Search

Introduction: In recent years, graph neural network has been extensively applied to drug discovery research. Although researchers have made significant progress in this field, there is less research on bibliometrics. The purpose of this study is to conduct a comprehensive bibliometric analysis of graph neural network applications in drug discovery in order to identify current research hotspots and trends, as well as serve as a reference for future research. Methods: Publications from 2017 to 2023 about the application of graph neural network in drug discovery were collected from the Web of Science Core Collection. Bibliometrix, VOSviewer, and Citespace were mainly used for bibliometric studies. Results and Discussion: In this paper, a total of 652 papers from 48 countries/regions were included. Research interest in this field is continuously increasing. China and the United States have a significant advantage in terms of funding, the number of publications, and collaborations with other institutions and countries. Although some cooperation networks have been formed in this field, extensive worldwide cooperation still needs to be strengthened. The results of the keyword analysis clarified that graph neural network has primarily been applied to drugtarget interaction, drug repurposing, and drug-drug interaction, while graph convolutional neural network and its related optimization methods are currently the core algorithms in this field. Data availability and ethical supervision, balancing computing resources, and developing novel graph neural network models with better interpretability are the key technical issues currently faced. This paper analyzes the current state, hot spots, and trends of graph neural network applications in drug discovery through bibliometric approaches, as well as the current issues and challenges in this field. These findings provide researchers with valuable insights on the current status and future directions of this field. [ABSTRACT FROM AUTHOR]

This paper presents a bibliometric analysis of battery state estimation in electric vehicles. In this paper, a quick study is performed on the top global research contributors, funding agencies, and affiliate universities or institutes performing research on this topic while also finding the top keyword searches and top authors based on the most citations in the field of electric vehicles. Trend analysis is done by using the SCOPUS and Web of Science (WOS) databases (DB) from the period of 2000 to 2021. Battery state estimation plays a major role in the battery present state based on past experience. Battery available charge and health knowledge is a must for range estimation and helps us acknowledge if a battery is in useful condition or needs maintenance or replacement. A total of 136 documents in SCOPUS and 1311 documents in Web of Science were analyzed. Through this bibliometric analysis, we learn the top authors, country, publication journal, citation, funding agency, leading documents, research gap, and future trends in this research direction. The author Xiong Rui has the most publications, and he is working at the Beijing Institute of Technology, China. The most common institution is the Beijing Institute of Technology, and China is the most highly contributing country in this research. Most of the publications are conference types in SCOPUS DB and article types in WOS DB. The National Natural Science Foundation of China provides the most funding. The journal Energies has the most publications related to this field. The most cited works are by the authors M.A. Hannan and L.G. Lu in SCOPUS and WOS DB, respectively. A statistical analysis of the top ten countries' productivity results is also discussed. [ABSTRACT FROM AUTHOR]

The superiority of BWM over other weighting methods for obtaining the weight values of the attributes is that it achieves high-confidence results with a reasonable number of pairwise comparisons. Although the best-worst method (BWM) is a well-known multi-criteria decision-making (MCDM) method that has been successfully utilized in almost all scientific areas to solve challenging real-life problems, no research has comprehensively examined the state-of-the-art in this regard. The present study depicts a detailed overview of publications concerned with BWM during the period 2015–2022. Based on the information obtained from the Scopus database, this work presents a big picture of current research on BWM. In other words, this paper analyzes the existing literature about BWM and identifies thematic contexts, application areas, emerging trends, and remaining research gaps to shed light on future research agendas aligning with those gaps. Further, the most recent BWM research is analyzed in the top ten scientific areas, from engineering to materials science. “Engineering”, “computer science”, and “business, management, and accounting” are the hottest fields of BWM research. China is the most active country regarding “engineering” and “computer science”, whereas India is the leader in “business, management, and accounting”. The study also reveals that there are still many research gaps in BWM research. The big picture taken in this study will not only showcase the current situation of BWM research but will also positively impact the direction and quality of new research. [ABSTRACT FROM AUTHOR]

Background: Electroacupuncture has been used as a treatment; however, a visual bibliometric analysis has not yet been performed in this field. In this study, we aimed to suggest future research topics and directions related to the field by examining the last 20years of research trends and hotspots of electroacupuncture in stroke. Methods: We searched the Web of Science database on electroacupuncture as a treatment for stroke published from 2003 to 2022. We analyzed the papers by annual publication, research fields, nations, affiliations, authors, journals, and keywords. VOSviewer software was used to visualize the bibliometric analysis and results. A total of 440 papers were included in the analysis. Results: The number of publications has gradually increased every year, and neuroscience has become the most actively studied field. Neural Regeneration Research journal and China had the most publications. Fujian University of Traditional Chinese Medicine, as an affiliated institute, published the most articles. Chen Lidian and Tao Jing presented the largest number of papers, making them the leading contributors in this field. Four clusters were created by analyzing keywords, such as "neuroprotection," "clinical rehabilitation," "neuroplasticity," and "pretreatment-induced tolerance". Conclusion: This study is the first to analyze the research trends in electroacupuncture as a treatment for stroke using the VOSviewer. It shows the current state of research in the field by visualizing research trends and hotspots. This will help offer reference data for future studies. [ABSTRACT FROM AUTHOR]

5G (5th Generation) and the related technologies implementation are expected in 2020. The 5G is considered to be a breakthrough of IoT devices in terms of enhanced bandwidth, efficiency, reliability and energy consumption. This study focuses on quantitative and qualitative progression of research in the field of 5G. It also provides the publishing trend, most productive and cited countries, organizations, and authors on 5G. In addition, it identifies the most frequently used keywords, authorship pattern and preferred journals. The research is based on 5G related research from Scopus database, which includes all relevant keywords of the field limiting it to conference papers, articles, book chapters, editorial and books. The outcome of the study revealed that 5G related research is on the rise worldwide. The number of yearly published articles has increased from one to 2222 during the period between 2003 and 2020. China, United States and United-Kingdom are most productive countries. Beijing University of Posts and Telecommunications have taken lead in publishing 5G research. Furthermore, it is noteworthy that 19 out of these 20 most productive organizations in the world, seven belong to China. Majority of top 10 preferred journals are Q1 and published by IEEE (Institute of Electrical and Electronics Engineers). The most popular authorship pattern is three-authors. In subcategories of wireless networks, 5G communication gets a lot of attention. [ABSTRACT FROM AUTHOR]

Landscape engineering plays a crucial role in urban construction and the development of ecological civilization in China. It actively designs and modifies natural elements, such as water and mountains, acting as the primary living infrastructure. This field continually receives great recognition and praise. Recent academic research has prioritized the use of extended reality (XR) technology to create a real-time interactive visual environment to tackle the issues presented by the dynamic nature of landscape engineering. This paper utilizes the PRISMA method to filter out 68 research documents related to XR in landscape engineering construction and management for bibliometric analysis. A comprehensive review is conducted on the precise and efficient utilization of XR to solve various issues in the field of landscape engineering. Using Cite Space 6.2.R6 (a visual bibliometric software) to visualize knowledge structures and research topics, the analysis includes temporal and spatial examination, application scenario analysis, and technological hierarchy analysis. The paper summarizes the current challenges that XR still faces in the landscape engineering field and envisions extensible application scenarios for XR, providing a reference roadmap for the implementation of XR in landscape engineering. [ABSTRACT FROM AUTHOR]

This study offers a comprehensive insight into the realms of economic fraud and risk management, underscoring the necessity of adaptability to evolving technologies and shifts in financial market dynamics. Through the application of bibliometric methodologies, this study meticulously maps the relevant literature, delineating influential works, notable authors, collaborative networks, and emerging trends. It reviews key research contributions within the field, alongside reputable journals and institutions engaged in academic research. The examination highlights the logical, conceptual, and social interconnections that define the landscape of economic fraud and associated risks, elucidating how these findings inform the understanding, mitigating, and combating of the risk of fraud. Our bibliometric analysis methodology is grounded in the utilization of the Scopus database, employing rigorous filtering and extraction processes to obtain a substantial corpus of pertinent articles. Through a fusion of performance analysis and science mapping, our investigation elucidates central themes and visually represents the interrelationships between studies. Our research outcomes underscore the frequency of paper publications across diverse regions, with particular emphasis on the predominant scientific output from the US and China. Additionally, trends in academic citations are identified, indicative of the significant impact of papers on academic research and the formulation of public policies. By means of bibliometric analysis, this study not only consolidates existing knowledge but also catalyzes the exploration of future research trajectories, emphasizing the imperative of addressing these issues with heightened scientific rigor. [ABSTRACT FROM AUTHOR]

Scholars from Mainland China have published 8541 papers in 79 Operations Research and Management Science (OR/MS) journals available on the ISI Web of Science (WOS). Data from 2001 to 2013 constitute the basis of the bibliometric method used in this paper for statistical analysis of status of OR/MS research in Mainland China, from the perspectives of number of papers, quality of papers, most productive institutions, co-author analysis, citations analysis and research topic analysis, etc. The results show that although the number of OR/MS papers by Mainland China scholars grew exponentially during this period, the quality of papers needs to be further improved. Besides, the competition among the institutions in Mainland China is very fierce. Furthermore, the co-author analysis shows that the depth of cooperation has increased steadily and yet the breadth of cooperation has much room for development. Moreover, from the perspective of citations, only a small number of papers by Mainland China scholars have influenced the international OR/MS field. In addition, analysis of research topics shows that Mainland China scholars have been studying the OR/MS problems from a variety of perspectives. Additionally, we also visualize the relationship of the keywords to describe the status of development of the OR/MS discipline in Mainland China, and conclude that the connection nodes will have greater potential in the future. [ABSTRACT FROM AUTHOR]

