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Your search keyword '"Xu, Xiangjun"' showing total 125 results
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125 results on '"Xu, Xiangjun"'

6. Calycosin protects against chronic prostatitis in rats via inhibition of the p38MAPK/NF-κB pathway

Author

Wang Heng, He Lei, Liu Zhaofei, Xu Xiangjun, Zhang Haitao, Mao Pengfei, and Li Ming

Subjects
calycosin, chronic prostatitis, p38mapk/nf-κb pathway, Medicine
Abstract

Currently, the effect and molecular mechanism of calycosin, the main active ingredient of Qinshi Simiao San, which can alleviate chronic prostatitis (CP), on CP remain unclear. This study aimed to elucidate the potential mechanism of action of calycosin in CP in a rat CP model. The prostate tissue morphology was evaluated based on hematoxylin–eosin staining. Enzyme-linked immunosorbent assay was conducted to evaluate inflammatory cytokine and immune factor levels (secretory immunoglobulin A [SIgA]; immunoglobulin G [IgG]) in prostate tissues and serum. Additionally, representative biomarkers of oxidative stress, including malondialdehyde, superoxide dismutase, and catalase were detected using detection kits, and reactive oxygen species release was evaluated using immunofluorescence staining. Furthermore, the p38 mitogen-activated protein kinase (p38MAPK)/NF-kappaB (NF-κB) signaling pathway was analyzed by western blotting. The results showed that calycosin substantially ameliorated the pathological damage to prostate tissues of the CP rats. Moreover, calycosin significantly downregulated interleukin (IL)-1β, IL-6, and tumor necrosis factor-alpha, IgG, and SIgA levels. Furthermore, we found that calycosin considerably suppressed oxidative stress and inhibited the activation of the p38MAPK/NF-κB signaling pathway in rats with CP. In summary, our findings revealed that calycosin protects against CP in rats by inhibiting the p38MAPK/NF-κB pathway.

Published
2023
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9. Changes of Channel Conditions of Zhangjiazhou Waterway for the 2020 Hydrological Year and Maintenance Countermeasures

Author

Xu, Hui, Shang, Qianqian, Xu, Xiangjun, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Li, Yun, editor, Hu, Yaan, editor, Rigo, Philippe, editor, Lefler, Francisco Esteban, editor, and Zhao, Gensheng, editor

Published
2023
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15. Emotional Computing Technology Applications in Information Systems Security and Their Risk Prevention

Author

Huang Gaofeng and Xu Xiangjun

Subjects
emotion vector, vector space model, emotion recognition method, information system security, risk index, 03d32, Mathematics, QA1-939
Abstract

This paper applies the emotion extraction method based on emotion lexicon to the group emotion analysis of the information system, combines the vector space model to process the text emotion in the information system, expresses the emotion in the form of vectors, and divides the different types of emotion according to the distance between the emotion vectors for identification. The five-level index system in fuzzy mathematics is chosen to measure the value of emotional intensity, and by analyzing the emotional state of the group in the information leakage incident, a decision in line with the user’s emotion is made based on the emotion of the information system security. Accordingly, the security defense index of the information system is improved according to the information security risk index. The results show that in identifying the emotions of the information system security events, the group’s emotions are mainly biased towards the negative. The proportion of negative emotions is the largest of 98%, which indicates that attention should be paid to the confidentiality of the user group’s information in the security of the information system. The maximum security event risk value in the evaluation in the information system is in the T8 period, with a value of 0.819, indicating that the security defense of the information system should be strengthened in the T8 period.

Published
2024
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25. Full-Stokes polarization laser-induced breakdown spectroscopy detection of infiltrative glioma boundary tissue

Author

Teng, Geer, primary, Wang, Qianqian, additional, Hao, Qun, additional, Fan, Axin, additional, Yang, Haifeng, additional, Xu, Xiangjun, additional, Chen, Guoyan, additional, Wei, Kai, additional, Zhao, Zhifang, additional, Khan, M. Nouman, additional, Idrees, Bushra Sana, additional, Bao, Mengyu, additional, Luo, Tianzhong, additional, Zheng, Yongyue, additional, and Lu, Bingheng, additional

Published
2023
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42. Prognosis of Ischemic Stroke Patients Undergoing Endovascular Thrombectomy is Influenced by Systemic Inflammatory Index Through Malignant Brain Edema

