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Aims: In this paper, we aim to present our designated digitization tool and interrogate its reliability and feasibility by comparing ST shift, ST area, T-amplitude, and QT interval measurements from three observers. Methods: Fifty ST elevation myocardial infarction electrocardiograms were digitized and analyzed offline by three investigators blindly via in-house developed software in MATLAB environment. Measurements were compared with analysis of variance and Friedman's test, and correlations were quantified via Pearson's and Spearman's tests. Results: Six electrocardiogram records were excluded prior to digitization due to inadequate quality. Mean ST shift (0.19±0.27, 0.21±0.27, 0.19±0.27 mV, p=409), ST area (0.0841±0.1069, 0.0885±0.0981, 0.0871±0.1113 mV sec, p=0.792), T-amplitude (0.59±0.42, 0.59±0.40, 0.57±0.38 mV, p=0.071), and QT interval measurements (0.35±0.07 sec, 0.36±0.06 sec, 0.36±0.05 sec, p=0.256) of three observers were not statistically different. All observer pairs showed significant and substantial correlations in all four parameters with correlation coefficients ranging between 0.803-0.974 (p<0.001 was for all correlations between each paired observer). Conclusion: Digitization of paper electrocardiogram records enables integral (area) analysis in paper records and more detailed analysis for researchers with paper electrocardiogram archives or lack of signal recording opportunity. Our designated publicly available tool can be reliably used in this process. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Legal Medicine / Adli Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Hand hygiene is one of the most effective infection control measures to prevent the spread of healthcare-associated infections (HCAI). Water, soap, paper towel and hand disinfectant must be available and adequate in terms of effective hand hygiene. The adequacy of hand hygiene products or keeping water-soap and paper towel is still a problem for many developing countries like Turkey. In this multicenter study, we analyzed the adequacy in number and availability of hand hygiene products. Materials and Methods: This study was performed in all intensive care units (ICUs) of 41 hospitals (27 tertiary-care educational, 10 state and four private hospitals) from 22 cities located in seven geographical regions of Turkey. We analyzed water, soap, paper towel and alcohol-based hand disinfectant adequacy on four different days, two of which were in summer during the vacation time (August, 27th and 31st 2016) and two in autumn (October, 12th and 15th 2016). Results: The total number of ICUs and intensive care beds in 41 participating centers were 214 and 2357, respectively. Overall, there was no soap in 3-11% of sinks and no paper towel in 10-18% of sinks while there was no alcohol-based hand disinfectant in 1-4.7% of hand disinfectant units on the observation days. When we compared the number of sinks with soap and/or paper towel on weekdays vs. weekends, there was no significant difference in summer. However, on autumn weekdays, the number of sinks with soap and paper towel was significantly lower on weekend days (p<0.0001, p<0.0001) while the number of hand disinfectant units with alcohol-based disinfectant was significantly higher (p<0.0001). Conclusion: There should be adequate and accessible hand hygiene materials for effective hand hygiene. In this study, we found that soap and paper towels were inadequate on the observation days in 3-11% and 10-18% of units, respectively. Attention should be paid on soap and paper towel supply at weekends as well. [ABSTRACT FROM AUTHOR]

Aim: The coronavirus disease-2019 (COVID-19) pandemic since its inception, has significantly impacted the academic activities of medical doctors. The decrease in physicians’ workload and the urge to share new knowledge about the new disorder caused medical doctors to write and publish academic papers rapidly. We investigated the effects of the pandemic on the academic publishing behavior of dermatologists in Turkey. Materials and Methods: The study was conducted through a PubMed search using the keywords “Dermatology Turkey". Search limits were set for 2017- 2019 for the pre-pandemic period and 2020-2022 for the post-pandemic era. Irrelevant articles were manually excluded. The publication year, type and subject of publication, whether the study was multicenter or multidisciplinary, and the journal were noted for each paper. Data obtained were analyzed using the IBM SPSS Statistics 25 package program. Results: The search revealed 986 and 1420 articles for the pre- and post-pandemic periods, respectively. The most published subjects were drugs and drug eruptions before the pandemic and COVID-19 after the pandemic. An increase in the ratio of “letters to editors” and in multicenter studies was noted in the post-pandemic era. The distribution among the journals of publication changed strikingly, and 35.8% of papers were published in only two journals after the pandemic. Conclusion: There were significant changes in the publishing behavior of Turkish dermatologists during the pandemic. We believe that this study is important as a demonstration of the academic behaviors of dermatologists and a guide for young dermatologists who wish to publish. [ABSTRACT FROM AUTHOR]

