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We conducted a clinical trial to analyze human serum containing carbamazepine by using the differential pulse voltammetry (DPV) method with a glassy carbon electrode, and compared it with the fluorescence polarization immunoassay (FPIA). Thirty patients, who visited our hospital to have their serum carbamazepine level checked, were enrolled. Ten mL of venous blood was collected from each patient and analyzed by DPV and FPIA methods. The correlation between the carbamazepine concentrations determined by DPV and FPIA was good, with an RSQ of 0.998. The similarity of the results indicates that these two methods can be used interchangeably. The DPV method using a glassy carbon electrode may be a potential alternative method to determine the carbamazepine level in human serum. Keywords: electrochemical method, differential pulse voltammetry, glassy carbon electrode, drug monitoring, immunoassay, carbamazepine, human serum DOI: 10.1134/S1061934814010110, Carbamazepine is a drug used for treating seizures. The monitoring of its serum concentration is very important in patients who take carbamazepine because side effects, such as dizziness, sleepiness, coma, [...]

Objectives: To determine the efficacy of a two week and a four week course of oral steroids in the conservative treatment of carpal tunnel syndrome. Methods: 109 patients with carpal [...]

Studies the long-term effectiveness of oral steroids given for 2 weeks compared with 4 weeks in patients with carpal tunnel syndrome (CTS). Prednisolone for 2 weeks versus 4 weeks for CTS at 12 months; Relative benefit reduction among patients.