27 results on '"Veber, Benoit"'
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2. Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial
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Bouglé, Adrien, Tuffet, Sophie, Federici, Laura, Leone, Marc, Monsel, Antoine, Dessalle, Thomas, Amour, Julien, Dahyot-Fizelier, Claire, Barbier, François, Luyt, Charles-Edouard, Langeron, Olivier, Cholley, Bernard, Pottecher, Julien, Hissem, Tarik, Lefrant, Jean-Yves, Veber, Benoit, Legrand, Matthieu, Demoule, Alexandre, Kalfon, Pierre, Constantin, Jean-Michel, Rousseau, Alexandra, Simon, Tabassome, and Foucrier, Arnaud
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- 2022
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3. Dynamic metabolic changes measured by indirect calorimetry during the early phase of septic shock: a prospective observational pilot study
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Occhiali, Emilie, Urli, Maximilien, Pressat-Laffouilhère, Thibaut, Achamrah, Najate, Veber, Benoit, and Clavier, Thomas
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- 2022
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4. Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study
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Bassetti, Matteo, Vena, Antonio, Giacobbe, Daniele R., Trucchi, Cecilia, Ansaldi, Filippo, Antonelli, Massimo, Adamkova, Vaclava, Alicino, Cristiano, Almyroudi, Maria-Panagiota, Atchade, Enora, Azzini, Anna M., Brugnaro, Pierluigi, Carannante, Novella, Peghin, Maddalena, Berruti, Marco, Carnelutti, Alessia, Castaldo, Nadia, Corcione, Silvia, Cortegiani, Andrea, Dimopoulos, George, Dubler, Simon, García-Garmendia, José L., Girardis, Massimo, Cornely, Oliver A., Ianniruberto, Stefano, Kullberg, Bart Jan, Lagrou, Katrien, Lebihan, Clement, Luzzati, Roberto, Malbrain, Manu, Merelli, Maria, Marques, Ana J., Martin-Loeches, Ignacio, Mesini, Alessio, Paiva, José-Artur, Raineri, Santi Maurizio, Rautemaa-Richardson, Riina, Schouten, Jeroen, Spapen, Herbert, Tasioudis, Polychronis, Timsit, Jean-François, Tisa, Valentino, Tumbarello, Mario, Van den Berg, Charlotte H. S. B., Veber, Benoit, Venditti, Mario, Voiriot, Guillaume, Wauters, Joost, Zappella, Nathalie, and Montravers, Philippe
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- 2022
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5. La réforme du 2e cycle des études médicales - Quels objectifs, quelle organisation, dans quels délais ?
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Veber, Benoît
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- 2022
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6. Correction to: Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial
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Bouglé, Adrien, Tuffet, Sophie, Federici, Laura, Leone, Marc, Monsel, Antoine, Dessalle, Thomas, Amour, Julien, Dahyot-Fizelier, Claire, Barbier, François, Luyt, Charles-Edouard, Langeron, Olivier, Cholley, Bernard, Pottecher, Julien, Hissem, Tarik, Lefrant, Jean-Yves, Veber, Benoit, Legrand, Matthieu, Demoule, Alexandre, Kalfon, Pierre, Constantin, Jean-Michel, Rousseau, Alexandra, Simon, Tabassome, and Foucrier, Arnaud
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- 2022
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7. Critical pathways for controlled donation after circulatory death in France
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Le Dorze, Matthieu, Martin-Lefèvre, Laurent, Santin, Gaëlle, Robert, René, Audibert, Gérard, Megarbane, Bruno, Puybasset, Louis, Dorez, Didier, Veber, Benoît, Kerbaul, François, and Antoine, Corinne
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- 2022
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8. Conflit en situation de limitation ou d’arrêt de traitement en réanimation
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Brunel, Elodie, Gateau, Valérie, Guibet Lafaye, Caroline, Kandelman, Stanislas, Lallemant, Florence, Le Boudec, Anne, Ledorze, Matthieu, Muller, Laurent, Nouette-Gaulain, Karine, Perrigault, Pierre-François, Rutter, Nadège, Samain, Emmanuel, Visquesnel, Gérald, Zilberstein, Luca, Michel, Fabrice, Claudot, Frédérique, and Veber, Benoit
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- 2022
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9. Le Collège National des Enseignants d’Anesthésie et de Réanimation (CNEAR)
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Bouzat, Pierre, Bougle, Adrien, Jabaudon, Matthieu, Dureuil, Bertrand, Gayat, Etienne, Bounes, Fanny, Clavier, Thomas, Besch, Guillaume, Chanques, Gérald, Fischer, Marc-Olivier, Frasca, Denis, Orliaguet, Gilles, Raux, Mathieu, Samain, Emmanuel, Tran-Dinh, Alexy, Plaud, Benoît, Velly, Lionel, Veber, Benoît, and Pottecher, Julien
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- 2022
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10. Reducing diarrhoea in an adult surgical intensive care unit: A quality improvement study.