Objective: This study points to probing the inclination and mapping knowledge domain of acupuncture for Parkinson's disease through bibliometrics. Methods: A search was conducted on 1 February 2024 using the Web of Science to identify papers published on acupuncture for Parkinson's disease. The analysis included scientific research, countries, organizations, authors/cited authors, keywords, journals, and cited references. Bibliometric data were analyzed using VOSviewer software, CiteSpace, GraphPad Prism, and Scimago Graphica. The studies on acupuncture for Parkinson's disease were visualized as a network map according to the publication year. Results: The cumulative publication trend on acupuncture for Parkinson's disease is increasing year by year. China is the leading contributor in this field. International collaboration is predominantly concentrated in Europe, while institutional collaboration is chiefly limited to Chinese universities specializing in traditional Chinese medicine. Park HJ is the most prolific author, with "Movement Disorders" being the journal with the most publications. "Brain Research" is identified as a key journal, reflecting a focus on neuroscience. Kim SN is the most cited author, while Eisenberg DM is a prominent author in this field. Research topics such as mouse models, systematic reviews, and non-motor symptoms are frequently explored, with messenger RNA of substantia nigra emerging as a notable keyword in this field. Choi YG's 2009 paper, published in the Neuroscience Letters journal, is a critical reference in this field. Key papers include Eisenberg DM's 1998 study on randomized trials of acupuncture for non-motor symptoms of PD, as well as research focusing on the neuroinflammatory regulatory mechanisms of acupuncture for PD. Conclusion: The bibliometric analysis offers an exhaustive generality of the advancement and worldwide trends in acupuncture treatments for Parkinson's disease, shedding light on potential avenues for prospective research. [ABSTRACT FROM AUTHOR]

Introduction: Head and neck cancer is one of the most common tumors worldwide. However, drug resistance in its treatment has become a major factor limiting the efficacy. This study aims to comprehensively understand the current status of research in this field. Methods: The study analyzes papers related to therapeutic resistance in head and neck cancer published between 2000 and 2023 in the Web of Science Core Collection To achieve the research objectives, we searched the WoSCC for research and review papers on therapeutic resistance in head and neck cancer from 2000 to 2023, screened the English literature, and analyzed the research hotspots, academic collaborations, and trends in detail using tools such as Citespace, SCImago Graphica, and VOS viewer. Results: This study summarizes 787 head and neck cancer treatment resistance publications from WoSCC. The analysis showed that China and the United States are the major contributors in this field, and Grandis Jennifer R and Yang Jai-Sing are the key scholars. Keyword analysis showed that "cisplatin resistance" is a continuing focus of attention, while "Metastasis" and "Ferroptosis" may be emerging research hotspots. Literature clustering analysis pointed out that "Ferroptosis", "Immunotherapy" and "ERK signaling" were the recent hotspots that received extensive attention and citations. Finally, we discuss the current status and challenges in drug-resistant therapies for head and neck cancer. Conclusion: This study is the first comprehensive bibliometric analysis of drug resistance in head and neck cancer. Reveals current trends and helps researchers grasp cutting-edge hotspots in the field. [ABSTRACT FROM AUTHOR]

Over the last decade, research on evolving computational thinking (CT) has garnered heightened attention. Assessing the publication tendencies and nucleus contents of investigations on progressing CT to direct future research initiatives, develop policies, and integrate them into instructional materials is timely and exceedingly essential in education. Therefore, this research reviewed publications on progressing CT to identify research trends and core contents published in the Scopus database from 2008 to May 2022. For this reason, this study applied bibliometric and content analysis to 132 selected publications. After examining bibliometrics, the findings indicate a steady increase in publications related to game-based learning (GBL) and CT, reaching a peak in 2021, with the United States emerging as the most prolific contributor in terms of authors, institutions, and countries). The leading country in citations is primarily China. The document that received the most citations is Hsu's 2018 paper on "Computers and Education". Analysis of keywords and themes reveals core content tendencies, emphasizing teaching methods and attitudes aimed at improving CT via GBL. These results offer valuable insights for researchers and educators to inform their future work. However, future studies may benefit from including other databases such as Web of Science (WoS) and PubMed, employing alternative bibliometric software like VOSviewer or CiteSpace, as well as collecting data from June 2022. [ABSTRACT FROM AUTHOR]

As High Speed Rail (HSR) has proliferated globally, so has a related research field dedicated to exploring and addressing its unique issues. Yet, studies to understand and classify the HSR research domain are limited. This paper addresses the gap, using bibliometric analysis to identify future research areas and 20 candidate topics for literature review based on keyword analysis through VOSviewer. Article and review papers related to HSR published in the last 20 years (2003-2022) were retrieved from Scopus, and then analyzed to determine the split in knowledge between languages, the collaboration between countries and institutions, highly productive and cited journals, and research topics which have and have not been reviewed. Approximately 30% of the search results were published exclusively in Chinese, highlighting the importance of extending the evaluation to cover both languages. This is a novel aspect of the work, which has enabled the recognition of potential knowledge gaps. It is recommended that future reviews incorporate works in both languages, possibly through international collaboration. Institutions in China and other countries that are strong collaborators have been identified, as well as relevant, highly cited journals. [ABSTRACT FROM AUTHOR]

The land use, land-use change and forestry (LULUCF) sector, as a source and a sink of greenhouse gas (GHG) emissions, is critical for achieving carbon neutrality. Many academic journals have published papers on land use carbon emission or sink (LUCES), but LUCES reviews are relatively rare, which poses great challenges in accurately understanding the research progress and future prospects. This work analyzes the research characteristics, hotspots and future perspectives of LUCES research by using a bibliometric analysis (such as DDA, VOSviewer, CiteSpace software) and a review based on the data (6115 scientific papers) during 1991–2023 from the Web of Science (WoS) platform. We found that (1) over the past 33 years, it first presented a steady growth, then fluctuating growth, and finally a rapid growth trend in the yearly number of publications in LUCES research. The USA (17.31%), China (14.96%), and the UK (7.37%) occupy a dominant position in this research field. (2) The related LUCES research is interdisciplinary, which mainly cover science and technology, meteorology and atmospheric sciences, geology, and environmental sciences and ecology disciplines. (3) The research hotspot analysis on LUCES shows that these articles mostly covered the follow three aspects: ecosystem services, climate change, and carbon neutrality. (4) A review of the past LUCES literature suggests that it is mainly focused on exploring the forefront issues in terms of the definition and boundaries, evaluation method and influencing factors, etc. This work suggests that further research could explore the main scientific problems on quantification of land-based carbon neutrality, quantitative analysis of the impact mechanisms, as well as interdisciplinary research and collaborative governance needed for carbon neutrality. [ABSTRACT FROM AUTHOR]

The precise and visual analysis of solid waste recycling in concrete construction engineering is critical for the development of ecological civilization and for the secure supply of resources. This research makes a bibliometric analysis of the solid waste application in concrete construction engineering from 2000 to 2021 based on the Web of Science. The global bibliometric status, current research focus and future directions were used to indicate the global development of solid waste recycling in concrete construction engineering. The most reused solid wastes and most solid waste productive regions were concluded with this bibliometric analysis. China is far ahead of other countries in solid waste recycling in all aspects and heavy metal is one of the most prominent solid waste themes in China. By analyzing the most studied solid waste, fly ash appears to be the most popular and is widely used; half of the top ten-cited papers are correlated with it. [ABSTRACT FROM AUTHOR]

Permafrost is a significant part of the cryosphere, which has gained increasing attention from scientists, policy-makers, and the general public due to global warming, environmental degradation, water shortages, and intense human activities. Although many permafrost research review articles have been published, these studies were predominantly limited to either one subject or one field, while systematic studies about permafrost based on bibliometric analysis methods remain limited. We aim to fill this gap by conducting a bibliometric analysis of 13,697 articles in the field of permafrost research from 1942 to 2021, collected from the Web of Science core collection database. The results indicate that permafrost research is a typically multi-author, multi-country, and multi-institution cooperative field, involved in many research fields. The cumulative number of publications has presented an exponential increase over the past 80 years, with an average annual growth rate of 10.40%. Since 2000, China has seen a rapid growth in the number of publications per year, surpassing the USA in 2016 and leading in the years since then. In addition, the authors from China have great contributions in publications, and there is good room for permafrost development in the future according to the authors' M-index ranking. After the analysis of authors' keywords, we found that, compared to the conventional methods, machine learning and interferometric synthetic aperture radar (InSAR) are new technological approaches introduced in recent years, and the Qinghai–Tibet Plateau has become a popular study area. The results presented here can help related researchers, scholars, and students in the field to better understand the past developments, current status, and future trends of permafrost research. Furthermore, this paper presents and expands the general process of the bibliometric method used in permafrost studies, which can provide researchers with new inspirations and improve discipline research approach. [ABSTRACT FROM AUTHOR]

