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Purpose. Psychological resilience plays an important role in relieving the psychological distress. However, little is known about its underlying mechanisms. Mental health literacy, an important way to promote mental health, may mediate the effect of psychological resilience on psychological distress. This study aimed to explore the relationship between mental health literacy, psychological resilience, and psychological distress and explore the mediating effect between psychological resilience and psychological distress. Design and Methods. A cross-sectional study design was used. A total of 627 medical students were selected from one university. An electronic questionnaire was administered to collect information on the level of mental health literacy, psychological resilience, and psychological distress. Pearson's correlation analysis was used in analyzing the relationship, and the Bootstrap method was used to test the mediating effects. Findings. Psychological distress significantly negatively correlated with mental health literacy and psychological resilience (P < 0.001). The indirect effect of mental health literacy accounted for 50.43% of the total effect between psychological resilience and psychological distress. Practical Implication. Psychological resilience decreased the level of psychological distress, and this relationship was partially mediated by mental health literacy. These findings showed that efforts aimed at enhancing the mental health literacy may prevent or reduce the prevalence of psychological distress symptoms among college students. [ABSTRACT FROM AUTHOR]

Objective. To explore the effect of Xinyi Biyan Pill in adjuvant treatment of patients with chronic rhinosinusitis (CRS) and its influence on serum inflammatory factors and immune function. Methods. From January 2017 to April 2020, 112 CRS patients admitted to this hospital were randomly divided into the control group (n = 52) and the study group (n = 60). The control group was treated with endoscopic sinus surgery (ESS), after the operation, levofloxacin capsules were taken orally, budesonide nasal spray was given, and the nasal cavity was flushed with normal saline; on the basis of that mentioned above, the study group was treated with Xinyi Biyan Pill orally after the surgery. The clinical efficacy and the symptom relief time of nasal congestion and runny nose, hyposmia, mucosal edema, and vesicles disappearance of the two groups after treatment were observed; the serum inflammatory factors' (C-reactive protein (CRP), interleukin-6 (IL-6), and interleukin-8 (IL-8)) and immune function indexes' (total immunoglobulin E (TIgE), eosinophil cationic protein (ECP), CD3+, CD4+, and CD4+/CD8+) expression levels before and after treatment in the two groups were detected; the recurrence of CRS after 1 year of treatment in the two groups was recorded. Result. After treatment, the total clinical effective rate of the study group (92.98%) was significantly higher than that of the control group (78.00%) (P < 0.05). After treatment, the symptom relief time of nasal congestion and runny nose, hyposmia, mucosal edema, and vesicle disappearance in the study group was shorter than that in the control group (P < 0.05). After treatment, the expression levels of serum CRP, IL-6, and IL-8 in the two groups were significantly lower than those before treatment, and the study group was significantly lower than the control group (P < 0.05). After treatment, the expression levels of serum TIgE and ECP of the two groups were significantly lower than those before treatment, the expression levels of serum CD3+, CD4+, and CD4+/CD8+ of the two groups were significantly higher than those before treatment, and the study group had significant changes compared with the control group (P < 0.05). After 1 year of treatment, the recurrence rate of CRS in the study group (1.79%) was significantly lower than that in the control group (12.00%) (P < 0.05). Conclusion. Xinyi Biyan Pill has a significant clinical effect in adjuvant treatment of CRS patients. It can effectively reduce the expression level of serum inflammatory factors, improve the body's immune function, and prevent short-term recurrence. It is worthy of clinical promotion. [ABSTRACT FROM AUTHOR]

Objective. It remains unknown whether obesity has an effect on the pituitary-thyroid feedback control axis in subclinical hypothyroidism (SCH). We aimed to investigate the association of thyroid homeostasis with obesity in a SCH population. Methods. Our study consisted of a community-based and cross-sectional study from the Epidemiological Survey of Thyroid Diseases in Fujian Province, China. A total of 193 subjects with SCH (90 males and 103 females) without a history of treatment of thyroid disease, such as surgery, radiation, and thyroid hormone or antithyroid medication, were included in the present study. Indices of obesity, including body mass index (BMI), waist circumference (WC), and waist-height ratio (WHtR) were measured. Results. Our results showed that the secretory capacity of the thyroid gland (SPINA-GT) and Jostel's thyrotropin index (TSHI) were negatively correlated with BMI, WC, and WHtR, whereas the reciprocal of the thyrotroph thyroid hormone resistance index (TTSI-1) was positively correlated with BMI (all p < 0.05). After adjustment for age, sex, smoking, iodine status, and glucolipid metabolism, the associations between TSHI, TTSI (reciprocal transformation), and BMI still persisted (all p < 0.05). Conclusions. These results suggest that low levels of thyroid homeostasis indexes may be associated with overall obesity in SCH, rather than central adiposity. [ABSTRACT FROM AUTHOR]

As the core of the port and shipping service supply chain system, the port and shipping companies must urgently solve the problem of how to balance emissions, costs, and benefits with the gradual extension of China's emission control area (ECA) and the stringent emission requirements. From the perspective of system optimization, this research constructs a revenue sharing model of the port and shipping service supply chain and deals with the revenue sharing decision-making problem of the secondary service supply chain after port enterprises and shipping enterprises joining the government subsidy mechanism driven by ECA's policy. Research shows that the government subsidy mechanism directly affects the profit of the port and shipping service supply chain, which is the key factor in implementing the ECA's policy and promoting the emission reduction of the port and shipping enterprises. The revenue sharing of the port and shipping enterprises plays a decisive role in the revenue of the shipping enterprises. Cooperative emission reduction mechanism should be led by port enterprises to promote the balance between revenue and emission reduction in the supply chain system. Results provide a reference for the Chinese government to formulate corresponding incentives and subsidy policy under the new ECA's regulations as well as solving the problems of how to balance emissions reduction and cost improvement for port and shipping enterprises. [ABSTRACT FROM AUTHOR]

