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This paper analyzes and discusses the potential and limits of using Facebook data to analyse spatial-temporal urban rhythms and city centrality through the availability of services and retail. During September 2020, we harvested Facebook Places data using Graph API for our pilot area consisting in the city of Brno. Specifically, we focused on the spatial distribution of 'Food & Beverage', 'Shopping & Retail' and 'Medical & Health' categories, and their associated opening hours. The paper provides a detailed description of data collection and post-processing among possible analysis methods and visualizations presented in the context of our case study. The study focuses on inter-urban structures and urban rhythms through the analysis of opening hours of retail and services. We also discuss the benefits and potential problems associated with the use of these data. [ABSTRACT FROM AUTHOR]