Search

Abstract Hierarchical Bi2Fe4O9/BiOI S-scheme nanoflower heterostructures are prepared by hydrothermal method, which exhibit exceptional photo-piezoelectric catalytic performance. The tight binding between the sheets ensures the efficient electron transport, and provides a large interface area and adequate reaction sites for photo-piezoelectric catalytic reactions. At the same time, because the water flow in the water body produces hydraulic shear force on the material, the material produces piezoelectric effect. Bi2Fe4O9/BiOI exhibit a remarkable degradation efficiency of 99.4% for tetracycline and a hydrogen production rate of 4089.36 µmol h−1 g−1. The observed behavior can be explained by the combined influence of the formation of S-scheme structure and the process of photo-piezoelectric catalysis, confirmed by in-situ XPS, transient/steady-state fluorescence and piezoelectric response force test. The excellent stability of the material suggests its possible use in the sectors of energy and environment. This work introduces novel concepts for the future advancement of photo-piezoelectric synergistic catalysis.

Previous research has indicated that students’ academic engagement is related to their emotional support from teachers. However, there is scarce evidence on how teacher emotional support relates to students’ academic engagement. Given the potential role of positive academic emotions in learning, this study investigated the mediating role of students’ positive academic emotions in the relationship between teacher emotional support and academic engagement among Chinese college students. Additionally, this study examined how mastery-approach goals moderated positive academic emotions. A survey instrument containing teacher emotional support, positive academic emotions, mastery-approach goals, and academic engagement was administered to 464 Chinese college students. The results demonstrated that students’ emotional support from their teachers positively influenced their academic engagement. Positive academic emotions mediated the relationship between teacher emotional support and students’ academic engagement. Furthermore, the mastery-approach goals moderated the mediating role of positive academic emotions. Finally, the implications for teachers in teaching for practice and the application prospects are discussed.

Aims We investigated the incidence and clinical features of venous thromboembolism (VTE) in inpatients with mental illnesses. Methods We retrospectively analyzed records of inpatients with mental illnesses and confirmed VTE at The First Hospital of Hebei Medical University between August 2018 and July 2022. We recorded demographic characteristics, psychosis-related conditions, and thrombus distribution. Results Among 12939 patients diagnosed with mental illness, 156 (1.21%) presented with VTE at the first visit or during the disease course. Crude VTE incidence varied significantly across mental illnesses, being highest in patients with organic mental disorders (5.20%), followed by emotional disorders (1.10%), and others ( P

ABSTRACT: Intravascular fasciitis (IVF) is a special type of nodular fasciitis, which is very rare. It is often misdiagnosed as malignant tumor or deep vein thrombosis by imaging examination before operation. Pathological examination can make a definite diagnosis, and surgical resection can cure it and which with little recurrence. In this case, a 22-year-old young man presented with a 3-day history of swelling and pain of the right lower limb, and suspected deep venous thrombosis of the lower limb by ultrasound examination in local hospital. We further performed CT examination for him and which suggested that the right common femoral vein occupied. Surgical removal of the venous mass and pathological examination were performed to finally diagnose the intravascular nodular fasciitis. After 3 months of operation, CT examination showed that the disease recurred and conservative treatment was given. After 1 month of follow-up, the volume of space-occupying lesions decreased, and after 6 months of follow-up, CT examination showed that the original space-occupying lesions disappeared. This paper describes the course, diagnosis and treatment of the patient in detail, aiming at improving people's understanding of the disease and reducing misdiagnosis and excessive treatment.