Objective: Urinary incontinence (UI) is defined as the involuntary leakage of urine. UI is a challenging geriatric syndrome and most of the patients use absorbent products or diapers to hold urine and protect their clothes. We aimed in this study to evaluate the relationship between the use of absorbent products and the presence of depressive symptoms in patients with UI. Materials and Methods: One-hundred and fifty-nine (159) community-dwelling older adults with UI who applied to our hospital outpatient clinic of geriatrics were included in the study. A comprehensive geriatric assessment was performed on the patients, and the risk of depression was evaluated with the Yesavage geriatric depression scale (GDS). Those with a GDS score of 5 and above were considered as presence of depressive symptoms. Results: Depressive symptoms were determined in 71 patients (44.6%). 91.2% of the patients were female, and the mean age was 73.6±6.4 years. The patients were divided into two groups according to the presence of depressive symptoms. The rate of use of absorbent products was 68.6% in the group with depressive symptoms and 45.9% in the group without depressive symptoms, and the difference was statistically significant (p<0.05). Use of absorbent products increases the risk of depression regardless of sex, living alone, multimorbidity, and severity and the type of incontinence (odds ratio: 2.65, 95% confidence interval: 1.27-5.57, p=0.010). Conclusion: The use of absorbent products in patients with UI is associated with the depressive symptoms. These patients should be screened for depression and evaluated for appropriate treatment options for incontinence and depression. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Namık Kemal Tıp Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medical Journal of Bakirkoy is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Legal Medicine / Adli Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The International Maritime Organization and the North Atlantic Treaty Organization are today, enforcing increasingly stringent rules for maritime safety and security on a national and international scale. The need for security in the Black Sea has increased, the degree of danger has risen, and the risk of loss of life and destruction of ships or other surface or submersible marine vehicles cannot be overlooked. Autonomous underwater vehicles (AUVs) have various civil applications (targeting economic, industrial, and commercial interests), but military applications have recently gained prominence (needs for information, surveillance, and inspection, for the identification and destruction of risk obstacles). Given the high risk of destruction during the operation, solutions are being sought to enable the rapid and cost-free construction of AUVs without compromising their performance and efficiency. The paper's novelty is provided by the mention of 3D printing technologies as a possible solution, taking into account the successes in other essential fields of science and technology. The contribution of the paper was related to the AUV's body extremities (bow and stern), and the following factors were considered: geometric design using computer-aided design methods; hydrodynamic analysis of forms using computational fluid dynamics methods; and prototype manufacturing using 3D printing. [ABSTRACT FROM AUTHOR]

Improper ballasting can lead to severe damage, potentially resulting in loss of life, vessel damage, and environmental disasters. This paper systematically assesses system failures in ballast pump operation related to human errors that contribute to operational risks. Considering this objective, we developed a hybrid approach that combines the Cognitive Reliability and Error Analysis Method (CREAM) with Hazard and Operability (HAZOP). Within this study's context, HAZOP analysis is harnessed to pinpoint the risks inherent in intricate ballast operations, a crucial component of maritime safety. By integrating CREAM analysis, a comprehensive understanding of the role of human factors in systematic failures and operational risks is achieved. The research emphasizes the critical role of cognitive activities, including monitoring, planning, diagnosing, and maintaining, in ensuring the safe and efficient operation of ballast pump systems. This study highlights the importance of cognitive functions such as observation, planning, interpretation, and execution in addressing these issues. The HAZOP analysis successfully identifies various potential deviations and failures within the system, providing insights into the complex nature of ballast operations and the significance of human factors. The analysis method effectively pinpoints vulnerabilities and weaknesses, underlining the necessity of meticulous planning and proper execution to mitigate identified failures. By not only delineating the fundamental causal factors behind ballast system failures and the potential consequences of these failures but also aiming to elevate safety control measures, this paper strives to mitigate prospective losses in critical shipboard operations. [ABSTRACT FROM AUTHOR]

Copyright of Bagcilar Medical Bulletin / Bağcılar Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

46,XX individuals born with severely masculinized genitals due to congenital adrenal hyperplasia (CAH) who have been assigned male at birth and reared male can successfully establish a male gender identity/role, find employment, marry, function sexually with a female partner, and develop positive mental health status. While there were a few individuals who reportedly did not fare well or who changed gender to female, the majority of those identifying as males appear to have an overall good quality of life. Parental/family support, along with the support of others, appears essential to a positive outcome as a male, or as a female. This paper suggests that serious consideration should be given to male gender assignment and rearing and, in certain situations, is justified. Disorders of sex differentiation teams should inform parents about the option for male assignment and rearing in 46,XX CAH infants with severe genital masculinization, which is a rare condition. To provide this option is concordant with the principles of ethics, transparency and with the Endocrine Society Guidelines and the American Academy of Pediatrics’ policy of fully informed consent. [ABSTRACT FROM AUTHOR]

Expeditious strides in the fields of biomaterials, computer-aided design, and manufacturing have catapulted clear aligner therapy (CAT) to become a comprehensive orthodontic treatment modality. The efficiency of achieving planned tooth movement with clear aligners is a significant consideration while setting up the final treatment goals, as well as calculating treatment times and costs based on the available evidence. Contemporary research outcomes confirm that one of the most commonly reported clinical concerns with CAT is the discrepancy between the prescribed outcome in the digital treatment plan and the clinically achieved outcome from a given series of aligners. Inaccurate prediction of tooth movements may not only lead to a prolonged duration of aligner treatment with an additional need for refinement strategies; but it may also cause other concerns, such as patient burnout and increased potential for relapse. The authors of this paper have elucidated some of the critical elements that may help address this discrepancy between digitally prescribed and clinical outcomes based on an evidence-based approach with regard to the predictability and accuracy of CAT. A strong diagnostic acumen, judicious case selection, solid biomechanical understanding of various types of orthodontic tooth movements, a research framework that keeps pace with technological and material developments and provides evidence-based knowledge of the limitations of CAT; and above all, the ability of the clinician to continually innovate as per different clinical scenarios, all contribute to attaining treatment predictability, efficacy, and efficiency with CAT. [ABSTRACT FROM AUTHOR]

