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Climate trends and weather indicators are used in several research fields due to their importance in statistical modeling, frequently used as covariates. Usually, climate indicators are available as grid files with different spatial and time resolutions. The availability of a time series of climate indicators compatible with administrative boundaries is scattered in Brazil, not fully available for several years, and produced with diverse methodologies. In this paper, we propose time series of climate indicators for the Brazilian municipalities produced using zonal statistics derived from the ERA5-Land reanalysis indicators. As a result, we present datasets with zonal statistics of climate indicators with daily data, covering the period from 1950 to 2022.

Resumo Fundamento: A maioria das mortes por doenças cardiovasculares ocorrem em países de renda baixa e média, e o infarto do miocárdio é uma das condições com maior risco de morte. Objetivos: Avaliar a mortalidade hospitalar por todas as causas em pacientes admitidos por infarto do miocárdio (IAMCSST e IAMSSST) na América Latina e no Caribe no ano de 2000 em diante. Métodos: Realizamos uma busca sistemática em bancos de dados eletrônicos por estudos do tipo coorte que relataram morte hospitalar por IAMCSST e IAMSSST. Foi realizada uma metanálise e um valor de p

Background: Dermatologic diseases are one of the most frequent health conditions. The impact on the quality of life of patients is evident and the negative effects on health can range from psychological and physical incapacity to even death. Because of the serious impact that dermatologic diseases can have on one's health, prevention and treatment of these conditions should be urgently included in global health strategies. Advancing scientific knowledge about traditional techniques has been gaining acknowledgement due to the contributions they can provide to global health. Objective: This study aims to analyse the current evidence on the effectiveness of traditional Chinese phytopharmacology (herbal medicine) on dermatologic conditions and to inform potential applications within western healthcare settings. Methodology: A systematic literature search was conducted in PubMed, Cochrane, Science Direct and Scielo databases to identify randomized clinical trials on Chinese herbal medicine for dermatologic conditions. Studies with low or moderate quality were excluded. Results: Our literature search yielded 151 studies, 135 after the removal of duplicates. After title and abstract screening, 38 studies were selected for retrieval. Full-text and quality assessment was performed on 33 studies, and 18 studies were included in the final analysis. Conclusions: Evidence suggests that Chinese phytopharmacology can be used as a complementary treatment for some dermatologic conditions. Major benefits seem to exist due to the presence of components that possess anti-fungal, anti-bacterial, anti-viral, and anti-inflammatory action, as well as immunomodulatory effects. More studies should be conducted to confirm the complementary benefits of Chinese phytopharmacology for dermatologic conditions. Registration: The protocol has been registered with the International Prospective Registry for Systematic Reviews (PROSPERO CRD42022308304).

Este artigo objetivou discutir se haveria ou não coerência entre o que os Ministros do STF ensinam em suas doutrinas e aquilo que eles decidem em casos difíceis enquanto juízes constitucionais, considerando as polêmicas levantadas pelo paradigma neoconstitucional. Para tanto, construiu-se uma pesquisa bibliográfica e documental amparada no método hipotético-dedutivo. Acreditava-se inicialmente que o grau de coerência entre o ensinado e o decidido oscilaria conforme os interesses extrajurídicos em jogo. Para testar essa hipótese, a pesquisa foi estruturada em três partes. Na primeira, foram debatidos os principais elementos que compõem esse paradigma. Na segunda, analisou-se as doutrinas dos Ministros Mendes, Moraes e Barroso. Na terceira, foram estudados os votos deles na ADO 26 – sobre a equiparação da homotransfobia ao crime de racismo, e na ADI 5.526 – sobre a aplicabilidade de cautelares penais aos congressistas. Ao final, refutou-se a hipótese levantada, pois o grau de vinculação às ideias e métodos neoconstitucionais manifestado pelos Ministros em suas respectivas doutrinas também foi verificado nas ações analisadas. Como reflexão final, a pesquisa aponta para a necessidade de pesquisar empiricamente a atuação da jurisdição constitucional como forma de fiscalizá-la e controlá-la democraticamente.

ABSTRACT BACKGROUND: Coronavirus disease 2019 (COVID-19) can damage cardiac tissue by increasing troponin levels and inducing arrhythmias, myocarditis, and acute coronary syndrome. OBJECTIVES: To analyze the impact of COVID-19 on cardiac autonomic control in mechanically ventilated intensive care unit (ICU) patients. DESIGN AND SETTING: This cross-sectional analytical study of ICU patients of both sexes receiving mechanical ventilation was conducted in a tertiary hospital. METHODS: Patients were divided into COVID-19-positive (COVID(+)) and COVID-19-negative (COVID(-)) groups. Clinical data were collected and heart rate variability (HRV) records obtained using a heart rate monitor. RESULTS: The study sample comprised 82 subjects: 36 (44%) in the COVID(-) group (58.3% female; median age, 64.5 years) and 46 (56%) in the COVID(+) group (39.1% females; median age, 57.5 years). The HRV indices were lower than the reference values. An intergroup comparison identified no statistically significant differences in the mean normal-to-normal (NN) interval, standard deviation of the NN interval, or root mean square of successive differences in NN intervals. The COVID(+) group had an increased low frequency (P = 0.05), reduced high frequency (P = 0.045), and increased low frequency/high frequency (LF/HF) ratio (P = 0.048). There was a weak positive correlation between LF/HF and length of stay in the COVID(+) group. CONCLUSION: Patients who received mechanical ventilation had lower overall HRV indices. COVID(+) patients who received mechanical ventilation had lower vagal HRV components. These findings likely indicate clinical applicability, as autonomic control impairments are associated with a greater risk of cardiac death.

Background Ventriculoperitoneal shunt (VPS) has become the standard treatment for congenital hydrocephalus. In the neurosurgical practice, it is a common procedure which usually results in low rates of complication. However, some serious complications can occur, including infections, intestinal perforation, and even death.

Spatially misaligned data can be fused by using a Bayesian melding model that assumes that underlying all observations there is a spatially continuous Gaussian random field. This model can be employed, for instance, to forecast air pollution levels through the integration of point data from monitoring stations and areal data derived from satellite imagery. However, if the data present preferential sampling, that is, if the observed point locations are not independent of the underlying spatial process, the inference obtained from models that ignore such a dependence structure may not be valid. In this paper, we present a Bayesian spatial model for the fusion of point and areal data that takes into account preferential sampling. Fast Bayesian inference is performed using the integrated nested Laplace approximation and the stochastic partial differential equation approaches. The performance of the model is assessed using simulated data in a range of scenarios and sampling strategies that can appear in real settings. The model is also applied to predict air pollution in the USA. [ABSTRACT FROM AUTHOR]