Search

Your search keyword '"Kang, Wenyuan"' showing total 3 results
Start Over Author "Kang, Wenyuan" Publication Year Range Last 50 years Publisher royal society of chemistry
3 results on '"Kang, Wenyuan"'

3. Charge designable and tunable GFP as a target pH-responsive carrier for intracellular functional protein delivery and tracing.

Author

Hu, Shanfang, Chen, Xiaoye, Lei, Chunyang, Tang, Rui, Kang, Wenyuan, Deng, Honghua, Huang, Yan, Nie, Zhou, and Yao, Shouzhuo

Subjects
GREEN fluorescent protein, INTRACELLULAR tracking, PH effect, INHIBITION of cellular proliferation, HELA cells
Abstract

A charge designable and tunable green fluorescent protein (GFP)-based protein delivery strategy was proposed. The acquired His29GFP selectively permeates the cell membrane at a target pH of 6.5 and escapes from the endosome efficiently. The delivered RNase A caused substantial mRNA degradation in HeLa cells, and proliferation inhibition in different cell lines and a 3D tumor model at pH 6.5. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results