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Occhiali, Emilie, Rodrigues, Bastien, Prieur, Wendy, Tiarci, Safia, Carmon, Nicolas, Veber, Benoit, and Achamrah, Najate
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DIARRHEA prevention ,INTENSIVE care units ,LENGTH of stay in hospitals ,STATISTICAL significance ,DIARRHEA ,CAREGIVERS ,NURSING ,CRITICALLY ill ,PATIENTS ,HEALTH outcome assessment ,FISHER exact test ,MANN Whitney U Test ,PRE-tests & post-tests ,SURVEYS ,CRITICAL care nurses ,MEDICAL protocols ,QUALITY assurance ,CRITICAL care medicine ,DESCRIPTIVE statistics ,DATA analysis software ,DISEASE management - Abstract
Background: Although diarrhoea is a real source of morbidity for critically ill patients, this issue has been little studied, making it difficult to understand its mechanisms and management. Aims: We conducted a quality improvement study in an adult surgical intensive care unit before/after the implementation of a specific protocol to firstly improve diarrhoea management for patient benefit and secondly to understand the impact on caregivers. Study design: The first part of this before/after study consisted in assessing the proportion of patients receiving an anti‐diarrheal treatment before (phase I)/after (phase II) the implementation of the protocol. The second part of the study was to survey the caregivers on this topic. Results: Sixty four adults were included (33 in phase I; 31 in phase II) with 280 diarrheal episodes (129 in phase I; 151 in phase II). The proportion of patients who received at least one anti‐diarrheal treatment was similar between the two phases (79% (26/33) vs. 68% (21/31), p =.40). Diarrhoea incidence was also similar (9% (33 patients/368 admissions) vs. 11% (31 patients/275 admissions), p =.35). The delay to initiate at least one treatment was significantly shorter in phase II (2 days [1–7] vs. 0 day [0–2]; p <.001). The patients' rehabilitation was no longer impacted by the occurrence of a diarrheal episode in phase II (39% (13/33) vs. 0% (0/31), p <.001). Eighty team members completed the surveys in phase I and 70 in phase II. Caregivers perceived diarrhoea like a burden and its economic impact remained high. Conclusions: The implementation of a protocol for the management of ICU diarrhoea did not increase the proportion of patients treated, but it did significantly improve the delay to initiate a treatment. The patients' rehabilitation was no longer affected by diarrhoea. Relevance to clinical practice: The use of specific anti‐diarrhoea guidelines may help to reduce the burden of diarrhoea in an ICU. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Gender differences in professional social networks use among critical care researchers
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Demailly, Zoé, primary, Brulard, Geoffroy, additional, Tamion, Fabienne, additional, Veber, Benoit, additional, Occhiali, Emilie, additional, and Clavier, Thomas, additional
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- 2023
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12. Gender-based violence among healthcare students: prevalence, description and associated factors
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Tavolacci, Marie-Pierre, primary, Karmaly, Alice, additional, Gharbi-hamza, Najla, additional, Veber, Benoit, additional, and Ladner, Joel, additional
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- 2023
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13. Gender-based violence among healthcare students: Prevalence, description and associated factors.
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Tavolacci, Marie-Pierre, Karmaly, Alice, El Gharbi-Hamza, Najla, Veber, Benoit, and Ladner, Joel
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VIOLENCE against women ,GENDER-based violence ,STUDENT volunteers ,SEXISM in language ,MEDICAL personnel ,NURSING schools - Abstract