Author

Ji,Yachen, Xu,Xiangjun, Wu,Kangfei, Sun,Yi, Wang,Hao, Guo,Yapeng, Yang,Ke, Xu,Junfeng, Yang,Qian, Huang,Xianjun, Zhou,Zhiming, Ji,Yachen, Xu,Xiangjun, Wu,Kangfei, Sun,Yi, Wang,Hao, Guo,Yapeng, Yang,Ke, Xu,Junfeng, Yang,Qian, Huang,Xianjun, and Zhou,Zhiming

Abstract

Yachen Ji,* Xiangjun Xu,* Kangfei Wu, Yi Sun, Hao Wang, Yapeng Guo, Ke Yang, Junfeng Xu, Qian Yang, Xianjun Huang, Zhiming Zhou Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xianjun Huang; Zhiming Zhou, Department of Neurology, The First Affiliated Hospital of Wannan Medical College, 2# East Zheshan Road, Wuhu, 241000, People’s Republic of China, Tel +86-25-80860124, Fax +86-25-84664563, Email doctorhuangxj@hotmail.Com; neuro_depar@hotmail.ComPurpose: The systemic immune inflammatory index (SII), as a new marker, is widely used to predict the disease prognosis. We investigated the predictive value of SII for malignant cerebral edema (MCE) and whether postoperative MCE mediates the relationship between SII and functional prognosis in patients undergoing endovascular thrombectomy (EVT).Patients and Methods: A total of 829 patients with anterior circulation large-vessel occlusive stroke (LVOS) were registered, and 675 (81.4%) met the inclusion criteria. We collected baseline data upon admission, including SII. Postoperative computed tomography was performed to assess the presence and grading of cerebral edema (CED), and MCE was defined as a CED score of 3. A good prognosis was defined as a modified Rankin Scale (mRS) score of 0– 2 at the 90-day follow-up.Results: A total of 132 patients developed MCE after EVT. The patients were divided into MCE and non-MCE groups, and univariate and multifactorial analyses were performed. Among these risk factors, an elevated SII was independently correlated with the occurrence of MCE. In addition, the receiver operating characteristic (ROC) curve was used to assess the predictive capability of SII levels for prognosis. The area under the ROC was 0.69, and the optimal critical value was 2.14. In addition, postoperative MCE may partially account for the poorer functional progno

Published
2022

43. Fasting Blood-Glucose Level and Clinical Outcome in Anterior Circulation Ischemic Stroke of Different Age Groups After Endovascular Treatment

Author

Yuan,Lili, Sun,Yi, Huang,Xianjun, Xu,Xiangjun, Xu,Junfeng, Xu,Youqing, Yang,Qian, Zhu,Yujuan, Zhou,Zhiming, Yuan,Lili, Sun,Yi, Huang,Xianjun, Xu,Xiangjun, Xu,Junfeng, Xu,Youqing, Yang,Qian, Zhu,Yujuan, and Zhou,Zhiming

Abstract

Lili Yuan,&ast; Yi Sun,&ast; Xianjun Huang, Xiangjun Xu, Junfeng Xu, Youqing Xu, Qian Yang, Yujuan Zhu, Zhiming Zhou Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yujuan Zhu; Zhiming Zhou, Department of Neurology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui Province, 241000, People’s Republic of China, Email ajuan3975@163.com; neuro_depar@hotmail.comObjective: We aimed to analyze the association between fasting blood-glucose (FBG) level and 3-month functional outcome in anterior circulation ischemic stroke in different age groups after endovascular treatment (EVT).Methods: We retrospectively analyzed the consecutive patients with acute ischemic stroke (AIS) receiving EVT from our department between July 2015 and March 2021. The patients were categorized into the older (≥ 60 years) and younger (< 60 years) groups, and patients in each age group were dichotomized into favorable versus unfavorable outcomes according to the 3-month modified Rankin Scale (mRS) score.Results: A total of 504 patients (286 males and 218 females) were included in our study. Three hundred ninety-two patients (77.8%) belonged to the group aged ≥ 60 years, and 112 (22.2%) belonged to the group aged < 60 years. At the end of the study, 222 (56.6%) patients developed unfavorable outcomes in the older group and 31 (27.7%) showed unfavorable outcomes in the younger group. FBG level of the younger patients was significantly lower than that of older patients. In the older group, FBG level independently predicted a 3-month clinical unfavorable outcome with an odds ratio of 1.242 (95% confidence interval, 1.096– 1.407; p = 0.001). However, the association was not found in the younger group (p = 0.376).Conclusion: Higher FBG level is an independent risk factor for 3-month unfavorable outcome in the AIS