This article explores the concept of "immigrant consumption behavior (ICB)" in the context of its holistic surroundings. The study investigated the current dynamics and scientometrics of the research field regarding immigrant consumption behaviors. Using an integrative approach employing bibliometric and content analysis, it scrutinized a collection of 224 studies from the Web of Science and Scopus databases to detect the field evolution, disciplinary distribution thematic map, and emerging trends in the ICB literature, as well as to forecast research directions. The results showed that ICB is a multi- and inter-disciplinary research area that experienced three phases of growth between 1989 and 2023: initiation (1989–2006), development (2007–2012), and consolidation (2013–now). The thematic analysis revealed five current trends, i.e., (1) the immigrant consumption behavior domain, (2) the demographic sub-groups of immigrants and related consuming products, (3) country-, region-, and cultural-focused studies, (4) the effects of culture and the acculturation process, and (5) the impact of urbanization. Each theme contains a number of sub-themes. Based on the current thematic evolution and keyword burst analysis, this paper suggests a number of critical research directions, comprising (1) observatory studies including remittances, China, ethnic minorities, lifestyle, inequality, urbanization, and food consumption; (2) context-based studies focused on socioeconomic, cultural, legal, and environmental factors; (3) studies based on compensatory and compromissory consumption behavior; (4) studies focused on sustainable and green consumption behaviors; and (5) studies regarding the behavior of specific demographic co-ethnic communities. The results have great implications for developing interventions and programs that can support immigrant populations in making appropriate consumption patterns and adapting to new cultural environments. The paper pushes forward the ICB investigation from individual empirical studies to synthesis-based research, which (1) provides an ample overview of the ICB literature, (2) identifies research priorities, emerging trends, and gaps, (3) proposes new research avenues for investigation, and (4) outlines expected contributions. The research contributes to a variety of disciplines through the provision of new knowledge, since ICB studies are multidisciplinary in nature. It also has numerous implications for policymakers and practitioners. [ABSTRACT FROM AUTHOR]

Objective: This research aims to explore the trends and knowledge domain of acupuncture for cerebral infarction through bibliometrics. Methods: Publications related to acupuncture for cerebral infarction were retrieved from the Web of Science core collection database from 1993 to December 31, 2023. A domain knowledge graph was then constructed using VOSviewer, CiteSpace, GraphPad Prism, and Scimago Graphica. Results: The cumulative publication trend shows a steady increase over the years, with China being the most productive country. Notably, Europe exhibits significant close collaboration. Institutional cooperation is primarily observed among Chinese universities specializing in traditional Chinese medicine. Tao Jing is the most prolific author, with his highest number of publications is in "Stroke" journal, and Acupuncture Electro Therapeutics Research is the significantjournal. Zhang SH is the most cited author, and Si QM is a prominent author in this field. Rehabilitation treatment after cerebral infarction emerges as a prevalent research focus, with nerve regeneration being a keyword. Long EZ's 1989 paper, published in the journal Stroke, holds significant importance. The prominent papers are Donnan et al. and Wu et al., which covers the following topics: "population-based study," "Baihui Acupoint," "memory deficits," "neurotrophic factor," and "randomized trial." Conclusion: This bibliometric analysis of acupuncture for cerebral infarction offers insights into the Web of Science database, delineates a knowledge map of countries, authors, institutions, cited authors, keywords, cited references in the field of acupuncture for cerebral infarction, which has a momentous guiding significance for quickly and accurately positioning the key information in the field. [ABSTRACT FROM AUTHOR]

Background: Spinal cord injury (SCI) is a severe central nervous trauma that can cause serious consequences. Cell death is emerging as a common pathogenesis after SCI. In the last two decades, numerous studies have been published in the field of cell death after SCI. However, it is still rare to find relevant bibliometric analyses. This bibliometric study aims to visually represent global research trends in the field of cell death after SCI. Methods: Bibliometric data were sourced from the Web of Science Core Collection (WoSCC) database. VOSviewer, CiteSpace, and R software ("bibliometrix" package) were used to analyze and visualize bibliometric data. Annual scientific production, countries/regions, institutions, authors, journals, highly cited papers, keywords, and literature co-citation were evaluated to determine research performance. Results: An analysis of 5,078 publications extracted from the WoSCC database revealed a fluctuating yet persistent growth in the field of cell death after SCI over the past 23 years. China and the United States, contributing 69% of the total publications, were the main driving force in this field. The Wenzhou Medical University from China contributed to the most papers. In terms of authors, Salvatore Cuzzocrea from the University of Messina had the highest number of publications. The "Journal of Neurotrauma" was the top journal in terms of the number of publications, however, the "Journal of Neuroscience" was the top journal in terms of the number of citations. The theme of the highly cited articles mainly focused on the mechanism of cell death after SCI. The keyword and literature co-citation analysis mainly focused on the mode of cell death, mechanism research of cell death, and functional recovery after SCI. Conclusion: This study analyzes the research hotspots, frontiers, and development trends in the field of cell death after SCI, which is important for future studies. [ABSTRACT FROM AUTHOR]

Environmental regulation's impact on the labor market is a very important topic. However, there is a lack of systematic literature review detailing current research in this field. This paper attempts to make up for this gap by first establishing the theoretical model of the impact of environmental regulation on the labor market, then examines and discusses the impact mechanisms in combination with the existing literature. Last, this paper establishes a visual evaluation of the current literature in this field through bibliometric analysis. The results are as follows: (1) Econometric methods have become the mainstream in this field. (2) Environmental regulations mainly affect the labor market through the substitution effect and the output effect, which may act alone or in combination. Due to the relatively imperfect environmental policy-making and the labor market in developing countries, the negative impact of substitution effect and output effect is more profound. (3) The USA is an important contributor in this field, with the largest number of publications, followed by China. However, the average citation number of publications in China is 0.4 to that of US studies, indicating that the quality and influence of China's publications can be improved. (4) Among the academic cooperation in this field, Chinese scholars and American scholars have the closest cooperation. Scholars from developing countries, such as South America and Africa, rarely participate in international cooperation, with China being an exception. (5) The impact of environmental regulation on workers' wages and employment is the most popular topic in this field. (6) China and other developing countries will become research hot spots in the near future. This paper provides a summary of research methods in different areas of this field and identifies directions for future research. [ABSTRACT FROM AUTHOR]

Introduction: Brain metastasis is the terminal event of breast cancer with poor prognoses. Therefore, this article aimed to provide an updated summary on the development, hotspots, and research trends of brain metastasis from breast cancer based on bibliometric analysis. Method: Publications on breast cancer with brain metastasis retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, and other online bibliometric analysis platforms were used to analyze and visualize the result. Result: In totality, 693 researchers from 3,623 institutions across 74 counties and regions published a total of 2,790 papers in 607 journals. There was a noticeable increase in publications in 2006. The United States was the dominant country with the most publications followed by China. University Texas MD Anderson Cancer Centerwas the most productive institution, while Dana Farber Cancer Institution was the most cited. Journal of Neuro-Oncology published the most papers, while Journal of Clinical Oncology ranked first based on cocited analysis. Nancy U. Lin was the most productive and cited author with high influence. There was a focus on basic research, clinical trials, local therapy, treatment optimization, and epidemiological studies regarding brain metastases from breast cancer. References focused on pathogenesis, prevention, treatment, and prognosis were cited most frequently, among which the clinical trial of novel treatment attracted most attention from researchers. Reference citation burst detection suggested that new therapies such as the novel tyrosine kinase inhibitor and antibody-drug conjugate may lead the research trends in the future. Conclusion: High-income countries contributed more to the field of breast cancer with brain metastasis, while developing countries like China developed quickly. Furthermore, the success of novel therapies in recent years may lead to the new era of treatment of breast cancer with brain metastasis in the future. [ABSTRACT FROM AUTHOR]

This paper consists of a bibliometric study that covers the topic of 3D object detection from 2022 until the present day. It employs various analysis approaches that shed light on the leading authors, affiliations, and countries within this research domain alongside the main themes of interest related to it. The findings revealed that China is the leading country in this domain given the fact that it is responsible for most of the scientific literature as well as being a host for the most productive universities and authors in terms of the number of publications. China is also responsible for initiating a significant number of collaborations with various nations around the world. The most basic theme related to this field is deep learning, along with autonomous driving, point cloud, robotics, and LiDAR. The work also includes an in-depth review that underlines some of the latest frameworks that took on various challenges regarding this topic, the improvement of object detection from point clouds, and training end-to-end fusion methods using both camera and LiDAR sensors, to name a few. [ABSTRACT FROM AUTHOR]