Objectives: The aims of the current study were 1) to provide the prevalence of five types of gender-based violence (GBV) among male and female healthcare students; 2) to describe perpetrators' status, where the GBV occurred, and psychological and behavioural impacts of the GBV; and 3) to identify factors associated with GBV. Design: A cross-sectional study was conducted among voluntary healthcare students in France. Setting: Health Campus at Rouen and nursing schools in Normandy, France. Participants: Volunteer healthcare students of 18 years and over. Data collected: Five types of GBV were recorded: GBV1: damage to a person's image due to a sexual connotation on social networks, GBV2: sexist remarks and behaviour, GBV3: comments with sexual connotations, GBV4: sexual assaults and GBV5: rape or attempted rape. Perpetrators' status, where the GBV occurred, psychological and behavioural impacts of GBV were also recorded. Results: One thousand one hundred and fifty-two students were included. The mean age was 20.8 years (SD = 2.26), 82.6% of students were women (0.4% non-binary). Since the beginning of their healthcare study, 41.2% of students CI 95% [39.7–42.6] were victim of at least one type of GBV: 15.8% among men CI 95% [13.2–18.4] and 46.0% CI 95% [44.4–47.6] among women (p < 0.001). The perpetrators were student peers, regardless of the type of GBV, healthcare workers for the GB2 and GBV3, and patients except for GBV5. The main consequences of GBV on health was psychological and eating related. After multivariate analysis, being a woman, LGBTQ+ (Lesbian, Gay, Bi, Trans, Queer and other), a nurse, a physiotherapist student, having a job, living with roommates and year of study were risk factors for GBV. Conclusion: GBV is so common at healthcare universities and could have such severe consequences for students that more work is needed to generate a culture change and ensure safe learning environments. [ABSTRACT FROM AUTHOR]
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- 2023
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14. Trends in major intensive care medicine journals: A machine learning approach
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Popoff, Benjamin, primary, Occhiali, Émilie, additional, Grangé, Steven, additional, Bergis, Alexandre, additional, Carpentier, Dorothée, additional, Tamion, Fabienne, additional, Veber, Benoit, additional, and Clavier, Thomas, additional
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- 2022
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15. Anticoagulation Monitoring with Activated Partial ThromboPlastin Time and Anti-Xa Activity in Intensive Care Unit Patients: Interest of Thrombin Generation Assay
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Billoir, Paul, primary, Elie, Thomas, additional, Levy, Jerrold H., additional, Besnier, Emmanuel, additional, Dureuil, Bertrand, additional, Veber, Benoit, additional, Le Cam-Duchez, Véronique, additional, and Clavier, Thomas, additional
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- 2022
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16. Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome Associated with COVID-19: An Emulated Target Trial Analysis
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Hajage, David, primary, Combes, Alain, additional, Guervilly, Christophe, additional, Lebreton, Guillaume, additional, Mercat, Alain, additional, Pavot, Arthur, additional, Nseir, Saad, additional, Mekontso-Dessap, Armand, additional, Mongardon, Nicolas, additional, Mira, Jean Paul, additional, Ricard, Jean-Damien, additional, Beurton, Alexandra, additional, Tachon, Guillaume, additional, Kontar, Loay, additional, Le Terrier, Christophe, additional, Richard, Jean Christophe, additional, Mégarbane, Bruno, additional, Keogh, Ruth H., additional, Belot, Aurélien, additional, Maringe, Camille, additional, Leyrat, Clémence, additional, Schmidt, Matthieu, additional, Asfar, Pierre, additional, Beloncle, François, additional, Demiselle, Julien, additional, Pham, Tài, additional, Monnet, Xavier, additional, Richard, Christian, additional, Demoule, Alexandre, additional, Dres, Martin, additional, Mayaux, Julien, additional, Daubin, Cédric, additional, Descamps, Richard, additional, Joret, Aurélie, additional, Du Cheyron, Damien, additional, Pene, Frédéric, additional, Chiche, Jean-Daniel, additional, Jozwiak, Mathieu, additional, Jaubert, Paul, additional, Voiriot, Guillaume, additional, Fartoukh, Muriel, additional, Teulier, Marion, additional, Blayau, Clarisse, additional, L'Her, Erwen, additional, Aubron, Cécile, additional, Bodenes, Laetitia, additional, Ferriere, Nicolas, additional, Auchabie, Johann, additional, Le