451 results on '"Xiang Fu"'
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2. Multimodal human-machine collaborative control system for hydraulic supports following the shearer in the middle range of fully mechanized mining face
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Xiang FU, Haojie LI, Jintao ZHANG, Ranfeng WANG, Hongwei WANG, and Yifan QIN
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hydraulic supports ,man-machine cooperation ,multimodal ,ai enable ,cloud edge architecture ,Geology ,QE1-996.5 ,Mining engineering. Metallurgy ,TN1-997 - Abstract
The construction of intelligent fully mechanized mining faces in China’s coal mines is in its early stages, and the automation technology of hydraulic support electro-hydraulic control has been widely applied. However, at present, the automation control logic of a single solidification of hydraulic supports is difficult to adapt to complex, ever-changing, and dynamic production scenarios. The actual control process in mine face still mostly adopts a collaborative approach of automation and manual intervention. In response to the demand for human-machine interaction and cooperation tasks in the complex scenarios of fully mechanized mining faces, a theoretical method and technical principle of a multimodal human-machine collaborative control system for hydraulic supports following the shearer in the middle range mining face (hereinafter referred to as hydraulic supports following) was proposed. Firstly, four human-machine collaborative modes, namely manual, division of labor, approval, and veto, were designed. Based on the factors such as coal seam geology, gas and dust, shearer speed, hydraulic support intelligence level, system status, job technical level, and task load, an AND-OR graph model for hydraulic support human-machine collaborative mode selection was constructed, which achieved a modal selection with manual or machine preferences. Then, a human-machine collaborative control decision-making mechanism for hydraulic supports following was designed. On this basis, an AI inference technology for the secondary control strategy of hydraulic supports following was proposed. Specifically, using on-site data to learn manual operation experience, a decision tree classification model for whether the hydraulic support should be secondary controlled and a Bayesian regression model for estimating the secondary control time of pulling hydraulic support were constructed. Based on the above model, a human-machine collaborative control decision-making program for the hydraulic support following was developed, which achieved human-machine collaborative control of hydraulic supports following based on AND/OR inference for modal selection and AI inference for secondary control strategy. Finally, using cloud edge end architecture software and hardware technology, a multimodal human-machine collaborative control system for hydraulic supports following was developed, which achieved the control functions such as model evolution, operational reasoning, and program execution. The system has undergone industrial trial operation on the 3404 mining face of Shaqu No.2 Mine. The result shows the efficiency of the hydraulic support following has increased by an average of 2% compared to that before. This paper forms an efficient and safe human-machine interactive decision-making mechanism for the comprehensive mining equipment group, which will provide practical theoretical methods and feasible technical paths for the development of intelligent comprehensive mining working faces.
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- 2024
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3. Influence of magma intrusion on coal geochemical characteristics: a case study of Tiefa Daxing coal mine
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Xiang Fu, Xuan Liu, Qixuan Wu, Bin Xiao, and Chaojun Fan
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Medicine ,Science - Abstract
Abstract Magma intrusion has an important influence on the physical and mechanical properties of coal and rock. In the area of magma intrusion, disasters such as gas outburst are prone to occur. Revealing its invasion law will be conducive to disaster management and energy development. For this purpose, changes in industrial analysis components of coal, mineral composition, major oxides, trace elements, and rare earth elements of coal under the thermal metamorphism of magma intrusion were analyzed. It is found that the moisture and volatile matter contents of the thermally affected coals in the mining face are generally lower than that of normal coals, while moisture and volatile matter contents are reduced towards to the magma intrusion contact. For example, the moisture and volatile matter of coal sample M01 decreased by 64.6% and 38.6% respectively compared with coal sample M05. During magma intrusion, some minerals remain on the surface of the coal body, resulting in changes in the mineral composition of the coal body. The decrease in carbon atom net spacing, the increase in crystallite aggregation and ductility, and aromaticity in thermally affected coals have a positive impact on the improvement of coal metamorphism. Due to the influences of magmatic intrusion, the variation rules of major oxides in coal are different, and the closer to the magmatic intrusion zone, the easier the major oxides are to be depleted. However, magma intrusion will not lead to the loss of all major oxides in thermally affected coals, such as content of CaO is 54.8%, which is higher than that of coal not affected by magmatic hydrothermal fluid. Most of the trace elements in the thermally affected coals of the No. 9 coal seam are depleted. The contents of rare earth elements are low on the whole coalbasis, with an average of 29.48 μg/g, and the distribution pattern towards to magmatic intrusion shows a wide and gentle “V” curve with left high and right low, showing the characteristics of enrichment of light rare earth elements.
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- 2024
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4. Thickness ranges calculation method of double asphalt overlay on concrete pavement
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Xiang Fu, Jiayu Huang, Yuxin Ban, Jun Duan, and Jianuo Xie
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Asphalt overlay ,Thickness ,Shear stress ,Mohr–Coulomb criterion ,Tack coat ,Medicine ,Science - Abstract
Abstract Asphalt overlay is widely used in maintaining and rehabilitating highway system performance. However, explicit calculation methods for the asphalt overlay thickness range is lacking. Taking stone mastic asphalt (SMA) and asphalt concrete (AC) asphalt overlay on cement concrete pavement as examples, the paper proposed a design method for the asphalt overlay thickness range based on the shear performance of the interlayer. Firstly, the shear stress distribution regularities on the asphalt overlay and Portland cement concrete interlayer was calculated with a multilayer elastic theory. Meanwhile, the shear strength was obtained from a series of direct shear tests. The shear characters of the asphalt overlay met with the Mohr–Coulomb criterion, and the shear strength parameters cohesive force $$c$$ c and interface friction angle $$\varphi$$ φ on the interlayer were acquired. Finally, a method for determining the thickness range of double layer asphalt overlay under different traffic conditions was given. The epoxy resin adhesive was recommended for the highway with severe local premature shear failure compared with the modified emulsion asphalt. Therefore, through the above research, the amount of asphalt used is controlled in a reasonable range, thus improving the pavement structure durability and reducing energy consumption.
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- 2024
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5. Characterization of Coal Particle Methane Desorption and Optimization of Desorption Model Based on Desorption Damage
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Xiang Fu, Xuan Liu, Qixuan Wu, Teng Chang, and Yifan Wang
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Chemistry ,QD1-999 - Published
- 2024
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6. Rare Earth Element Characteristics of Shales from Wufeng–Longmaxi Formations in Deep-Buried Areas of the Northern Sichuan Basin, Southern China: Implications for Provenance, Depositional Conditions, and Paleoclimate
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Bin Xiao, Dongxu Guo, Sheng Li, Shuzhen Xiong, Zhaoyi Jing, Mingfei Feng, Xiang Fu, and Zhonghai Zhao
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Chemistry ,QD1-999 - Published
- 2024
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7. Regulatory role of Mycobacterium tuberculosis MtrA on dormancy/resuscitation revealed by a novel target gene-mining strategy
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Xiang Fu, Xiaoyu Wan, Aadil Ahmed Memon, Xiao-Yong Fan, Qiuhong Sun, Haifeng Chen, Yufeng Yao, Zixin Deng, Jian Ma, and Wei Ma
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Mycobacterium tuberculosis ,MtrA ,regulatory network ,dormancy ,resuscitation ,persistence ,Microbiology ,QR1-502 - Abstract
IntroductionThe unique dormancy of Mycobacterium tuberculosis plays a significant role in the major clinical treatment challenge of tuberculosis, such as its long treatment cycle, antibiotic resistance, immune escape, and high latent infection rate.MethodsTo determine the function of MtrA, the only essential response regulator, one strategy was developed to establish its regulatory network according to high-quality genome-wide binding sites.Results and discussionThe complex modulation mechanisms were implied by the strong bias distribution of MtrA binding sites in the noncoding regions, and 32.7% of the binding sites were located inside the target genes. The functions of 288 potential MtrA target genes predicted according to 294 confirmed binding sites were highly diverse, and DNA replication and damage repair, lipid metabolism, cell wall component biosynthesis, cell wall assembly, and cell division were the predominant pathways. Among the 53 pathways shared between dormancy/resuscitation and persistence, which accounted for 81.5% and 93.0% of the total number of pathways, respectively, MtrA regulatory genes were identified not only in 73.6% of their mutual pathways, but also in 75.4% of the pathways related to dormancy/resuscitation and persistence respectively. These results suggested the pivotal roles of MtrA in regulating dormancy/resuscitation and the apparent relationship between dormancy/resuscitation and persistence. Furthermore, the finding that 32.6% of the MtrA regulons were essential in vivo and/or in vitro for M. tuberculosis provided new insight into its indispensability. The findings mentioned above indicated that MtrA is a novel promising therapeutic target for tuberculosis treatment since the crucial function of MtrA may be a point of weakness for M. tuberculosis.