Background: Papillary thyroid cancer (PTC) is the most common endocrine malignancy worldwide. The treatment of PTC has attracted extensive attention and discussion from the public and scholars. However, no article has systematically assessed the related literature. Therefore, we conducted a bibliometric and knowledge map analysis to reveal the dynamic scientific developments in the PTC therapy field. Methods: We retrieved publications related to PTC therapy from the Web of Scientific Core Collection (WoSCC) on May 1, 2023. The bibliometric package in R software, VOSviewer and CiteSpace software were used to analyze countries/ regions, institutions, journals, authors, references, and keywords. Then, we systematized and summarized the research landscape, global trends and hot topics of research. Results: This bibliometric analysis spanned from 2012 to 2022 and involved 18,501 authors affiliated with 3,426 institutions across 87 countries/regions, resulting in the publication of 3,954 papers in 860 academic journals. Notably, the number of publications and citations related to PTC therapy research has exhibited a steady increase over the past decade. China and the United States have emerged as leading contributors in terms of publication count, with the United States also being the most cited country. Furthermore, among the top 10 institutions with the highest number of published papers, half were located in China. Among the journals, Thyroid is ranked first in terms of total publications and citations. The most productive individual author was Miyauchi Akira. While previous research primarily focused on surgery and radioactive iodine therapy, the increasing emphasis on health awareness and advancements in medical technology have led to the emergence of active surveillance, thermal ablation, and genomic analysis as prominent areas of research. Conclusion: In conclusion, this comprehensive and quantitative bibliometric analysis elucidates the research trends and hotspots within PTC therapy, drawing rom a substantial body of publications. This study provides valuable insights into the historical and current landscape of PTC therapy research while also offering guidance for future research directions. This study serves as a valuable resource for researchers and practitioners seeking new avenues of exploration in the field. [ABSTRACT FROM AUTHOR]

Adequate blood supply, a prerequisite for flap survival after grafting, makes angiogenesis of the flap the biggest problem to be solved. Researches have been conducted around vascularisation in correlation with flap grafting. However, bibliometric analyses systematically examining this research field are lacking. As such, we herein sought to conduct comprehensive comparative analyses of the contributions of different researchers, institutions, and countries to this research space in an effort to identify trends and hotspots in angiogenesis and vascularisation in the context of flap grafting. Publications pertaining to angiogenesis and vascularisation in the context of flap grafting were retrieved from the Web of Science Core Collection. References were then analysed and plotted using Microsoft Excel 2019, VOSviewer, and CiteSpace V. In total, 2234 papers that were cited 40 048 times (17.63 citations/paper) were included in this analysis. The greatest number of studies were from the United States, with these studies exhibiting both the highest number of citations (13 577) and the greatest overall H‐index (60). For The institutions that published the greatest number of studies were WENZHOU MEDICAL UNIVERSITY (681), while UNIVERSITY OF ERLANGEN NUREMBERG has the highest number of citations (1458), and SHANGHAI JIAO TONG UNIVERSITY holds the greatest overall H‐index (20). The greatest number of studies in this research space were published by Gao WY, while Horch RE was the most commonly cited researcher in the field. The VOS viewer software clustered relevant keywords into three clusters, with clusters 1, 2, 3, and 4 corresponding to studies in which the keywords 'anatomy', 'survival', 'transplantation', 'therapy' most frequently appeared. The most promising research hotspot‐related terms in this field included 'autophagy', 'oxidative stress', 'ischemia/reperfusion injury', which exhibited a most recent average appearing year (AAY) of 2017 and after. Generally speaking, the results of this analysis indicate that the number of articles exploring angiogenesis and flap‐related research has risen steadily, with the United States and China being the two countries publishing the greatest proportion of studies in this field. The overall focus of these studies has shifted away from 'infratest and tissue engineering' towards 'mechanisms'. In the future, particular attention should be paid to emerging research hotspots, which include 'ischemia/reperfusion injury' and treatments for promoting vascularization, such as 'platelet‐rich plasma'. In light of these findings, funding agencies should continue increasing their investment in the exploration of the concrete mechanisms and interventional therapeutic relevance of angiogenesis during flap transplantation. [ABSTRACT FROM AUTHOR]

Nitrogen (N), an indispensable mineral nutrient element for plant growth and development, is a major limiting source of productivity in many terrestrial ecosystems. Soil organic nitrogen (SON) is a crucial form of nitrogen (N) in the N cycle within terrestrial ecosystems, acting as either a "source" or a "sink" for environmental N release. In order to illustrate the research trends, evolution process and hotspots of SON, a bibliometric analysis was used to analyze 906 documents based on the ISI (Institute of Scientific Information) Web of Science (WoS) database. The results indicated that (1) the number of published papers on SON research showed a wavy growth from 2000 to 2022 and the research has entered a mature development period; China has been increasing its number of publications and has long been in the lead; (2) the most productive institutions and authors in this subject area are in the USA and China, with the Chinese Academy of Sciences being the key institution performing such research; (3) in the sample, Soil Biology and Biochemistry, Science of the Total Environment, and Biogeochemistry are the leading international journals that have played a key role in the evolution of the field and have laid a solid foundation for future research; (4) the characteristics and maintenance of SON in farmland and SON migration in small watersheds under forest conversion have become research hotspots. Through the in-depth analysis of SON research, this paper provides a better understanding of the development trends of SON over the past 20 years, which can also provide reference for future research. [ABSTRACT FROM AUTHOR]

Platelet‐rich plasma (PRP) has attracted attention because of its potential to accelerate the wound healing process. However, resources for evaluating research trends in the treatment of wounds with PRP were limited. In this study, we aimed to make a bibliometric analysis of the literature related to PRP in the treatment of wounds and explore the research status, hotspots and frontiers in this field in recent 20 years. Studies about PRP treatment for wounds from 2002 to 2021 were retrieved from the Science Citation Index Expanded (SCI‐E) of Web of Science (WOS) database. Visualisation softwares such as VOSviewer and SCImago Graphica, and CiteSpace were used to analyse the research trends and features. A total of 1748 studies were identified in the SCI‐Expanded from 2002 to 2021. The number of publications on PRP in the treatment of wounds has shown an increasing trend, from 6 (in 2002) to 228 (in 2021). The papers published in the United States have led in times cited (14637) and H‐index (63). Though Italy was slightly lower than China in the number of publications, the H‐index and average cited (47, 28.45) were higher than that of China (38, 27.01). The strongest keyword was "fibrin" (strength = 13.07), and the longest burst duration keyword was "thrombin" (began in 2002 and ended in 2014). The largest 10 co‐citation clusters are as follows: endothelial cell proliferation (#0), regenerative medicine‐associated treatment (#1), diabetic wound healing (#2), autologous derived (#3), platelet‐rich fibrin (#4), tissue engineering (#5), regenerative potential (#6), clinical randomised trial (#7), histologic observation (#8), and wound bacteria (#9). The United States has made the most outstanding contribution in this field. Chinese researchers need to enhance the quality of publications further. Wound Repair Regen. is the most noteworthy journal. The mechanism of growth factors of PRP, combination therapy, preparation of PRP, and related clinical trials may be topics that need attention. [ABSTRACT FROM AUTHOR]

Background: While acupuncture treatment has gained extensive usage in addressing headaches, there remains a notable gap in the literature analysis for this field. Therefore, this study aims to conduct a literature review using Citespace, VOSviewer, and Bibliometrix, aiming to examine the current status, strengths, and potential future directions in the utilization of acupuncture for headache treatment. Methods: Relevant literature on acupuncture treatment for headaches between 2003 and 2023 was retrieved from the Web of Science (WoS) core database. Utilizing CiteSpace 6.1.R6, VOSviewer 1.6.18, and Bibliometrix 4.1.4, we conducted bibliometric analyses across various categories, including countries/regions, institutions, authors, journals, references, and keywords. Results: A total of 808 research reports were included. China and the United States have significantly contributed to this field. Chengdu University of Chinese Medicine holds the record for the highest number of published papers. Liu Lu has the highest publication output, while Linde K has the highest citation rate. MEDICINE leads in publication frequency, while CEPHALALGIA holds the highest citation rate. The Long-term Effect of Acupuncture for Migraine Prophylaxis a Randomized Clinical Trial is the most cited reference. Migraine was the most researched type. Filiform needle acupuncture was the most widely used stimulation method. The safety and efficacy of acupuncture have received significant attention. Modern mechanism research shows that depression, brain functional connectivity, and neuroimaging technology have become research hotspots in the acupuncture treatment of headaches. Conclusion: Acupuncture treatment for headaches has established a stable trend with a promising developmental trajectory. Research in this field mainly focuses on different acupuncture prevention and treatment for various types of headaches, the safety and efficacy of acupuncture, etc. Research on the mechanism of action mainly focuses on interpreting bidirectional and holistic regulation between pain and emotion by acupuncture and the regulation of brain function connection and neuroimaging technology by acupuncture. Future research should expand on the advantages and indications of acupuncture treatment for different headaches and their modern mechanisms. [ABSTRACT FROM AUTHOR]