Meur, Anthony, additional, Pignal, Sylvain, additional, Mazzoni, Thierry, additional, Quenot, Jean-Pierre, additional, Andreu, Pascal, additional, Roudau, Jean-Baptiste, additional, Labruyère, Marie, additional, Preau, Sébastien, additional, Poissy, Julien, additional, Mathieu, Daniel, additional, Benhamida, Sarah, additional, Paulet, Rémi, additional, Roucaud, Nicolas, additional, Thyrault, Martial, additional, Daviet, Florence, additional, Hraiech, Sami, additional, Parzy, Gabriel, additional, Sylvestre, Aude, additional, Jochmans, Sébastien, additional, Bouilland, Anne-Laure, additional, Monchi, Mehran, additional, Danguy des Déserts, Marc, additional, Mathais, Quentin, additional, Rager, Gwendoline, additional, Pasquier, Pierre, additional, Reignier, Jean, additional, Seguin, Amélie, additional, Garret, Charlotte, additional, Canet, Emmanuel, additional, Dellamonica, Jean, additional, Saccheri, Clément, additional, Lombardi, Romain, additional, Kouchit, Yanis, additional, Jacquier, Sophie, additional, Mathonnet, Armelle, additional, Nay, Mai-Ahn, additional, Runge, Isabelle, additional, Martino, Frédéric, additional, Flurin, Laure, additional, Rolle, Amélie, additional, Carles, Michel, additional, Coudroy, Rémi, additional, W. Thille, Arnaud, additional, Frat, Jean-Pierre, additional, Rodriguez, Maeva, additional, Beuret, Pascal, additional, Tientcheu, Audrey, additional, Vincent, Arthur, additional, Michelin, Florian, additional, Tamion, Fabienne, additional, Carpentier, Dorothée, additional, Boyer, Déborah, additional, Beduneau, Gaetan, additional, Gissot, Valérie, additional, Ehrmann, Stéphan, additional, Salmon Gandonniere, Charlotte, additional, Elaroussi, Djlali, additional, Delbove, Agathe, additional, Fedun, Yannick, additional, Huntzinger, Julien, additional, Lebas, Eddy, additional, Kisoka, Grâce, additional, Grégoire, Céline, additional, Marchetta, Stella, additional, Lambermont, Bernard, additional, Argaud, Laurent, additional, Baudry, Thomas, additional, Bertrand, Pierre-Jean, additional, Dargent, Auguste, additional, Guitton, Christophe, additional, Chudeau, Nicolas, additional, Landais, Mickaël, additional, Darreau, Cédric, additional, Ferre, Alexis, additional, Gros, Antoine, additional, Lacave, Guillaume, additional, Bruneel, Fabrice, additional, Neuville, Mathilde, additional, Devaquet, Jérôme, additional, Gallot, Richard, additional, Chelha, Riad, additional, Galbois, Arnaud, additional, Jallot, Anne, additional, Chalumeau Lemoine, Ludivine, additional, Kuteifan, Khaldoun, additional, Pointurier, Valentin, additional, Jandeaux, Louise-Marie, additional, Mootien, Joy, additional, Damoisel, Charles, additional, Sztrymf, Benjamin, additional, Chommeloux, Juliette, additional, Edouard Luyt, Charles, additional, Schortgen, Frédérique, additional, Rusel, Leon, additional, Jung, Camille, additional, Gobert, Florent, additional, Vimpere, Damien, additional, Lamhaut, Lionel, additional, Sauneuf, Bertrand, additional, Charrrier, Liliane, additional, Calus, Julien, additional, Desmeules, Isabelle, additional, Painvin, Benoît, additional, Tadie, Jean-Marc, additional, Castelain, Vincent, additional, Michard, Baptiste, additional, Herbrecht, Jean-Etienne, additional, Baldacini, Mathieu, additional, Weiss, Nicolas, additional, Demeret, Sophie, additional, Marois, Clémence, additional, Rohaut, Benjamin, additional, Moury, Pierre-Henri, additional, Savida, Anne-Charlotte, additional, Couadau, Emmanuel, additional, Série, Mathieu, additional, Alexandru, Nica, additional, Bruel, Cédric, additional, Fontaine, Candice, additional, Garrigou, Sonia, additional, Courtiade Mahler, Juliette, additional, Leclerc, Maxime, additional, Ramakers, Michel, additional, Garçon, Pierre, additional, Massou, Nicole, additional, Van Vong, Ly, additional, Sen, Juliane, additional, Lucas, Nolwenn, additional, Chemouni, Franck, additional, Stoclin, Annabelle, additional, Avenel, Alexandre, additional, Faure, Henri, additional, Gentilhomme, Angélie, additional, Ricome, Sylvie, additional, Abraham, Paul, additional, Monard, Céline, additional, Textoris, Julien, additional, Rimmele, Thomas, additional, Montini, Florent, additional, Lejour, Gabriel, additional, Lazard, Thierry, additional, Etienney, Isabelle, additional, Kerroumi, Younes, additional, Dupuis, Claire, additional, Bereiziat, Marine, additional, Coupez, Elisabeth, additional, Thouy, François, additional, Hoffmann, Clément, additional, Donat, Nicolas, additional, Chrisment, Anne, additional, Blot, Rose-Marie, additional, Kimmoun, Antoine, additional, Jacquot, Audrey, additional, Mattei, Matthieu, additional, Levy, Bruno, additional, Ravan, Ramin, additional, Dopeux, Loïc, additional, Liteaudon, Jean-Mathias, additional, Roux, Delphine, additional, Rey, Brice, additional, Anghel, Radu, additional, Schenesse, Deborah, additional, Gevrey, Vincent, additional, Castanera, Jermy, additional, Petua, Philippe, additional, Madeux, Benjamin, additional, Hartman, Otto, additional, Piagnerelli, Michael, additional, Joosten, Anne, additional, Noel, Cinderella, additional, Biston, Patrick, additional, Noel, Thibaut, additional, LE