42 results on '"Zorcolo, Luigi"'
Search Results
2. Right Colectomy with Intracorporeal Anastomosis: A European Multicenter Propensity Score Matching Retrospective Study of Robotic Versus Laparoscopic Procedures
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de’Angelis, Nicola, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Winter, Des C., Carcoforo, Paolo, Celentano, Valerio, Coccolini, Federico, Di Saverio, Salomone, Frontali, Alice, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, Petri, Roberto, Scabini, Stefano, Tonini, Valeria, Valverde, Alain, Zorcolo, Luigi, Bianchi, Giorgio, Ris, Frederic, and Espin, Eloy
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- 2023
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3. The pan - COVID - AGICT study. The impact of COVID-19 pandemic on surgically treated pancreatic cancer patients. A multicentric Italian study
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Giuliani, Giuseppe, Guerra, Francesco, Santelli, Francesco, Esposito, Alessandro, De Pastena, Matteo, Cova, Chiara, Bianchi, Beatrice, Nobile, Sara, Maruccio, Martina, Faustini, Federico, Turri, Giulia, Pedrazzani, Corrado, Kauffmann, Emanuele Federico, Boggi, Ugo, Solaini, Leonardo, Ercolani, Giorgio, Mastrangelo, Laura, Jovine, Elio, Di Franco, Gregorio, Morelli, Luca, Mazzola, Michele, Ferrari, Giovanni, Langella, Serena, Ferrero, Alessandro, La Mendola, Roberta, Hilal, Mohamnad Abu, Depalma, Norma, D'Ugo, Stefano, Spampinato, Marcello Giuseppe, Frisini, Marco, Brolese, Alberto, Palaia, Raffaele, Belli, Andrea, Cillara, Nicola, Deserra, Antonello, Cannavera, Alessandro, Sagnotta, Andrea, Mancini, Stefano, Pinotti, Enrico, Montuori, Mauro, Pecora, Irene, Messinese, Simona, Salvischiani, Lucia, Esposito, Sofia, Ferraro, Luca, Rega, Daniela, Delrio, Paolo, La Raja, Carlotta, Spinelli, Antonino, Massaron, Simonetta, De Nardi, Paola, Deidda, Simona, Restivo, Angelo, Marano, Alessandra, Borghi, Felice, Piccoli, Micaela, Cozzani, Federico, Del Rio, Paolo, Marcellinaro, Rosa, Carlini, Massimo, De Rosa, Raffaele, Scabini, Stefano, Maiello, Fabio, Polastri, Roberto, Zese, Monica, Parini, Dario, Casaril, Andrea, Moretto, Gianluigi, De Leo, Antonio, Catarci, Marco, Trapani, Renza, Zonta, Sandro, Marsanic, Patrizia, Muratore, Andrea, Coppola, Alessandro, Caputo, Damiano, Andreuccetti, Jacopo, Pignata, Giusto, Mariani, Lorenzo, Ceccarelli, Graziano, Giuseppe, Rocco, Bolzon, Stefano, Grasso, Mariateresa, Testa, Silvio, Germani, Paola, de Manzini, Nicolò, Coletta, Diego, De Franco, Lorenzo, Benigni, Roberto, Tribuzi, Angela, Marra, Ubaldo, Di Marino, Michele, Zorcolo, Luigi, Lisi, Giorgio, Allisiardi, Fabrizio, Grieco, Michele, Righetti, Carolina, Grassia, Michele, Lucchi, Andrea, Bagaglini, Giulia, Sica, Giuseppe S., Manara, Michele, Turati, Luca, Macone, Lorenzo, Carminati, Roberta, Mariani, Pierpaolo, Rizzo, Gianluca, Coco, Claudio, Pennella, Francesca Pennetti, Rondelli, Fabio, Romano, Lucia, Giuliani, Antonio, Albino, Vittorio, Leongito, Maddalena, David, Giulia, Misitano, Pasquale, Pasulo, Silvia, Baiocchi, Gian Luca, Baldari, Ludovica, Cassinotti, Elisa, Boni, Luigi, Capolupo, Gabriella Teresa, Caricato, Marco, Bombardini, Cristina, Anania, Gabriele, Dibra, Rigers, Martines, Gennaro, Oliva, Renato, Carati, Maria Vittoria, Grazi, Gian Luca, Marchegiani, Francesco, Spolverato, Gaya, Celotto, Francesco, Pucciarelli, Salvatore, La Torre, Filippo, Iannone, Immacolata, Krizzuk, Dimitri, Sammartino, Francesco, Catalano, Giorgia, Strignano, Paolo, Romagnoli, Renato, Piccione, Domenico, Nardo, Bruno, Reddavid, Rossella, Degiuli, Maurizio, Gerosa, Martino, Maggioni, Dario, Zuolo, Michele, Rigamonti, Marco, Ghazouani, Omar, Galleano, Raffaele, Percivale, Andrea, Tirloni, Luca, Moraldi, Luca, Fabbri, Nicolò, Feo, Carlo Vittorio, Colombo, Samuele, Merlini, Ilenia, Di Saverio, Salomone, Barbato, Giuseppe, Coratti, Francesco, Formisano, Giampaolo, Bianchi, Paolo Pietro, Bengala, Carmelo, Coratti, Andrea, Dorma, Maria Pia Federica, Abu Hilal, Mohamnad, and Di Benedetto, Fabrizio
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- 2024
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4. Correction to: Surgical treatment of colonic Crohn’s disease: a national snapshot study
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Celentano, Valerio, Pellino, Gianluca, Rottoli, Matteo, Poggioli, Gilberto, Sica, Giuseppe, Giglio, Mariano Cesare, Campanelli, Michela, Coco, Claudio, Rizzo, Gianluca, Sionne, Francesco, Colombo, Francesco, Sampietro, Gianluca, Lamperti, Giulia, Foschi, Diego, Ficari, Ferdinando, Vacca, Ludovica, Cricchio, Marta, Giudici, Francesco, Selvaggi, Lucio, Sciaudone, Guido, Peltrini, Roberto, Manfreda, Andrea, Bucci, Luigi, Galleano, Raffaele, Ghazouani, Omar, Zorcolo, Luigi, Deidda, Simona, Restivo, Angelo, Braini, Andrea, Di Candido, Francesca, Sacchi, Matteo, Carvello, Michele, Martorana, Stefania, Bordignon, Giovanni, Angriman, Imerio, Variola, Angela, Barugola, Giuliano, Di Ruscio, Mirko, Tanzanu, Marta, Geccherle, Andrea, Tropeano, Francesca Paola, Luglio, Gaetano, Sasia, Diego, Migliore, Marco, Giuffrida, Maria Carmela, Marrano, Enrico, Moretto, Gianluigi, Impellizzeri, Harmony, Gallo, Gaetano, Vescio, Giuseppina, Sammarco, Giuseppe, Terrosu, Giovanni, Calini, Giacomo, Bondurri, Andrea, Maffioli, Anna, Zaffaroni, Gloria, Resegotti, Andrea, Mistrangelo, Massimiliano, Allaix, Marco Ettore, Botti, Fiorenzo, Prati, Matteo, Boni, Luigi, Perotti, Serena, Mineccia, Michela, Giuliani, Antonio, Romano, Lucia, Graziano, Giorgio Maria Paolo, Pugliese, Luigi, Pietrabissa, Andrea, Delaini, GianGaetano, Spinelli, Antonino, and Selvaggi, Francesco
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- 2022
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5. The COVID - AGICT study: COVID–19 and advanced gastro-intestinal cancer surgical treatment. A multicentric Italian study on the SARS-CoV-2 pandemic impact on gastro-intestinal cancers surgical treatment during the 2020. Analysis of perioperative and short-term oncological outcomes
