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Your search keyword '"Wildwater, Marjolein"' showing total 8 results
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8 results on '"Wildwater, Marjolein"'

2. 3′sialyllactose and 6′sialyllactose enhance performance in endurance‐type exercise through metabolic adaptation

Author

Arellano Spadaro, Jesus, primary, Hishida, Yukihiro, additional, Matsunaga, Yukihisa, additional, van Es‐Remers, Monique, additional, Korthout, Henrie, additional, Kim, Hye Kyong, additional, Poppelaars, Eefje, additional, Keizer, Hiskias, additional, Iliopoulou, Eva, additional, van Duijn, Bert, additional, Wildwater, Marjolein, additional, and van Rijnberk, Lotte, additional

Published
2023
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3. DARTpaths, an in silico platform to investigate molecular mechanisms of compounds

Author

Bhalla, Diksha, Steijaert, Marvin N, Poppelaars, Eefje S, Teunis, Marc, van der Voet, Monique, Corradi, Marie, Dévière, Elisabeth, Noothout, Luke, Tomassen, Wilco, Rooseboom, Martijn, Currie, Richard A, Krul, Cyrille, Pieters, Raymond, van Noort, Vera, Wildwater, Marjolein, Bhalla, Diksha, Steijaert, Marvin N, Poppelaars, Eefje S, Teunis, Marc, van der Voet, Monique, Corradi, Marie, Dévière, Elisabeth, Noothout, Luke, Tomassen, Wilco, Rooseboom, Martijn, Currie, Richard A, Krul, Cyrille, Pieters, Raymond, van Noort, Vera, and Wildwater, Marjolein

Abstract

SUMMARY: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied to predict developmental and reproductive toxicity (DART) and implemented into an in silico platform, called DARTpaths.AVAILABILITY AND IMPLEMENTATION: All code is available on GitHub https://github.com/Xpaths/dartpaths-app under Apache license 2.0, detailed overview with demo is available at https://www.vivaltes.com/dartpaths/.SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Published
2023

4. DARTpaths, an in silico platform to investigate molecular mechanisms of compounds

Author

IRAS OH Toxicology, Bhalla, Diksha, Steijaert, Marvin N, Poppelaars, Eefje S, Teunis, Marc, van der Voet, Monique, Corradi, Marie, Dévière, Elisabeth, Noothout, Luke, Tomassen, Wilco, Rooseboom, Martijn, Currie, Richard A, Krul, Cyrille, Pieters, Raymond, van Noort, Vera, Wildwater, Marjolein, IRAS OH Toxicology, Bhalla, Diksha, Steijaert, Marvin N, Poppelaars, Eefje S, Teunis, Marc, van der Voet, Monique, Corradi, Marie, Dévière, Elisabeth, Noothout, Luke, Tomassen, Wilco, Rooseboom, Martijn, Currie, Richard A, Krul, Cyrille, Pieters, Raymond, van Noort, Vera, and Wildwater, Marjolein

Published
2023

5. DARTpaths, an in silico platform to investigate molecular mechanisms of compounds

Author

Bhalla, Diksha, primary, Steijaert, Marvin N, additional, Poppelaars, Eefje S, additional, Teunis, Marc, additional, van der Voet, Monique, additional, Corradi, Marie, additional, Dévière, Elisabeth, additional, Noothout, Luke, additional, Tomassen, Wilco, additional, Rooseboom, Martijn, additional, Currie, Richard A, additional, Krul, Cyrille, additional, Pieters, Raymond, additional, van Noort, Vera, additional, and Wildwater, Marjolein, additional

Published
2022
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7. Additional file 10 of C. elegans as a test system to study relevant compounds that contribute to the specific health-related effects of different cannabis varieties

Author

van Es-Remers, Monique, Spadaro, Jesus Arellano, Poppelaars, Eefje, Kim, Hye Kyong, van Haaster, Marieke, de Wit, Marcel, ILiopoulou, Eva, Wildwater, Marjolein, and Korthout, Henrie

Abstract

Additional file 10: Additional file S10. Overview of the selected cannabis varieties used in this study and the effects as based on 25 years of human experiences. The effects were reported by surveys among 200 patients in the Netherlands using medicinal cannabis from MariPharms medicinal-cannabis breeding program. Varieties in green columns: Δ9 -tetrahydrocannabinol (THC)-rich; varieties in brown columns: cannabidiol (CBD)-rich varieties. √ indicates an reported effect, blank wells indicates an effect not reported by the patients.

Published
2022
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8. DARTpaths, an in silico platform to investigate molecular mechanisms of compounds.

Author

Bhalla D, Steijaert MN, Poppelaars ES, Teunis M, van der Voet M, Corradi M, Dévière E, Noothout L, Tomassen W, Rooseboom M, Currie RA, Krul C, Pieters R, van Noort V, and Wildwater M

Subjects
Software, Algorithms
Abstract

Summary: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied to predict developmental and reproductive toxicity (DART) and implemented into an in silico platform, called DARTpaths., Availability and Implementation: All code is available on GitHub https://github.com/Xpaths/dartpaths-app under Apache license 2.0, detailed overview with demo is available at https://www.vivaltes.com/dartpaths/., Supplementary Information: Supplementary data are available at Bioinformatics online., (© The Author(s) 2022. Published by Oxford University Press.)

Published
2023
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