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- 2024
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8. Application of deep learning classification model for regional evaluation of roof pressure support evolution effects over time in coal mining face
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Hao-jie Li, Xiang Fu, Yi-fan Qin, and Si-feng Jia
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Smart mining face ,Leg pressure ,Spatio-temporal support quality ,Convolutional neural network ,Improved LeNet-5 network ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
Hydraulic support leg pressure serves as a crucial indicator for assessing work face support quality. Current evaluation methods for support quality primarily concentrate on static analyses-like inadequate initial support force, pressure overrun, and uneven bracket force-while neglecting dynamic column pressure changes. This paper introduces a model for assessing hydraulic support quality using deep learning techniques. Real-time data is preprocessed into a spatio-temporal pressure sub-matrix sample, which is then inputted into the model. This process assesses the support quality type and characterizes its dynamic evolution within the area. The model facilitates the identification of dynamic support quality effects in the working face area, aiding operators in making targeted adjustments to hydraulic support status. Experimental results revealed that the optimized LeNet-5 network-adjusting parameters like convolutional layer count, kernel size, and ReLU activation function-achieved the highest classification accuracy of 85.25 % for support quality, surpassed other networks. Furthermore, the improved LeNet-5 network outperformed other networks in both F1 score and recall. Additionally, the improved LeNet-5 network achieved faster convergence to the optimal solution, accelerated training speed. This highlighted its advantages in evaluating the spatio-temporal support quality of hydraulic supports in smart mining operations.
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- 2024
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9. Study on coal pulverization characteristics and gas desorption mechanism based on impact crushing experiment
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Xiang Fu, Qixuan Wu, Xuan Liu, Yifan Wang, and Teng Chang
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Coal and gas outburst ,Impact crushing ,Coal powdering ,Particle size distribution ,Gas desorption ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
The coal's particle size distribution properties after pulverization and the gas desorption behavior driven by pulverization are of profound meaning to the study of coal and gas outburst mechanism. In this paper, based on the impact crushing experiment, the tectonic coal and primary coal are crushed under different impact energy conditions. After screening the broken coal, the particle size distribution law is analyzed, and the characterization function suitable for the particle size distribution of coal particles after crushing is determined. The relationship between crushing work and new surface area and fractal dimension of coal body is discussed. The consequences indicated that the mass proportion of tectonic coal below 0.074 mm particle size is much huger than that of raw coal. G-S, R–R, and fractal distribution model describe the best particle size distribution of the two coals in the scope of 0.074∼4 mm. The new surface area added increases with the crushing work, and the tectonic coal is 1.34–1.96 times that of the raw coal. The fractal dimension diminishes first and then increases with the crushing work ratio. In addition, the gas desorption amount of coal particles with different particle sizes after coal pulverization was measured, and a dynamic model suitable for coal pulverization-driven gas desorption was established, and the experimental results were verified. The research results of this paper can provide experimental and theoretical basis for the analysis of energy dissipation in coal and gas outburst.
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- 2024
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10. Relationship between age and remimazolam dose required for inducing loss of consciousness in older surgical patients
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Jin-Chao Song, Xiao-xi Wang, Xiang Fu, Wei Chen, Shu-heng Tang, Fang Deng, Hua Yang, and Wen Liu
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older surgical patients ,remimazolam ,loss of consciousness ,anaesthetics ,intravenous anesthesia ,Medicine (General) ,R5-920 - Abstract
BackgroundRemimazolam is a new ultra-short-acting benzodiazepine for procedural sedation and general anaesthesia, characterised by rapid onset of action, quick recovery, and organ-independent metabolism. Older patients tend to sustain more treatment-emergent adverse events (TEAEs) and worse perioperative prognoses after receiving remimazolam. However, few studies have investigated the appropriate dose of remimazolam for loss of consciousness (LOC) in geriatric patients. We designed this study to provide evidence for dose references and elucidate the relationship between age and remimazolam requirement for inducing LOC during anaesthesia induction.MethodsExactly 120 patients scheduled for general surgery under general anaesthesia were included and divided into two groups: Group A (60 patients, 18–64 years) and Group B (60 patients, ≥ 65 years). LOC, defined as a Modified Observer’s Assessment of Alertness and Sedation score at 1 had been reached, emerged after all participants received a continuous infusion of remimazolam at a rate of 0.05 mg/kg/min.ResultsThe remimazolam required for inducing LOC was 0.26 and 0.19 mg/kg in groups A and B, respectively, and the remimazolam dose in group B decreased by 26.9% compared to group A. According to the bivariate linear correlation analysis, remimazolam requirement was negatively correlated with age. Multivariable linear regression models and further adjustments for potential impact factors indicated that age was an independent factor for the remimazolam dose required for LOC.ConclusionThis study demonstrated that age was significantly and independently correlated with the remimazolam requirement for inducing LOC. To obtain haemodynamic stability during the induction of general anaesthesia, appropriately reducing the remimazolam dose is recommended for geriatric patients.
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- 2024
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11. Elimination mechanism of coal and gas outburst based on geo-dynamic system with stress–damage–seepage interactions
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Lingjin Xu, Chaojun Fan, Mingkun Luo, Sheng Li, Jun Han, Xiang Fu, and Bin Xiao
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Coal and gas outburst ,Geo-dynamic system ,Stress–damage–seepage coupling ,Elimination mechanism ,Instability criterion ,Gas extraction ,Mining engineering. Metallurgy ,TN1-997 - Abstract
Abstract Coal and gas outburst is a complex dynamic disaster during coal underground mining. Revealing the disaster mechanism is of great significance for accurate prediction and prevention of coal and gas outburst. The geo-dynamic system of coal and gas outburst is proposed. The framework of geo-dynamic system is composed of gassy coal mass, geological dynamic environment and mining disturbance. Equations of stress–damage–seepage interaction for gassy coal mass is constructed to resolve the outburst elimination process by gas extraction with boreholes through layer in floor roadway. The results show the occurrence of outburst is divided into the evolution process of gestation, formation, development and termination of geo-dynamic system. The scale range of outburst occurrence is determined, which provides a spatial basis for the prevention and control of outburst. The formation criterion and instability criterion of coal and gas outburst are established. The formation criterion F 1 is defined as the scale of the geo-dynamic system, and the instability criterion F 2 is defined as the scale of the outburst geo-body. According to the geo-dynamic system, the elimination mechanism of coal and gas outburst—‘unloading + depressurization’ is established, and the gas extraction by boreholes through layer in floor roadway for outburst elimination is given. For the research case, when the gas extraction is 120 days, the gas pressure of the coal seam is reduced to below 0.4 MPa, and the outburst danger is eliminated effectively.
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- 2023
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12. Untargeted Metabolomics Analysis of Lactic Acid Bacteria Fermented Acanthopanax senticosus with Regard to Regulated Gut Microbiota in Mice
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Yuanyuan Su, Xiang Fu, and Pengwei Zhuang
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lactic acid bacteria ,fermentation ,Acanthopanax senticosus ,microbiota ,Organic chemistry ,QD241-441 - Abstract
Previous studies have shown that Acanthopanax senticosus (AS) has a beneficial preventive and therapeutic effect on colitis. The fermentation of lactic acid bacteria (LAB) can alter the efficacy of AS by modifying or producing new compounds with potential bioactive properties. However, the specific components and mechanisms that enhance the efficacy are still unclear. In the present experiment, untargeted metabolomics was used to analyze the changes in active components before and after LAB fermentation of AS. The aim was to explain the mechanism of AS fermentation in treating colitis using a colitis model in mice. The results indicated that the fermentation of LAB could enhance the levels of total flavonoids and total polyphenols in FAS. Additionally, the beneficial components such as Delphinidin chloride, Diosmetin, Psoralidin, and Catechol significantly increased (p < 0.05). The colitis treatment experiment demonstrated that fermented AS could alleviate symptoms and improve the morphology of colitis in mice by enhancing antioxidant enzymes like CAT, T-SOD, and T-AOC. It also regulated the composition and abundance of intestinal flora species, such as Lactobacillus and Pseudogracilibacillus. The effectiveness of fermented AS was significantly superior to that of unfermented AS (p < 0.05). In conclusion, this study contributes to the application of lactic acid bacteria in AS fermentation and reveals the mechanism of fermentation AS for colitis.
