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The grain-oriented silicon steel is an important iron core material, and normalization is an indispensable industrial production process for the production of high magnetic induction grain-oriented silicon steel at present. It can adjust the structure, texture and inhibitor precipitation of hot-rolled band to improve the magnetic properties of silicon steel.The inheritance from hot rolled microstructures to normalized ones of grain-oriented silicon steel and the evolution law of inhibitor during the process of normalizing were summarized, and the influence of normalizing on the microstructure and texture of primary recrystallization and secondary recrystallization was mainly discussed. It is pointed out that the fine γ-oriented grain colonies formed during normalizing favour the final secondary recrystallization whilst the coarse and deformed α-/λ-oriented grains disfavour it. Finally, a three-stage normalization process and its parameters for optimizing magnetic properties of low-temperature heating nitriding type high magnetic induction grain-oriented silicon steel were recommended. The key research direction of normalizing in the future is to further simplify process on the basis of ensuring the same texture and inhibitor content, and rational application of normalizing process in the grain-oriented silicon steel produced by thin slab casting and rolling and strip casting.

Paclitaxel is a widely used anti-tumor drug. Currently, paclitaxel can only be extracted from plants or synthesized by chemical semi-synthesis, which cause environmental damage and cannot meet the growing demand. However, the complete biosynthetic pathway of paclitaxel is still not clear, which greatly limits the production of paclitaxel using methods such as synthetic biology. Here, we deduced the paclitaxel biosynthetic pathway by searching all possible intermediates in the paclitaxel synthesis pathway from the natural product databases. In addition, we performed the transcriptome sequencing of Taxus brevifolia and performed co-expression analysis of the identified genes in the paclitaxel synthesis pathway. All these results laid a solid foundation for the elucidation of paclitaxel biosynthetic pathway.