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3 results on '"Webber, Larry"'

1. The Timing and Sequence of Cardiovascular Health Decline

Author

Pool, Lindsay R., primary, Krefman, Amy E., additional, Labarthe, Darwin R., additional, Greenland, Philip, additional, Juonala, Markus, additional, Kähönen, Mika, additional, Lehtimäki, Terho, additional, Day, Rena Sue, additional, Bazzano, Lydia A., additional, Van Horn, Linda, additional, Liu, Lei, additional, Fernandez-Alonso, Camilo, additional, Webber, Larry S., additional, Pahkala, Katja, additional, Laitinen, Tomi T., additional, Raitakari, Olli T., additional, Lloyd-Jones, Donald M., additional, and Allen, Norrina B., additional

Published
2021
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2. Influential Periods in Longitudinal Clinical Cardiovascular Health Scores.

Author

Krefman, Amy E, Labarthe, Darwin, Greenland, Philip, Pool, Lindsay, Aguayo, Liliana, Juonala, Markus, Kähönen, Mika, Lehtimäki, Terho, Day, R Sue, Bazzano, Lydia, Muggeo, Vito M R, Horn, Linda Van, Liu, Lei, Webber, Larry S, Pahkala, Katja, Laitinen, Tomi T, Raitakari, Olli, Lloyd-Jones, Donald M, and Allen, Norrina B

Subjects
CARDIOVASCULAR disease prevention, CARDIOVASCULAR diseases risk factors, BLOOD pressure, CONFIDENCE intervals, AGE distribution, HEALTH status indicators, BLOOD sugar, REGRESSION analysis, DESCRIPTIVE statistics, BODY mass index, LONGITUDINAL method, CHOLESTEROL
Abstract

The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e. body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 years were included. These factors were categorized and summed into a clinical CVH score ranging from 0 (worst) to 8 (best). Adjusted, segmented, linear mixed models were used to estimate the change in CVH over time. Among the 18,343 participants, 9,461 (52%) were female and 12,346 (67%) were White. The baseline mean (standard deviation) clinical CVH score was 6.9 (1.2) at an average age of 17.6 (8.1) years. Two inflection points were estimated: at 16.9 years (95% confidence interval: 16.4, 17.4) and at 37.2 years (95% confidence interval: 32.4, 41.9). Late adolescence and early middle age appear to be influential periods during which the loss of CVH accelerates. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
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3. Influential Periods in Longitudinal Clinical Cardiovascular Health Scores

Author

Mika Kähönen, Lei Liu, Vito M. R. Muggeo, Amy Krefman, R. Sue Day, Liliana Aguayo, Donald M. Lloyd-Jones, Tomi T. Laitinen, Lydia A. Bazzano, Larry S. Webber, Terho Lehtimäki, Linda Van Horn, Norrina B. Allen, Katja Pahkala, Olli T. Raitakari, Philip Greenland, Markus Juonala, Lindsay R. Pool, Darwin R. Labarthe, Tampere University, Department of Clinical Physiology and Nuclear Medicine, Clinical Medicine, Department of Clinical Chemistry, Krefman, Amy E, Labarthe, Darwin, Greenland, Philip, Pool, Lindsay, Aguayo, Liliana, Juonala, Marku, Kähönen, Mika, Lehtimäki, Terho, Day, R Sue, Bazzano, Lydia, Muggeo, Vito, Van Horn, Linda, Liu, Lei, Webber, Larry S, Pahkala, Katja, Laitinen, Tomi T, Raitakari, Olli, Lloyd-Jones, Donald M, and Allen, Norrina B

Subjects
Adult, Male, Adolescent, Epidemiology, Cardiovascular health, Health Behavior, 3121 Internal medicine, Young Adult, Sex Factors, cohort studies, prevention, Humans, longitudinal studies, risk factors, Medicine, AcademicSubjects/MED00860, Young adult, Child, Aged, business.industry, Age Factors, cardiovascular health, Original Contribution, Middle Aged, Late adolescence, 3126 Surgery, anesthesiology, intensive care, radiology, Middle age, Confidence interval, 3142 Public health care science, environmental and occupational health, Blood pressure, Heart Disease Risk Factors, Female, adolescence, business, Body mass index, cardiovascular epidemiology, Demography, Cohort study
Abstract

The prevalence of ideal cardiovascular health (CVH) among adults in the United States is low and decreases with age. Our objective was to identify specific age windows when the loss of CVH accelerates, to ascertain preventive opportunities for intervention. Data were pooled from 5 longitudinal cohorts (Project Heartbeat!, Cardiovascular Risk in Young Finns Study, The Bogalusa Heart Study, Coronary Artery Risk Development in Young Adults, Special Turku Coronary Risk Factor Intervention Project) from the United States and Finland from 1973 to 2012. Individuals with clinical CVH factors (i.e., body mass index, blood pressure, cholesterol, blood glucose) measured from ages 8 to 55 years were included. These factors were categorized and summed into a clinical CVH score ranging from 0 (worst) to 8 (best). Adjusted, segmented, linear mixed models were used to estimate the change in CVH over time. Among the 18,343 participants, 9,461 (52%) were female and 12,346 (67%) were White. The baseline mean (standard deviation) clinical CVH score was 6.9 (1.2) at an average age of 17.6 (8.1) years. Two inflection points were estimated: at 16.9 years (95% confidence interval: 16.4, 17.4) and at 37.2 years (95% confidence interval: 32.4, 41.9). Late adolescence and early middle age appear to be influential periods during which the loss of CVH accelerates.

Published
2021

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