Bouar, Gurvan, additional, Boukhanza, Messabi, additional, Demarest, Elsa, additional, Bajolet, Marie-France, additional, Charrier, Nathanaël, additional, Quenet, Audrey, additional, Zylberfajn, Cécile, additional, Dufour, Nicolas, additional, Mégarbane, Buno, additional, Voicu, Sébastian, additional, Deye, Nicolas, additional, Malissin, Isabelle, additional, Legay, François, additional, Debarre, Matthieu, additional, Barbarot, Nicolas, additional, Fillatre, Pierre, additional, Delord, Bertrand, additional, Laterrade, Thomas, additional, Saghi, Tahar, additional, Pujol, Wilfried, additional, Julien Cungi, Pierre, additional, Esnault, Pierre, additional, Cardinale, Mickael, additional, Hong Tuan Ha, Vivien, additional, Fleury, Grégory, additional, Brou, Marie-Ange, additional, Zafimahazo, Daniel, additional, Tran-Van, David, additional, Avargues, Patrick, additional, Carenco, Lisa, additional, Robin, Nicolas, additional, Ouali, Alexandre, additional, Houdou, Lucie, additional, Suh, Noémie, additional, Primmaz, Steve, additional, Pugin, Jérome, additional, Weiss, Emmanuel, additional, Gauss, Tobias, additional, Moyer, Jean-Denis, additional, Paugam Burtz, Catherine, additional, La Combe, Béatrice, additional, Smonig, Rolland, additional, Violleau, Jade, additional, Cailliez, Pauline, additional, Chelly, Jonathan, additional, Marchalot, Antoine, additional, Saladin, Cécile, additional, Bigot, Christelle, additional, Fayolle, Pierre-Marie, additional, Fatséas, Jules, additional, Ibrahim, Amr, additional, Resiere, Dabor, additional, Hage, Rabih, additional, Cholet, Clémentine, additional, Cantier, Marie, additional, Trouiler, Pierre, additional, Montravers, Philippe, additional, Lortat-Jacob, Brice, additional, Tanaka, Sebastien, additional, Tran Dinh, Alexy, additional, Duranteau, Jacques, additional, Harrois, Anatole, additional, Dubreuil, Guillaume, additional, Werner, Marie, additional, Godier, Anne, additional, Hamada, Sophie, additional, Zlotnik, Diane, additional, Nougue, Hélène, additional, Carteaux, Guillaume, additional, Razazi, Keyvan, additional, De Prost, Nicolas, additional, Lamraoui, Meriam, additional, Alessandri, Claire, additional, de Roux, Quentin, additional, de Roquetaillade, Charles, additional, G. Chousterman, Benjamin, additional, Mebazaa, Alexandre, additional, Gayat, Etienne, additional, Garnier, Marc, additional, Pardo, Emmanuel, additional, Satre-Buisson, Lea, additional, Gutton, Christophe, additional, Yvin, Elise, additional, Marcault, Clémence, additional, Azoulay, Elie, additional, Darmon, Michael, additional, Ait Oufella, Hafid, additional, Hariri, Geoffroy, additional, Urbina, Tomas, additional, Mazerand, Sandie, additional, Heming, Nicholas, additional, Santi, Francesca, additional, Moine, Pierre, additional, Annane, Djillali, additional, Bouglé, Adrien, additional, Omar, Edris, additional, Lancelot, Aymeric, additional, Begot, Emmanuelle, additional, Plantefeve, Gaétan, additional, Contou, Damien, additional, Mentec, Hervé, additional, Pajot, Olivier, additional, Faguer, Stanislas, additional, Cointault, Olivier, additional, Lavayssiere, Laurence, additional, Nogier, Marie-Béatrice, additional, Jamme, Matthieu, additional, Pichereau, Claire, additional, Hayon, Jan, additional, Outin, Hervé, additional, Dépret, François, additional, Coutrot, Maxime, additional, Chaussard, Maité, additional, Guillemet, Lucie, additional, Goffin, Pierre, additional, Thouny, Romain, additional, Guntz, Julien, additional, Jadot, Laurent, additional, Persichini, Romain, additional, Jean-Michel, Vanessa, additional, Georges, Hugues, additional, Caulier, Thomas, additional, Pradel, Gaël, additional, Hausermann, Marie-Hélène, additional, Nguyen-Valat, Thi My