Introduction: Residency training may lead to the development of depressive conditions with possible academic and professional consequences. We determined the levels of depression in resident medical doctors (RMDs) and assess the factors influencing depression. Methods: This prospective cross-sectional questionnaire study was conducted on RMDs working in tertiary research hospital in İstanbul. Participation in the study was voluntary. A questionnaire was distributed to the RMDs participating in the study, and the Beck Depression Inventory-II (BDI-II) was used to measure depression levels. This study was presented as a paper at the 5th Eurasian Congress on Emergency Medicine and 12th Turkish Emergency Medicine Congress, November 10-13, 2016 (Antalya, Turkey). Results: A total of 161 RMDs were included in the study (participation rate: 68.8%). Of the RMDs, 65 (40.4%) had depressive symptoms (BDI-II >13). An exploratory analysis of possible risk factors showed that working night shifts, length of residency, and department in which the resident worked were factors for the development of depressive symptoms. There was no association between BDI-II scores and age, gender, marital status, number of children, living alone, recent loss of a loved one, presence of chronic illness, diagnosis of depression, or use of antidepressant medication. Conclusion: There is a high prevalence of depressive symptoms among RMDs, especially night workers, who have less experience in their residency. Active assessment of these RMDs to evaluate their depressive symptoms is important. Preventive measures and educational programmes to improve working conditions need to be reviewed. [ABSTRACT FROM AUTHOR]

Due to the high cost of data acquisition in many specific fields, such as intelligent agriculture, the available data is insufficient for the typical deep learning paradigm to show its superior performance. As an important complement to deep learning, few-shot learning focuses on pattern recognition tasks under the constraint of limited data, which can be used to solve practical problems in many application fields with data scarcity. This survey summarizes the research status, main models and representative achievements of few-shot learning from four aspects: model fine-tuning, meta-learning, metric learning and data enhancement, and especially introduces the few-shot learning-driven typical applications in intelligent agriculture. Finally, the current challenges of few-shot learning and its development trends in intelligent agriculture are prospected. [ABSTRACT FROM AUTHOR]

The advent of taxane-based chemotherapy has revolutionized breast cancer care. This advance has helped improve the response to downstaging tumors that might otherwise be inoperable. It has also helped in rendering clinically (cN+) positive lymph nodes (LNs) pathologically negative (ypN0). The standard of care for cN+ patients included post-mastectomy radiotherapy (PMRT), regardless of the response to neoadjuvant chemotherapy. However, PMRT in patients with 1-3 positive LNs still lacks definitive guidelines. Numerous retrospective results have been inconclusive about the benefit of PMRT on survival in patients with 1-3 positive LNs. This pooled analysis attempts to reach a consensus. The PubMed database was searched through October 2023. The search yielded 27 papers, of which 11 satisfied the inclusion criteria. The locoregional recurrence-free survival (LRRFS), disease-free survival (DFS), and overall survival (OS) for each study were tabulated when given, and two groups were created, the PMRT and NO PMRT, respectively. The results were then pooled for analysis. The total number of patients was 8340, 4136 in the PMRT group, and 4204 in the NO PMRT group, respectively. The LRRFS, DFS, and OS were 96.9%, 82.1%, and 87.3% for the PMRT group and 93.2%, 79.6%, and 84.8% for the NO PMRT group, respectively. There was no statistical significance in LRRFS, DFS, or OS between the two groups (p = 0.61, p = 0.61, and p = 0.38, respectively). PMRT does not seem to confer survival benefits in patients with pN1 rendered ypN0 for stages T1-3. This pooled analysis's findings should be confirmed prospectively with a longer period of follow-up. [ABSTRACT FROM AUTHOR]

This paper proposes an optimal method designed for use in a real-life situation to deal with port route choice decisions for evaluating and aggregating the daily net profit for liner shipping services to assist shipping lines in making optimal decisions under risk in the choice of the optimal route with the highest average daily profit for container liner shipping under the following un-certain combination factors: Freight rate, shipment demand, and fuel oil price. A cumulative prospect theory approach considers the decision-maker's attitude to describe decision-making under uncertainty applicable for any number of consequences to calculate the daily net profit model for container vessels. The results are compared with benchmark methods such as expected utility theory. This paper includes an application of the proposed approach to Hai An container shipping lines in Vietnam in 2022. Furthermore, adaptive parameters are presented to improve a model's performance when data distribution varies over time or across different contexts. The results show that the larger the adaptive parameter, the higher the daily profit, but the growth rate diminishes. The findings suggest that the Hai Phong-Ho Chi Minh route emerges as the safest with the least effect and the lowest variation in cumulative prospect value of daily profit. The Hai Phong (HP)-Tan Cang Cai Mep (TCIT)- Ho Chi Minh (HCM)-Hai Phong route is recommended as the most effective and economically favorable strategy for managers seeking the highest cumulative daily profit. This paper not only explains that the actual calculated results align with decision makers' behavior, such as risk aversion, decision makers who prioritize stability are inclined to choose options or strategies that offer a higher level of certainty, even if it means foregoing higher profits, but also provides a practical and easy-to-apply method for choosing a shipping network. [ABSTRACT FROM AUTHOR]