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Franco, Lorenzo De, Benigni, Roberto, Tribuzi, Angela, Marra, Ubaldo, Di Marino, Michele, Cova, Chiara, Bianchi, Beatrice, Nobile, Sara, Zorcolo, Luigi, Lisi, Giorgio, Allisiardi, Fabrizio, Grieco, Michele, Righetti, Carolina, Frisini, Marco, Brolese, Alberto, Grassia, Michele, Lucchi, Andrea, Bagaglini, Giulia, Sica, Giuseppe S., Manara, Michele, Turati, Luca, Macone, Lorenzo, Carminati, Roberta, Mariani, Pierpaolo, Rizzo, Gianluca, Coco, Claudio, Pennella, Francesca Pennetti, Rondelli, Fabio, Romano, Lucia, Giuliani, Antonio, Palaia, Raffaele, Belli, Andrea, Albino, Vittorio, Leongito, Maddalena, David, Giulia, Misitano, Pasquale, Pasulo, Silvia, Baiocchi, Gian Luca, La Mendola, Roberta, Hilal, Mohamnad Abu, Baldari, Ludovica, Cassinotti, Elisa, Boni, Luigi, Capolupo, Gabriella Teresa, Caricato, Marco, Pinotti, Enrico, Montuori, Mauro, Bombardini, Cristina, Anania, Gabriele, Dibra, Rigers, Martines, Gennaro, Solaini, Leonardo, Ercolani, Giorgio, Oliva, Renato, Carati, Maria Vittoria, Grazi, Gian Luca, Ghio, Giacomo, Marchegiani, Francesco, Pucciarelli, Salvatore, La Torre, Filippo, Iannone, Immacolata, Krizzuk, Dimitri, Sammartino, Francesco, Catalano, Giorgia, Strignano, Paolo, Romagnoli, Renato, Piccione, Domenico, Nardo, Bruno, Reddavid, Rossella, Degiuli, Maurizio, Gerosa, Martino, Maggioni, Dario, Zuolo, Michele, Rigamonti, Marco, Ghazouani, Omar, Galleano, Raffaele, Percivale, Andrea, Tirloni, Luca, Moraldi, Luca, Fabbri, Nicolò, Feo, Carlo Vittorio, Colombo, Samuele, Di Saverio, Salomone, Barbato, Giuseppe, Coratti, Francesco, Sagnotta, Andrea, Mancini, Stefano, Cillara, Nicola, Deserra, Antonello, Cannavera, Alessandro, Formisano, Giampaolo, Giuliani, Giuseppe, Guerra, Francesco, Messinese, Simona, Santelli, Francesco, Salvischiani, Lucia, Esposito, Sofia, Ferraro, Luca, Esposito, Alessandro, De Pastena, Matteo, Rega, Daniela, Delrio, Paolo, La Raja, Carlotta, Spinelli, Antonino, Massaron, Simonetta, De Nardi, Paola, Kauffmann, Emanuele Federico, Boggi, Ugo, Deidda, Simona, Restivo, Angelo, Marano, Alessandra, Borghi, Felice, Piccoli, Micaela, Depalma, Norma, D'Ugo, Stefano, Spampinato, Marcello, Cozzani, Federico, Del Rio, Paolo, Marcellinaro, Rosa, Carlini, Massimo, De Rosa, Raffaele, Scabini, Stefano, Maiello, Fabio, Polastri, Roberto, Turri, Giulia, Pedrazzani, Corrado, Zese, Monica, Parini, Dario, Casaril, Andrea, Moretto, Gianluigi, De Leo, Antonio, Catarci, Marco, Trapani, Renza, Zonta, Sandro, Marsanic, Patrizia, Muratore, Andrea, Di Franco, Gregorio, Morelli, Luca, Coppola, Alessandro, Caputo, Damiano, Andreuccetti, Jacopo, Pignata, Giusto, Mastrangelo, Laura, Jovine, Elio, Mazzola, Michele, Ferrari, Giovanni, Mariani, Lorenzo, Ceccarelli, Graziano, Giuseppe, Rocco, Bolzon, Stefano, Grasso, Mariateresa, Testa, Silvio, Germani, Paola, de Manzini, Nicolò, Langella, Serena, Ferrero, Alessandro, Coletta, Diego, Bianchi, Paolo Pietro, Bengala, Carmelo, and Coratti, Andrea
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- 2023
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6. COVID-19 free pathways decrease postoperative complications in patients undergoing elective colorectal surgery
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Deidda, Simona, Bao, Quoc Riccardo, Capelli, Giulia, Pucciarelli, Salvatore, Zorcolo, Luigi, Spolverato, Gaya, and Restivo, Angelo
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- 2022
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7. Clinical characteristics and outcomes in patients with early-onset locally advanced rectal cancer.
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Pretta, Andrea, Ziranu, Pina, Giampieri, Riccardo, Donisi, Clelia, Randon, Giovanni, Moledda, Giusy, Morano, Federica, Spanu, Dario, Cadoni, Andrea, Cimbro, Erika, Dell'Utri, Veronica, Rizzo, Daiana, Codipietro, Claudia, Semonella, Francesca, Puzzoni, Marco, Pusceddu, Valeria, Zorcolo, Luigi, Berardi, Rossana, Pietrantonio, Filippo, and Scartozzi, Mario
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- 2024
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8. Combined High—Throughput Proteomics and Random Forest Machine-Learning Approach Differentiates and Classifies Metabolic, Immune, Signaling and ECM Intra-Tumor Heterogeneity of Colorectal Cancer.
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Contini, Cristina, Manconi, Barbara, Olianas, Alessandra, Guadalupi, Giulia, Schirru, Alessandra, Zorcolo, Luigi, Castagnola, Massimo, Messana, Irene, Faa, Gavino, Diaz, Giacomo, and Cabras, Tiziana
- Subjects
AMINO acid synthesis ,IMMUNE checkpoint proteins ,METABOLIC reprogramming ,KREBS cycle ,RANDOM forest algorithms ,FIBRONECTINS - Abstract
Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity, including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra-tumor heterogeneity and its connections with metabolic reprogramming and epithelial–mesenchymal transition (EMT) were investigated with explorative shotgun proteomics complemented by a Random Forest (RF) machine-learning approach. Deep and superficial tumor regions and distant-site non-tumor samples from the same patients (n = 16) were analyzed. Among the 2009 proteins analyzed, 91 proteins, including 23 novel potential CRC hallmarks, showed significant quantitative changes. In addition, a 98.4% accurate classification of the three analyzed tissues was obtained by RF using a set of 21 proteins. Subunit E1 of 2-oxoglutarate dehydrogenase (OGDH-E1) was the best classifying factor for the superficial tumor region, while sorting nexin-18 and coatomer-beta protein (beta-COP), implicated in protein trafficking, classified the deep region. Down- and up-regulations of metabolic checkpoints involved different proteins in superficial and deep tumors. Analogously to immune checkpoints affecting the TME, cytoskeleton and extracellular matrix (ECM) dynamics were crucial for EMT. Galectin-3, basigin, S100A9, and fibronectin involved in TME–CRC–ECM crosstalk were found to be differently variated in both tumor regions. Different metabolic strategies appeared to be adopted by the two CRC regions to uncouple the Krebs cycle and cytosolic glucose metabolism, promote lipogenesis, promote amino acid synthesis, down-regulate bioenergetics in mitochondria, and up-regulate oxidative stress. Finally, correlations with the Dukes stage and budding supported the finding of novel potential CRC hallmarks and therapeutic targets. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue
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Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Restivo, Angelo, Cabras, Francesco, Deidda, Simona, Pretta, Andrea, Ziranu, Pina, Orrù, Sandra, Scartozzi, Mario, Zorcolo, Luigi, and Zavattari, Patrizia
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- 2022
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10. The Pan - COVID - AGICT Study. The impact of COVID-19 pandemic on surgically treated pancreatic cancer patients. A multicentric Italian study.