Freshwater aquaculture plays an important role in the global aquaculture industry. The success of freshwater aquaculture relies on the integration of bio-ecological remediation technologies to ensure its sustainable development. This paper systematically reviews the global literatures on bio-ecological remediation of freshwater aquaculture environments from 1990 to 2021, and discusses in detail the research progress and status quo in this field using both bibliometric analysis and content analysis. Our results indicate that the number of publications per year has increased year by year, with a particularly rapid increase after 2015. Institutions and researchers from China and the USA publish the greatest number of papers and contribute the most to this field. By analyzing the research progress in this field, we also find that the protection and restoration of freshwater aquaculture environments has received attention since as early as 1990, such as the application of constructed wetlands and recirculating aquaculture systems. Recently, researchers have increasingly focused on the use of microbial communities in remediation. Furthermore, vanRijn, J's papers are of great value to the research in this field. In content analysis, the application of primary technologies, including plant selection, aquatic animals, microorganisms, and biological filtration and purification equipment, as well as ecological engineering technologies with combinations of various types of organisms, is described to improve the effectiveness and efficiency of remediation. The performance, advantages, disadvantages, or limitations and prospects of these technology applications are analyzed in detail. By comparison, ecological engineering is shown to be the best remediation technology, being most comprehensive, and well-established. Taken together, this paper composes and summarizes existing work in this field, and provides guidance for future research on the improvement of existing technologies and the development of new technologies, with the aim of enhancing remediation capability, improving ecological sustainability and ensuring economic viability. [ABSTRACT FROM AUTHOR]

This review paper presents a comprehensive bibliometric analysis of the global scientific research pertaining to carbapenem-resistant Acinetobacter baumannii (CRAB) from the years 1996 to 2023. The review employs a systematic approach to evaluate the trends, patterns, and collaborative networks within the CRAB research landscape, shedding light on its substantial global health implications. An analysis of the Scopus database reveals that the earliest publication within the CRAB research domain dates back to 1996. By conducting a meticulous examination of publication output, citation trends, author affiliations, and keyword distributions, this paper provides valuable insights into the evolution of research themes and the emergence of new areas of interest concerning CRAB. The findings of this bibliometric analysis prominently feature the most influential author within this field, namely, Higgins PG, who has contributed a remarkable 39 documents to CRAB research. It is noteworthy that China leads in terms of the quantity of published research articles in this domain, whereas the United States occupies the foremost position about citations within the CRAB research sphere. Furthermore, a more profound exploration of the data yields a heightened understanding of the current status of CRAB research, emphasizing potential avenues for future investigations and underscoring the imperative need for collaborative initiatives to address the challenges posed by this antibiotic-resistant pathogen. [ABSTRACT FROM AUTHOR]

Despite the growing relevance of the Asian context in foreign entry mode choice (FEMC) research over the previous two decades, the underrepresentation of authors affiliated with emerging contexts is surprising, necessitating a granular investigation. Using advanced bibliometric techniques, this study first highlights the representativeness gap of authors affiliated with Asian economies and then maps the conceptual and intellectual structure of FEMC research. The findings indicate that while issues related to emerging Asian contexts have gained traction, the authors affiliated with Asian institutes are highly under-represented. The analysis of 982 papers retrieved from the Web of Science and published between 2001 and 2021 shows that while North American (30%) and European affiliations (43%) account for 73% of author appearances, Asian affiliations (7.9%) are underrepresented, except for China. Given the strong link between context-sensitivity and affiliation, researchers affiliated with emerging contexts may be better positioned to portray the context-sensitivity of the FEMC construct by granularly investigating the intricacies and subtleties that are unique to these contexts. Insights from conceptual thematic analysis point to research gaps and opportunities. The practical implications for the Asian context lie in giving voice to authors from these contexts to capture the contextsensitivity of the FEMC construct. [ABSTRACT FROM AUTHOR]

Fireflies are groups of the Coleoptera order and the Lampyridae family. Fireflies are typically classified as nocturnal insects, however some are diurnal, and others have mixed nocturnal and diurnal characteristics. They are also known as luminescent insects due to their ability to emit light. Bibliometric analysis is a popular and rigorous method for discovering and analyzing enormous volumes of scientific data. Therefore, the objective of this study is to present overview and guidelines in studies related to firefly research worldwide from 2000 to 2021 using bibliometric analysis to provide researchers and scholars around the world an overview of results and trends in firefly research. A textual query on three databases; Scopus (289 papers), Web of Science (303 papers), and PubMed (541 papers) using the term "Fireflies Coleoptera Lampyridae" was performed on 30 August 2021 retrieving 1133 scholarly papers from 2000 to 2021 related to firefly studies for in-depth analysis. Bibliometric analysis were performed using Rstudio software version 4.1.1 and biblioshiniy for bibliometrix to visualize and analyze trends of firefly research. This bibliometric analysis was analyzed the annual scientific publication growth, the most productive authors, most frequent word has been using, most famous journal name, and which countries has highest collaboration with other country in firefly research. According to the findings of the analysis, there is significant inconsistency in global trends in annual scientific production, with the number of publications increasing and decreasing. In firefly research, according to the findings has show the most relevant authors is Fu X (Scopus), Fu XH (WoS), and Hosseinkhani S (PubMed). Moreover, the most relevant journals articles in fireflies studies is Zootaxa (Scopus & WoS), and Photochemical & Photobiological Sciences: Official Journal Of The European Photochemistry Association And The European Society For Photobiology (PubMed). Futhermore, the most frequently utilized keywords in fireflies study is lampyridae, firefly, bioluminescence, animals and fireflies. China and USA is the most highest collaboration among others countries in fireflies research. This research can help researchers or academics who are new to firefly research by providing information on which publications and authors to refer when performing firefly research. [ABSTRACT FROM AUTHOR]

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Mounting evidence suggests microbiota dysbiosis augment autoimmune response. This study aims to provide a systematic overview of this research field in SLE through a bibliometric analysis. Methods: We conducted a comprehensive search and retrieval of literature related to microbial researches in SLE from the Web of Science Core Collection (WOSCC) database. The retrieved articles were subjected to bibliometric analysis using VOSviewer and Bibliometricx to explore annual publication output, collaborative patterns, research hotspots, current research status, and emerging trends. Results: In this study, we conducted a comprehensive analysis of 218 research articles and 118 review articles. The quantity of publications rises annually, notably surging in 2015 and 2018. The United States and China emerged as the leading contributors in microbial research of SLE. Mashhad University of Medical Sciences had the highest publication outputs among the institutions. Frontiers in Immunology published the most papers. Luo XM and Margolles A were the most prolific and highly cited contributors among individual authors. Microbial research in SLE primarily focused on changes in microbial composition, particularly gut microbiota, as well as the mechanisms and practical applications in SLE. Recent trends emphasize "metabolites," "metabolomics," "fatty acids," "T cells," "lactobacillus," and "dietary supplementation," indicating a growing emphasis on microbial metabolism and interventions in SLE. Conclusion: This study provides a thorough analysis of the research landscape concerning microbiota in SLE. The microbial research in SLE mainly focused on three aspects: microbial dysbiosis, mechanism studies and translational studies (microbiota-based therapeutics). It identifies current research trends and focal points, offering valuable guidance for scholars in the field. [ABSTRACT FROM AUTHOR]

Laminated composite plates have become a crucial point of interest in the industry, with the need to ensure sustained and stable structures throughout the plates' lifespan. This study conducted a bibliometric analysis using the Scopus database, gathering 8221 documents for further scrutiny based on the linked meta-data. Utilizing the VOS viewer software version 1.6.19, maps were generated from scientific publishing network data, illustrating connections between researchers' nations and keywords. The investigation into co-occurring phrases associated with laminated composite plates employed author keywords. The results reveal a significant and close relationship among top authors, suggesting a strong research connection, with the United States and China leading the field. Top cited documents and keyword correlations are examined to gauge current research interests. These critical reviews serve as essential resources for scholars and practitioners in the field. Additionally, the review discusses the advancements in and practical applications of different theories for laminated composite plates, with a focus on a bibliometric study using the Scopus database. This paper categorizes models within the context of an equivalent single-layer laminate, analyzing variations in established theories and methodologies for modeling laminated composite plates to offer a nuanced understanding of approaches and assessments in this field. [ABSTRACT FROM AUTHOR]

Objective: This study aims to visualize the trends and hotspots in the research of "ferroptosis in PD" and "pyroptosis in PD" through bibliometric analysis from the past to 2024. Methods: Literature was retrieved from the Web of Science Core Collection (WoSCC) from the past to February 16, 2024, and bibliometric analysis was conducted using Vosviewer and Citespace. Results: 283 and 542 papers were collected in the field of "ferroptosis in PD" and "pyroptosis in PD." The number of publications in both fields has increased yearly, especially in "ferroptosis in PD," which will become the focus of PD research. China, the United States and England had extensive exchanges and collaborations in both fields, and more than 60% of the top 10 institutions were from China. In the fields of "ferroptosis in PD" and "pyroptosis in PD," the University of Melbourne and Nanjing Medical University stood out in terms of publication numbers, citation frequency, and centrality, and the most influential journals were Cell and Nature, respectively. The keyword time zone map showed that molecular mechanisms and neurons were the research hotspots of "ferroptosis in PD" in 2023, while memory and receptor 2 were the research hotspots of "pyroptosis in PD" in 2023, which may predict the future research direction. Conclusion: This study provides insights into the development, collaborations, research themes, hotspots, and tendencies of "ferroptosis in PD" and "pyroptosis in PD." Overall situation of these fields is available for researchers to further explore the underlying mechanisms and potential treatments. [ABSTRACT FROM AUTHOR]