Hue, additional, Boudinaud, Michel, additional, Vivier, Emmanuel, additional, Rosseli, Sylvène, additional, Bourdin, Gaël, additional, Pommier, Christian, additional, Vinclair, Marc, additional, Poignant, Simon, additional, Mons, Sandrine, additional, Bougouin, Wulfran, additional, Bruna, Franklin, additional, Maestraggi, Quentin, additional, Roth, Christian, additional, Bitker, Laurent, additional, Dhelft, François, additional, Bonnet-Chateau, Justine, additional, Filippelli, Mathilde, additional, Morichau-Beauchant, Tristan, additional, Thierry, Stéphane, additional, Le Roy, Charlotte, additional, Saint Jouan, Mélanie, additional, Goncalves, Bruno, additional, Mazeraud, Aurélien, additional, Daniel, Matthieu, additional, Sharshar, Tarek, additional, Cadoz, Cyril, additional, Gaci, Rostane, additional, Gette, Sébastien, additional, Louis, Guillaune, additional, Sacleux, Sophe-Caroline, additional, Ordan, Marie-Amélie, additional, Cravoisy, Aurélie, additional, Conrad, Marie, additional, Courte, Guilhem, additional, Gibot, Sébastien, additional, Benzidi, Younès, additional, Casella, Claudia, additional, Serpin, Laurent, additional, Setti, Jean-Lou, additional, Besse, Marie-Catherine, additional, Bourreau, Anna, additional, Pillot, Jérôme, additional, Rivera, Caroline, additional, Vinclair, Camille, additional, Robaux, Marie-Aline, additional, Achino, Chloé, additional, Delignette, Marie-Charlotte, additional, Mazard, Tessa, additional, Aubrun, Frédéric, additional, Bouchet, Bruno, additional, Frérou, Aurélien, additional, Muller, Laura, additional, Quentin, Charlotte, additional, Degoul, Samuel, additional, Stihle, Xavier, additional, Sumian, Claude, additional, Bergero, Nicoletta, additional, Lanaspre, Bernard, additional, Quintard, Hervé, additional, Marie Maiziere, Eve, additional, Egreteau, Pierre-Yves, additional, Leloup, Guillaume, additional, Berteau, Florin, additional, Cottrel, Marjolaine, additional, Bouteloup, Marie, additional, Jeannot, Matthieu, additional, Blanc, Quentin, additional, Saison, Julien, additional, Geneau, Isabelle, additional, Grenot, Romaric, additional, Ouchike, Abdel, additional, Hazera, Pascal, additional, Masse, Anne-Lyse, additional, Demiri, Suela, additional, Vezinet, Corinne, additional, Baron, Elodie, additional, Benchetrit, Deborah, additional, Monsel, Antoine, additional, Trebbia, Grégoire, additional, Schaack, Emmanuelle, additional, Lepecq, Raphaël, additional, Bobet, Mathieu, additional, Vinsonneau, Christophe, additional, Dekeyser, Thibault, additional, Delforge, Quentin, additional, Rahmani, Imen, additional, Vivet, Bérengère, additional, Paillot, Jonathan, additional, Hierle, Lucie, additional, Chaignat, Claire, additional, Valette, Sarah, additional, Her, Benoït, additional, Brunet, Jennifier, additional, Page, Mathieu, additional, Boiste, Fabienne, additional, Collin, Anthony, additional, Bavozet, Florent, additional, Garin, Aude, additional, Dlala, Mohamed, additional, Mhamdi, Kais, additional, Beilouny, Bassem, additional, Lavalard, Alexandra, additional, Perez, Severine, additional, Veber, Benoit, additional, Guitard, Pierre-Gildas, additional, Gouin, Philippe, additional, Lamacz, Anna, additional, Plouvier, Fabienne, additional, P Delaborde, Bertrand, additional, Kherchache, Aïssa, additional, Chaalal, Amina, additional, Amouretti, Marc, additional, Freita-Ramos, Santiago, additional, Roux, Damien, additional, Constantin, Jean-Michel, additional, Assefi, Mona, additional, Lecore, Marine, additional, Selves, Agathe, additional, Prevost, Florian, additional, Lamer, Christian, additional, Shi, Ruiying, additional, Knani, Lyes, additional, Pili Floury, Sébastien, additional, Vettoretti, Lucie, additional, Levy, Michael, additional, Marsac, Lucile, additional, Dauger, Stéphane, additional, Guilmin-Crépon, Sophie, additional, Winiszewski, Hadrien, additional, Piton, Gael, additional, Soumagne, Thibaud, additional, Capellier, Gilles, additional, Putegnat, Jean-Baptiste, additional, Bayle, Frédérique, additional, Perrou, Maya, additional, Thao, Ghyslaine, additional, Géri, Guillaume, additional, Charron, Cyril, additional, Repessé, Xavier, additional, Vieillard-Baron, Antoine, additional, Guilbart, Mathieu, additional, Roger, Pierre-Alexandre, additional, Hinard, Sébastien, additional, Macq, Pierre-Yves, additional, Chaulier, Kevin, additional, Goutte, Sylvie, additional, Chillet, Patrick, additional, Pitta, Anaïs, additional, Darjent, Barbara, additional, Bruneau, Amandine, additional, Lasocki, Sigismond, additional, Leger, Maxime, additional, Gergaud, Soizic, additional, Lemarie, Pierre, additional, Terzi, Nicolas, additional, Schwebel, Carole, additional, Dartevel, Anaïs, additional, Galerneau, Louis-Marie, additional, Diehl, Jean-Luc, additional, Hauw-Berlemont, Caroline, additional, Péron, Nicolas, additional, Guérot, Emmanuel, additional, Mohebbi