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Dorma, Maria Pia Federica, primary, Giuliani, Giuseppe, additional, Guerra, Francesco, additional, Santelli, Francesco, additional, Esposito, Alessandro, additional, De Pastena, Matteo, additional, Turri, Giulia, additional, Pedrazzani, Corrado, additional, Kauffmann, Emanuele Federico, additional, Boggi, Ugo, additional, Solaini, Leonardo, additional, Ercolani, Giorgio, additional, Mastrangelo, Laura, additional, Jovine, Elio, additional, Di Franco, Gregorio, additional, Morelli, Luca, additional, Mazzola, Michele, additional, Ferrari, Giovanni, additional, Langella, Serena, additional, Ferrero, Alessandro, additional, La Mendola, Roberta, additional, Abu Hilal, Mohamnad, additional, Depalma, Norma, additional, D’Ugo, Stefano, additional, Spampinato, Marcello Giuseppe, additional, Frisini, Marco, additional, Brolese, Alberto, additional, Palaia, Raffaele, additional, Belli, Andrea, additional, Cillara, Nicola, additional, Deserra, Antonello, additional, Cannavera, Alessandro, additional, Sagnotta, Andrea, additional, Mancini, Stefano, additional, Pinotti, Enrico, additional, Montuori, Mauro, additional, Coppola, Alessandro, additional, Di Benedetto, Fabrizio, additional, Coratti, Andrea, additional, Cova, Chiara, additional, Bianchi, Beatrice, additional, Nobile, Sara, additional, Maruccio, Martina, additional, Faustini, Federico, additional, Hilal, Mohamnad Abu, additional, Pecora, Irene, additional, Messinese, Simona, additional, Salvischiani, Lucia, additional, Esposito, Sofia, additional, Ferraro, Luca, additional, Rega, Daniela, additional, Delrio, Paolo, additional, La Raja, Carlotta, additional, Spinelli, Antonino, additional, Massaron, Simonetta, additional, De Nardi, Paola, additional, Deidda, Simona, additional, Restivo, Angelo, additional, Marano, Alessandra, additional, Borghi, Felice, additional, Piccoli, Micaela, additional, Cozzani, Federico, additional, Del Rio, Paolo, additional, Marcellinaro, Rosa, additional, Carlini, Massimo, additional, De Rosa, Raffaele, additional, Scabini, Stefano, additional, Maiello, Fabio, additional, Polastri, Roberto, additional, Zese, Monica, additional, Parini, Dario, additional, Casaril, Andrea, additional, Moretto, Gianluigi, additional, De Leo, Antonio, additional, Catarci, Marco, additional, Trapani, Renza, additional, Zonta, Sandro, additional, Marsanic, Patrizia, additional, Muratore, Andrea, additional, Caputo, Damiano, additional, Andreuccetti, Jacopo, additional, Pignata, Giusto, additional, Mariani, Lorenzo, additional, Ceccarelli, Graziano, additional, Giuseppe, Rocco, additional, Bolzon, Stefano, additional, Grasso, Mariateresa, additional, Testa, Silvio, additional, Germani, Paola, additional, de Manzini, Nicolò, additional, Coletta, Diego, additional, De Franco, Lorenzo, additional, Benigni, Roberto, additional, Tribuzi, Angela, additional, Marra, Ubaldo, additional, Di Marino, Michele, additional, Zorcolo, Luigi, additional, Lisi, Giorgio, additional, Allisiardi, Fabrizio, additional, Grieco, Michele, additional, Righetti, Carolina, additional, Grassia, Michele, additional, Lucchi, Andrea, additional, Bagaglini, Giulia, additional, Sica, Giuseppe S., additional, Manara, Michele, additional, Turati, Luca, additional, Macone, Lorenzo, additional, Carminati, Roberta, additional, Mariani, Pierpaolo, additional, Rizzo, Gianluca, additional, Coco, Claudio, additional, Pennella, Francesca Pennetti, additional, Rondelli, Fabio, additional, Romano, Lucia, additional, Giuliani, Antonio, additional, Albino, Vittorio, additional, Leongito, Maddalena, additional, David, Giulia, additional, Misitano, Pasquale, additional, Pasulo, Silvia, additional, Baiocchi, Gian Luca, additional, Baldari, Ludovica, additional, Cassinotti, Elisa, additional, Boni, Luigi, additional, Capolupo, Gabriella Teresa, additional, Caricato, Marco, additional, Bombardini, Cristina, additional, Anania, Gabriele, additional, Dibra, Rigers, additional, Martines, Gennaro, additional, Oliva, Renato, additional, Carati, Maria Vittoria, additional, Grazi, Gian Luca, additional, Marchegiani, Francesco, additional, Spolverato, Gaya, additional, Celotto, Francesco, additional, Pucciarelli, Salvatore, additional, La Torre, Filippo, additional, Iannone, Immacolata, additional, Krizzuk, Dimitri, additional, Sammartino, Francesco, additional, Catalano, Giorgia, additional, Strignano, Paolo, additional, Romagnoli, Renato, additional, Piccione, Domenico, additional, Nardo, Bruno, additional, Reddavid, Rossella, additional, Degiuli, Maurizio, additional, Gerosa, Martino, additional, Maggioni, Dario, additional, Zuolo, Michele, additional, Rigamonti, Marco, additional, Ghazouani, Omar, additional, Galleano, Raffaele, additional, Percivale, Andrea, additional, Tirloni, Luca, additional, Moraldi, Luca, additional, Fabbri, Nicolò, additional, Feo, Carlo Vittorio, additional, Colombo, Samuele, additional, Merlini, Ilenia, additional, Di Saverio, Salomone, additional, Barbato, Giuseppe, additional, Coratti, Francesco, additional, Formisano, Giampaolo, additional, Bianchi, Paolo Pietro, additional, and Bengala, Carmelo, additional
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- 2024
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11. Prediction of Response to Anti-Angiogenic Treatment for Advanced Colorectal Cancer Patients: From Biological Factors to Functional Imaging
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Corrias, Giuseppe, primary, Lai, Eleonora, additional, Ziranu, Pina, additional, Mariani, Stefano, additional, Donisi, Clelia, additional, Liscia, Nicole, additional, Saba, Giorgio, additional, Pretta, Andrea, additional, Persano, Mara, additional, Fanni, Daniela, additional, Spanu, Dario, additional, Balconi, Francesca, additional, Loi, Francesco, additional, Deidda, Simona, additional, Restivo, Angelo, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, Solinas, Cinzia, additional, Massa, Elena, additional, Madeddu, Clelia, additional, Gerosa, Clara, additional, Zorcolo, Luigi, additional, Faa, Gavino, additional, Saba, Luca, additional, and Scartozzi, Mario, additional
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- 2024
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12. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
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de’Angelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martínez-Pérez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolò, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi de’Angelis, Gian, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordoñez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
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- 2021
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13. Predictors of disease recurrence after curative surgery for stage I colon cancer - analysis of a nationwide retrospective study on behalf of the Italian Society of Surgical Oncology
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Pedrazzani, Corrado, Turri, Giulia, Braga, Marco, Delrio, Paolo, De Manzini, Nicolò, Zorcolo, Luigi, Spolverato, Gaya, Persiani, Roberto, De Luca, Raffaele, De Luca, Maurizio, Spinelli, Antonino, Montroni, Isacco, Altomare, Donato Francesco, Muratore, Andrea, Sica, Giuseppe, Nascimbeni, Riccardo, Anania, Gabriele, Coco, Claudio, Degiuli, Maurizio, and Verlato, Giuseppe
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- 2024
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14. Conversion to Open Surgery During Minimally Invasive Right Colectomy for Cancer: Results from a Large Multinational European Study
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Martínez-Pérez, Aleix, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Winter, Des C, Carcoforo, Paolo, Celentano, Valerio, Chiarugi, Massimo, Di Saverio, Salomone, Bianchi, Giorgio, Frontali, Alice, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, Petri, Roberto, Scabini, Stefano, Tonini, Valeria, Valverde, Alain, Zorcolo, Luigi, Ris, Frederic, Espin, Eloy, de'Angelis, Nicola, Carlo Schena, Francesca Pecchini, Lauren O'Connell, Filippo Aisoni, Alessia Urbani, Dario Tartaglia, Federico Coccolini, Francesco Arces, Christine Denet, Monica Ortenzi, Laura Vidal, Gianluca Pellino, Céphise Antonot, Jeanne Vertier, Ornella Perrotto, Giovanni Domenico De Palma, Antonio Santangelo, Raffaele De Rosa, Angelo Restivo, Simona Deidda, Lorenzo Orci, Sebastiano Bartoletti, Jean-Christophe Paquet, Enrico Andolfi, Martínez-Pérez, Aleix, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Winter, Des C, Carcoforo, Paolo, Celentano, Valerio, Chiarugi, Massimo, Di Saverio, Salomone, Bianchi, Giorgio, Frontali, Alice, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, Petri, Roberto, Scabini, Stefano, Tonini, Valeria, Valverde, Alain, Zorcolo, Luigi, Ris, Frederic, Espin, Eloy, de'Angelis, Nicola, Aleix, Martínez-Pérez, Micaela, Piccoli, Gianmaria, Casoni Pattacini, Des C, Winter, Paolo, Carcoforo, Valerio, Celentano, Massimo, Chiarugi, Salomone, Di Saverio, Giorgio, Bianchi, Alice, Frontali, David, Fuk, Pietro, Genova, Mario, Guerrieri, Miquel, Kraft, Zaher, Lakki, Bertrand, Le Roy, Renato, Micelli Lupinacci, Marco, Milone, Roberto, Petri, Stefano, Scabini, Valeria, Tonini, Alain, Valverde, Luigi, Zorcolo, Frederic, Ri, Eloy, Espin, Nicola, De'Angeli, Schena, Carlo, Pecchini, Francesca, O'Connell, Lauren, Aisoni, Filippo, Urbani, Alessia, Tartaglia, Dario, Coccolini, Federico, Arces, Francesco, Denet, Christine, Ortenzi, Monica, Vidal, Laura, Pellino, Gianluca, Antonot, Céphise, Vertier, Jeanne, Perrotto, Ornella, Domenico De Palma, Giovanni, Santangelo, Antonio, De Rosa, Raffaele, Restivo, Angelo, Deidda, Simona, Orci, Lorenzo, Bartoletti, Sebastiano, Paquet, Jean-Christophe, and Andolfi, Enrico
