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Purpose: To report a case of foveolitis associated with dengue fever. Methods: Retrospective, observational case report. Case description: A 12-year-old male child, presented to the retina department with complaints of sudden blurring of vision in left eye since 1 week following dengue fever. His presenting visual acuity in left eye was 20/60, N8. Fundus showed wellcircumscribed, pale yellow-orange lesion at the foveal center in LE. Retinal imaging findings were consistent with the diagnosis of foveolitis. Results: Foveolitis and macular swelling were found to resolve over time on serial OCT, with visual acuity improving to 20/20,N6 with a resolution of scotoma. Conclusion: Infection with dengue virus might be associated with foveolitis. We suggest that serial OCT be performed to monitor maculopathy.

Neuraminidase inhibitors are a type of medication that inhibits the neuraminidase enzyme. They are type of antiviral medication that is often used to treat influenza. In this paper we have taken 53 Compounds which are derivatives of Thiourea and Thiazolidine-4-Carboxylic acid derivatives. We modelled the pIC50 activity using RDF115p, E2s, R1i Parameters. The excellent value of r2 = 0.725 Shows that following model is best suitable. We also Performed docking study and the best docking score is -28.1891, and the best predicted activity is 8.36.