Background: Mild cognitive impairment (MCI) is commonly defined as a transitional subclinical state between normal aging and dementia. A growing body of research indicates that health behaviors may play a protective role against cognitive decline and could potentially slow down the progression from MCI to dementia. The aim of this study is to conduct a bibliometric analysis of literature focusing on health behaviors and MCI to summarize the factors and evidence regarding the influence of health behaviors on MCI. Methods: The study performed a bibliometric analysis by retrieving publications from the Science Citation Index and Social Sciences Citation Index subdatabases within the Web of Science Core Collection. Utilizing VOSviewer and CiteSpace software, a total of 2,843 eligible articles underwent co-citation, cokeywords, and clustering analyses. This methodology aimed to investigate the current status, trends, major research questions, and potential future directions within the research domain. Results: The bibliometric analysis indicates that research on healthy behaviors in individuals with MCI originated in 2002 and experienced rapid growth in 2014, reflecting the increasing global interest in this area. The United States emerged as the primary contributor, accounting for more than one-third of the total scientific output with 982 articles. Journals that published the most articles on MCI-related health behaviors included "Journal of Alzheimer's Disease," "Neurobiology of Aging," "Frontiers in Aging Neuroscience," and other geriatricsrelated journals. High-impact papers identified by VOSviewer predominantly cover concepts related to MCI, such as diagnostic criteria, assessment, and multifactorial interventions. Co-occurrence keyword analysis highlights five research hotspots in health behavior associated with MCI: exercise, diet, risk factors and preventive measures for dementia, cognitive decline-related biomarkers, and clinical trials. Conclusion: This study provides a comprehensive review of literature on health behavior in individuals with MCI, emphasizing influential documents and journals. It outlines research trends and key focal points, offering valuable insights for researchers to comprehend significant contributions and steer future studies. [ABSTRACT FROM AUTHOR]

Background: Interleukin17 (IL17) is an important cytokine in host defense at mucosal surfaces and also mediates many autoimmune diseases, including rheumatoid arthritis (RA). In recent years, many types of research relevant to the structure and function of IL17 have been identified. However, there is no bibliometric analysis in this research field. This study aims to explore the history, research hotspots, and emerging trends of IL17 from the perspective of the structure and function dynamics. Methods: Articles relevant to IL17 in the last two decades were retrieved through the Web of Science Core Collection (WoSCC) database. The bibliometric analysis was performed by VOSview. Results: A total of 882 papers in this research were analyzed from 65 countries, and the rate of published articles has increased from 2008 annually, with the USA, China, and Germany leading the research effort. Frontiers in Immunology has significantly impacted research in this field and the University of Pittsburgh was the leading institution. Gaffen, Sarah L. from the University of Pittsburgh was the most productive researcher in this field and Papp Ka from the Probity Medical Research Incorporate of Canada is the most co-cited author. The analysis of keywords showed that inflammation, expression, Th17 cells, and cytokines were the main hotspots and frontier directions of IL17. The trend of clinical application in the future is the development of new therapy drugs based on the structure of IL17 or IL17 signaling pathway molecular. Conclusions: Our research summarized the developments and research trends of IL17 and would help researchers understand the research status of IL17 and provide a reference for future researchers as soon as possible. [ABSTRACT FROM AUTHOR]

Background: Autoimmune diseases have always been one of the difficult diseases of clinical concern. Because of the diversity and complexity of its causative factors, unclear occurrence and development process and difficult treatment, it has become a key disease for researchers to study. And the disease explored in this paper, anti-NMDA encephalitis, belongs to a common type of autoimmune encephalitis. However, the quality of articles and research hotspots in this field are not yet known. Therefore, in this field, we completed a bibliometric and visualization analysis from 2005 to 2023 in order to understand the research hotspots and directions of development in this field. Materials and methods: We searched the SCI-expanded databases using Web of Science's core databases on January 22, 2024 and used tools such as VOS viewer, Cite Space, and R software to visualize and analyze the authors, countries, journals, institutions, and keywords of the articles. Results: A total of 1,161 literatures were retrieved and analyzed in this study. China was the country with the most total publications, and USA and Spain were the most influential countries in the field of anti-NMDA encephalitis. University of Pennsylvania from USA was the institution with the highest number of publications. While Dalmau Josep is the most prolific, influential and contributing author who published one of the most cited articles in Lancet Neurology, which laid the foundation for anti-NMDA encephalitis research, the top three appearances of keyword analysis were: "antibodies", "diagnosis", and "autoimmune encephalitis." Conclusion: Bibliometric analysis shows that the number of studies on anti-NMDA encephalitis is generally increasing year by year, and it is a hot disease pursued by researchers. USA and Spain are leading in the field of anti-NMDA encephalitis, while China should continue to improve the quality of its own research. The suspected causes of anti-NMDA encephalitis other than ovarian teratoma and herpes simplex, the specific clinical manifestations that are not masked by psychiatric symptoms, the diagnostic modalities that are faster and more accurate than antibody tests, and the improvement of treatment modalities by evaluating prognosis of various types of patients are the hotspots for future research. [ABSTRACT FROM AUTHOR]

Background: Acupuncture is a widely used clinical treatment method, and studies have confirmed its therapeutic effects on stroke patients. It can also reduce the burden on patients and society. Acupuncture treatment is a complementary and preventive treatment for stroke. However, there has yet to be a visual bibliometric analysis of the field of acupuncture for stroke rat models. This study explores future trends, research hotspots, and frontiers in acupuncture for stroke rat models over the past 20 years through investigation and visualization. Methods: We collected literature data on acupuncture treatment of stroke in rats from the Web of Science Core Collection (WOSCC) database from January 1, 2004, to December 31, 2023. Import into CiteSpace (version 6.2.R4) and RStudio for analysis by author, country/region, affiliation, annual publication, keywords, and journal visualization. Results: A total of 379 articles were retrieved, including articles from 16 countries, 258 research institutions, and 123 academic journals. The countries and institutions with the most publications were the People's Republic of China (338) and the Fujian University of Traditional Chinese Medicine (43). Tao, Jing had the highest number of co-citations (144). The keywords and co-citation clustering show the main research directions in the field, including "artery occlusion," "neural regeneration," "stimulation," "rapid tolerance," "receptor," "signaling pathway," "apoptosis," "oxidative stress," "inflammatory response," "endogenous neurogenesis," "tolerance of local cerebral ischemic tissues," "proliferation of reactive astrocytes" and "neuroprotective effect." The intervention combines classical acupuncture treatment and modern technology (electricity) with electroacupuncture as a new intervention modality. Conclusion: This study demonstrates the increasing research on acupuncture for treating stroke in rat models. The country/region with the most publications is the People's Republic of China. However, international cooperation still needs to be improved, and future researchers must strengthen international cooperation. In addition, in future studies, researchers should improve the overall quality of research results in this area and enhance research protocols. [ABSTRACT FROM AUTHOR]

Purpose: With the rapid development of immunotherapy, cancer treatment has entered a new phase. Medical imaging, as a primary diagnostic method, is closely related to cancer immunotherapy. However, until now, there has been no systematic bibliometric analysis of the state of this field. Therefore, the main purpose of this article is to clarify the past research trajectory, summarize current research hotspots, reveal dynamic scientific developments, and explore future research directions. Patients and Methods: A comprehensive search was conducted on the Web of Science Core Collection (WoSCC) database to identify publications related to immunotherapy specifically for the medical imaging of carcinoma. The search spanned the period from the year 2003 to 2023. Several analytical tools were employed. These included CiteSpace (6.2.4), and the Microsoft Office Excel (2016). Results: By searching the database, a total of 704 English articles published between 2003 and 2023 were obtained. We have observed a rapid increase in the number of publications since 2018. The two most active countries are the United States (n=265) and China (n=170). Pittock, Sean J and Abu-sbeih, Hamzah are very concerned about the relationship between cancer immunotherapy and medical images and have published more academic papers (n = 5; n = 4). Among the top 10 co-cited authors, Topalian Sl (n=43) cited ranked first, followed by Graus F (n=40) cited. According to clustering, timeline, and burst word analysis, the results show that the current research focus is on "MRI", "deep learning", "tumor microenvironment" and so on. Conclusion: Medical imaging and cancer immunotherapy are hot topics. The United States is the country with the most publications and the greatest influence in this field, followed by China. "MRI", "PET/PET-CT", "deep learning", "immune-related adverse events" and "tumor microenvironment" are currently hot research topics and potential targets. [ABSTRACT FROM AUTHOR]