- Subjects
Minimally InvasivE surgery ,colon cancer ,right colectomy ,robotic surgery ,laparoscopy ,Surgery ,conversion - Abstract
Background: The risk of conversion to open surgery is inevitably present during any minimally invasive colorectal surgical procedure. Conversions have been associated with adverse postoperative and oncologic outcomes. No previous study has evaluated the specific causes and consequences of conversion during a minimally invasive right colectomy (MIS-RC). Materials and Methods: We analyzed the Minimally invasivE surgery for oncologic Right ColectomY (MERCY) study database including patients who underwent laparoscopic or robotic RC because of colon cancer between 2014 and 2020. Descriptive analyses were performed to determine the different reasons for conversion. Uni- and multivariate logistic regressions were run to identify potential variables associated with this outcome. Cox regression analyses were used to evaluate the impact of conversion on tumor recurrence. Results: Over a total of 1574 MIS-RC, 120 (7.6%) were converted to open surgery. The main reasons for conversion were procedural difficulties related to adherences from previous abdominal surgical procedures (39.2%), or owing to large tumor size or infiltration of adjacent structures (26.7%). Only 16.7% of the conversions were caused by intraoperative medical or surgical complications. Converted patients required longer operative times and developed more postoperative complications, both overall (39.2% versus 27.5%; P = .006) and severe ones (13.3% versus 8.3%; P = .061). Male gender (odds ratio [OR] = 1.89 [95% confidence interval: 1.31-2.71]), obesity (OR = 1.99 [1.4-2.83]), prior abdominal surgery (OR = 1.68 [1.19-2.37]), and pT4 cancers (OR = 4.04 [2.86-5.69]) were independently associated with conversion. Conversion to open surgery was not significantly associated with tumor recurrence (hazard ratios = 1.395 [0.724-2.687]). Conclusions: Although conversion to open surgery during MIS-RC for cancer is associated with worsened postoperative outcomes, it seems not to impact on the oncologic prognosis.
- Published
- 2023
15. Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy
- Author
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Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nicholas, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Boris, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Rigers, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, Celentano, Valerio, Institut Català de la Salut, [Rottoli M, Gori A, Pellino G] Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. [Pellino G] Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Flacco ME, Martellucci C] Department of Environmental and Preventive Sciences, University of Ferrara, Ferrara, Italy. [Spinelli A] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. Colorectal Surgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy, Vall d'Hebron Barcelona Hospital Campus, Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nichola, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Bori, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Riger, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, and Celentano, Valerio
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Adult ,Male ,Settore MED/18 - CHIRURGIA GENERALE ,Otros calificadores::/diagnóstico [Otros calificadores] ,Hospitals, Community ,colorectal cancer ,Community ,advanced stage ,COVID-19 (Malaltia) ,Cohort Studies ,Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [DISEASES] ,Retrospective Studie ,Other subheadings::/diagnosis [Other subheadings] ,virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES] ,Humans ,Pandemics ,Aged ,Retrospective Studies ,Pandemic ,SARS-CoV-2 ,COVID-19 ,Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES] ,General Medicine ,neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales [ENFERMEDADES] ,Hospitals ,Recte - Càncer - Diagnòstic ,Settore MED/18 ,Italy ,Còlon - Càncer - Diagnòstic ,Cohort Studie ,Colorectal Neoplasms ,Human - Abstract
ImportanceDelays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis.ObjectiveTo evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer.Design, Setting, and ParticipantsThis retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery.ExposuresAny type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections.Main Outcomes and MeasuresThe primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable.ResultsA total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95% CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95% CI, 1.15-1.53; P P = .03).Conclusions and RelevanceThis cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients.
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- 2022
16. The COVID - AGICT study: COVID–19 and advanced gastro-intestinal cancer surgical treatment. A multicentric Italian study on the SARS-CoV-2 pandemic impact on gastro-intestinal cancers surgical treatment during the 2020. Analysis of perioperative and short-term oncological outcomes
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Giuliani, Giuseppe, primary, Guerra, Francesco, additional, Messinese, Simona, additional, Santelli, Francesco, additional, Salvischiani, Lucia, additional, Esposito, Sofia, additional, Ferraro, Luca, additional, Esposito, Alessandro, additional, De Pastena, Matteo, additional, Rega, Daniela, additional, Delrio, Paolo, additional, La Raja, Carlotta, additional, Spinelli, Antonino, additional, Massaron, Simonetta, additional, De Nardi, Paola, additional, Kauffmann, Emanuele Federico, additional, Boggi, Ugo, additional, Deidda, Simona, additional, Restivo, Angelo, additional, Marano, Alessandra, additional, Borghi, Felice, additional, Piccoli, Micaela, additional, Depalma, Norma, additional, D'Ugo, Stefano, additional, Spampinato, Marcello, additional, Cozzani, Federico, additional, Del Rio, Paolo, additional, Marcellinaro, Rosa, additional, Carlini, Massimo, additional, De Rosa, Raffaele, additional, Scabini, Stefano, additional, Maiello, Fabio, additional, Polastri, Roberto, additional, Turri, Giulia, additional, Pedrazzani, Corrado, additional, Zese, Monica, additional, Parini, Dario, additional, Casaril, Andrea, additional, Moretto, Gianluigi, additional, De Leo, Antonio, additional, Catarci, Marco, additional, Trapani, Renza, additional, Zonta, Sandro, additional, Marsanic, Patrizia, additional, Muratore, Andrea, additional, Di Franco, Gregorio, additional, Morelli, Luca, additional, Coppola, Alessandro, additional, Caputo, Damiano, additional, Andreuccetti, Jacopo, additional, Pignata, Giusto, additional, Mastrangelo, Laura, additional, Jovine, Elio, additional, Mazzola, Michele, additional, Ferrari, Giovanni, additional, Mariani, Lorenzo, additional, Ceccarelli, Graziano, additional, Giuseppe, Rocco, additional, Bolzon, Stefano, additional, Grasso, Mariateresa, additional, Testa, Silvio, additional, Germani, Paola, additional, de Manzini, Nicolò, additional, Langella, Serena, additional, Ferrero, Alessandro, additional, Coletta, Diego, additional, Bianchi, Paolo Pietro, additional, Bengala, Carmelo, additional, Coratti, Andrea, additional, Franco, Lorenzo De, additional, Benigni, Roberto, additional, Tribuzi, Angela, additional, Marra, Ubaldo, additional, Di Marino, Michele, additional, Cova, Chiara, additional, Bianchi, Beatrice, additional, Nobile, Sara, additional, Zorcolo, Luigi, additional, Lisi, Giorgio, additional, Allisiardi, Fabrizio, additional, Grieco, Michele, additional, Righetti, Carolina, additional, Frisini, Marco, additional, Brolese, Alberto, additional, Grassia, Michele, additional, Lucchi, Andrea, additional, Bagaglini, Giulia, additional, Sica, Giuseppe S., additional, Manara, Michele, additional, Turati, Luca, additional, Macone, Lorenzo, additional, Carminati, Roberta, additional, Mariani, Pierpaolo, additional, Rizzo, Gianluca, additional, Coco, Claudio, additional, Pennella, Francesca