Intermodal transportation, as an efficient form of transport organization, is a key technology and means for the logistics industry to balance transport costs and efficiency. How to deeply analyze the key factors constraining the level of development of multimodal transportation in China, building multimodal transportation development evaluation index system and evaluation model, evaluating comprehensively the multimodal transportation development level in China, and putting forward targeted countermeasures is of great practical significance. Based on the hesitant fuzzy multiattribute decision-making method, this paper analyzes the key factors influencing the level of multimodal transportation development from the perspective of sea-rail intermodal transport and further uses the interval number discretization and likelihood deviation maximization multiattribute decision-making method to construct a mixed-data index evaluation model, which is combined with data from 11 provinces (cities) in China. The study shows that there is a big gap among different provinces (cities) in China concerning the level of multimodal transportation development. Besides, the volume of intermodal container transportation and railway mileage are the core factors affecting the level of multimodal transportation development, and the results of the evaluation model can objectively reflect the level of multimodal transportation development and problems in each province (city). The research results further enrich the theoretical system of intermodal transportation development and provide a reference for the relevant management departments in formulating intermodal transportation plans and policies by putting forward pertinent suggestions in the field of management. In the future, the research direction should include the ecological environment, economic benefits, and other indicators into the evaluation system, expand the research scope of the modes of combined transportation such as public rail transport and public air transport, and improve the applicable scope of the evaluation model and the evaluation capability of specific scenarios. [ABSTRACT FROM AUTHOR]

As a sustainable transportation mode, high-speed railway (HSR) has been developing rapidly during the past decade in China. With the formation of dense HSR network, how to improve the utilization efficiency of train-sets (the carrying tools of HSR) has been a new research hotspot. Moreover, the emergence of railway transportation hubs has brought great challenges to the traditional train-sets' utilization mode. Thus, in this paper, we address the issue of train-sets' utilization problem with the consideration of railway transportation hubs, which consists of finding an optimal Train-set Circulation Plan (TCP) to complete trip tasks in a given Train Diagram (TD). An integer programming TCP model is established to optimize the train-set utilization scheme, aiming to obtain the one-to-one correspondence relationship among sets of train-sets, trip tasks, and maintenances. A genetic algorithm (GA) is designed to solve the model. A case study based on Nanjing and Shanghai HSR transportation hubs is made to demonstrate the practical significance of the proposed method. The results show that a more efficient TCP can be formulated by introducing train-sets being dispatched among different stations in the same hub. [ABSTRACT FROM AUTHOR]

Purpose. To survey the species diversity of home dust mites (HDM) in Xishuangbanna, a tropical rainforest region in Southwest China. Methods. From August 2010 to January 2011, mite-allergic patients and healthy controls were invited to participate. Dust samples from the patients’ homes were collected, and mites in the samples were isolated. Permanent slides were prepared for morphologically based species determination. Results. In total, 6316 mite specimens of morphologically identifiable species were found in 233 dust samples taken from 41 homes. The result shows that the mite family of Pyroglyphidae occupied the highest percentage of the total amount of mites collected, followed by Cheyletidae family. The most common adult Pyroglyphidae mites were Dermatophagoides (D.) farinae, D. pteronyssinus, and D. siboney. The most common mites found from other families were Blomia tropicalis, Tyrophagus putrescentiae, and Aleuroglyphus ovatus. Four main allergenic dust mite species D. farinae, D. pteronyssinus, D. siboney, and Blomia tropicalis were found to be coinhabiting in 6/41 homes. Conclusion. The HDM population in homes in Xishuangbanna, a tropical rainforest region in Southwest China, has its own characteristics. It has rich dust mite species and the dust mite densities do not show significant variation across seasons. [ABSTRACT FROM AUTHOR]

Background: Impaired bile acid (BA) metabolism has been associated with the progression of type 2 diabetes (T2D). However, the contribution of BAs to the pathogenesis of latent autoimmune diabetes in adults (LADA) remains unclear. This study was aimed at investigating the association of serum BAs with different diabetes types and analyzing its correlation with main clinical and laboratory parameters., Methods: Patients with LADA, patients with T2D, and healthy controls (HCs) were enrolled. Serum BA profiles and inflammatory cytokines were measured. The correlation of BA species with different indicators was assessed by Spearman's correlation method., Results: Patients with diabetes (LADA and T2D) had significantly higher serum BAs, especially conjugated BAs, compared with those in HCs. Nevertheless, serum BA profiles had no special role in the progression of LADA, because no significant differences in BAs were observed between LADA and T2D patients. Interestingly, HbA1c levels and HOMA- β were found to be correlated with a series of BA species. Proinflammatory cytokines (IL-1 β , IL-6, and TNF- α ) and anti-inflammatory cytokine (IL-10) were all positively associated with several BA species, especially the conjugated secondary BAs., Conclusion: Serum BAs regulate glucose homeostasis, but have no special value in the pathogenesis of LADA patients. Our study adds further information about the potential value of serum BAs in different types of diabetes., Competing Interests: The authors declare that they have no competing interests., (Copyright © 2022 Yu Zhou et al.)