Background: Non-invasive, rapid, and precise assessment of injury in the military settings is extremely important, yet difficult. Focused assessment with sonography in trauma (FAST) is being increasingly employed for assessing the location and severity of injury and guiding further treatment strategy. However, the evidence regarding the utility of FAST in the military settings is scattered. Aims: To evaluate the diagnostic performance of FAST in the assessment of injury in the military settings. Study Design: Meta-analysis. Methods: We identified all relevant papers via the PubMed, EMBASE, and Cochrane Library databases. We evaluated the quality of included studies by the Quality Assessment of Diagnostic Accuracy Studies-2 tool. We pooled the area under the curve (AUC), sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio as the effect sizes, followed by evaluating the heterogeneity among the studies by p value and I². Results: Among the 39 papers, a total of six papers were included. The sample size ranged from 15 to 396. The AUC of FAST for assessing the injury was 0.85. The pooled sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio were 0.66, 0.98, 33.1, 0.34, and 97, respectively. The heterogeneity among the studies was statistically significant (p=0.006, I²=78%). Conclusion: FAST is potentially valuable for assessing injury in the military settings. Due to its high specificity, FAST may be appropriate to rule in significant injury. However, because of its poor sensitivity, the ability of FAST to rule out injury cannot be relied upon. [ABSTRACT FROM AUTHOR]

PURPOSE Portal hypertension (PHT) and its sequelae are the most clinically important manifestations in cystic fibrosis-related liver disease (CFLD). This paper aimed to evaluate the safety and efficacy of a pre-emptive transjugular intrahepatic portosystemic shunt (TIPS) to prevent PHT-related complications in pediatric patients with CFLD. METHODS This was a prospective single-arm study on pediatric patients with CFLD, signs of PHT, and preserved liver function who underwent a pre-emptive TIPS in a single tertiary CF center between 2007 and 2012. The long-term safety and clinical efficacy were assessed. RESULTS A pre-emptive TIPS was performed on seven patients with a mean age of 9.2 years (± standard deviation: 2.2). The procedure was technically successful in all patients, with an estimated median primary patency of 10.7 years [interquartile range (IQR) 0.5-10.7)]. No variceal bleeding was observed during the median follow-up of 9 years (IQR 8.1-12.9). In two patients with advanced PHT and rapidly progressive liver disease, severe thrombocytopenia could not be stopped. Subsequent liver transplantation revealed biliary cirrhosis in both patients. In the remaining patients with early PHT and milder porto-sinusoidal vascular disease, symptomatic hypersplenism did not occur, and liver function remained stable until the end of the follow-up. Inclusion for pre-emptive TIPS was discontinued in 2013 following an episode of severe hepatic encephalopathy. CONCLUSION TIPS is a feasible treatment with encouraging long-term primary patency to avoid variceal bleeding in selected patients with CF and PHT. However, as the progression of liver fibrosis, thrombocytopenia, and splenomegaly is inevitable, the clinical benefits due to pre-emptive placement appear to be minor. [ABSTRACT FROM AUTHOR]

This review explores the potential link between maternal obesity [body mass index (BMI) >30 during pregnancy] and the development of attention-deficit/hyperactivity disorder (ADHD) in offspring. This study assesses the strength of this association by examining epidemiological studies and investigating possible biological mechanisms, including inflammation, oxidative stress, hormonal changes, prenatal programing, and epigenetic modifications. In addition, the review considers moderating variables and discusses the public health implications, with the objective of providing valuable insights into addressing this complex relationship for future clinical approaches and public health policies. This original review conducted a comprehensive literature search in August 2023 using various databases and keywords related to maternal obesity and ADHD. English articles published from 2005 to 2023, including case-control studies, cross-sectional studies, cohort studies, and reviews were considered. Multiple authors independently conducted searches, screened titles/abstracts, and extracted data to ensure rigorous methodology. Initially, 414 articles were retrieved from various databases and managed using Zotero. After eliminating 96 duplicates, 318 articles remained for screening on Rayyan. Of these, 47 papers met the eligibility criteria and underwent full-text review for inclusion in the study. Multiple studies suggest a positive correlation between maternal obesity and ADHD symptoms in children. Additionally, maternal obesity is associated with other neurodevelopmental disorders and behaviors in offspring, including heightened motor and anxiety behaviors. The complex relationship between maternal obesity and ADHD necessitates further investigation. Although existing research indicates associations, causality remains unconfirmed. Genome-wide association studies reveal shared genetic pathways, supported by rodent models. Human studies must address confounding factors. Promising interventions exist but require validation. Comprehensive research encompassing genetic, environmental, and metabolic factors is crucial for understanding the full impact of maternal obesity on neurodevelopmental outcomes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Pediatric Emergency & Intensive Care Medicine / Çocuk Acil ve Voğun Bakım Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim of this paper is to examine the most relevant competitive factors of a shipyard. The method conducted interviews and questionnaires with multiple agents related to the company and analyzed several institutional, business, and academic documents. The case of study considered was the manufacturing center of Navantia, S.A. in the Ferrol estuary (A Coruña, North-West of Spain). The results indicate that the five most important competitive factors are the government and political support, the production organization, the product technology, manpower, and skills and knowledge. Thus, these five competitive factors are critical to analyze the competitiveness of a shipyard with the characteristics of the one studied for new uses of the ocean, such as offshore wind, wave energy, or aquaculture. [ABSTRACT FROM AUTHOR]