Published
2022

47. Optimization of supercritical CO2 extraction by response surface methodology, composition analysis and economic evaluation of bamboo green wax

Author

Tang Xinyuan, Xu Xiangjun, Guan Mingjie, and Yujia Li

Subjects
Wax, Bamboo, Supercritical carbon dioxide, Materials science, Renewable Energy, Sustainability and the Environment, Strategy and Management, Extraction (chemistry), Building and Construction, Pulp and paper industry, Environmentally friendly, Industrial and Manufacturing Engineering, Green waste, Differential scanning calorimetry, visual_art, visual_art.visual_art_medium, Response surface methodology, General Environmental Science
Abstract

Bamboo processing is faced with increasing requirements of resource reusability in China. A large amount of waste bamboo green produced in bamboo processing needs to be recycled. Waste bamboo green contains a large number of environmentally friendly wax components. In this study, supercritical CO2 extraction was used to extract bamboo green waste to obtain natural wax. Response surface methodology (RSM) was used to optimize the extraction process and the yield of bamboo green wax under pressure of 20–30 MPa, temperature of 318–328 K, and time of 30–90 min. The extracted bamboo green wax was characterized by gas chromatography and mass spectrometry (GC-MS). RSM optimization shows that under the conditions of 26 MPa, 328 K, and 56 min, the yield of bamboo green wax was the highest at 2.327%. The compositions of esters, fatty acids, sterols and so on in bamboo green wax were characterized by GC-MS. Differential scanning calorimetry (DSC) shows that the melting point of bamboo green wax is 334 K. At last, the economic evaluation of bamboo green wax was made to analyze its potential application prospect. It is supposed that bamboo green waste is a resource for natural wax with potential application value.

Published
2022
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48. The ACORNS grading scale: a novel tool for the prediction of malignant brain edema after endovascular thrombectomy

Author

Huang, Xianjun, Chen, Chu, Wang, Huaiming, Cai, Qiankun, Li, Zibao, Xu, Junfeng, Yuan, Lili, Xu, Xiangjun, Yang, Qian, Zhou, Zhiming, and Liu, Xinfeng

Abstract

BackgroundTo develop and validate a novel tool for predicting the development of malignant brain edema (MBE) in large vessel occlusion stroke patients after endovascular thrombectomy (EVT).MethodsWe used a prospectively registered population of EVT patients from three comprehensive stroke centers. The population was randomly divided into two subsets (7:3): a training cohort and an internal validation cohort. External validation was performed using the Endovascular Treatment for Acute Anterior Circulation Ischemic Stroke Registry in China (ACTUAL) database. MBE was defined as (1) hypodense parenchyma in at least 50% of the middle cerebral artery and signs of local brain swelling, and (2) a midline shift of ≥5 mm at the septum pellucidum or pineal gland with obliteration of the basal cisterns. The model was constructed using logistic regression analysis. The performance of the model was examined in terms of discrimination and calibration.ResultsAfter adjusting for other confounders, baseline National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT (ASPECT) scores, a clinical history of hypertension, collateral status, intravenous thrombolysis before thrombectomy, fasting blood glucose, reperfusion status, and occlusion site were found to be independent predictors of MBE. These variables were combined to create the ACORNS grading scale. The areas under the curve in receiver operating curve analysis were 0.850 (95% CI 0.816 to 0.884), 0.874 (95% CI 0.821 to 0.926), and 0.785 (95% CI 0.740 to 0.829) for the training, internal validation, and external validation cohorts, respectively, indicating good discriminative performance in the validation cohorts.ConclusionsThe ACORNS grading scale is an accurate and easily applicable model for the prediction of the development of MBE after EVT.

Published
2023
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49. Constructing a Large Language Model to Generate Impressions from Findings in Radiology Reports

Author

Zhang, Lu, Liu, Mingqian, Wang, Lingyun, Zhang, Yaping, Xu, Xiangjun, Pan, Zhijun, Feng, Yan, Zhao, Jue, Zhang, Lin, Yao, Gehong, Chen, Xu, and Xie, Xueqian

Abstract

A developed large language model generated radiologic impressions from findings in radiology reports that are professionally and linguistically appropriate for a full spectrum of radiology examinations.

Published
2024
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