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The physical and chemical properties of nanometal materials, along with their expansive market potential, have garnered widespread attention, especially in the field of catalysis, where they exhibit remarkable performance. With the in-depth study of the catalytic properties of nanometal materials, this paper aims to systematically explore their characteristics, preparation methods, and applications in various catalytic fields, providing a scientific basis for catalyst design and development, and contributing to environmental issues and enhancement of synthesis efficiency. Utilizing methods such as electrochemical deposition and physical vapor deposition, nanometal materials with catalytic properties have been obtained. Nanometal materials with different physical properties can be applied in various fields such as bioimaging, photocatalysis, electrocatalysis, and organic synthesis, revealing that nanometal materials possess abundant binding sites, excellent electron transfer properties, and corrosion resistance. Through this research, not only a scientific basis for catalyst design and development is provided, but also outstanding contributions are expected to be made to environmental issues and enhancement of synthesis efficiency. At the same time, by applying them in fields such as bioimaging, positive impacts are brought to the development of science and medicine.

Microsporidia are intracellular eukaryotic pathogens that pose a substantial threat to immunocompromised hosts. The way these pathogens manipulate host cells during infection remains poorly understood. Using a proximity biotinylation strategy we established that microsporidian EnP1 is a nucleus-targeted effector that modifies the host cell environment. EnP1's translocation to the host nucleus is meditated by nuclear localization signals (NLSs). In the nucleus, EnP1 interacts with host histone H2B. This interaction disrupts H2B monoubiquitination (H2Bub), subsequently impacting p53 expression. Crucially, this inhibition of p53 weakens its control over the downstream target gene SLC7A11, enhancing the host cell's resilience against ferroptosis during microsporidian infection. This favorable condition promotes the proliferation of microsporidia within the host cell. These findings shed light on the molecular mechanisms by which microsporidia modify their host cells to facilitate their survival., Competing Interests: Competing interests statement:The authors declare no competing interest.