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Your search keyword '"Ye, Caiyong"' showing total 26 results
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26 results on '"Ye, Caiyong"'

3. Research on Structure Optimization of Axial Magnetic Bearing for Magnetic Levitation System

Author

Lu, Jintao, Qin, Chengyu, Deng, Xiao, Han, Linghui, Ye, Caiyong, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Yang, Qingxin, editor, Li, Zewen, editor, and Luo, An, editor

Published
2024
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7. BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.

Author

Kang, Zhihua, Fu, Pan, Alcivar, Allen L, Fu, Haiqing, Redon, Christophe, Foo, Tzeh Keong, Zuo, Yamei, Ye, Caiyong, Baxley, Ryan, Madireddy, Advaitha, Buisson, Remi, Bielinsky, Anja-Katrin, Zou, Lee, Shen, Zhiyuan, Aladjem, Mirit I, and Xia, Bing

Subjects
BRCA2 Protein, Cell Line, Tumor, Cell Survival, DNA Damage, DNA Helicases, DNA Primase, DNA Replication, DNA, Neoplasm, DNA, Single-Stranded, DNA-Binding Proteins, DNA-Directed DNA Polymerase, Gene Expression Regulation, Neoplastic, Genomic Instability, HEK293 Cells, HeLa Cells, Humans, Minichromosome Maintenance Proteins, Multifunctional Enzymes, Osteoblasts, RNA, Small Interfering, Recombinational DNA Repair, Signal Transduction, Transcription Factors, Breast Cancer, Genetics, Cancer, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning
Abstract

The BRCA2 tumor suppressor protects genome integrity by promoting homologous recombination-based repair of DNA breaks, stability of stalled DNA replication forks and DNA damage-induced cell cycle checkpoints. BRCA2 deficient cells display the radio-resistant DNA synthesis (RDS) phenotype, however the mechanism has remained elusive. Here we show that cells without BRCA2 are unable to sufficiently restrain DNA replication fork progression after DNA damage, and the underrestrained fork progression is due primarily to Primase-Polymerase (PRIMPOL)-mediated repriming of DNA synthesis downstream of lesions, leaving behind single-stranded DNA gaps. Moreover, we find that BRCA2 associates with the essential DNA replication factor MCM10 and this association suppresses PRIMPOL-mediated repriming and ssDNA gap formation, while having no impact on the stability of stalled replication forks. Our findings establish an important function for BRCA2, provide insights into replication fork control during the DNA damage response, and may have implications in tumor suppression and therapy response.

Published
2021

12. Vibration Characteristics and Vibration Mitigation Analysis of End Cap PM Excitation Homopolar Inductor Machine

Author

Ye, Caiyong, Qi, Xiaodong, Liu, Kaifeng, Deng, Cong, Fang, Haiyang, and Zhou, Jianlin

Abstract

Vibration analysis and vibration mitigation are very important to ensure the safe and stable operation of electrical machines applied in flywheel energy storage systems. In traditional integer slot synchronous machines, it is generally believed that there is only the zeroth-mode vibration caused by odd tooth harmonics. However, the homopolar inductor machine (HIM) adopts the end cap excitation structure, which makes its air-gap magnetic field contain the dc component, odd tooth harmonics and even tooth harmonics. The force density distribution on the slotted stator is analyzed by the magnetomotive force-multiplying permeance method. The results show that there are both zeroth- and pth(pole pairs)-mode vibrations caused by tooth harmonics and dc component of the air-gap flux density. Furthermore, to reduce vibration and resonance, and to improve the electromagnetic performance of HIM, it is best to use the stator skew slot, the magnetic slot wedge and the sinusoidal rotor slot at the same time. Finally, a 54-slot/6-pole end cap permanent magnet excitation homopolar inductor machine (EPE-HIM) is tested to validate the analytical and the finite-element method (FEM) results, and the variation trend of the experimental results and FEM results is the same.

Published
2023
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