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Your search keyword '"Sétif, Pierre"' showing total 2 results
Start Over Author "Sétif, Pierre" Publication Year Range Last 50 years Publisher american association for the advancement of science
2 results on '"Sétif, Pierre"'

1. Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer

Author

Schuller, Jan M., Birrell, James, Tanaka, Hideaki, Konuma, Tsuyoshi, Wulfhorst, Hannes, Cox, Nicholas, Schuller, Sandra K., Thiemann, Jacqueline, Lubitz, Wolfgang, Sétif, Pierre, Ikegami, Takahisa, Schuller, Jan M., Birrell, James, Tanaka, Hideaki, Konuma, Tsuyoshi, Wulfhorst, Hannes, Cox, Nicholas, Schuller, Sandra K., Thiemann, Jacqueline, Lubitz, Wolfgang, Sétif, Pierre, and Ikegami, Takahisa

Abstract

Photosynthetic complex I enables cyclic electron flow around photosystem I, a regulatory mechanism for photosynthetic energy conversion. We report a 3.3-angstrom-resolution cryo–electron microscopy structure of photosynthetic complex I from the cyanobacterium Thermosynechococcus elongatus. The model reveals structural adaptations that facilitate binding and electron transfer from the photosynthetic electron carrier ferredoxin. By mimicking cyclic electron flow with isolated components in vitro, we demonstrate that ferredoxin directly mediates electron transfer between photosystem I and complex I, instead of using intermediates such as NADPH (the reduced form of nicotinamide adenine dinucleotide phosphate). A large rate constant for association of ferredoxin to complex I indicates efficient recognition, with the protein subunit NdhS being the key component in this process.

Published
2019

2. Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer.

Author

Schuller JM, Birrell JA, Tanaka H, Konuma T, Wulfhorst H, Cox N, Schuller SK, Thiemann J, Lubitz W, Sétif P, Ikegami T, Engel BD, Kurisu G, and Nowaczyk MM

Subjects
Cryoelectron Microscopy, Electron Transport, Models, Molecular, Protein Structure, Quaternary, Cyanobacteria physiology, Electron Transport Complex I physiology, Ferredoxins physiology, Photosynthesis, Photosystem I Protein Complex physiology
Abstract

Photosynthetic complex I enables cyclic electron flow around photosystem I, a regulatory mechanism for photosynthetic energy conversion. We report a 3.3-angstrom-resolution cryo-electron microscopy structure of photosynthetic complex I from the cyanobacterium Thermosynechococcus elongatus. The model reveals structural adaptations that facilitate binding and electron transfer from the photosynthetic electron carrier ferredoxin. By mimicking cyclic electron flow with isolated components in vitro, we demonstrate that ferredoxin directly mediates electron transfer between photosystem I and complex I, instead of using intermediates such as NADPH (the reduced form of nicotinamide adenine dinucleotide phosphate). A large rate constant for association of ferredoxin to complex I indicates efficient recognition, with the protein subunit NdhS being the key component in this process., (Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.)

Published
2019
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