This paper aims to show the scale effects of vertical maneuvering derivatives for an underwater vehicle using computational fluid dynamics (CFD). The model scale and full-scale benchmark DARPA suboff hull forms were used in numerical vertical planar motion mechanism simulations to achieve this aim. The heave forces, pitch moments, and Euler coefficients are calculated together with the linear vertical maneuvering derivatives by implementing the Fourier series expansion approach. The results show that the coupled added mass terms are significantly influenced by the scale effects, whereas the impact of scale effects on the decoupled added mass and coupled and decoupled damping terms is negligible. Considering that the effects of the coupled added mass on the vertical maneuvering characteristics are almost negligible, the vertical maneuvering of a submarine is slightly influenced by the scale effects. [ABSTRACT FROM AUTHOR]

The new navigation channel for large vessels entering the Hau River through the Kenh Tat and Quan Chanh Bo channels was announced in January 2016. The navigation channel route through Dinh An estuary in Soc Trang province to Can Tho port was not deeply concerned by the agency because of the sedimentation phenomenon, which was very serious and complicated. Only small vessels of 1,000-2,000 DWT can pass through the Dinh An estuary navigation channel, whereas large vessels pass through the Kenh Tat and Quan Chanh Bo channels. However, the new navigation channel entering the Hau River is also seriously sedimented, especially in the Cua Dai An area, where the tributary route starts from the Hau River through the Quan Chanh Bo channel and the estuary area in the Duyen Hai harbor basin. These are two important bottlenecks that drastically reduce the throughput capacity of this new navigation channel. This paper proposed five options for the spatial arrangement of works to stabilize and protect the channel through the Dinh An estuary. A MIKE 21 couple mode was used to simulate hydrodynamic and sediment transport in the study area, and the impact of these options on the characteristics, including water level, flow velocity, and bottom topographic change, was analyzed and evaluated. Based on these results, an optimal solution was suggested. [ABSTRACT FROM AUTHOR]

The vital role of container liner shipping in international trade suggests that understanding why container liner firms go bankrupt is crucial to the sustainability of the maritime supply chain to improve resilience. Considering the insolvency of Hanjin Shipping as a case study, this paper investigates the probabilistic relationships among the bankruptcy causal factors that are disclosed qualitatively and quantitatively, exploiting a fuzzy Bayes network approach. A sensitivity analysis is conducted to increase the accuracy of the findings. Outcomes of the paper reveal that an integrated approach comprising of both endogenous and exogenous causal factors is a more powerful approach to explain the demise of Hanjin Shipping. Compared to exogenous factors, endogenous factors account more for the collapse of the firm. Furthermore, it is found that government support would have been a more influential measure to mitigate the negative effects of the demise compared to the merging and acquisition practice. Competitor liner operators, policymakers, and stakeholders in the maritime supply chain ecosystem can utilize the outcomes of this research to mitigate the bankruptcy risk and improve the maritime supply chain resilience capacity. [ABSTRACT FROM AUTHOR]

Botulinum toxin A (BTXA) is considered a pharmacological agent that may provide an alternative treatment to surgery in strabismus. It can be used as both a diagnostic and therapeutic agent in various concomitant, paralytic, and restrictive disorders. The major advantage of BTXA treatment is that it is non-invasive and does not impact the patient's chance for future surgery in case of an unfavorable response. In some selected disorders, BTXA has become the primary choice of treatment, whereas surgery is found to be more effective in others. Accumulated knowledge and experience have demonstrated that BTXA is more than merely an alternative treatment and has additional specific indications such as in unstable deviations and as an adjunct to surgery. Patients with recurrent deviations despite multiple surgeries are also good candidates for BTXA treatment. Although the major expectation is to obtain a permanent result, BTXA can also be used as a maintenance treatment. This paper mainly focuses on the current indications for the use of BTXA in strabismology, with special emphasis on ideal first-choice applications referred to as "golden indications," within the scope of the author's own experience with the use of BTXA over 30 years. [ABSTRACT FROM AUTHOR]

Enhanced recovery after cardiac surgery (ERACS) is a multi-disciplinary approach to improve patient outcomes and reduce complications following cardiac surgery. The aim of ERACS protocol is to optimize pre-operative preparation, reduce surgical trauma, and minimize postoperative stress.The protocol has been shown to improve patient outcomes, including shorter hospital stays, lower rates of complications, and faster return to normal activities. It is important to note that ERACS is a multi-disciplinary approach, and requires close collaboration between surgeons, anaesthesiologists, nurses, and other healthcare professionals to ensure successful implementation. Anaesthesiologists play a crucial role in the ERACS protocol, as they are responsible for the management of the patient's anaesthesia and pain management during and after surgery. In this paper provide an overview of the ERACS protocol from the perspective of an anaesthesiologist. [ABSTRACT FROM AUTHOR]