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- 2024
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13. A Study on the Influence of Anchor Rods’ Layout on the Uplift Resistance Characteristics of Inclined Anchor Short-Pile Foundations Based on FEA
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Yiran Gao, Yiqing Zhang, Qiang Xie, Quan Liu, Tinglei Liu, Ting You, Xiang Fu, Jun Duan, Peiyuan Qin, Tao Yang, and Yucheng Chen
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inclined anchor short-pile foundations ,FLAC3D ,uplift resistance characteristics ,anchor rod layout ,anchor rod position ,length of the free segment ,Building construction ,TH1-9745 - Abstract
In the steep terrain of southwestern China, there are numerous complex strata characterized by thin overburden layers and well-behaved underlying bedrock, yet excavation poses significant challenges. This situation is unfavorable for the construction of transmission towers’ foundations. To address this issue, inclined anchor short-pile foundations have been proposed as foundations for transmission towers. These foundations not only reduce the depth and construction difficulty of excavation but also make full use of the load-bearing capacity of the bedrock. To investigate the influence of the anchor rods’ layout on the uplift resistance characteristics of inclined anchor short-pile foundations, numerical models were established using FLAC3D. The effects of the anchor rods’ position and the length of the free segment on the uplift resistance characteristics of inclined anchor short-pile foundations were explored. The results indicated that variations in the anchor rods’ position and the length of the free segment had minimal impact on the uplift resistance characteristics of inclined anchor short-pile foundations. The pile head displacements of short piles with different anchor rod positions were similar under both loading conditions. Under pure uplift loads, the maximum displacement before failure was approximately 13 mm, while under combined uplift and horizontal loads, the maximum displacement before failure was around 15 mm. Placing the anchor rod too low increased the difficulty of construction, while positioning it too high resulted in a shorter embedment length of the anchor rod in the pile’s body, leading to potential failure at the pile–anchor node. Therefore, it is recommended to position the anchor rod near the center of the short pile’s body. As the length of the free segment of the anchor rod decreased, there was a slight reduction in the displacement under the same uplift loading conditions, with an overall difference of less than 5%. However, if full-length anchoring was adopted, the anchor rod was prone to tensile shear failure. Compared with short-pile foundations of the same size, inclined anchor short-pile foundations demonstrated enhanced ultimate bearing capacity under uplift and combined uplift and horizontal loading. The improvement was more significant when horizontal loads were present. Under horizontal loading, the ultimate uplift bearing capacity of inclined anchor short-pile foundations decreased by only 14%, whereas that of single-pile foundations decreased by 24%.
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- 2024
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14. Individual Deviation-Based Functional Hypergraph for Identifying Subtypes of Autism Spectrum Disorder
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Jialong Li, Weihao Zheng, Xiang Fu, Yu Zhang, Songyu Yang, Ying Wang, Zhe Zhang, Bin Hu, and Guojun Xu
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machine learning ,autism spectrum disorder ,heterogeneity ,diagnostic information ,individual deviation ,hypergraph community detection ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Heterogeneity has been one of the main barriers to understanding and treatment of autism spectrum disorder (ASD). Previous studies have identified several subtypes of ASD through unsupervised clustering analysis. However, most of them primarily depicted the pairwise similarity between individuals through second-order relationships, relying solely on patient data for their calculation. This leads to an underestimation of the complexity inherent in inter-individual relationships and the diagnostic information provided by typical development (TD). To address this, we utilized an elastic net model to construct an individual deviation-based hypergraph (ID-Hypergraph) based on functional MRI data. We then conducted a novel community detection clustering algorithm to the ID-Hypergraph, with the aim of identifying subtypes of ASD. By applying this framework to the Autism Brain Imaging Data Exchange repository data (discovery: 147/125, ASD/TD; replication: 134/132, ASD/TD), we identified four reproducible ASD subtypes with roughly similar patterns of ALFF between the discovery and replication datasets. Moreover, these subtypes significantly varied in communication domains. In addition, we achieved over 80% accuracy for the classification between these subtypes. Taken together, our study demonstrated the effectiveness of identifying subtypes of ASD through the ID-hypergraph, highlighting its potential in elucidating the heterogeneity of ASD and diagnosing ASD subtypes.
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- 2024
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15. Effect of Desorption Damage on the Kinetic Characteristics of Coal Particle Gas Desorption
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Xuan Liu, Xiang Fu, Bin Xiao, Donglei Cai, Lutian Zhao, Chengkai Yao, and Qixuan Wu
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Chemistry ,QD1-999 - Published
- 2023
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16. Mechanical properties and crack evolution characteristics of fractured rock with hidden fissures
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Yuxin Ban, Lihong Chen, Qiang Xie, Jun Duan, Chunbo He, Xiaoqiang Xue, and Xiang Fu
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Medicine ,Science - Abstract
Abstract Natural defects, such as joints, structural surfaces and voids, significantly affect the mechanical properties and fracture modes of rock mass. Hidden fissures are widely distributed in magmatic rock, while their influences on the mechanical properties and the cracking mechanism are still unclear. Laboratory tests were conducted on prefabricating hidden-fissured rock-like specimens, as well as intact specimens and close-fissured specimens as a comparison. The real-time digital image correlation technology and acoustic emission monitoring technology were synchronously adopted to capture both the external and internal cracking process. The results show that the hidden fissures can weaken the uniaxial compression strength, while the deterioration effect of hidden fissures is weaker than closed fissures due to the internal cohesion among fissure internal particles. What’s more, the initiation behavior of the α = 90° hidden-fissured specimen is different from that of β = 90° closed-fissured specimen. Finally, the cracking mechanism of hidden-fissured specimens was revealed by analyzing the RA–AF relationship. The failure of the close-fissured specimens is mainly the tensile-shear mixed fracture mode, while the failure of the hidden-fissured specimens is mainly the tensile fracture mode and supplemented by the shear. The experimental results contribute to the understanding of cracking properties in hidden-fissured rock.
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- 2023
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17. Hydrogen Jet Flame Simulation and Thermal Radiation Damage Estimation for Leakage Accidents in a Hydrogen Refueling Station
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Xiang Fu, Xianglin Yan, Shiyu Chen, Chunyan Song, Zhili Xiao, Hao Luo, Jiaqi Wan, Tianqi Yang, Nianfeng Xu, and Jinsheng Xiao
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hydrogen leakage ,jet flame ,simulation ,thermal radiation damage ,hydrogen refueling station ,Physics ,QC1-999 - Abstract
With the rapid development of hydrogen energy worldwide, the number of hydrogen energy facilities, such as hydrogen refueling stations, has grown rapidly in recent years. However, hydrogen is prone to leakage accidents during use, which could lead to hazards such as fires and explosions. Therefore, research on the safety of hydrogen energy facilities is crucial. In this paper, a study of high-pressure hydrogen jet flame accidents is conducted for a proposed integrated hydrogen production and refueling station in China. The effects of leakage direction and leakage port diameter on the jet flame characteristics are analyzed, and a risk assessment of the flame accident is conducted. The results showed that the death range perpendicular to the flame direction increased from 2.23 m to 5.5 m when the diameter of the leakage port increased from 4 mm to 10 mm. When the diameter of the leakage port is larger than 8 mm, the equipment on the scene will be within the boundaries of the damage. The consequences of fire can be effectively mitigated by a reasonable firewall setup to ensure the overall safety of the integrated station.
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- 2024
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18. Study on Liquid Hydrogen Leakage and Diffusion Behavior in a Hydrogen Production Station
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Xiang Fu, Guodong Li, Shiyu Chen, Chunyan Song, Zhili Xiao, Hao Luo, Jiaqi Wan, Tianqi Yang, Nianfeng Xu, and Jinsheng Xiao
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hydrogen safety ,liquid hydrogen ,leakage and diffusion ,flammable cloud ,computational fluid dynamics ,Physics ,QC1-999 - Abstract
Liquid hydrogen storage is an important way of hydrogen storage and transportation, which greatly improves the storage and transportation efficiency due to the high energy density but at the same time brings new safety hazards. In this study, the liquid hydrogen leakage in the storage area of a hydrogen production station is numerically simulated. The effects of ambient wind direction, wind speed, leakage mass flow rate, and the mass fraction of gas phase at the leakage port on the diffusion behavior of the liquid hydrogen leakage were investigated. The results show that the ambient wind direction directly determines the direction of liquid hydrogen leakage diffusion. The wind speed significantly affects the diffusion distance. When the wind speed is 6 m/s, the diffusion distance of the flammable hydrogen cloud reaches 40.08 m, which is 2.63 times that under windless conditions. The liquid hydrogen leakage mass flow rate and the mass fraction of the gas phase have a greater effect on the volume of the flammable hydrogen cloud. As the leakage mass flow rate increased from 5.15 kg/s to 10 kg/s, the flammable hydrogen cloud volume increased from 5734.31 m3 to 10,305.5 m3. The installation of a barrier wall in front of the leakage port can limit the horizontal diffusion of the flammable hydrogen cloud, elevate the diffusion height, and effectively reduce the volume of the flammable hydrogen cloud. This study can provide theoretical support for the construction and operation of hydrogen production stations.