Pennetti, additional, Rondelli, Fabio, additional, Romano, Lucia, additional, Giuliani, Antonio, additional, Palaia, Raffaele, additional, Belli, Andrea, additional, Albino, Vittorio, additional, Leongito, Maddalena, additional, David, Giulia, additional, Misitano, Pasquale, additional, Pasulo, Silvia, additional, Baiocchi, Gian Luca, additional, La Mendola, Roberta, additional, Hilal, Mohamnad Abu, additional, Baldari, Ludovica, additional, Cassinotti, Elisa, additional, Boni, Luigi, additional, Capolupo, Gabriella Teresa, additional, Caricato, Marco, additional, Pinotti, Enrico, additional, Montuori, Mauro, additional, Bombardini, Cristina, additional, Anania, Gabriele, additional, Dibra, Rigers, additional, Martines, Gennaro, additional, Solaini, Leonardo, additional, Ercolani, Giorgio, additional, Oliva, Renato, additional, Carati, Maria Vittoria, additional, Grazi, Gian Luca, additional, Ghio, Giacomo, additional, Marchegiani, Francesco, additional, Pucciarelli, Salvatore, additional, La Torre, Filippo, additional, Iannone, Immacolata, additional, Krizzuk, Dimitri, additional, Sammartino, Francesco, additional, Catalano, Giorgia, additional, Strignano, Paolo, additional, Romagnoli, Renato, additional, Piccione, Domenico, additional, Nardo, Bruno, additional, Reddavid, Rossella, additional, Degiuli, Maurizio, additional, Gerosa, Martino, additional, Maggioni, Dario, additional, Zuolo, Michele, additional, Rigamonti, Marco, additional, Ghazouani, Omar, additional, Galleano, Raffaele, additional, Percivale, Andrea, additional, Tirloni, Luca, additional, Moraldi, Luca, additional, Fabbri, Nicolò, additional, Feo, Carlo Vittorio, additional, Colombo, Samuele, additional, Di Saverio, Salomone, additional, Barbato, Giuseppe, additional, Coratti, Francesco, additional, Sagnotta, Andrea, additional, Mancini, Stefano, additional, and Formisano, Giampaolo, additional
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- 2023
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17. Supplementary Figure 3 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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18. Supplementary Figure Legends 1-7 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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19. Supplementary Figure 2 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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20. Supplementary Figure 5 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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21. Supplementary Figure 6 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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22. Supplementary Materials and Methods from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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23. Supplementary Figure 7 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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24. Supplementary Figure 1 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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25. Supplementary Figure 4 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
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Migliore, Cristina, primary, Martin, Valentina, primary, Leoni, Vera P., primary, Restivo, Angelo, primary, Atzori, Luigi, primary, Petrelli, Annalisa, primary, Isella, Claudio, primary, Zorcolo, Luigi, primary, Sarotto, Ivana, primary, Casula, Giuseppe, primary, Comoglio, Paolo M., primary, Columbano, Amedeo, primary, and Giordano, Silvia, primary
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- 2023
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26. The paradox of Zeno in bariatric surgery weight loss: Superobese patients run faster than morbidly obese patients, but can't overtake them
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Medas, Fabio, primary, Moroni, Enrico, additional, Deidda, Simona, additional, Zorcolo, Luigi, additional, Restivo, Angelo, additional, Canu, Gian Luigi, additional, Cappellacci, Federico, additional, Calò, Pietro Giorgio, additional, Pintus, Stefano, additional, and Fantola, Giovanni, additional
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- 2023
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27. Limits of Clinical Restaging in Detecting Responders After Neoadjuvant Therapies for Rectal Cancer
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Deidda, Simona, primary, Spolverato, Gaya, additional, Capelli, Giulia, additional, Bao, Riccardo Quoc, additional, Bettoni, Lorenzo, additional, Crimì, Filippo, additional, Zorcolo, Luigi, additional, Pucciarelli, Salvatore, additional, and Restivo, Angelo, additional
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- 2022
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28. The MIS-COVID-AGICT Study: Trend of Minimally Invasive Surgery for Gastrointestinal Cancer Treatment During the First Waves of the COVID-19 Pandemic in Italy. Subgroup Analysis from the COVID-AGICT Study: COVID-19 and Advanced Gastrointestinal Cancer Surgical Treatment
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Giuliani, Giuseppe, Coletta, Diego, Guerra, Francesco, Esposito, Sofia, Esposito, Alessandro, De Pastena, Matteo, Rega, Daniela, Delrio, Paolo, La Raja, Carlotta, Spinelli, Antonino, Massaron, Simonetta, De Nardi, Paola, Kauffmann, Emanuele Federico, Boggi, Ugo, Deidda, Simona, Zorcolo, Luigi, Marano, Alessandra, Borghi, Felice, Piccoli, Micaela, Depalma, Norma, D'Ugo, Stefano, Spampinato, Marcello, Cozzani, Federico, Del Rio, Paolo, Marcellinaro, Rosa, Carlini, Massimo, De Rosa, Raffaele, Scabini, Stefano, Maiello, Fabio, Polastri, Roberto, Turri, Giulia, Pedrazzani, Corrado, Zese, Monica, Parini, Dario, and Coratti, Andrea
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robotic ,COVID-19 ,laparoscopic ,minimally invasive surgery - Published
- 2023
29. Metastatic Melanoma: A Rare Cause of Gastrointestinal Intussusception under Nivolumab
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Deidda Simona, Schirru Rita, Ippolito Luca, Favale Agnese, Cabras Francesco, Onali Sara, Restivo Angelo, Fantini Massimo C, and Zorcolo Luigi
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Cultural Studies ,Education - Published
- 2022
30. Predictors of surgical outcomes of minimally invasive right colectomy: the MERCY study
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de’Angelis, Nicola, Pattacini, Gianmaria Casoni, Winter, Des C., Aisoni, Filippo, Bianchi, Giorgio, Carcoforo, Paolo, Celentano, Valerio, Coccolini, Federico, Di Saverio, Salomone, Frontali, Alice, Denet, Christine, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Antonot, Céphise, Vertier, Jeanne, Le Roy, Bertrand, Lupinacci, Renato Micelli, Martínez-Perez, Aleix, De Palma, Giovanni Domenico, Milone, Marco, Orci, Lorenzo, Bartoletti, Sebastiano, O’Connell, Lauren, Ortenzi, Monica, Paquet, Jean-Christophe, Perrotto, Ornella, Petri, Roberto, Santangelo, Antonio, Scabini, Stefano, De Rosa, Raffaele, Tonini, Valeria, Valverde, Alain, Andolfi, Enrico, Pecchini, Francesca, Pellino, Gianluca, Urbani, Alessia, Vidal, Laura, Restivo, Angelo, Deidda, Simona, Zorcolo, Luigi, Ris, Frederic, Espin, Eloy, Piccoli, Micaela, de’Angelis, Nicola, Pattacini, Gianmaria Casoni, Winter, Des C., Aisoni, Filippo, Bianchi, Giorgio, Carcoforo, Paolo, Celentano, Valerio, Coccolini, Federico, Di Saverio, Salomone, Frontali, Alice, Denet, Christine, Fuks, David, Genova, Pietro, Guerrieri, Mario, Kraft, Miquel, Lakkis, Zaher, Antonot, Céphise, Vertier, Jeanne, Le Roy, Bertrand, Lupinacci, Renato Micelli, Martínez-Perez, Aleix, De Palma, Giovanni Domenico, Milone, Marco, Orci, Lorenzo, Bartoletti, Sebastiano, O’Connell, Lauren, Ortenzi, Monica, Paquet, Jean-Christophe, Perrotto, Ornella, Petri, Roberto, Santangelo, Antonio, Scabini, Stefano, De Rosa, Raffaele, Tonini, Valeria, Valverde, Alain, Andolfi, Enrico, Pecchini, Francesca, Pellino, Gianluca, Urbani, Alessia, Vidal, Laura, Restivo, Angelo, Deidda, Simona, Zorcolo, Luigi, Ris, Frederic, Espin, Eloy, Piccoli, Micaela, De'Angelis, N., Pattacini, G. C., Winter, D. C., Aisoni, F., Bianchi, G., Carcoforo, P., Celentano, V., Coccolini, F., Di Saverio, S., Frontali, A., Denet, C., Fuks, D., Genova, P., Guerrieri, M., Kraft, M., Lakkis, Z., Antonot, C., Vertier, J., Le Roy, B., Lupinacci, R. M., Martinez-Perez, A., De Palma, G. D., Milone, M., Orci, L., Bartoletti, S., O'Connell, L., Ortenzi, M., Paquet, J. -C., Perrotto, O., Petri, R., Santangelo, A., Scabini, S., De Rosa, R., Tonini, V., Valverde, A., Andolfi, E., Pecchini, F., Pellino, G., Urbani, A., Vidal, L., Restivo, A., Deidda, S., Zorcolo, L., Ris, F., Espin, E., and Piccoli, M.
