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Your search keyword '"Falony, Gwen"' showing total 11 results
Start Over Author "Falony, Gwen" Publication Year Range Last 50 years Publisher bmj publishing group
11 results on '"Falony, Gwen"'

2. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic upplementation on improved metabolism.

Author

Belda, Eugeni, Voland, Lise, Tremaroli, Valentina, Falony, Gwen, Adriouch, Solia, Assmann, Karen E., Prifti, Edi, Aron-Wisnewsky, Judith, Debédat, Jean, Le Roy, Tiphaine, Nielsen, Trine, Amouyal, Chloé, André, Sébastien, Andreelli, Fabrizio, Blüher, Matthias, Chakaroun, Rima, Chilloux, Julien, Pedro Coelho, Luis, Carlota Dao, Maria, and Das, Promi

Subjects
SHOTGUN sequencing, GASTRIC banding, MICROBIAL metabolism, BIOTIN, MORBID obesity, ADIPOSE tissue diseases
Published
2022
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3. Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice.

Author

Le Roy, Tiphaine, Moens de Hase, Emilie, Van Hul, Matthias, Paquot, Adrien, Pelicaen, Rudy, Régnier, Marion, Depommier, Clara, Druart, Céline, Everard, Amandine, Maiter, Dominique, Delzenne, Nathalie M., Bindels, Laure B., de Barsy, Marie, Loumaye, Audrey, Hermans, Michel P., Thissen, Jean-Paul, Vieira-Silva, Sara, Falony, Gwen, Raes, Jeroen, and Muccioli, Giulio G.

Subjects
METABOLIC disorders, KNOCKOUT mice, ENTEROBACTER cloacae, SHORT-chain fatty acids, FATTY acid-binding proteins, MICE
Published
2022
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4. Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health.

Author

Brial, François, Chilloux, Julien, Nielsen, Trine, Vieira-Silva, Sara, Falony, Gwen, Andrikopoulos, Petros, Olanipekun, Michael, Hoyles, Lesley, Djouadi, Fatima, Neves, Ana L., Rodriguez-Martinez, Andrea, Mouawad, Ghiwa Ishac, Pons, Nicolas, Forslund, Sofia, Le-chatelier, Emmanuelle, Le Lay, Aurélie, Nicholson, Jeremy, Hansen, Torben, Hyötyläinen, Tuulia, and Clément, Karine

Subjects
SHOTGUN sequencing, LOW-fat diet, TYPE 2 diabetes, BOTANY, BIOTIC communities, COMPUTATIONAL biology, MEDICAL sciences, LOCUS (Genetics)
Published
2021
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5. Gut microbiota dynamics and uraemic toxins: one size does not fit all.

Author

Joossens, Marie, Faust, Karoline, Gryp, Tessa, Anh Thi Loan Nguyen, Jun Wang, Eloot, Sunny, Schepers, Eva, Dhondt, Annemieke, Pletinck, Anneleen, Vieira-Silva, Sara, Falony, Gwen, Vaneechoutte, Mario, Vanholder, Raymond, Van Biesen, Wim, Huys, Geert Roger Bertrand, Raes, Jeroen, and Glorieux, Griet

Subjects
GUT microbiome, TOXINS
Published
2019
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8. Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD.

Author

Sabino, João, Vieira-Silva, Sara, Machiels, Kathleen, Joossens, Marie, Falony, Gwen, Ballet, Vera, Ferrante, Marc, Van Assche, Gert, Van der Merwe, Schalk, Vermeire, Severine, and Raes, Jeroen

Subjects
GUT microbiome, CHOLANGITIS, INFLAMMATORY bowel diseases, INFLAMMATORY bowel disease treatment, NUCLEOTIDE sequencing, METRONIDAZOLE, DIAGNOSIS, GENETICS, THERAPEUTICS
Published
2016
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9. Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates.

Author

Vandeputte, Doris, Falony, Gwen, Vieira-Silva, Sara, Tito, Raul Y., Joossens, Marie, and Raes, Jeroen

Subjects
*GUT microbiome, *ENTEROTYPES, *FECAL analysis, *BACTERIAL growth, *METAGENOMICS
Abstract

Objective: The assessment of potentially confounding factors affecting colon microbiota composition is essential to the identification of robust microbiome based disease markers. Here, we investigate the link between gut microbiota variation and stool consistency using Bristol Stool Scale classification, which reflects faecal water content and activity, and is considered a proxy for intestinal colon transit time. Design: Through 16S rDNA Illumina profiling of faecal samples of 53 healthy women, we evaluated associations between microbiome richness, Bacteroidetes:Firmicutes ratio, enterotypes, and genus abundance with self-reported, Bristol Stool Scale-based stool consistency. Each sample's microbiota growth potential was calculated to test whether transit time acts as a selective force on gut bacterial growth rates. Results: Stool consistency strongly correlates with all known major microbiome markers. It is negatively correlated with species richness, positively associated to the Bacteroidetes:Firmicutes ratio, and linked to Akkermansia and Methanobrevibacter abundance. Enterotypes are distinctly distributed over the BSS-scores. Based on the correlations between microbiota growth potential and stool consistency scores within both enterotypes, we hypothesise that accelerated transit contributes to colon ecosystem differentiation. While shorter transit times can be linked to increased abundance of fast growing species in Ruminococcaceae- Bacteroides samples, hinting to a washout avoidance strategy of faster replication, this trend is absent in Prevotella-enterotyped individuals. Within this enterotype adherence to host tissue therefore appears to be a more likely bacterial strategy to cope with washout. Conclusions: The strength of the associations between stool consistency and species richness, enterotypes and community composition emphasises the crucial importance of stool consistency assessment in gut metagenome-wide association studies. [ABSTRACT FROM AUTHOR]

Published
2016
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