Background: Colorectal cancer (CRC)is the third most common cancer in the world and the second leading cause of cancer-related deaths, and over the past two decades, many of these researchers have provided a substantial amount of important information on the role of gut microbes in the development and progression of CRC. A causal relationship between the presence of specific microorganisms and CRC development has also been validated. Although a large number of papers related to this area have been published, no bibliometric study has been conducted to review the current state of research in this area and to highlight the research trends and hotspots in this area. This study aims to analyze the current status and future research trends of gut microbiota and CRC through bibliometric analysis. Methods: Publications from 2001 to 2022 were retrieved from the Web of Science Core Collection database and screened according to inclusion criteria. VOSviewer and CiteSpace software were used to visualize the research trends in this field, including the analysis of title, country, institution, author, number of publications, year of publication, number of citations, journal, and H-index. Results: A total of 863 studies were eventually identified, and the articles retrieved were cited an average of 44.85 times each. The number of publications on this topic has been increased steadily since 2011. China and the USA have made the largest contribution in the field. FRONTIERS IN MICROBIOLOGY is the top productive journal with 26 papers, and Gut journal has the highest average citation (167.23). Shanghai Jiao Tong University is the most contributive institution. Professor Yu J, Sung, Joseph J. Y and Fang JY are the most productive authors in this field. Keyword co-occurrence analysis showed that the terms of "'Gut Microbiota", "Colorectal Cancer", "Inflammation", "Probiotic" and "Fusobacterium Nucleatum" were the most frequent, which revealed the research hotpots and trends in this field. Conclusions: There has been a growing number of publications over the past two decades according to the global trends. China and the USA still maintained the leading position in this field. However, collaboration between institutions needs to be strengthened. It's commended to pay attention to the latest hotspots, such as "F. nucleatum" and "probiotics". This bibliometric analysis evaluates the scope and trends of gut microbiota and CRC, providing a useful perspective on current research and future directions for studying the link between the gut microbiota and CRC. [ABSTRACT FROM AUTHOR]

Due to its unique structure and excellent purification efficiency (e.g., 98% for organic matter and between 94 and 100% for nutrients), multi-soil-layering (MSL) has emerged as an efficient eco-friendly solution for wastewater treatment and environmental protection. Through infiltration-percolation, this soil-based technology allows pollutants to move from the MSL upper layers to the outlet while maintaining direct contact with its media, which helps in their removal via a variety of physical and biochemical mechanisms. This paper attempts to comprehensively evaluate the application of MSL technology and investigate its progress and efficacy since its emergence. Thus, it will attempt via a bibliometric analysis using the Web of Science database (from 1993 to 1 June 2022) related to MSL technology, to give a clear picture of the number of publications (70 studies), the most active academics, and countries (China with 27 studies), as well as collaborations and related topics. Furthermore, through hybrid combinations, pollutant removal processes, MSL effective media, and the key efficiency parameters, this paper review will seek to provide an overview of research that has developed and examined MSL since its inception. On the other hand, the current review will evaluate the modeling approaches used to explore MSL behavior in terms of pollutant removal and simulation of its performance (R2 > 90%). However, despite the increase in MSL publications in the past years (e.g., 13 studies in 2021), many studies are still needed to fill the knowledge gaps and urging challenges regarding this emerging technology. Thus, recommendations on improving the stability and sustainability of MSLs are highlighted. [ABSTRACT FROM AUTHOR]

Simple Summary: Farm animal welfare research conducted in China is relatively less accessed and unknown outside of the country, which might create the impression that farm animal welfare receives limited attention in China. This paper aims to offer a comprehensive review of the existing Chinese farm animal welfare literature. CiteSpace software was employed for the analysis and visualization of various aspects of the literature, including the quantity, species, authors, institutions, journals, and keywords. This process helped reveal the research trends, hotspots, and frontiers in the field. The findings from this bibliometric analysis strongly indicate that farm animal welfare is a subject of considerable interest and research activity in China. Farm animal welfare research conducted in China is not commonly accessed or known outside of China, which may lead to the assumption that farm animal welfare receives relatively little attention in China. Therefore, a bibliometric analysis was conducted on the existing Chinese farm animal welfare literature to provide robust evidence to refute this assumption. A total of 1312 peer-reviewed Chinese studies on farm animal welfare published between March 1992 and June 2023 were retrieved from the Web of Science (WoS) and the China National Knowledge Infrastructure (CNKI) database. CiteSpace software was used to analyze and visualize the number, species, authors, institutions, journals, and keywords of the papers. In China, farm animal welfare research has gone through the processes of an early stage (1992–2001), rapid-growth stage (2002–2007), and mature stage (2008–present), and the scale of research continues to grow. Notably, swine and chickens have received priority attention in this area. A Matthew effect was observed for authors and institutions, with relatively little collaboration among authors and institutions. Most of the papers were published in a small number of journals, with an apparent agglomeration characteristic. The research hotspots, summarized as "feed and diet", "environmental impacts and control", "integrated rearing management", "injury and disease", "behavior and technologies for behavior monitoring", "genetic analysis", "welfare during transport and slaughter", "welfare-friendly animal product consumption", "attitudes toward farm animal welfare", and "healthy breeding". The keywords "computer vision", "recognition", "temperature", "precision livestock farming", "laying hen", and "behavior", represent the major research frontiers in the field, which could indicate potential areas of significant future research. The findings of the present bibliometric analysis confirm the fact that farm animal welfare is a field of interest in China. Farm animal welfare research in China tends to be pragmatic, with a strong emphasis on enhancing growth and production performance, as well as product quality, rather than solely concentrating on improving farm animal welfare. This paper provides insightful references that researchers can use to identify and understand the current status and future direction of the farm animal welfare field in China. [ABSTRACT FROM AUTHOR]

Introduction: Network pharmacology has emerged as a forefront and hotspot in anti-cancer. Traditional anti-cancer drugs are limited by the paradigm of "one cancer, one target, one drug," making it difficult to address the challenges of recurrence and drug resistance. However, the main advantage of network pharmacology lies in its approach from the perspective of molecular network relationships, employing a "one arrow, multiple targets" strategy, which provides a novel pathway for developing anti-cancer drugs. This study employed a bibliometric analysis method to examine network pharmacology's application and research progress in cancer treatment from January 2008 to May 2023. This research will contribute to revealing its forefront and hotspots, offering new insights and methodologies for future investigations. Methods: We conducted a literature search on network pharmacology research in anti-cancer (NPART) from January 2008 to May 2023, utilizing scientific databases such as Web of Science Core Collection (WoSCC) and PubMed to retrieve relevant research articles and reviews. Additionally, we employed visualization tools such as Citespace, SCImago Graphica, and VOSviewer to perform bibliometric analysis. Results: This study encompassed 3,018 articles, with 2,210 articles from WoSCC and 808 from PubMed. Firstly, an analysis of the annual national publication trends and citation counts indicated that China and the United States are the primary contributing countries in this field. Secondly, the recent keyword analysis revealed emerging research hotspots in "tumor microenvironment," "anti-cancer drugs," and "traditional Chinese medicine (TCM). "Furthermore, the literature clustering analysis demonstrated that "calycosin," "molecular mechanism," "molecular docking," and "anti-cancer agents" were widely recognized research hotspots and forefront areas in 2023, garnering significant attention and citations in this field. Ultimately, we analyzed the application of NPART and the challenges. Conclusion: This study represents the first comprehensive analysis paper based on bibliometric methods, aiming to investigate the forefront hotspots of network pharmacology in anti-cancer research. The findings of this study will facilitate researchers in swiftly comprehending the current research trends and forefront hotspots in the domain of network pharmacology in cancer research. [ABSTRACT FROM AUTHOR]

Faced with substantial environmental, societal, and economic challenges, the matters of rural sustainability and land use have emerged as pivotal global concerns. Amidst the rapid phenomenon of urbanization, the escalating requisites for sustenance, energy, and natural resources have engendered profound pressure upon rural landscapes and ecosystems. The attainment of sustainability within rural regions assumes a paramount role, encompassing not only the advancement of these rural domains but also holding pivotal significance in addressing critical global concerns such as climate change, biodiversity depletion, and the eradication of poverty. In order to gain a thorough understanding of the implications associated with rural sustainability and land use, this study undertakes a bibliometric analysis of 1746 articles sourced from the Web of Science database. The analysis unveils a multitude of pivotal revelations. Primarily, the domain exhibits a conspicuous trajectory of expansion in publications spanning the period from 1990 to 2023, thereby alluding to a substantial reservoir of potential for subsequent advancement. Secondly, high-frequency keywords encompass sustainability, land use, agriculture, ecosystem services, and China. Thirdly, the field encompasses four primary research directions, namely the impact of rural land use and land cover changes on biodiversity, adaptive capacity, and vulnerability in rural sustainable development; the interplay between rural land use changes and rural agricultural development; and land management for rural sustainability. Fourthly, the evolution of research hotspots focuses on three main areas: rural sustainability and biodiversity conservation and ecosystem services, rural sustainability and land management and impacts, and the impacts of climate change and human activities on rural sustainability. Finally, future research should focus on sustainable multifunctional agriculture and rural land management, continue to pay attention to the social dimensions of rural sustainability, and emphasize the role of ecosystem services and natural capital in sustainable rural development. The results of this study can provide a reference for grasping the current situation, research directions, and development trends in the field of rural sustainability and land use. [ABSTRACT FROM AUTHOR]