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Colonic Neoplasm ,Anastomosis ,Anastomosis, Surgical ,Operative Time ,Gastroenterology ,Right colectomy ,Intracorporeal anastomosis ,Robotic surgery ,Intracorporeal anastomosi ,Colon cancer ,Cohort Studies ,Treatment Outcome ,Robotic Surgical Procedures ,Retrospective Studie ,Minimally invasive surgery ,Surgical ,Colonic Neoplasms ,Laparoscopy ,Colectomy ,Humans ,Retrospective Studies ,Cohort Studie ,Human - Abstract
PURPOSE: The optimal approach for minimally invasive (MIS) right colectomy remains under debate. This study aimed to describe surgical trends in the treatment of nonmetastatic right colon cancer and to identify predictors of short-term surgical outcomes. METHODS: A retrospective multicenter cohort study of Minimally-invasivE surgery for oncologic Right ColectomY (MERCY) was conducted on patients who underwent laparoscopic or robotic right colectomy between 2014 and 2020. Classification tree approach was used to describe the extracorporeal (EA) or intracorporeal (IA) anastomosis choice. Mixed-model regressions were used to identify patient- and surgery-related factors predictive of postoperative outcomes. A questionnaire was used to evaluate the surgeons' perspectives. RESULTS: The MERCY database comprised 1870 patients; 87.2% underwent laparoscopy, and 68.1% received an EA. A clear surgical trend was noted, with an increasing rate of IA and robotic procedures after 2017. EA represented 41% of anastomoses in centers equipped with a robotic surgical system. Mixed-model regressions (on 1088 patients) showed that age, sex, BMI, comorbidity, robotics, IA, and conversion to open surgery were predictors of surgical outcomes. In particular, IA was a predictor of a shorter time to regular diet and fewer surgical site infections. Based on the questionnaire, IA was the preferred over EA by 72% of surgeons. CONCLUSION: MIS continues to evolve, with an increasing number of IA being performed in the recent years and when using a robotic surgical system. Understanding the role of predictors of surgical outcomes may help surgeons personalize decision-making among the different MIS options to manage right colon cancer.
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- 2022
31. Impact of operation duration on postoperative outcomes of minimally-invasive right colectomy
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de'Angelis, Nicola, Schena, Carlo Alberto, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Pecchini, Francesca, Winter, Des C, O'Connell, Lauren, Carcoforo, Paolo, Urbani, Alessia, Aisoni, Filippo, Martínez-Pérez, Aleix, Celentano, Valerio, Chiarugi, Massimo, Tartaglia, Dario, Coccolini, Federico, Arces, Francesco, Di Saverio, Salomone, Frontali, Alice, Fuks, David, Denet, Christine, Genova, Pietro, Guerrieri, Mario, Ortenzi, Monica, Kraft, Miquel, Pellino, Gianluca, Vidal, Laura, Lakkis, Zaher, Antonot, Céphise, Perrotto, Ornella, Vertier, Jeanne, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, De Palma, Giovanni Domenico, Petri, Roberto, Santangelo, Antonio, Scabini, Stefano, De Rosa, Raffaele, Tonini, Valeria, Valverde, Alain, Bianchi, Giorgio, Carra, Maria Clotilde, Zorcolo, Luigi, Deidda, Simona, Restivo, Angelo, Andolfi, Enrico, Paquet, Jean-Christophe, Bartoletti, Sebastiano, Orci, Lorenzo, Ris, Frederic, Espin, Eloy, De'Angelis, Nicola, Schena, Carlo Alberto, Piccoli, Micaela, Casoni Pattacini, Gianmaria, Pecchini, Francesca, Winter, Des C, O'Connell, Lauren, Carcoforo, Paolo, Urbani, Alessia, Aisoni, Filippo, Martínez-Pérez, Aleix, Celentano, Valerio, Chiarugi, Massimo, Tartaglia, Dario, Coccolini, Federico, Arces, Francesco, Di Saverio, Salomone, Frontali, Alice, Fuks, David, Denet, Christine, Genova, Pietro, Guerrieri, Mario, Ortenzi, Monica, Kraft, Miquel, Pellino, Gianluca, Vidal, Laura, Lakkis, Zaher, Antonot, Céphise, Perrotto, Ornella, Vertier, Jeanne, Le Roy, Bertrand, Micelli Lupinacci, Renato, Milone, Marco, De Palma, Giovanni Domenico, Petri, Roberto, Santangelo, Antonio, Scabini, Stefano, De Rosa, Raffaele, Tonini, Valeria, Valverde, Alain, Bianchi, Giorgio, Carra, Maria Clotilde, Zorcolo, Luigi, Deidda, Simona, Restivo, Angelo, Andolfi, Enrico, Paquet, Jean-Christophe, Bartoletti, Sebastiano, Orci, Lorenzo, Ris, Frederic, Espin, Eloy, and de'Angelis, Nicola
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right colectomy ,Gastroenterology ,laparoscopy ,robotic right colectomy ,operating time ,minimally-invasive surgery - Abstract
Aim: Operation time (OT) is a key operational factor influencing surgical outcomes. The present study aimed to analyse whether OT impacts on short-term outcomes of minimally-invasive right colectomies by assessing the role of surgical approach (robotic [RRC] or laparoscopic right colectomy [LRC]), and type of ileocolic anastomosis (i.e., intracorporal [IA] or extra-corporal anastomosis [EA]). Methods: This was a retrospective analysis of the Minimally-invasivE surgery for oncological Right ColectomY (MERCY) Study Group database, which included adult patients with nonmetastatic right colon adenocarcinoma operated on by oncological RRC or LRC between January 2014 and December 2020. Univariate and multivariate analyses were used. Results: The study sample was composed of 1549 patients who were divided into three groups according to the OT quartiles: (1) First quartile
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- 2022
32. Limits of Clinical Restaging in Detecting Responders After Neoadjuvant Therapies for Rectal Cancer.
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Deidda, Simona, Spolverato, Gaya, Capelli, Giulia, Bao, Riccardo Quoc, Bettoni, Lorenzo, Crimì, Filippo, Zorcolo, Luigi, Pucciarelli, Salvatore, and Restivo, Angelo
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- 2023
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33. Verifying the Theory of Climate Affecting Lethality of COVID-19 by an Analysis in Two Climatic Zones of Chile
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Aviles-Gonzalez, Cesar Ivan, primary, Scano, Alessandra, additional, Cossu, Giulia, additional, Littera, Roberto, additional, Campagna, Marcello, additional, Deidda, Simona, additional, Romano, Ferdinando, additional, Kalcev, Goce, additional, Firinu, Davide, additional, Meloni, Federico, additional, Carta, Mauro Giovanni, additional, Del Giacco, Stefano, additional, Restivo, Angelo, additional, Zorcolo, Luigi, additional, Marongiu, Luigi, additional, Tamburini, Giorgio, additional, Maleci, Alberto, additional, Orrù, Germano, additional, Chessa, Luchino, additional, and Brasesco, María Verónica, additional
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- 2022
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34. Mismatch repair proteins (MMR) expression as predictive factor in locally advanced rectal cancer.