Tilapia (Oreochromis sp.) is one of the important economical fishes in the world. Streptococcosis is commonly found in tilapia, causing severe and devastating effects in tilapia cultures. Streptococcus agalactiae and Streptococcus iniae are the predominant pathogens causing tilapia streptococcosis. To understand the molecular mechanisms underlying differential streptococcal infection patterns, Nile tilapias (Oreochromis niloticus) were infected by 1 × 107 CFU/mL S. agalactiae, 1 × 107 CFU/mL S. iniae, and 1 × 107 CFU/mL S. agalactiae and S. iniae (1:1), respectively, and transcriptome analysis was conducted to the intestine samples of Nile tilapia (Oreochromis niloticus) at 6, 12, 24 h, and 7 days post-infection. A total of 6,185 genes that differentially expressed among groups were identified. Eight differentially expressed genes (DEGs) including E3 ubiquitin-protein ligase TRIM39-like, C-X-C motif chemokine 10-like(CXCL 10), C-C motif chemokine 19-like, interleukin-1 beta-like, IgM heavy chain VH region, partial, IgG Fc-binding protein, proteasome subunit beta type-8 (PSMB8), and ATP synthase F(0) complex subunit B1, mitochondrial that involved in the immune system were selected, and their expression levels in the coinfection group were significantly higher than those in either of the single infection groups. These genes were associated with four different KEGG pathways. Additionally, the differential expression of eight DEGs was validated by using the RT-qPCR approach, and their immunological importance was discussed. The results provided insights into the responses of tilapia against S. agalactiae and S. iniae at the transcriptome level, promoting our better understanding of immune responses for aquatic animal against Streptococcus.

Background and objectiveWhile the six-minute walk test (6MWT) is often used to assess exercise capacity, the less well-known two-minute walk test (2MWT) is more feasible for some patients. In previous studies, we developed reference equations for the two-minute walk distance (2MWD) for healthy Chinese adults. However, our study did not recruit people with obesity, and the reference equations did not apply to participants with a body mass index (BMI) > 30 kg/m2. The main objective of this study was to establish reference equations for the 2MWD among middle-aged and elderly Chinese individuals with obesity.MethodsA total of 295 individuals were recruited. The participants underwent two 2MWTs, with the longer of the two 2MWDs used for further analyses. The reference equations for the 2MWD were developed using stepwise multiple regression analysis. The newly established equations for the 2MWD were then compared with the existing equations.ResultsThe mean 2MWD of the participants was 176±20 m. Age and BMI were identified as independent factors that influenced the 2MWD and explained 28% and 32% of the variance in walking distance for the male and female groups, respectively. The reference equations for the 2MWD were as follows: [Formula: see text].ConclusionThis study resulted in the development of reference equations for predicting 2MWD among middle-aged and elderly Chinese people with obesity. These equations will be a clinically valuable tool for evaluating functional capacity, determining prognoses and monitoring treatment in middle-aged and elderly Chinese people with obesity.

Because of their low expense and ease of rapid deployment, unmanned aerial vehicles (UAVs) are frequently applied in wireless networks. Although the wireless channel is able to broadcast, legitimate communications between UAVs and ground nodes are incredibly susceptible to severe security threats, such as malicious jamming and eavesdropping. Compared with the traditional line-of-sight channel (LC) model, the probabilistic LC (PrLC) model can better describe the practical channel conditions of UAV-to-ground transmission in city areas. Therefore, this paper considers the UAV-enabled networks under the PrLC model in complex city environments. Specifically, when the UAV transmits classified messages to legitimate ground nodes, multiple active eavesdroppers simultaneously eavesdrop on the transmitted confidential information to interfere with the signal and limit the legal transmission. We jointly optimize the communication connection, the three-dimensional (3D) UAV trajectory, and the transmit power of the UAV to increase the average secrecy rate for the worst condition. Because the problem is non-convex, the best solution is formidable to get, this paper designs an iterative algorithm and use the successive convex approximation (SCA) technique to solve it. Compared to other benchmarks, our proposed algorithm, as demonstrated by numerical results, can effectively balance the elevation angle-distance trade-off to improve secrecy rate performance.