Copyright of Bezmialem Science is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of Legal Medicine / Adli Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Molecular Imaging & Radionuclide Therapy is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Molecular Imaging & Radionuclide Therapy is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Neurology / Turk Noroloji Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Pediatric Emergency & Intensive Care Medicine / Çocuk Acil ve Voğun Bakım Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This paper investigates the fatty acid profiles of fish oil extracted from by-products of cultured Black Sea salmon, Oncorhynchus mykiss, using conventional [conventional fish oil (CFO)] and dry freezing oil [dry freezer oil (DFO)] techniques. In the CFO and DFO groups, monounsaturated fatty acid + polyunsaturated fatty acid (PUFA) comprised 74.00% and 72.68% of the total fatty acids, respectively. The highest PUFA was linoleic acid (CFO=14.22%, DFO=13.15%) with Docosahexaenoic acid (DHA, C22:6n3) being the second most concentrated fatty acid for PUFA in the CFO (8.12%) and DFO (8.02%) groups, followed by eicosapentaenoic acid (EPA, C20:5n3) (CFO=4.39%, DFO=2.87%). Similarly, the difference between groups in omega-3 was statistically significant (p<0.05) and the CFO ratio was higher in the DFO. The PI, AI, TI, h/H, and UI percentages in the CFO group were 0.99, 0.37, 0.26, 2.98, and 1.73%, respectively, while in the DFO group they were 0.80, 0.35, 0.31, 2.83, and 1.61%, respectively. The findings of this study conclude that the oils obtained from Black Sea salmon by-products are rich in omega-3 fatty acids and have good lipid quality indexes. [ABSTRACT FROM AUTHOR]

Worldwide, breast cancer constitutes the most common malignant neoplasm among females, impacting 2.1 million women annually. Interventional oncology techniques have been recently added as an additional therapeutic and palliative alternative in breast cancer metastatic disease, concerning mainly osseous, liver, and lung metastasis. In the current literature, there are reports of promising results and documented efficacy regarding the ablation of liver and lung metastasis from breast carcinoma, transarterial embolization or radioembolization, as well as the treatment of osseous metastatic disease. These literature studies are limited by the heterogeneity of breast cancer disease, the evaluation of variable different parameters, as well as the retrospective nature in most of the cases. Consequently, dedicated prospective series and randomized studies are required to identify the role of minimally invasive local therapies of interventional oncology armamentarium. The present review paper focuses upon the current role of interventional oncology techniques for the curative or palliative treatment of metastatic breast cancer disease. The purpose of this review paper is to present the current minimally invasive procedures in the treatment of metastatic breast disease, including local control rates and survival rates. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Neurology / Turk Noroloji Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Research on the impact of inputs has a long history in the country; however, because of the dispersion and diversity in the results of various experiments, it is difficult to achieve a general conclusion. In this study, a meta-analysis approach has been used to overcome this problem in order to achieve a single result by integrating and re-analyzing the findings of independent experiments. For this purpose, scientific articles published by researchers of the country regarding the effect of salinity stress on cotton yield were investigated. Articles were selected so that, in their meta-analysis of data required to perform there. The data necessary for the implementation of the meta-analysis is present in them. The results of this study showed that from 1996 to 2017; 15 papers and thesis were published on the effects of salinity stress on yield, early maturing and number of bolls in upland cotton (Gossypiumhirsutum L.). With increasing salinity stress, yield and number of bolls decreased. The standardized values for salinity stress effect on cotton yield were significant in all five treatments (control via salinity, control via 2-3 dS m-1, control via 4-5 dS m-1, control via 6-7 dS m-1, control via 8- 9 dS m-1) compared to control (P<0.001). The standardized values of the effect of salt stress on cotton aging were significant in all five treatments compared to control. The standardized values of the effect of salt stress on cotton aging were significant in all five treatments compared to control. Results showed increasing salinity stress can cause early maturing in cotton. The standardized values for the effect of salinity stress on number of bolls per cotton plant, in the comparison of the total treatments of salinity stress, 2-3 dS m-1, 6-7 dS m-1 and 8-9 dS m-1 were significant compared to control (P<0.001). In general, the results of this study showed that salinity stress can reduce yield of cotton by reducing the number of bolls and also can cause early maturing on cotton. [ABSTRACT FROM AUTHOR]