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- 2024
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19. Synthetic Optimization of Trafficability and Roll Stability for Off-Road Vehicles Based on Wheel-Hub Drive Motors and Semi-Active Suspension
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Xiang Fu, Jiaqi Wan, Daoyuan Liu, Song Huang, Sen Wu, Zexuan Liu, Jijie Wang, Qianfeng Ruan, and Tianqi Yang
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off-road vehicle ,rollover stability ,slip-ratio control ,LuGre tire model ,model predictive control ,Mathematics ,QA1-939 - Abstract
Considering the requirements pertaining to the trafficability of off-road vehicles on rough roads, and since their roll stability deteriorates rapidly when turning violently or passing slant roads due to a high center of gravity (CG), an efficient anti-slip control (ASC) method with superior instantaneity and robustness, in conjunction with a rollover prevention algorithm, was proposed in this study. A nonlinear 14 DOF vehicle model was initially constructed in order to explain the dynamic coupling mechanism among the lateral motion, yaw motion and roll motion of vehicles. To acquire physical state changes and friction forces of the tires in real time, corrected LuGre tire models were utilized with the aid of resolvers and inertial sensors, and an adaptive sliding mode controller (ASMC) was designed to suppress each wheel’s slip ratio. In addition, a model predictive controller (MPC) was established to forecast rollover risk and roll moment in reaction to the change in the lateral forces as well as the different ground heights of the opposite wheels. During experimentation, the mutations of tire adhesion capacity were quickly discerned and the wheel-hub drive motors (WHDM) and ASC maintained the drive efficiency under different adhesion conditions. Finally, a hardware-in-the-loop (HIL) platform made up of the vehicle dynamic model in the dSPACE software, semi-active suspension (SAS), a vehicle control unit (VCU) and driver simulator was constructed, where the prediction and moving optimization of MPC was found to enhance roll stability effectively by reducing the length of roll arm when necessary.
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- 2024
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20. Research on Vehicle AEB Control Strategy Based on Safety Time–Safety Distance Fusion Algorithm
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Xiang Fu, Jiaqi Wan, Daibing Wu, Wei Jiang, Wang Ma, and Tianqi Yang
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automotive engineering ,Autonomous Emergency Braking control system ,safety distance algorithm ,optimized second–order Time to Collision safety time algorithm ,hierarchical braking control strategy ,Mathematics ,QA1-939 - Abstract
With the increasing consumer focus on automotive safety, Autonomous Emergency Braking (AEB) systems, recognized as effective active safety technologies for collision avoidance and the mitigation of collision-related injuries, are gaining wider application in the automotive industry. To address the issues of the insufficient working reliability of AEB systems and their unsatisfactory level of accordance with the psychological expectations of drivers, this study proposes an optimized second-order Time to Collision (TTC) safety time algorithm based on the motion state of the preceding vehicle. Additionally, the study introduces a safety distance algorithm derived from an analysis of the braking process of the main vehicle. The safety time algorithm focusing on comfort and the safety distance algorithm focusing on safety are effectively integrated in the time domain and the space domain to obtain the safety time–safety distance fusion algorithm. A MATLAB/Simulink–Carsim joint simulation platform has been established to validate the AEB control strategy in terms of safety, comfort, and system responsiveness. The simulation results show that the proposed safety time–safety distance fusion algorithm consistently achieves complete collision avoidance, indicating a higher safety level for the AEB system. Furthermore, the application of active hierarchical braking minimizes the distance error, at under 0.37 m, which meets psychological expectations of drivers and improves the comfort of the AEB system.
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- 2024
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21. Modeling Climate Characteristics of Qinghai Lake Ice in 1979–2017 by a Quasi-Steady Model
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Hong Tang, Yixin Zhao, Lijuan Wen, Matti Leppäranta, Ruijia Niu, and Xiang Fu
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Qinghai Lake ,lake ice ,ice thickness ,ice phenology ,quasi-steady model ,Science - Abstract
Lakes on the Qinghai Tibet Plateau (QTP) are widely distributed spatially, and they are mostly seasonally frozen. Due to global warming, the thickness and phenology of the lake ice has been changing, which profoundly affects the regional climate evolution. There are a few studies about lake ice in alpine regions, but the understanding of climatological characteristics of lake ice on the QTP is still limited. Based on a field experiment in the winter of 2022, the thermal conductivity of Qinghai Lake ice was determined as 1.64 W·m−1·°C−1. Airborne radar ice thickness data, meteorological observations, and remote sensing images were used to evaluate a quasi-steady ice model (Leppäranta model) performance of the lake. This is an analytic model of lake ice thickness and phenology. The long-term (1979–2017) ice history of the lake was simulated. The results showed that the modeled mean ice thickness was 0.35 m with a trend of −0.002 m·a−1, and the average freeze-up start (FUS) and break-up end (BUE) were 30 December and 5 April, respectively, which are close to the field and satellite observations. The simulated trend of the maximum ice thickness from 1979 to 2017 (0.004 m·a−1) was slightly higher than the observed result (0.003 m·a−1). The simulated trend was 0.20 d·a−1 for the FUS, −0.34 d·a−1 for the BUE, and −0.54 d·a−1 for the ice duration (ID). Correlation and detrending analysis were adopted for the contribution of meteorological factors. In the winters of 1979–2017, downward longwave radiation and air temperature were the two main factors that had the best correlation with lake ice thickness. In a detrending analysis, air temperature, downward longwave radiation, and solar radiation contributed the most to the average thickness variability, with contributions of 42%, 49%, and −48%, respectively, and to the maximum thickness variability, with contributions of 41%, 45%, and −48%, respectively. If the six meteorological factors (air temperature, downward longwave radiation, solar radiation, wind speed, pressure, and specific humidity) are detrending, ice thickness variability will increase 83% on average and 87% at maximum. Specific humidity, wind, and air pressure had a poor correlation with ice thickness. The findings in this study give insights into the long-term evolutionary trajectory of Qinghai Lake ice cover and serve as a point of reference for investigating other lakes in the QTP during cold seasons.
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- 2024
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22. Peripheral blood CD19 positive B lymphocytes increase after ischemic stroke and correlate with carotid atherosclerosis
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Yuhua Zhang, Yu Jiang, Yutian Zou, Yinyin Fan, Ping Feng, Xiang Fu, Keru Li, Jinru Zhang, Yunlei Dong, Shuying Yan, and Yanlin Zhang
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B lymphocytes ,CD19 ,lipid metabolism ,carotid atherosclerosis ,ischemic stroke ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
IntroductionAtherosclerosis is the primary pathological basis of ischemic stroke, and dyslipidemia is one of its major etiological factors. Acute ischemic stroke patients exhibit imbalances in lymphocyte subpopulations, yet the correlation between these dynamic changes in lymphocyte subpopulations and lipid metabolism disorders, as well as carotid atherosclerosis in stroke patients remains poorly understood.MethodsWe retrospectively analyzed the demographic data, risk factors of cerebrovascular disease, laboratory examination (lymphocyte subsets, lipid indexes, etc.), clinical features and c;/]-sity from December 2017 to September 2019 and non-stroke patients with dizziness/vertigo during the same period.ResultsThe results showed that peripheral B lymphocyte proportions are elevated in acute ischemic stroke patients compared with those of the control group (13.6 ± 5.3 vs. 11.7 ± 4.4%, p = 0.006). Higher B lymphocyte proportions are associated with concurrent dyslipidemia, increased levels of vascular risk factors including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and very-low-density lipoprotein cholesterol (VLDL-C), as well as decreased levels of the protective factor high-density lipoprotein cholesterol (HDL-C). Elevated B lymphocyte proportions are independently correlated with carotid atherosclerosis in stroke patients.DiscussionWe found CD19 positive B Lymphocytes increase after ischemic stroke and correlate with Carotid Atherosclerosis. Lymphocyte subpopulations should be highlighted in stroke patients.
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- 2023
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23. An asymmetric catalytic multi-component reaction enabled the green synthesis of isoserine derivatives and semi-synthesis of paclitaxel
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Taoda Shi, Xinglin Li, Yukai Li, Xiang Fu, Linna Wu, Dengqing Wu, and Wenhao Hu
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Asymmetric catalysis ,Multi-component reaction ,Green semi-synthesis ,Paclitaxel ,Chemical technology ,TP1-1185 ,Biochemistry ,QD415-436 - Abstract
Paclitaxel (Taxol@) as a cornerstone of chemotherapy remains in high demand. The semi-synthesis of paclitaxel via coupling of Taxus leaf-produced baccatin III and manually synthesized isoserine (C-13 side chain) is one of the solutions to avoid environmental damage caused by the sacrifice of the whole Taxus brevifolia. A green synthesis of the C-13 side chain is pivotal to the green production of paclitaxel. We herein report a green synthesis of isoserine derivatives and the semi-synthesis of paclitaxel via a straightforward assembly of isoserines based on an Rh2(TPA)3(OAc)/CPA1 co-catalyzed asymmetric multi-component reaction of ethyl diazoacetate, triethyl silanol and N-(anthrancen-9-ylmethyl)benzaldimine. The method is featured by improved atom economy, effective mass yield, and environmental factors compared to our previous racemic method and BMS company's semi-synthesis method. And the method allows for rapid access to paclitaxel derivatives with varied C-13 side chains.