Amoli, Abolfazl, additional, Benhamou, Michel, additional, Deyme, Jean-Pierre, additional, Andremont, Olivier, additional, Lena, Diane, additional, Cady, Julien, additional, Causeret, Arnaud, additional, De La Chapelle, Arnaud, additional, Cracco, Christophe, additional, Rouleau, Stéphane, additional, Schnell, David, additional, Foucault, Camille, additional, Lory, Cécile, additional, Chapelle, Thibault, additional, Bruckert, Vincent, additional, Garcia, Julie, additional, Sahraoui, Abdlazize, additional, Abbosh, Nathalie, additional, Bornstain, Caroline, additional, Pernet, Pierre, additional, Poirson, Florent, additional, Pasem, Ahmed, additional, Karoubi, Philippe, additional, Poupinel, Virginie, additional, Gauthier, Caroline, additional, Bouniol, François, additional, Feuchere, Philippe, additional, Heron, Anne, additional, Carreira, Serge, additional, Emery, Malo, additional, Sophie Le Floch, Anne, additional, Giovannangeli, Luana, additional, Herzog, Nicolas, additional, Giacardi, Christophe, additional, Baudic, Thibaut, additional, Thill, Chloé, additional, Lebbah, Said, additional, Palmyre, Jessica, additional, Tubach, Florence, additional, Hajage, David, additional, Bonnet, Nicolas, additional, Ebstein, Nathan, additional, Gaudry, Stéphane, additional, Cohen, Yves, additional, Noublanche, Julie, additional, Lesieur, Olivier, additional, Sément, Arnaud, additional, Roca-Cerezo, Isabel, additional, Pascal, Michel, additional, Sma, Nesrine, additional, Colin, Gwenhaël, additional, Lacherade, Jean-Claude, additional, Bionz, Gauthier, additional, Maquigneau, Natacha, additional, Bouzat, Pierre, additional, Durand, Michel, additional, Hérault, Marie-Christine, additional, and Payen, Jean-Francois, additional
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- 2022
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17. Risk factors for poor outcome in older patients admitted in a surgical intensive care unit.
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Occhiali, Emilie, Prolange, Pierre, Cassiau, Florence, Roca, Frédéric, Veber, Benoit, and Clavier, Thomas
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SURGERY & psychology ,MORTALITY risk factors ,INTENSIVE care units ,LENGTH of stay in hospitals ,STATISTICS ,SCIENTIFIC observation ,NUTRITIONAL assessment ,FRAIL elderly ,INTENSIVE care nursing ,RESEARCH methodology ,MULTIVARIATE analysis ,PATIENTS ,ACTIVITIES of daily living ,TERTIARY care ,MANN Whitney U Test ,APACHE (Disease classification system) ,TREATMENT effectiveness ,FUNCTIONAL assessment ,PSYCHOLOGY of nurses ,HOSPITAL care of older people ,CRITICAL care medicine ,QUALITY assurance ,INTERPROFESSIONAL relations ,DESCRIPTIVE statistics ,CHI-squared test ,LOGISTIC regression analysis ,LONGITUDINAL method ,PSYCHOLOGY of physicians - Abstract
Background: The benefit of a stay in an intensive care unit (ICU) is not certain for older patients, particularly in the surgical context. Aims: The objective of this study was to identify the factors associated with an unfavourable outcome in this population. Design: Prospective, descriptive, monocentric study conducted in the surgical ICU of a French university hospital. Methods: Patients aged ≥75 years admitted in the surgical ICU for a predicted length of stay ≥48 hours were included. Patients received an initial and a 6‐months nutritional and functional assessment performed by physicians and nurses. The outcome was considered as favourable if the Katz Activities of Daily Living (ADL) variation (ADL delta = 6‐months ADL – ICU admission ADL) was between 0 and −0.5 point 6 months after ICU discharge and unfavourable if the ADL delta decreased by more than 0.5 points or if the patient had died 6 months after ICU discharge. Results: Fifty‐six patients—32 (57%) male—aged 79 [77; 83] y were included. ICU mortality was 19%; 6‐month mortality was 22%. Median ADL delta was −0.5 [−0.5–0] points. A low ADL score (P =.0438) and a low albumin level (P =.0213) at admission were