This paper reviews translational research in psychiatry, focusing on those programs addressing the problem of the validity of psychiatric diagnoses. In medicine in general, and in psychiatry in particular, the term "translational" is used with different meanings. A conceptual analysis suggests that there are at least seven different types of translational research in psychiatry: T1 ("bench-to-bedside" development of tools and treatments), T2 (application of animal models to human psychiatry), T3 (papers focusing on the mind-brain gap, studying biological, neurobiological and cognitive dysfunctions), T4 (personalised therapies and prediction of treatment responses), T5 ("bedside-to-bench" translation of population data for laboratories), T6 (implementation of treatments at the population level, including accessibility and quality of services), and T7 (improving translational knowledge in residents' trainings and researchers' careers). Concerning the problem of validity of psychiatric diagnoses, new neurocognitive models like the Research Domain Criteria project are considered, in particular the translational program of cross-validation aimed at reducing the gap between neuroimaging data and psychopathological scores derived from rating-scales. It is shown that these programs are useful, filling some of the current research gaps, but it is also stressed that they carry implicit realist and reductionist assumptions. It is finally suggested that the formation of mental symptoms is a complex process involving both neurocognitive and semantic factors, which raises doubts about the possibility of complete translations, without residuals. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to identify the strategies used for the diagnosis and treatment of patients with temporomandibular disorders (TMDs) by general dental practitioners (GDPs) in the city of Istanbul. Methods: A total of 154 GDPs were assessed by a single examiner in this questionnaire-based study. Descriptive statistics were calculated for all variables, and the results were analyzed at a 95% CI and statistical power of 80% with the significance level set at P < .05. Results: The most frequently employed strategies for obtaining a diagnosis were patients' medical history (33.1%), physical examination (37.7%), and a combination of diagnostic methods (29.2%). The most commonly referred specialties were prosthodontics (62.2%) and maxillofacial surgery (36.9%). All GDPs treated their TMD patients with occlusal splints, and the majority of the occlusal splints were hard occlusal splints (62.8%). Half of the GDPs considered the etiology of TMD to involve stress, whereas 49.4% believed that TMD is of a multifactorial etiology. Conclusion: The GDPs clarified that TMD patients were mostly treated with occlusal splints and this datum is consistent with the suggestions of previous consensus papers. [ABSTRACT FROM AUTHOR]

Copyright of Hamidiye Medical Journal is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This paper showcases a data-driven non-linear adaptive controller design employing an unfalsification approach to attain optimal estimates for unknown parameters in an autonomous underwater vehicle (AUV). These estimates are applied to the controller to enable precise trajectory tracking. The controller design presented is capable of adapting to parametric changes and uncertainties while fulfilling the desired performance criteria using an effective parameter update method of unfalsification. The results were validated through simulations conducted using MATLAB/SIMULINK. [ABSTRACT FROM AUTHOR]

Calyceal diverticula are rare outpouchings of the upper collecting system that likely have a congenital origin. The incidence of the stone formation in the calyceal diverticula is up to 50%. The most effective diagnostic method is the computed tomography urogram. Treatment options for symptomatic patients include shock -wave lithotripsy, ureteroscopic or percutaneous methods, and laparoscopic surgery. The treatment option should be selected based on the basis of the diverticulum location and stone burden. This paper reports an interesting case of a 19-year-old boy with a stone burden of 1.663 mm3 in the calyceal diverticula of the right kidney. The patient underwent a robot-assisted procedure using the daVinci© Xi system. [ABSTRACT FROM AUTHOR]

Variants of the melanocortin-4 receptor (MC4R) gene are the most common cause of monogenic obesity. It has been shown that, while obesity cannot be controlled with diet and exercise, glucagon-like-peptide-1 receptor agonists (GLP-1 RA) provide weight loss in the short term. In this paper, our experience with liraglutide treatment in an adolescent patient carrying a MC4R gene variant is presented. A female patient was admitted first at the age of 12.5 years with a complaint of progressive weight gain. She had marked excess of appetite since infancy. On physical examination of the pubertal female patient with a body mass index (BMI) of 36.1 kg/m2 (3.48 standard deviation score), there was no pathological finding except diffuse acanthosis nigricans. Laboratory examinations revealed only insulin resistance. Weight loss was not achieved with lifestyle changes, metformin and orlistat treatments. On genetic examination, a sporadic heterozygous c.206T>G(p.I69R) variant that had been reported previously, was found in MC4R gene. Treatment with the GLP-1 RA, liraglutide, was initiated and a 19.2% reduction was achieved in the body weight and BMI at the end of 32 weeks. However, the patient, whose treatment compliance was disrupted due to significant gastrointestinal complaints, returned to her former weight within a few months (13 weeks) after treatment was stopped. In this case with a known pathogenic variant in MC4R gene, decrease of appetite and weight loss were achieved with liraglutide treatment, but side-effects of this treatment led to discontinuation of therapy. In such cases, there is need for effective and tolerable treatment options. [ABSTRACT FROM AUTHOR]

Adverse drug reactions (ADRs) are a prominent cause of morbidity and mortality and higher healthcare expenditures. Healthcare professionals (HCPs) play a crucial role in ADR reporting through spontaneous reporting systems, but under-reporting is their major limitation. The goal of this study is to evaluate HCPs' knowledge, attitude, and practice regarding ADR reporting as well as the factors that influence reporting using research papers that are currently available. A literature search was conducted using sources such as PubMed, Scopus, and Google Scholar to find studies that evaluated HCPs' knowledge, attitudes, and practices regarding ADRs reporting in Ethiopia. A standard procedure of systematic review protocol was used to conduct this review. Demographic factors, sample size, response rate, survey delivery, HCP working setting, and encouraging and discouraging factors of ADR reporting were extracted from articles. A total of 17 articles were included in the systematic review out of 384. The number of HCPs in the included studies ranged from 62 to 708. Response rate ranges from 76.1% to 100%. Most of the research included in this evaluation looked at HCPs, who worked in hospitals. When pharmacists were compared to other HCPs, they were more likely to report ADRs; because they had higher knowledge, attitude, and practice. Lack of understanding, unavailability of reporting forms, uncertainty about the causal relationship between the drug and ADR, and failure to report because the ADR was well known were among the common hurdles to ADR reporting identified in research. To improve reporting, educational initiatives and continued training in pharmacovigilance and ADRs are frequently recommended considerations. In Ethiopia, there is a pressing need to close the gap in HCP knowledge, attitudes, and practice regarding PV and ADR reporting. To address this point, specific educational interventions based on existing gaps in ADR reporting should be developed and integrated into the health education curriculum or provided as in-service training after graduation. [ABSTRACT FROM AUTHOR]