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- 2023
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24. Multi-scale YOLACT for instance segmentation
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Jiexian Zeng, Huan Ouyang, Min Liu, LU Leng, and Xiang Fu
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Instance segmentation ,The response of prototype mask ,Multi-scale features ,Semantic information ,Detailed information ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
The mainstream instance segmentation is a comprehensive computer vision task, which involves computer vision tasks such as image classification, object detection, and semantic segmentation. Aiming at the Prototype mask for initial segmentation mask with incorrect segmentation, this paper uses YOLACT (You Only Look at CoefficienTs) as the benchmark, in order to improve the network performance in the interfernce situation by enhancing the response of prototype mask, the multi-scale YOLACT for instance segmentation (MS YOLACT) is proposed, which increases the accuracy of segmentation by designing a lightweight network structure. First, the image gets multi-scale features through the residual network and the feature pyramid network. Then, the deep up-sampling and shallow down-sampling in the multi-scale feature layer are realized respectively to the size required by the prototype mask branch input, and all the deep information that has been up-sampled is further learned by convolution. Finally, at the input end of the prototype mask branch, the deep information and the shallow information are sequentially merged in an additive manner to improve the response of the prototype mask, thereby improving the accuracy of the target's mask segmentation. The experimental results show that compared with the benchmark on COCO test-dev, when the speed is reduced by only 1 FPS, the overall segmentation accuracy reaches an improvement of 0.6, and the segmentation accuracy of small and large targets reaches an improvement of 0.4 and 0.7 respectively; the visualization results also show that the segmentation mask of MS YOLACT is more accurate. In addition, MS YOLACT has the advantages of higher speed and lower requirements on equipment.
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- 2022
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25. Substrate DNA Promoting Binding of Mycobacterium tuberculosis MtrA by Facilitating Dimerization and Interpretation of Affinity by Minor Groove Width
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Aadil Ahmed Memon, Xiang Fu, Xiao-Yong Fan, Lingyun Xu, Jihua Xiao, Mueed Ur Rahman, Xiaoqi Yang, Yu-Feng Yao, Zixin Deng, and Wei Ma
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Mycobacterium tuberculosis ,MtrA ,quantitative affinity ,minor groove width (MGW) ,dimerization ,Biology (General) ,QH301-705.5 - Abstract
In order to deepen the understanding of the role and regulation mechanisms of prokaryotic global transcription regulators in complex processes, including virulence, the associations between the affinity and binding sequences of Mycobacterium tuberculosis MtrA have been explored extensively. Analysis of MtrA 294 diversified 26 bp binding sequences revealed that the sequence similarity of fragments was not simply associated with affinity. The unique variation patterns of GC content and periodical and sequential fluctuation of affinity contribution curves were observed along the sequence in this study. Furthermore, docking analysis demonstrated that the structure of the dimer MtrA-DNA (high affinity) was generally consistent with other OmpR family members, while Arg 219 and Gly 220 of the wing domain interacted with the minor groove. The results of the binding box replacement experiment proved that box 2 was essential for binding, which implied the differential roles of the two boxes in the binding process. Furthermore, the results of the substitution of the nucleotide at the 20th and/or 21st positions indicated that the affinity was negatively associated with the value of minor groove width precisely at the 21st position. The dimerization of the unphosphorylated MtrA facilitated by a low-affinity DNA fragment was observed for the first time. However, the proportion of the dimer was associated with the affinity of substrate DNA, which further suggested that the affinity was actually one characteristic of the stability of dimers. Based on the finding of 17 inter-molecule hydrogen bonds identified in the interface of the MtrA dimer, including 8 symmetric complementary ones in the conserved α4-β5-α5 face, we propose that hydrogen bonds should be considered just as important as salt bridges and the hydrophobic patch in the dimerization. Our comprehensive study on a large number of binding fragments with quantitative affinity values provided new insight into the molecular mechanism of dimerization, binding specificity and affinity determination of MtrA and clues for solving the puzzle of how global transcription factors regulate a large quantity of target genes.
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- 2023
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26. Effect of Diatomite on Properties of Cement- Copper Tailing Powder Cementitious Materials
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Xiang Fu, Xianglan Li, Hui Guo, Xiaoying Peng, Fanghua Liu, and Shenglei Feng
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diatomite ,copper tailing powder ,portland cement ,cementitious material ,mechanical strength ,Mining engineering. Metallurgy ,TN1-997 - Abstract
To overcome the poor mechanical strength of copper tailing powders- Portland cement, diatomite was added into this cementitious system.Diatomite replaced the copper tailing powders- Portland cement with 0.5%, 1.0%, 1.5% and 2.0% in weight.The fluidity, setting time, water absorption, porosity, bulk density, mechanical properties and microscopic properties of the composite cement materials were tested. The results showed that with the increase of the dosage of diatomite, the fluidities of the pastes decrease, the setting time shortens, water absorptions and porosities decrease, bulk densities increase, compressive strength and flexural strength of the mortars increase. After curing for 28 days, the addition of diatomite makes the SiO2 and Ca(OH)2 content in the hydration products decrease, the C-S-H (Calcium Silicate Hydrate) gels increase, and the whole is denser.
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- 2022
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27. Micro-Porosity and gas emission characteristics of thermally contacted metamorphic coal by igneous intrusion
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Xiang Fu, Hongda Liu, Huihui Sha, Zhiquan Wang, and Xuan Liu
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initial velocity of gas emission ,coal and gas outburst ,thermally contacted metamorphic coal ,pore structure ,PCAS ,Science - Abstract
In order to quantitatively characterize the pore structure of thermally contacted metamorphic coal by igneous intrusion and investigate the intrinsic connection between the pore and dispersion properties of coal, the samples of metamorphic coal from different locations of Daxing Coal Mine were collected and processed. The correlative analysis on pore characteristics, including pore area, perimeter, shape factor and fractal dimension of pores with different sizes, were carried out by using scanning electron microscopy (SEM) and pore-fracture analysis system (PCAS). The results show that the porosity of macro- and meso-pores and the number of pores in the metamorphic coal are larger than those of the normal coal. The total length of pores per unit area and the average shape factor increase, and the connectivity of pore is raised, resulting in an enhanced gas release capacity (increased V1) within the first one second. The proportion of gas emission in the first one second of metamorphic coal is much higher than that of other coals. The decrease of pore volume and specific surface area of micropores makes the adsorption capacity weaker, which results in a decrease in the total amount of emission - smaller Δp value, and earlier inflection point and faster attenuation on the emission curve, namely an increased α value. In addition, the V1, α value and volatile content satisfy the quadratic nonlinear and linear relationships, respectively. In the prediction of outburst risk of thermally contacted metamorphic coal, it is more reasonable to use the V1 index to characterize the gas release rate.
