12 and 20 years old. The cognitive vulnerability of every participant has been assessed using an auto-report questionnaire of symptoms (LEIDS-R) that evaluates cognitive reactivity and a task of facial recognition. Social cognition of participants is measured using the Movie for Assessment of Social Cognition (MASC) that we translated from german to french. Results: the preliminary analyses of this study concludes that a significant difference of cognitive reactivity is present between adolescents treated for depression and controls (p < 0.001). Conclusion: some of our results tend to confirm the presence of a cognitive vulnerability to depression among siblings of depressed adolescents. Those results are still preliminary and need to be confirmed by longitudinal studies., Réalisé sous la co-direction de Linda Booij, Catherine Herba et Patricia Garel
- Published
- 2014
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