Purpose: This study aims to help researchers master the most active hotspots and trends quickly through bibliometric analysis in the field of dysmenorrhea.Methods: We retrieved literature on Web of Science from 2001 to 2021, and bibliometric analysis software CiteSpace was used in combination with VOSviewer.Results: We finally acquired 944 papers and an upward trend in articles continued in this field overall. Through the map, China contributed the most, followed by the USA and Turkey. For institutions, Beijing University of Chinese Medicine in China contributed the most, followed by National Yang-Ming University in Taiwan, China. Hsieh JC and Hellman KM were both the most prolific authors with 14 articles. Five major research groups, respectively, with Hsieh JC, Hellman KM, Zhu J, Liang F and Dun W were the key group. Dawood MY was the most dominant author and most frequently cited author. The Cochrane Database of Systematic Reviews Journal was the most productive, and the Fertility and Sterility Journal was the most cited. Advances in pathogenesis and management for primary dysmenorrhea written by Dawood MY was most cited and influential. Pathophysiology, the potential central mechanism, syndrome, evaluation index, diagnosis of adenomyosis-associated dysmenorrhea, treatment, etc., were the main trends and hotspots.Conclusion: Dysmenorrhea research has received a lot of attention from scholars. Strengthening international cooperation may promote the development of this field. The pathophysiology of dysmenorrhea, its impact on public health and its treatment are current research hotspots and are likely to be the focus of future study. [ABSTRACT FROM AUTHOR]

Aims: The aim of this study was to analyse the status, hotspots and trends of research on oral care for the elderly in mainland China in the past 20 years through bibliometrics, which aims to provide new ideas and targets for future clinical work and research. Design: Bibliometric analysis. Methods: Relevant literature was retrieved from China National Knowledge Infrastructure, Wanfang, China Science and Technology Journal Database, Web of Science and PubMed. NoteExpress, Co‐Occurrence and CiteSpace were used to analyse bibliometric features in terms of year of publication, journal of publication, authors, institution and keywords. Results: A total of 716 related articles were obtained. The number of publications shows an increasing trend over time, only 2017–2021; 309 papers were published, accounting for 43.2% of the total number of publications. A total of 238 articles were published in Science Citation Index journals or Chinese core journals, accounting for 33.2% of the total number of articles. The study of oral health‐related quality of life in the elderly is a hot research topic. There is a lack of research on the elderly living in elderly care facilities. [ABSTRACT FROM AUTHOR]

Background: Small-cell lung cancer (SCLC) is a recalcitrant tumor with a poor prognosis. With the rise of SCLC research in the past decade, this study aims to analyze the foundation and frontiers of SCLC research through bibliometric analysis. Methods: Relevant publications from the Web of Science Core Collection were retrieved on January 3, 2022. R package bibliometrix and EXCEL2019 were used to analyze quantitative variables. Bibliometric mapping was constructed by VOS viewer and CiteSpace software to visualize citation, co-authorship, cooccurrence, and co-citation analysis of countries/regions, organizations, authors, references, and keywords. Results: A total of 2,361 publications related to SCLC were identified with the total amount of articles steadily increasing, where China is the most productive country with 859 papers. Scholars and organizations from the United States, China, and Europe are primary sources of this research, among which the University of Texas MD Anderson Cancer Center made the most contribution to the field with 122 papers. Lung Cancer published the highest number of SCLC-related articles with a total of 121, while the Journal of Thoracic Oncology received the most citations totaling 3,098. Rudin, Charles M., and Sage, Julien are the most creative author. Leora, Horn, 2018, New Engl J Med and Rudin, Charles M., Nat Genet, 2012 can be categorized as classic literature owing to their high citations or strong sigma value. “Heterogeneity & Subtypes” and “Immunotherapy” may be the new frontiers in the SCLC domain. Conclusion: Research on SCLC showed an upward trend based on the current global situation. Moreover, the current scope of collaboration in SCLC research is chiefly regional, which should further focus on transnational cooperation in the future. More attention should be devoted to “Heterogeneity & Subtypes” and “Immunotherapy”, which will be the hotspots in future research. [ABSTRACT FROM AUTHOR]

Objectives: The aim of this study was to conduct a bibliometric analysis of the literature on stem cell treatment for spinal cord injury to gain an intuitive understanding of how the field is progressing, discover topics of interest, and determine what development trends are emerging in this field. Background: Spinal cord injury and its complications often cause an enormous economic burden, and postinjury repair and treatment have always been challenging in clinical and scientific research. Stem cell therapy for spinal cord injury can prevent immune rejection and induce the release of neuroprotective and anti-inflammatory factors to reduce the production of stress-related proteins, reactive oxygen species, and inflammatory reactions. Methods: We analyzed the number and quality of publications in the field of stem cell therapy in spinal cord injury between 2018.01.01 and 2023.06.30 in the core collection database of Web of Science. CiteSpace and VOSviewer were used to sort and summarize these studies by country, institution, authors' publications, and collaborative networks. In addition, the research topics of interest were identified and summarized. Results: This study ultimately included 2,150 valid papers, with the number of publications showing a gradual upward trend. The country, institution, author and journal with the greatest number of publications and citations are China, the Chinese Academy of Sciences, Dai JW, and the International Journal of Molecular Sciences, respectively. The top three high-frequency keyword clusters were hereditary paraplegia, reactive astrocytes and tissue engineering. Conclusion: With the help of visual analysis, we identified general trends and research topics of interest in the field of spinal cord injury over the last 5 years. Our findings suggest that stem cell transplantation for spinal cord injury and exosome therapy may be a focus of future research. This study provides a foundation for future research on stem cell therapy as well as clinical efforts in this field. [ABSTRACT FROM AUTHOR]

Numerous studies have highlighted the implication of oral microbiota in various cancers. However, no bibliometric analysis has been conducted on the relationship between oral microbiota and cancer. This bibliometric analysis aimed to identify the research hotspots in oral microbiota and cancer research, as well as predict future research trends. The literature published relating to oral microbiota and cancer was searched from the Web of Science Core Collection database (WoSCC) from 2013 to 2022. VOSviewer or Citespace software was used to perform the bibliometric analysis, focusing on countries, institutions, authors, journals, keywords and references. A total of 1516 publications were included in the analysis. The number of publications related oral microbiota and cancer increased annually, reaching its peak in 2022 with 287 papers. The United States (456) and China (370) were the countries with the most publications and made significant contributions to the field. Sears CL and Zhou XD were the most productive authors. The high frequency of keywords revealed key topics, including cancer (colorectal cancer, oral cancer), oral microbiota (Fusobacterium nucleatum, Porphyromonas gingivalis), and inflammation (periodontal disease). The latest trend keywords were F. nucleatum, dysbiosis, prognosis, tumor microenvironment, gastric microbiota, complications and survival, suggesting a new hotspot in the field of oral microbiota and cancer. Our study provides a comprehensive analysis of oral microbiota and cancer research, revealing an increase in publications in recent years. Future research directions will continue to focus on the diversity of oral microbiota impacted by cancers and the underlying mechanism connecting them, providing new ideas for targeted therapy of tumorigenesis. [ABSTRACT FROM AUTHOR]

Background: Mesenchymal stem cells (MSCs) have important research value and broad application prospects in liver diseases. This study aims to comprehensively review the cooperation and influence of countries, institutions, authors, and journals in the field of MSCs in liver diseases from the perspective of bibliometrics, evaluate the clustering evolution of knowledge structure, and discover hot trends and emerging topics. Methods: The articles and reviews related to MSCs in liver diseases were retrieved from the Web of Science Core Collection using Topic Search. A bibliometric study was performed using CiteSpace and VOSviewer. Results: A total of 3404 articles and reviews were included over the period 2001-2021. The number of articles regarding MSCs in liver diseases showed an increasing trend. These publications mainly come from 3251 institutions in 113 countries led by China and the USA. Li L published the most papers among the publications, while Pittenger MF had the most co-citations. Analysis of the most productive journals shows that most are specialized in medical research, experimental medicine and cell biology, and cell & tissue engineering. The macroscopical sketch and micro-representation of the whole knowledge field are realized through co-citation analysis. Liver scaffold, MSC therapy, extracellular vesicle, and others are current and developing areas of the study. The keywords "machine perfusion", "liver transplantation", and "microRNAs" also may be the focus of new trends and future research. Conclusions: In this study, bibliometrics and visual methods were used to review the research of MSCs in liver diseases comprehensively. This paper will help scholars better understand the dynamic evolution of the application of MSCs in liver diseases and point out the direction for future research. [ABSTRACT FROM AUTHOR]

The continuous increase in the volume of geospatial data has led to the creation of storage tools and the cloud to process data. Google Earth Engine (GEE) is a cloud-based platform that facilitates geoprocessing, making it a tool of great interest to the academic and research world. This article proposes a bibliometric analysis of the GEE platform to analyze its scientific production. The methodology consists of four phases. The first phase corresponds to selecting "search" criteria, followed by the second phase focused on collecting data during the 2011 and 2022 periods using Elsevier's Scopus database. Software and bibliometrics allowed to review the published articles during the third phase. Finally, the results were analyzed and interpreted in the last phase. The research found 2800 documents that received contributions from 125 countries, with China and the USA leading as the countries with higher contributions supporting an increment in the use of GEE for the visualization and processing of geospatial data. The intellectual structure study and knowledge mapping showed that topics of interest included satellites, sensors, remote sensing, machine learning, land use and land cover. The co-citations analysis revealed the connection between the researchers who used the GEE platform in their research papers. GEE has proven to be an emergent web platform with the potential to manage big satellite data easily. Furthermore, GEE is considered a multidisciplinary tool with multiple applications in various areas of knowledge. This research adds to the current knowledge about the Google Earth Engine platform, analyzing its cognitive structure related to the research in the Scopus database. In addition, this study presents inferences and suggestions to develop future works with this methodology. [ABSTRACT FROM AUTHOR]