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Studies have shown that a very wide range of parameters affect thermal comfort of building occupants. Heat transfer through the roofs has been identified as one of the causes of overheating in building interiors. Building Performance Simulation tools can be used to determine appropriate roof design parameters with optimum thermal performance in tropical climates like Nigeria. However, ensuring the reliability of the simulation results is essential for both occupants and designers. Therefore, this study seeks to verify and validate the accuracy of simulation results of DesignBuilder as a simulation tool for the present research works on roof thermal performance. The study primarily focuses on the impact of roof design on the air temperature in the indoor learning environment. Validation is examined by comparing the measured daily indoor air temperature of Kofar Wambai Secondary School Classroom, Bauchi city data and the simulation results. Comparative analysis indicate that the % deviation of field measured and simulated results for the tested days (18th and 21st September, 2018) were 2.39% and 1.25% respectively. The R2 results indicated 99% and 75% correlation between the simulated and measured indoor temperature on the tested days.These results agreed with the recommendations of a study by (Andelkovic et al, 2016) which reported that the marginal value of R2 for measurements and simulations validation is R2 ≥ 75%. Therefore, DesignBuilder can be employed to evaluate roof thermal performance as well as predict indoor air temperature of classroom buildings.

Objective: In this study, the effects of resveratrol topical ointment on wound contraction and histopathology of full-thickness cutaneous burn wounds were evaluated. Method: Adult albino rats were grouped into four equal-sized groups of 15 rats each, as follows: Group A—no wound, no treatment (control); Group B—1% silver sulphadiazine; Group C—5% resveratrol, and Group D—wound without treatment (control). A burn wound measuring 23.5mm was created on the skin at the dorsum of all rats in groups B—D after shaving. The percentage of wound contraction was measured using a digital Vernier Caliper on days 1, 3, 5, 7, 10, 14, 16, 18 and 21, post-wounding. From each group, five rats were then euthanised and tissue samples of the skin, liver and kidney were collected in 10% buffered formalin for histopathology. Results: The percentage of wound contraction was significant (pConclusion: In this study, topical application of 5% resveratrol ointment appeared to enhance burn wound healing by increasing the rate of wound contraction through collagen fibre synthesis, granulation tissue formation and epithelial regeneration.

Previous investigations have revealed that lipopolysaccharide (LPS) endotoxin from certain Gram-negative bacteria could adversely affect the reproductive system of female animals. However, it is unknown whether LPS endotoxin of Mannheimia haemolytica serotype A2, the principal causative bacteria that cause pneumonic mannheimiosis in small ruminants, may also induce similar insidious effects. Therefore, this study aimed to investigate the effects of M. haemolytica serotype A2 and its LPS endotoxin on the responses of female gonadal hormones (progesterone and oestrogen), pro-inflammatory cytokines (interleukin-1β, interleukin-6), acute-phase proteins (haptoglobin and serum amyloid A) and cellular changes via histopathology study of female reproductive organs of the treatment does. Twelve clinically healthy, non-pregnant, crossbred does were randomly allocated into three equal groups. Group 1 was administered intranasally with 2 ml of sterile phosphate-buffered saline (PBS) and served as a negative control group. Group 2 was challenged intranasally with 2 ml of bacterial inoculum containing 10