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Pretta, Andrea, primary, Donisi, Clelia, additional, Persano, Mara, additional, Pinna, Giovanna, additional, Cimbro, Erika, additional, Parrino, Alissa, additional, Aimola, Valentina, additional, Spanu, Dario, additional, Cerrone, Giulia, additional, Deidda, Simona, additional, Deidda, Maria Assunta, additional, Lai, Eleonora, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, Ziranu, Pina, additional, Barbara, Raffaele, additional, Restivo, Angelo, additional, Zorcolo, Luigi, additional, Faa, Gavino, additional, and Scartozzi, Mario, additional
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- 2022
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35. Association of Delayed Surgery With Oncologic Long-term Outcomes in Patients With Locally Advanced Rectal Cancer Not Responding to Preoperative Chemoradiation
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Deidda, Simona, primary, Elmore, Ugo, additional, Rosati, Riccardo, additional, De Nardi, Paola, additional, Vignali, Andrea, additional, Puccetti, Francesco, additional, Spolverato, Gaya, additional, Capelli, Giulia, additional, Zuin, Matteo, additional, Muratore, Andrea, additional, Danna, Riccardo, additional, Calabrò, Marcello, additional, Guerrieri, Mario, additional, Ortenzi, Monica, additional, Ghiselli, Roberto, additional, Scabini, Stefano, additional, Aprile, Alessandra, additional, Pertile, Davide, additional, Sammarco, Giuseppe, additional, Gallo, Gaetano, additional, Sena, Giuseppe, additional, Coco, Claudio, additional, Rizzo, Gianluca, additional, Pafundi, Donato Paolo, additional, Belluco, Claudio, additional, Innocente, Roberto, additional, Degiuli, Maurizio, additional, Reddavid, Rossella, additional, Puca, Lucia, additional, Delrio, Paolo, additional, Rega, Daniela, additional, Conti, Pietro, additional, Pastorino, Alessandro, additional, Zorcolo, Luigi, additional, Pucciarelli, Salvatore, additional, Aschele, Carlo, additional, and Restivo, Angelo, additional
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- 2021
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36. Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue
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Vega-Benedetti, Ana Florencia, primary, Loi, Eleonora, additional, Moi, Loredana, additional, Restivo, Angelo, additional, Cabras, Francesco, additional, Deidda, Simona, additional, Pretta, Andrea, additional, Ziranu, Pina, additional, Orrù, Sandra, additional, Scartozzi, Mario, additional, Zorcolo, Luigi, additional, and Zavattari, Patrizia, additional
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- 2021
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37. The Covid-19 Incidence in Italian Regions Correlates with Low Temperature, Mobility and Pm10 Pollution but Lethality Only with Low Temperature
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Carta, Mauro Giovanni, primary, Minerba, Luigi, additional, Demontis, Roberto, additional, Orrù, Germano, additional, Romano, Ferdinando, additional, Scano, Alessandra, additional, Restivo, Angelo, additional, Del Giacco, Stefano, additional, Deidda, Simona, additional, Firinu, Davide, additional, Campagna, Marcello, additional, Meloni, Federico, additional, Cossu, Giulia, additional, Sancassiani, Federica, additional, Chessa, Luchino, additional, Kalcev, Goce, additional, Littera, Roberto, additional, Zorcolo, Luigi, additional, Aviles-Gonzales, Cesar Ivan, additional, and Usai, Paolo, additional
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- 2021
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38. Mismatch Repair system protein deficiency as a factor of resistance to chemo-radiotherapy treatment in patients with locally advanced rectal adenocarcinoma and its influence on disease-free survival.
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Pretta, Andrea, Ziranu, Pina, Giampieri, Riccardo, Donisi, Clelia, Pinna, Giovanna, Randon, Giovanni, Loi, Francesco, Deias, Giulia, Palmas, Enrico, Morano, Federica, Solinas, Cinzia, Lai, Eleonora, Pusceddu, Valeria, Puzzoni, Marco, Zorcolo, Luigi, Barbara, Raffaele, Faa, Gavino, Berardi, Rossana, Pietrantonio, Filippo, and Scartozzi, Mario
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- 2023
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39. Right Colectomy with Intracorporeal Anastomosis: A European Multicenter Propensity Score Matching Retrospective Study of Robotic Versus Laparoscopic Procedures.
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de'Angelis N, Piccoli M, Casoni Pattacini G, Winter DC, Carcoforo P, Celentano V, Coccolini F, Di Saverio S, Frontali A, Fuks D, Genova P, Guerrieri M, Kraft M, Lakkis Z, Le Roy B, Micelli Lupinacci R, Milone M, Petri R, Scabini S, Tonini V, Valverde A, Zorcolo L, Bianchi G, Ris F, and Espin E
- Subjects
- Humans, Retrospective Studies, Propensity Score, Colectomy methods, Anastomosis, Surgical methods, Treatment Outcome, Operative Time, Robotic Surgical Procedures methods, Colonic Neoplasms surgery, Colonic Neoplasms pathology, Laparoscopy methods
- Abstract
Background: This study aimed to compare the short- and long-term outcomes of robotic (RRC-IA) versus laparoscopic (LRC-IA) right colectomy with intracorporeal anastomosis using a propensity score matching (PSM) analysis based on a large European multicentric cohort of patients with nonmetastatic right colon cancer., Methods: Elective curative-intent RRC-IA and LRC-IA performed between 2014 and 2020 were selected from the MERCY Study Group database. The two PSM-groups were compared for operative and postoperative outcomes, and survival rates., Results: Initially, 596 patients were selected, including 194 RRC-IA and 402 LRC-IA patients. After PSM, 298 patients (149 per group) were compared. There was no statistically significant difference between RRC-IA and LRC-IA in terms of operative time, intraoperative complication rate, conversion to open surgery, postoperative morbidity (19.5% in RRC-IA vs. 26.8% in LRC-IA; p = 0.17), or 5-yr survival (80.5% for RRC-IA and 74.7% for LRC-IA; p = 0.94). R0 resection was obtained in all patients, and > 12 lymph nodes were harvested in 92.3% of patients, without group-related differences. RRC-IA procedures were associated with a significantly higher use of indocyanine green fluorescence than LRC-IA (36.9% vs. 14.1%; OR: 3.56; 95%CI 2.02-6.29; p < 0.0001)., Conclusion: Within the limitation of the present analyses, there is no statistically significant difference between RRC-IA and LRC-IA performed for right colon cancer in terms of short- and long-term outcomes., (© 2023. The Author(s) under exclusive licence to Société Internationale de Chirurgie.)
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- 2023
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40. The MIS-COVID-AGICT Study: Trend of Minimally Invasive Surgery for Gastrointestinal Cancer Treatment During the First Waves of the COVID-19 Pandemic in Italy. Subgroup Analysis from the COVID-AGICT Study: COVID-19 and Advanced Gastrointestinal Cancer Surgical Treatment.