Background: Protein kinase G type II (PKG II) is a serine/threonine-protein kinase that was originally isolated from the small intestinal mucosa with primary functions in the secretion of small intestinal mucosal cells, secretion of renin and aldosterone, and chondrocyte activities. Recent studies have shown that PKG II exerts anti-tumor effects, while a previous study by our group confirmed that PKG II inhibited the proliferation and migration of cancer cells. Interestingly, PKG II, which was typically bound to the intracellular side of the membrane, was detected in the serum and cell culture medium as a diagnostic biomarker of tumor growth. Thus, the aim of the present study was to elucidate the function and the targets of PKG II, and the mechanism underlying the secretion of this kinase. Methods: Construction of peptides and plasmids, RNA interference, Immunoelectron microscopy, Co-immunoprecipitation, N-glycosylation assay and Isolation of the Golgi apparatus were applied to investigate the secretory mechanism, and the targets and function of PKG II. Results: PKG II was secreted by enterochromaffin (EC) cells, which were components of the endocrine system in the gastrointestinal tract. Myristoylation of glycine 2 and the N-terminal sequence, especially the amino acids 3–30, acted as a signal peptide to induce the secretion of PKG II via the conventional protein secretory pathway. Moreover, recombinant PKG II inhibited the epidermal growth factor (EGF)-induced activation of the EGF receptor via phosphorylating the T406 of the extracellular domain and blocked EGF-triggered proliferation of various cancer cells. Conclusions: These results revealed a correlation between the endocrine system and the secretion of protein kinase, suggesting a novel protein secretory pathway. The resuls also indicated that secreted PKG II was a potential diagnostic biomarker and an inhibitor of tumor.

As a management strategy, community participation is to implement the coordinated development of communities and protected areas. In recent years, the development of China’s national parks has faced many challenges related to human and environmental constraints. Community participation plays an essential role in solving such issues. As one of the critical indicators to test community participation, community residents’ willingness to participate significantly impacts community participation in constructing national parks. As such, this study was conducted using the extended model of the theory of planned behavior (TPB) and the structural equation model. Taking the Tianzhu county and Sunan Yugu county as examples, and based on 230 valid questionnaires, we investigated the impacts of the Qilian Mountain National Park System Pilot Area on community residents’ willingness to participate and provided relevant suggestions for amendments. The results indicated that, for the Qilian Mountain National Park System Pilot Area, behavioral attitude, subjective norms, and perceptual behavior control positively impacted the participation intention of community residents. At the same time, the variables mentioned above positively impacted the implementation of the participation intention of community residents. Specifically, the order of impacts is as follows: perceptual behavior control (path coefficient = 0.89) > participation behavior attitude (path coefficient = 0.68) > related impact system (path coefficient = 0.41) > subjective norms (path coefficient = 0.38). According to the results, we put forward three suggestions: (1) providing relevant instructions and guidance on various methods to ensure that the pilot policies on the construction of national parks can form a positive relationship with the participation intentions of the community residents; (2) making full use of the function of perceptual behavior control, so the subjective initiative of community residents can be maximized, thereby enhancing the willingness of community residents to participate in constructing national parks; and (3) strengthening the impacts of subjective norms, enhancing the soft culture of national park communities’ participation, reshaping the community cultural landscapes with the goal of constructing national parks, and establishing community residents’ sense of honor as the builders of national parks.

CLEC12A, a member of the C-type lectin receptor family involved in immune homeostasis, recognizes MSU crystals released from dying cells. However, the molecular mechanism underlying the CLEC12A-mediated recognition of MSU crystals remains unclear. Herein, we reported the crystal structure of the human CLEC12A-C-type lectin-like domain (CTLD) and identified a unique "basic patch" site on CLEC12A-CTLD that is necessary for the binding of MSU crystals. Meanwhile, we determined the interaction strength between CLEC12A-CTLD and MSU crystals using single-molecule force spectroscopy. Furthermore, we found that CLEC12A clusters at the cell membrane and seems to serve as an internalizing receptor of MSU crystals. Altogether, these findings provide mechanistic insights for understanding the molecular mechanisms underlying the interplay between CLEC12A and MSU crystals. [ABSTRACT FROM AUTHOR]