1. Ironing out the phosphorus problem.
- Author
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Zaritsky, Joshua J. and Salusky, Isidro B.
- Subjects
- *
PHOSPHORUS in the body , *CLINICAL trials , *CHRONIC kidney failure , *HYPOCALCEMIA , *BLOOD plasma , *KIDNEY diseases , *DIALYSIS (Chemistry) - Abstract
Control of serum phosphorus remains a vexing problem in chronic kidney disease. Although novel dialysis regimens may provide excellent phosphorus control, phosphate binders remain necessary for most dialysis patients. Block et al. present a phase I clinical trial examining the safety and efficacy of SBR759, a novel non-calcium, iron-based phosphate binder. Although the risks of iron accumulation and hypocalcemia must be addressed, this phosphate binder appears to be well tolerated and effective and offers a powder-based formulation. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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