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Giuliani G, Coletta D, Guerra F, Esposito S, Esposito A, De Pastena M, Rega D, Delrio P, La Raja C, Spinelli A, Massaron S, De Nardi P, Kauffmann EF, Boggi U, Deidda S, Zorcolo L, Marano A, Borghi F, Piccoli M, Depalma N, D'Ugo S, Spampinato M, Cozzani F, Del Rio P, Marcellinaro R, Carlini M, De Rosa R, Scabini S, Maiello F, Polastri R, Turri G, Pedrazzani C, Zese M, Parini D, and Coratti A
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- Humans, Minimally Invasive Surgical Procedures methods, Pandemics, Retrospective Studies, SARS-CoV-2, Treatment Outcome, COVID-19, Gastrointestinal Neoplasms surgery
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Background: A preliminary analysis from the COVID-Advanced Gastrointestinal Cancer Surgical Treatment (AGICT) study showed that the rate of minimally invasive surgery (MIS) for elective and urgent procedures did not decrease during the pandemic year. In this article, we aimed to perform a subgroup analysis using data from the COVID-AGICT study to evaluate the trend of MIS during the COVID-19 pandemic period in Italy. Methods: This study was conducted collecting data of MIS patients from the COVID-AGICT database. The primary endpoint was to demonstrate whether the SARS-CoV-2 pandemic scenario reduced MIS for elective treatment of gastrointestinal cancer (GIC) in Italy in 2020. The secondary endpoint was to evaluate the impact of the pandemic period on perioperative outcomes in the MIS group. Results: In the pandemic year, 62% of patients underwent surgery with a minimally invasive approach, compared to 63% in 2019 ( P = .23). In 2020, the proportion of patients undergoing elective MIS decreased compared to the previous year (80% versus 82%, P = .04), and the rate of urgent MIS did not differ between the 2 years (31% and 33% in 2019 and 2020 - P = .66). Colorectal cancer was less likely to be treated with MIS approach during 2020 (78% versus 75%, P < .001). Conversely, the rate of MIS pancreatic resection was higher in 2020 (28% versus 22%, P < .002). Conversion to an open approach was lower in 2020 (7.2% versus 9.2% - P = .01). Major postoperative complications were similar in both years (11% versus 11%, P = .9). Conclusion: In conclusion, although MIS for elective treatment of GIC in Italy was reduced during the COVID-19 pandemic period, our study revealed that the overall proportion of MIS (elective and urgent) and postoperative outcomes were comparable to the prepandemic period. ClinicalTrial.gov (NCT04686747).
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- 2023
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41. Conversion to Open Surgery During Minimally Invasive Right Colectomy for Cancer: Results from a Large Multinational European Study.
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Martínez-Pérez A, Piccoli M, Casoni Pattacini G, Winter DC, Carcoforo P, Celentano V, Chiarugi M, Di Saverio S, Bianchi G, Frontali A, Fuks D, Genova P, Guerrieri M, Kraft M, Lakkis Z, Le Roy B, Micelli Lupinacci R, Milone M, Petri R, Scabini S, Tonini V, Valverde A, Zorcolo L, Ris F, Espin E, and de'Angelis N
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- Humans, Male, Neoplasm Recurrence, Local surgery, Colectomy methods, Postoperative Complications etiology, Retrospective Studies, Treatment Outcome, Minimally Invasive Surgical Procedures methods, Colonic Neoplasms surgery, Robotic Surgical Procedures methods, Laparoscopy methods
- Abstract
Background: The risk of conversion to open surgery is inevitably present during any minimally invasive colorectal surgical procedure. Conversions have been associated with adverse postoperative and oncologic outcomes. No previous study has evaluated the specific causes and consequences of conversion during a minimally invasive right colectomy (MIS-RC). Materials and Methods: We analyzed the Minimally invasivE surgery for oncologic Right ColectomY (MERCY) study database including patients who underwent laparoscopic or robotic RC because of colon cancer between 2014 and 2020. Descriptive analyses were performed to determine the different reasons for conversion. Uni- and multivariate logistic regressions were run to identify potential variables associated with this outcome. Cox regression analyses were used to evaluate the impact of conversion on tumor recurrence. Results: Over a total of 1574 MIS-RC, 120 (7.6%) were converted to open surgery. The main reasons for conversion were procedural difficulties related to adherences from previous abdominal surgical procedures (39.2%), or owing to large tumor size or infiltration of adjacent structures (26.7%). Only 16.7% of the conversions were caused by intraoperative medical or surgical complications. Converted patients required longer operative times and developed more postoperative complications, both overall (39.2% versus 27.5%; P = .006) and severe ones (13.3% versus 8.3%; P = .061). Male gender (odds ratio [OR] = 1.89 [95% confidence interval: 1.31-2.71]), obesity (OR = 1.99 [1.4-2.83]), prior abdominal surgery (OR = 1.68 [1.19-2.37]), and pT4 cancers (OR = 4.04 [2.86-5.69]) were independently associated with conversion. Conversion to open surgery was not significantly associated with tumor recurrence (hazard ratios = 1.395 [0.724-2.687]). Conclusions: Although conversion to open surgery during MIS-RC for cancer is associated with worsened postoperative outcomes, it seems not to impact on the oncologic prognosis.
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- 2023
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42. Impact of operation duration on postoperative outcomes of minimally-invasive right colectomy.
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de'Angelis N, Schena CA, Piccoli M, Casoni Pattacini G, Pecchini F, Winter DC, O'Connell L, Carcoforo P, Urbani A, Aisoni F, Martínez-Pérez A, Celentano V, Chiarugi M, Tartaglia D, Coccolini F, Arces F, Di Saverio S, Frontali A, Fuks D, Denet C, Genova P, Guerrieri M, Ortenzi M, Kraft M, Pellino G, Vidal L, Lakkis Z, Antonot C, Perrotto O, Vertier J, Le Roy B, Micelli Lupinacci R, Milone M, De Palma GD, Petri R, Santangelo A, Scabini S, De Rosa R, Tonini V, Valverde A, Bianchi G, Carra MC, Zorcolo L, Deidda S, Restivo A, Andolfi E, Paquet JC, Bartoletti S, Orci L, Ris F, and Espin E
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- Adult, Humans, Male, Retrospective Studies, Colectomy adverse effects, Anastomosis, Surgical adverse effects, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications surgery, Treatment Outcome, Operative Time, Colonic Neoplasms surgery, Colonic Neoplasms etiology, Adenocarcinoma surgery, Adenocarcinoma etiology, Robotic Surgical Procedures, Laparoscopy adverse effects
- Abstract
Aim: Operation time (OT) is a key operational factor influencing surgical outcomes. The present study aimed to analyse whether OT impacts on short-term outcomes of minimally-invasive right colectomies by assessing the role of surgical approach (robotic [RRC] or laparoscopic right colectomy [LRC]), and type of ileocolic anastomosis (i.e., intracorporal [IA] or extra-corporal anastomosis [EA])., Methods: This was a retrospective analysis of the Minimally-invasivE surgery for oncological Right ColectomY (MERCY) Study Group database, which included adult patients with nonmetastatic right colon adenocarcinoma operated on by oncological RRC or LRC between January 2014 and December 2020. Univariate and multivariate analyses were used., Results: The study sample was composed of 1549 patients who were divided into three groups according to the OT quartiles: (1) First quartile, <135 min (n = 386); (2) Second and third quartiles, 135-199 min (n = 731); and (3) Fourth quartile ≥200 min (n = 432). The majority (62.7%) were LRC-EA, followed by LRC-IA (24.3%), RRC-IA (11.1%), and RRC-EA (1.9%). Independent predictors of an OT ≥ 200 min included male gender, age, obesity, diabetes, use of indocyanine green fluorescence, and IA confection. An OT ≥ 200 min was significantly associated with an increased risk of postoperative noninfective complications (AOR: 1.56; 95% CI: 1.15-2.13; p = 0.004), whereas the surgical approach and the type of anastomosis had no impact on postoperative morbidity., Conclusion: Prolonged OT is independently associated with increased odds of postoperative noninfective complications in oncological minimally-invasive right colectomy., (© 2022 Association of Coloproctology of Great Britain and Ireland.)
- Published
- 2022
- Full Text
- View/download PDF
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