Testicular adrenal rest tumors (TARTs) are benign tumors often bilaterally located and are mostly diagnosed in adulthood. TARTs are seen in approximately 94% of patients with congenital adrenal hyperplasia (CAH). In this paper, we present a case of TARTs and CAH detected on 18F-fluorodeoxyglucose (FDG) PET/CT, as a rare case described in only one report in the literature. A 42-year-old patient presented to our outpatient clinic due to testicular masses. The patient had azoospermia, and his ultrasound images revealed bilateral solitary masses. In 18F-FDG PET/CT, high activity uptake was observed in both testicles, and bilateral adrenal hyperplasia was detected incidentally. When the patient's anamnesis was questioned, it was determined that pubarche occurred at the age of nine years, his body weight was 82 kg, and his height was 153 cm. Because of the hormonal evaluation, the patient was diagnosed with CAH and TARTs. In conclusion, 18F-FDG PET/CT may play a decisive role in the evaluation of infertile men with testicular masses. [ABSTRACT FROM AUTHOR]

Sleep-related hypermotor epilepsy (SHE) should be differentiated from NREM parasomnias in terms of a similar clinical presentation. The lack of ictal and/or interictal epileptic encephalographic (EEG) features in SHE complicates the differential diagnosis. Moreover, epileptic paroxysmal arousal (PA) does not present with associated hyperkinetic motor events typical of SHE, and this should be carefully evaluated from confusional arousal (CA), a type of NREM parasomnia. In this term, this paper aims to present three patients referred to the Sleep and Disorders Unit with the prediagnosis of CA but diagnosed as epileptic PA following video-polysomnography (PSG) with multichannel EEG recordings; and aims to discuss the clinical, EEG, and PSG characteristics of these patients on the basis of literature data. [ABSTRACT FROM AUTHOR]

This study aimed to assess the safety of complex inferior vena cava (IVC) filter retrieval techniques through a systematic review of published literature. Using PubMed, a systematic review was conducted in line with the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines to identify articles published through April 2020 that reported on complex IVC filter retrieval techniques in >5 patients. Case reports, review papers, and studies that did not report on primary outcomes or variables of interest were excluded. Risk of bias was assessed using a modified Newcastle-Ottawa Quality Assessment scale. Pooled success and complication rates were calculated for the overall number of complex retrieval attempts as well as for each filter type and each complex retrieval method. Sixteen fair-quality and three good-quality studies met the inclusion criteria, with 758 patients (428 female) who had undergone 770 advanced retrieval attempts. The mean age of the patients was 46.5 ± 7.1 years (range: 14.1-90), and the mean dwell time was 602.5 ± 388.6 days (range: 5-7336). Regarding filters, 92.6% (702/758) were retrievable and 7.4% (56/758) were permanent. Indications for complex retrieval included the failure of standard retrieval (89.2%; 676/758) and tilting or embedding in the caval wall (53.8%; 408/758); 92.6% (713/770) of the advanced retrieval attempts were successful. The pooled success rate was 92.0% (602/654) for retrievable filters and 96.4% (53/55) for permanent filters (P = 0.422). Only 2.8% (21/758) of patients experienced major complications, and the major complication rate was not significantly associated with filter type (P = 0.183). Advanced techniques for IVC filter retrieval appear safe for the retrieval of retrievable filters and certain permanent filters, with a low short-term major complication rate. Further studies on complex retrieval techniques used to remove permanent filters should be conducted to clarify their safety with respect to filter type. [ABSTRACT FROM AUTHOR]

Background: Health records changed over time in the countries, and also Türkiye passed from paper versions to personal health records (PHR) and put patients at the center of the system by allowing them to become the master of their health data. Aims: Presenting the current state of the e-Nabız application nationwide in Turkey, and to evaluate the benefits of patients' online access to electronic health records and the system's interoperability. Study Design: A descriptive observational study Methods: In the Turkish PHR system (e-Nabız), services to patients to manage their health are categorized and analyzed within the scope of national digital health services. In addition, the data validation in the e-Nabız within itself has been systematically expressed. Results: The Turkish PHR system allows users to use 30 different services for treatment, prevention, health promotion, and healthrelated and interrelated areas. Moreover, some statistics regarding the categories specified in the e-Nabız system are included. Today, data is flowing from 28,608 system-integrated health facilities and 39 e-Nabız integrated public institutions. In addition, 4.5 billion transactions are done by people by 2023 and 220 million users are queried by physicians to reach patients' labs and results. Plus, the e-Nabız is adopted by 82% of the Türkiye population. Conclusion: There is no universal model for the content of the PHR. Given its importance to the patient, the content evolved and will continue to grow over the years. With the advent of coronavirus disease 2019, the system is equipped with three new services. The importance of these services over time and in the future has been demonstrated with increasing momentum. [ABSTRACT FROM AUTHOR]