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- 2023
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28. Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence
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Maxim Signaevsky, Bahram Marami, Marcel Prastawa, Nabil Tabish, Megan A. Iida, Xiang Fu Zhang, Mary Sawyer, Israel Duran, Daniel G. Koenigsberg, Clare H. Bryce, Lana M. Chahine, Brit Mollenhauer, Sherri Mosovsky, Lindsey Riley, Kuldip D. Dave, Jamie Eberling, Chris S. Coffey, Charles H. Adler, Geidy E. Serrano, Charles L. White, John Koll, Gerardo Fernandez, Jack Zeineh, Carlos Cordon-Cardo, Thomas G. Beach, and John F. Crary
- Subjects
Artificial intelligence ,Machine learning ,Deep learning ,Convolutional neural network ,Whole slide image ,Parkinson’s disease ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract The diagnosis of Parkinson’s disease (PD) is challenging at all stages due to variable symptomatology, comorbidities, and mimicking conditions. Postmortem assessment remains the gold standard for a definitive diagnosis. While it is well recognized that PD manifests pathologically in the central nervous system with aggregation of α-synuclein as Lewy bodies and neurites, similar Lewy-type synucleinopathy (LTS) is additionally found in the peripheral nervous system that may be useful as an antemortem biomarker. We have previously found that detection of LTS in submandibular gland (SMG) biopsies is sensitive and specific for advanced PD; however, the sensitivity is suboptimal especially for early-stage disease. Further, visual microscopic assessment of biopsies by a neuropathologist to identify LTS is impractical for large-scale adoption. Here, we trained and validated a convolutional neural network (CNN) for detection of LTS on 283 digital whole slide images (WSI) from 95 unique SMG biopsies. A total of 8,450 LTS and 35,066 background objects were annotated following an inter-rater reliability study with Fleiss Kappa = 0.72. We used transfer learning to train a CNN model to classify image patches (151 × 151 pixels at 20× magnification) with and without the presence of LTS objects. The trained CNN model showed the following performance on image patches: sensitivity: 0.99, specificity: 0.99, precision: 0.81, accuracy: 0.99, and F-1 score: 0.89. We further tested the trained network on 1230 naïve WSI from the same cohort of research subjects comprising 42 PD patients and 14 controls. Logistic regression models trained on features engineered from the CNN predictions on the WSI resulted in sensitivity: 0.71, specificity: 0.65, precision: 0.86, accuracy: 0.69, and F-1 score: 0.76 in predicting clinical PD status, and 0.64 accuracy in predicting PD stage, outperforming expert neuropathologist LTS density scoring in terms of sensitivity but not specificity. These findings demonstrate the practical utility of a CNN detector in screening for LTS, which can translate into a computational tool to facilitate the antemortem tissue-based diagnosis of PD in clinical settings.
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- 2022
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29. Experimental research on the spontaneous combustion of Yangquan coal induced by electrochemical oxidation of pyrite
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Xun Zhang, Bing Lu, Xiang Fu, Ling Qiao, Jiren Wang, Lijie Wang, Cong Ding, Dameng Gao, and Jing Zhang
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Medicine ,Science - Abstract
Abstract The 15# coal seam of Yangmei No.5 Mine, which produces anthracite, which is the least prone to spontaneous combustion, has a serious hidden danger of spontaneous combustion due to the high sulfur content in the coal. Based on the better conductivity of anthracite, we designed an electrolysis experiment to accelerate the electrochemical oxidation of pyrite in coal. Through experiments and analysis of thermodynamic characteristic parameters, it is obtained that the electrochemical oxidation of pyrite and its main products Fe3+ and Fe2+ have a coupled catalytic effect on the spontaneous combustion of high-sulfur coal in Yangquan. Combined with the FTIR test and analysis, it is found that the electrochemical process causes spatial polarization in the coal, so that polar groups such as –OH undergo spatial diversion and increase the activity. Due to the high content of –OH in Yangquan anthracite, the electrochemical process has the greatest effect on promoting –OH oxidation. Fe3+ and Fe2+ act as strong oxidants and free radicals to promote the –CH2– reaction to generate C=O and promote the generation of CO. This research provides a new direction for the exploration of the spontaneous combustion mechanism of high-sulfur anthracite.
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- 2022
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30. A Novel Program Suspend Scheme for Improving the Reliability of 3D NAND Flash Memory
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Zhichao Du, Zhipeng Dong, Kaikai You, Xinlei Jia, Ye Tian, Yu Wang, Zhaochun Yang, Xiang Fu, Fei Liu, Qi Wang, Lei Jin, and Zongliang Huo
- Subjects
3D NAND flash memory ,program suspend operation ,fail bit count ,grain boundary trap ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Experimental results indicate that the conventional program suspend scheme in 3D NAND flash memory chip can generate unexpected additional read fail bits and reduce the reliability of 3D NAND flash memory. These extra read fail bits are observed when the program suspend command is issued during the program stage, and particularly, they become more obvious as the delay time between program suspend operation and other following operations exceeds tens of milliseconds. By analyzing the waveform of conventional program suspend scheme, it is suggested that the unexpected extra read fail bits are caused by the different occupancy of grain boundary traps (GBTs) in the polycrystalline silicon (poly-Si) channel during the idle time after the program suspend operation. Accordingly, a novel program suspend scheme is proposed by adding a “stabilizing” pulse immediately after the program stage. Silicon experimental data show that the proposed scheme can effectively limit the read fail bit count (FBC) to a normal range, thus improving the reliability of 3D NAND flash memory significantly.
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- 2022
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31. The Pathogenicity of Fusobacterium nucleatum Modulated by Dietary Fibers—A Possible Missing Link between the Dietary Composition and the Risk of Colorectal Cancer
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Sadia Nawab, Qelger Bao, Lin-Hua Ji, Qian Luo, Xiang Fu, Shuxuan Fan, Zixin Deng, and Wei Ma
- Subjects
Fusobacterium nucleatum ,butyrate ,polydextrose ,fibersol-2 ,colorectal cancer ,dietary fibers ,Biology (General) ,QH301-705.5 - Abstract
The dietary composition has been approved to be strongly associated with the risk of colorectal cancer (CRC), one of the most serious malignancies worldwide, through regulating the gut microbiota structure, thereby influencing the homeostasis of colonic epithelial cells by producing carcinogens, i.e., ammonia or antitumor metabolites, like butyrate. Though butyrate-producing Fusobacterium nucleatum has been considered a potential tumor driver associated with chemotherapy resistance and poor prognosis in CRC, it was more frequently identified in the gut microbiota of healthy individuals rather than CRC tumor tissues. First, within the concentration range tested, the fermentation broth of F. nucleatum exhibited no significant effects on Caco-2 and NCM460 cells viability except for a notable up-regulation of the expression of TLR4 (30.70%, p < 0.0001) and Myc (47.67%, p = 0.021) and genes encoding proinflammatory cytokines including IL1B (197.57%, p < 0.0001), IL6 (1704.51%, p < 0.0001), and IL8 (897.05%, p < 0.0001) in Caco-2 cells exclusively. Although no marked effects of polydextrose or fibersol-2 on the growth of F. nucleatum, Caco-2 and NCM460 cells were observed, once culture media supplemented with polydextrose or fibersol-2, the corresponding fermentation broths of F. nucleatum significantly inhibited the growth of Caco-2 cells up to 48.90% (p = 0.0003, 72 h, 10%) and 52.96% (p = 0.0002, 72 h, 10%), respectively in a dose-dependent manner. These two kinds of fibers considerably promoted butyrate production of F. nucleatum up to 205.67% (p < 0.0001, 6% polydextrose at 24 h) and 153.46% (p = 0.0002, 6% fibersol-2 at 12 h), which explained why and how the fermentation broths of F. nucleatum cultured with fibers suppressing the growth of Caco-2 cells. Above findings indicated that dietary fiber determined F. nucleatum to be a carcinogenic or antitumor bacterium, and F. nucleatum played an important role in the association between the dietary composition, primarily the content of dietary fibers, and the risk of CRC.
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- 2023
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32. Exploring the intermittency of magnetohydrodynamic turbulence by synchrotron polarization radiation
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Wang, Ru-Yue, Zhang, Jian-Fu, Lu, Fang, and Xiang, Fu-Yuan
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Magnetohydrodynamic (MHD) turbulence plays a critical role in many key astrophysical processes such as star formation, acceleration of cosmic rays, and heat conduction. However, its properties are still poorly understood. We explore how to extract the intermittency of compressible MHD turbulence from the synthetic and real observations. The three statistical methods, namely the probability distribution function, kurtosis, and scaling exponent of the multi-order structure function, are used to reveal the intermittency of MHD turbulence. Our numerical results demonstrate that: (1) the synchrotron polarization intensity statistics can be used to probe the intermittency of magnetic turbulence, by which we can distinguish different turbulence regimes; (2) the intermittency of MHD turbulence is dominated by the slow mode in the sub-Alfv{\'e}nic turbulence regime; (3) the Galactic interstellar medium (ISM) at the low latitude region corresponds to the sub-Alfv\'enic and supersonic turbulence regime. We have successfully measured the intermittency of the Galactic ISM from the synthetic and realistic observations., Comment: 13 pages, 10 figures, 1 table. Accepted for publication in A&A
- Published
- 2024
33. Fast neutron irradiation effects on Si- and GaN-based avalanche photodiodes
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Xiang Fu, Biao Wei, Jianbin Kang, Wangping Wang, Ge Tang, Qian Li, Feiliang Chen, and Mo Li
- Subjects
Si ,GaN ,APDs ,Neutron irradiation ,Physics ,QC1-999 - Abstract
We report the behaviour of the dark current and gain characteristics of Si- and GaN-based avalanche photodiodes (APDs) irradiated by fast neutrons. For Si-based APDs, the dark current increases with the increase of neutron fluence, indicating that the avalanche property has been seriously affected. The gain values of Si-based APD slightly increase after irradiation by a low neutron fluence of 1.0 × 1012 cm−2, while the device exhibits gain degradation as the fluence increases to 1.0 × 1013 cm−2 or even above at high reverse bias voltage, unlike the previous studies where only degradation was observed. The steep increase of dark current and gain when approaching the breakdown voltage after neutron irradiation indicate that the avalanche property is almost unaffected for GaN-based APDs. Furthermore, we infer that the optical absorption between acceptor state and conduction band in the p-type layer plays an important role in influencing the change of dark current and gain at high reverse bias voltage. The findings not only enrich the understanding of neutron irradiation effect on Si- and GaN-based APDs, but also experimentally prove that GaN-based APDs hold better radiation resistance than Si-based devices.
