Search

Your search keyword '"Yanan Wang"' showing total 1 results
Start Over Author "Yanan Wang" Topic amidation Publication Year Range Last 50 years Publisher american chemical society

Refine your results

1 results on '"Yanan Wang"'

1. Transition-Metal-Free Dehydrosilylative Difluoroamidationof Tetrahydroisoquinolines under Mild Conditions.

Author

Qiao Chen, Jiawei Zhou, Yanan Wang, Chao Wang, Xihong Liu, Zhaoqing Xu, Li Lin, and Rui Wang

Subjects
*TRANSITION metals, *TETRAHYDROISOQUINOLINES, *HYDROSILYLATION, *AMIDATION, *ACETAMIDE, *SUBSTITUTION reactions
Abstract

Disclosedherein is a dehydrosilylative difluoroamidation of α-Csp3–H of tetrahydroisoquinolines with α,α-difluoro-α-TMS-acetamides.The process, which occurs at ambient temperature in the absence ofany transition metals, provides direct access to a broad range ofα,α-difluoroacetamide-substituted tertiary amine derivativesin high yields. Moreover, the method was successfully applied in theCsp3–H-directed difluorophosphorylation and difluorocarboxylationunder the same conditions. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results