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Your search keyword '"Yuanlin Dong"' showing total 4 results
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4 results on '"Yuanlin Dong"'

4. Nitrous Oxide Plus Isoflurane Induces Apoptosis and Increases β-Amyloid Protein Levels.

Author

Yu Zhen, Yuanlin Dong, Xu Wu, Zhipeng Xu, Yan Lu, Yiying Zhang, David Norton, Ming Tian, Shuren Li, and Zhongcong Xie

Subjects
*ANESTHETICS, *NITROGEN oxides, *ISOFLURANE, *APOPTOSIS, *NEURONS, *AMYLOID beta-protein precursor, *AMYLOID beta-protein, *MEDICAL research, *LABORATORY mice
Abstract

The article focuses on a study which evaluates the effects of nitrous oxide and isoflurane on apoptosis and beta-amyloid levels in human neuroglioma cells and primary neurons from mice. In this study, cells or neurons and conditioned media that are exposed to nitrous oxide and isoflurane are harvested at the end of the treatment. Researchers determine the caspase-3 activation, apoptosis, processing of amyloid precursor protein (APP) and beta-amyloid levels. They conclude that apoptosis can enhance aspartyl protease beta-site APP-cleaving enzyme (BACE) levels to help APP processing.

Published
2009
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