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- 2022
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34. Flavonoids in Amomum tsaoko Crevost et Lemarie Ameliorate Loperamide-Induced Constipation in Mice by Regulating Gut Microbiota and Related Metabolites
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Yifan Hu, Xiaoyu Gao, Yan Zhao, Shuangfeng Liu, Kailian Luo, Xiang Fu, Jiayi Li, Jun Sheng, Yang Tian, and Yuanhong Fan
- Subjects
Amomum tsaoko ,constipation ,gut microbiota ,gut metabolites ,gastrointestinal motility ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Amomum tsaoko (AT) is a dietary botanical with laxative properties; however, the active ingredients and mechanisms are still unclear. The active fraction of AT aqueous extract (ATAE) for promoting defecation in slow transit constipation mice is the ethanol-soluble part (ATES). The total flavonoids of ATES (ATTF) were the main active component. ATTF significantly increased the abundance of Lactobacillus and Bacillus and reduced the dominant commensals, such as Lachnospiraceae, thereby changing the gut microbiota structure and composition. Meanwhile, ATTF changed the gut metabolites mainly enriched in pathways such as the serotonergic synapse. In addition, ATTF increased the serum serotonin (5-HT) content and mRNA expression of 5-hydroxytryptamine receptor 2A (5-HT2A), Phospholipase A2 (PLA2), and Cyclooxygenase-2 (COX2), which are involved in the serotonergic synaptic pathway. ATTF increased Transient receptor potential A1 (TRPA1), which promotes the release of 5-HT, and Myosin light chain 3(MLC3), which promotes smooth muscle motility. Notably, we established a network between gut microbiota, gut metabolites, and host parameters. The dominant gut microbiota Lactobacillus and Bacillus, prostaglandin J2 (PGJ2) and laxative phenotypes showed the most significant associations. The above results suggest that ATTF may relieve constipation by regulating the gut microbiota and serotonergic synaptic pathway and has great potential for laxative drug development in the future.
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- 2023
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35. Recent Advances and Challenges in the Inverse Identification of Thermal Diffusivity of Natural Ice in China
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Zhijun Li, Xiang Fu, Liqiong Shi, Wenfeng Huang, and Chunjiang Li
- Subjects
natural ice ,thermal diffusivity ,inversion identification ,vertical temperature profile ,research status ,Hydraulic engineering ,TC1-978 ,Water supply for domestic and industrial purposes ,TD201-500 - Abstract
The ice thermal parameters are the key to reasonably simulating ice phenology, distribution, and thickness, but they have always been a “vulnerable group” in ice research. Technically, it may seem simple to obtain accurate ice thermal property parameters, but in reality, there are numerous impact factors, requiring a rigorous research process. In the 1980s, the thermal conductivity of ice was explored in the field and laboratory, after which there has been no significant progress in China. In this century, mathematics is introduced, after which the inversion identification and analysis with the time-series data of the vertical temperature profiles of ice layers by in situ testing are carried out. The in situ thermal diffusivities of different natural ices were obtained and cross-validated with the inversion identification results. Both natural freshwater ice and sea ice exhibited differences in the thermal diffusivity of the pure ice chosen for the current simulations due to impurities within the unfrozen water among the ice crystals, but the trends are consistent with the results of a small number of laboratory tests on different types of saltwater frozen ice. In this paper, the inversion identification results of the thermal diffusivity of typical ice were selected, and the factors constraining the thermal diffusivities were analyzed. The importance of parameterizing the thermal diffusivity in the phase transition zone of ice under the trend of global warming was illustrated. Future research ideas on the physical mechanism, application value, and parameterization scheme of the thermal diffusivity of natural ice were envisaged.
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- 2023
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36. Investigation on Coal Skeleton Deformation in CO2 Injection Enhanced CH4 Drainage From Underground Coal Seam
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Chaojun Fan, Lei Yang, Gang Wang, Qiming Huang, Xiang Fu, and Haiou Wen
- Subjects
coal seam ,CO2 injection enhanced CH4 drainage ,coal skeleton deformation ,numerical simulation ,fluid-solid coupling model ,Science - Abstract
To reveal the evolution law of coal skeleton deformation during the process of CO2 flooding and displacing CH4 in coal seam, a fluid-solid coupling mathematical model of CO2 injection enhanced CH4 drainage was established based on Fick’s law, Darcy’s law, ideal gas state equation, and Langmuir equation. Meanwhile, numerical simulations were carried out by implementing the mathematical model in the COMSOL Multiphysics. Results show that the CH4 content of both regular gas drainage and CO2 enhanced gas drainage gradually decreases with time, and the decreasing rate is high between 10 and 60 days. Compared with regular gas drainage, the efficiency of CO2 enhanced gas drainage is more obvious with greater amount of CH4 extracted out. When coal seam gas is extracted for 10, 60, 120, and 180 days, CH4 content in coal seam is reduced by 5.2, 17.2, 23.6, and 26.7%, respectively. For regular gas drainage, the deformation of coal skeleton is dominated by the shrink of coal matrix induced by gas desorption, and the strain curve shows a continuous downward trend. For CO2 enhanced gas drainage, the strain curve of coal skeleton showed a decrease—rapid increase—slow increase trend. The evolution of permeability is opposite to the evolution of coal skeleton strain. Higher gas injection pressure will lead to a greater coal skeleton strain. The pumping pressure affects the deformation of coal skeleton slightly compared with that of initial water saturation and initial temperature. Greater initial water saturation leads to larger deformation of coal skeleton in the early stage. The strain value of coal skeleton gradually tends to be consistent as gas injection prolongs. Higher initial temperature leads to greater reduction in coal skeleton strain when the gas injection continues. Research achievements provide a basis for the field application of CO2 injection enhanced CH4 drainage in underground coal mines.
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- 2021
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37. Focus on the Avalanche Breakdown Characteristic of Si- and InP-Based APDs Irradiated by Fast Neutrons
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Jianbin Kang, Qian Li, Xiang Fu, Feiliang Chen, and Mo Li
- Subjects
avalanche breakdown ,fast neutron ,APD ,Mechanical engineering and machinery ,TJ1-1570 - Abstract
The Si- and InP-based APDs as the most important weak light semiconductor photodetectors to have achieved commercial success and are widely used in irradiation environments. Investigating the influencing mechanism of neutron irradiation on the above two types of APDs is of scientific and practical importance. In this paper, the dark current and gain characteristics of Si- and InP-based APDs around breakdown voltage were analyzed in detail before and after irradiation. The increase of dark current and the decrease of gain were observed for both the neutron irradiated Si- and InP-based APDs. Generation centers induced by neutrons are responsible for the increased dark current. The decrease of gain can be attributed to the increase of multiplied dark current and the change of electric field distribution in APD. The Si-based APD exhibits soft breakdown with the breakdown voltage reduced by ~8 V under the neutron fluence of 1.0 × 1012 cm−2, while the soft breakdown occurs along with a small change of breakdown voltage of ~1.5 V under the neutron fluence of 1.0 × 1013 cm−2 for InP-based APD. The difference in the change of breakdown voltage probably occurs because the Si-based APD uses p-doped Si as the multiplication layer, in which the neutron induced carrier removing effect cannot be ignored to keep the electric field distribution away from the optimal state. Therefore, using an intrinsic multiplication layer in APD is helpful to improve the neutron radiation resistance. The findings here are not only useful for the radiation hardened design of APD, but also deepen the understanding of irradiation mechanism.
- Published
- 2022
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38. Influences of Inclined Pre-Existing Flaw on Shale Failure Modes in Uniaxial Compression Tests
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Yuxin Ban, Qiang Xie, Jun Duan, and Xiang Fu
- Subjects
shale ,failure mode ,bedding layer ,pre-existing flaw ,acoustic emission ,moment tensor ,Mineralogy ,QE351-399.2 - Abstract
Numerous studies have focused on the mechanical properties of shale specimens to support hydraulic fracturing in shale gas engineering. However, the failure modes of shale specimens containing a pre-existing flaw are still not clear. A series of uniaxial compression tests were conducted on shale specimens containing a pre-existing flaw coupled with acoustic emission (AE) technology and a high-speed camera. A slow enough and variable loading speed scheme (0–50 kN: 0.1 kN/s, 50–100 kN: 0.05 kN/s; 100-failure: 0.02 kN/s) is adopted to allow microcracks to fully develop. The damage mechanism in the mesoscale from moment tensor inversion of the AE signals and the cracking behaviors on the macroscale were associated. Both the pre-existing flaw and the bedding layers had significant influences on the mechanical characteristics, progressive cracking, and failure modes of the shale specimens. The peak stress increases fluctuated as the bedding layer angle α increases, and the maximum and minimum values take place at α=90° and α=0°, respectively. In addition, the pre-existing flaw, the bedding layers, and the compression stress field jointly control the failure modes of the shale specimens. It was found that the α=0° specimen failed due to tension splitting, the α=30° specimen failed due to tension splitting and shear across the matrix, the α=60 specimen failed due to shear across the shale matrix and shear along the bedding layers, and the α=90° specimen failed due to tension along the bedding layers and shear across the shale matrix. The study can provide some references to the construction of complex crack networks in shale gas engineering.
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- 2022
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39. Preparation and Properties of Cyclodextrin Inclusion Complexes of Hyperoside
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Xinyu Zhang, Jianqing Su, Xiaoya Wang, Xueyan Wang, Ruixue Liu, Xiang Fu, Ying Li, Jiaojiao Xue, Xiaoli Li, Rui Zhang, and Xiuling Chu
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Hyperoside ,inclusion complexes ,antioxidant activity ,Organic chemistry ,QD241-441 - Abstract
In order to improve the aqueous solubility and enhance the bioavailability of Hyperoside (Hyp), three inclusion complexes (ICs) of Hyp with 2-hydroxypropyl-β-cyclodextrin (2H-β-CD), β-cyclodextrin (β-CD), and methyl-β-cyclodextrin (M-β-CD) were prepared using the ultrasonic method. The characterization of the inclusion complexes (ICs) was achieved using Fourier-transform infrared spectroscopy (FTIR), scanning electronic microscopy (SEM), X-ray powder diffraction (XRPD), thin-layer chromatography (TLC), and 1H nuclear magnetic resonance (1H NMR). The effects of the ICs on the solubility and antioxidant activity of Hyp were investigated. A Job’s plot revealed that the Hyp formed ICs with three kinds of cyclodextrin (CD), all at a 1:1 stoichiometric ratio. The FTIR, SEM, XRPD, TLC, and 1H NMR results confirmed the formation of inclusion complexes. The water solubility of the IC of Hyp with 2-hydroxypropyl-β-cyclodextrin was enhanced 9-fold compared to the solubility of the original Hyp. The antioxidant activity tests showed that the inclusion complexes had higher antioxidant activities compared to free Hyp in vitro and the H2O2–RAW264.7 cell model. Therefore, encapsulation with CDs can not only improve Hyp’s water solubility but can also enhance its biological activity, which provides useful information for the potential application of complexation with Hyp in a clinical context.
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- 2022
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40. Laser Vibration Characteristics of Marble Specimens and Failure Criterion
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Qiang Xie, Jun Duan, Yuxin Ban, Xiang Fu, and Shilin Liu
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laser vibration characteristics ,laser Doppler vibrometry (LDV) ,uniaxial compression test ,Brazilian test ,dominant frequency ,early warning ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Rock failure and instability usually lead to significant engineering disasters. This paper aims to establish an experimental failure criterion to predict rock failure via testing the laser vibration characteristics of marble specimens. Uniaxial compression tests and Brazilian tests were carried out on marble specimens coupled with acoustic emission technology and laser Doppler vibrometry measurement technology. The whole laser vibration waveform of the marble specimen was divided into elastic stage, plastic stage, and failure stage. Although different frequency spectrum characteristics were identified in different waveform phases, a wide frequency spectrum was always present prior to rock failure. Furthermore, the wide frequency band frequency spectra characteristics took place 30.9 s and 21.3 s earlier than the rapid increase of the acoustic emission counts in the uniaxial compression test and Brazilian test, respectively. Taking the wide frequency spectrum as a failure criterion for the failure of loaded marble is quick, convenient, and reasonable. Using laser Doppler vibrometry measurement has the advantages of being remote, non-contacting, and earlier warning. This research can provide a reference for the further study of forecasting rock failure.
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- 2022
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41. High-frequency Driving Circuit and Loss Analysis of SIC MOSFET Based on Discrete Components
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Yue, Gai-Li, Wang, Zi-Jing, Xiang, Fu-Wei, and Xu, Zhen-Zhen
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- 2024
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42. Benchmarking Variables for Checkpointing in HPC Applications.
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Xiang Fu, Xin Huang, Wubiao Xu, Weiping Zhang, Shiman Meng, Luanzheng Guo, and Kento Sato
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- 2024
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43. Automated Surgical Knot Tying on Mini-Incision with Micro-Suture based on Dual-Arm Nanorobot under Stereo Microscope.
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Yujie Jiang, Xiang Fu, Chengxi Zhong, Teng Li 0017, Haojian Lu, and Song Liu 0003
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- 2024
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44. Study on the Influence Law of Sand Production After Fracturing in Deep Sandstone Reservoirs
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Sun, Bo, Cheng, Yuan-fang, Han, Zhong-ying, Wang, Yun-han, Yan, Chuan-liang, Xue, Ming-yu, Shan, Xiang-fu, Li, Yang, Wu, Wei, Series Editor, and Lin, Jia'en, editor
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- 2024
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45. Studying the properties of compressible MHD turbulence by synchrotron fluctuation statistics
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Wang, Ru-Yue, Zhang, Jian-Fu, Lazarian, Alex, Xiao, Hua-Ping, and Xiang, Fu-Yuan
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We study the observable properties of compressible MHD turbulence covering different turbulence regimes, based on synthetic synchrotron observations arising from 3D MHD numerical simulations. Using the synchrotron emissivity and intensity, we first explore how the cosmic ray spectral indices affect the measurements of turbulence properties by employing normalized correlation functions. We then study how the anisotropy of synchrotron total and polarization intensities arising from three fundamental MHD modes vary with the viewing angle, i.e., the angle between the mean magnetic field and the line of sight. We employ the ratio of quadrupole moment to the monopole one (QM) for this purpose. Our numerical results demonstrate that: (1) the two-point correlation function of synchrotron statistics for the arbitrary cosmic ray spectral index is related to the special case of magnetic field index $\gamma=2$ in agreement with the analytical formulae provided by Lazarian \& Pogosyan (2012); (2) the anisotropy of synchrotron total and polarization intensities arising from Alfv\'en and slow modes increases with the increase of the viewing angle, while that of fast mode remains almost unchanged with the viewing angle; (3) the analytical formulae of synchrotron intensities for studying turbulence can be applied to describing statistics of polarization intensities, and the QM can be successfully used to recover turbulence anisotropy. This study validates Lazarian \& Pogosyan's analytical approach and opens a way to study turbulence from observations., Comment: Accepted by ApJ. 15 pages, 9 figures and 1 Table
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- 2022
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46. Visual Servo Control for Workspace Navigation of Nanorobot End-Effector Inside SEM.
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Teng Li 0017, Yuting Yang, Xiang Fu, Zhenhuan Sun, You Fu Li, and Song Liu 0003
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- 2024
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47. Virtual node graph neural network for full phonon prediction.
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Ryotaro Okabe, Abhijatmedhi Chotrattanapituk, Artittaya Boonkird, Nina Andrejevic, Xiang Fu 0005, Tommi S. Jaakkola, Qichen Song, Thanh Nguyen, Nathan C. Drucker, Sai Mu, Yao Wang, Bolin Liao, Yongqiang Cheng 0006, and Mingda Li
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- 2024
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48. Iterative Learning Embedded Composite Model Reference Adaptive Control for Off-Axis In-Situ Rotation in Nanorobotic Manipulation.
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Heng Zhang, Xiang Fu, Song Liu 0003, and Yang Wang 0063
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- 2024
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49. MOFDiff: Coarse-grained Diffusion for Metal-Organic Framework Design.
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Xiang Fu 0005, Tian Xie, Andrew S. Rosen, Tommi S. Jaakkola, and Jake Smith
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- 2024
50. Exploring ferroelectric and photovoltaic attributes of Pna21-LaWN3: A first-principles approach
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Lai, Guo-Xia, Huang, Ze-Jiang, Xu, Hua-Kai, Tian, Ya-Yi, Huang, Li-Fang, Xu, Xiang-Fu, Lu, Ji, Chen, Xing-Yuan, and Cheng, Yun-Hua
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- 2024
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