the two independent factors associated with an unfavourable outcome. Conclusion: Mortality and loss of independence were high in this elderly population during and after their surgical ICU stay. The benefit of a systematic collaboration between intensive care specialists, ICU nurses, and geriatricians, to assess and manage nutritional and functional problems and to prevent a pejorative outcome in patients over 75 years old admitted in surgical ICU needs to be studied. Relevance to clinical practice: There should be systematic screening for objective markers of undernutrition and frailty on ICU admission of older patients as they are associated with a poor prognosis. [ABSTRACT FROM AUTHOR]
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- 2023
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18. Gender Differences in Professional Social Networks Use Among Critical Care Researchers
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Demailly, Zoe, primary, Brulard, Geoffroy, additional, Tamion, Fabienne, additional, Veber, Benoit, additional, Occhiali, Emilie, additional, and Clavier, Thomas, additional
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- 2022
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19. Conflit en situation de limitation ou d’arrêt de traitement en réanimation
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Michel, Fabrice, primary, Claudot, Frédérique, additional, Veber, Benoit, additional, Brunel, Elodie, additional, Gateau, Valérie, additional, Guibet Lafaye, Caroline, additional, Kandelman, Stanislas, additional, Lallemant, Florence, additional, Le Boudec, Anne, additional, Ledorze, Matthieu, additional, Muller, Laurent, additional, Nouette-Gaulain, Karine, additional, Perrigault, Pierre-François, additional, Rutter, Nadège, additional, Samain, Emmanuel, additional, Visquesnel, Gérald, additional, and Zilberstein, Luca, additional
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- 2022
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20. Characteristics and prognosis of bloodstream infection in patients with COVID-19 admitted in the ICU: an ancillary study of the COVID-ICU study
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Massart, Nicolas, Maxime, Virginie, Fillatre, Pierre, Razazi, Keyvan, Ferré, Alexis, Moine, Pierre, Legay, Francois, Voiriot, Guillaume, Amara, Marlene, Santi, Francesca, Nseir, Saad, Marque-Juillet, Stephanie, Bounab, Rania, Barbarot, Nicolas, Bruneel, Fabrice, Luyt, Charles-Edouard, Mercat, Alain, Asfar, Pierre, Beloncle, François, Demiselle, Julien, Pham, Tài, Pavot, Arthur, Monnet, Xavier, Richard, Christian, Demoule, Alexandre, Dres, Martin, Mayaux, Julien, Beurton, Alexandra, Daubin, Cédric, Descamps, Richard, Joret, Aurélie, Du Cheyron, Damien, Pene, Frédéric, Chiche, Jean-Daniel, Jozwiak, Mathieu, Jaubert, Paul, Fartoukh, Muriel, Teulier, Marion, Blayau, Clarisse, Bodenes, Laetitia, Ferriere, Nicolas, Auchabie, Johann, Le Meur, Anthony, Pignal, Sylvain, Mazzoni, Thierry, Quenot, Jean-Pierre, Andreu, Pascal, Roudau, Jean-Baptiste, Labruyère, Marie, Preau, Sébastien, Poissy, Julien, Mathieu, Daniel, Benhamida, Sarah, Paulet, Rémi, Roucaud, Nicolas, Thyrault, Martial, Daviet, Florence, Hraiech, Sami, Parzy, Gabriel, Sylvestre, Aude, Jochmans, Sébastien, Bouilland, Anne-Laure, Monchi, Mehran, Déserts, Marc Danguy Des, Mathais, Quentin, Rager, Gwendoline, Pasquier, Pierre, Reignier, Jean, Seguin, Amélie, Garret, Charlotte, Canet, Emmanuel, Dellamonica, Jean, Saccheri, Clément, Lombardi, Romain, Kouchit, Yanis, Jacquier, Sophie, Mathonnet, Armelle, Nay, Mai-Ahn, Runge, Isabelle, Martino, Frédéric, Flurin, Laure, Rolle, Amélie, Carles, Michel, Coudroy, Rémi, Thille, Arnaud, Frat, Jean-Pierre, Rodriguez, Maeva, Beuret, Pascal, Tientcheu, Audrey, Vincent, Arthur, Michelin, Florian, Tamion, Fabienne, Carpentier, Dorothée, Boyer, Déborah, Girault, Christophe, Gissot, Valérie, Ehrmann, Stéphan, Gandonniere, Charlotte Salmon, Elaroussi, Djlali, Delbove, Agathe, Fedun, Yannick, Huntzinger, Julien, Lebas, Eddy, Kisoka, Grâce, Grégoire, Céline, Marchetta, Stella, Lambermont, Bernard, Argaud, Laurent, Baudry, Thomas, Bertrand, Pierre-Jean, Dargent, Auguste, Guitton, Christophe, Chudeau, Nicolas, Landais, Mickaël, Darreau, Cédric, Ferre, Alexis, Gros, Antoine, Lacave, Guillaume, Neuville, Mathilde, Devaquet, Jérôme, Tachon, Guillaume, Gallo, Richard, Chelha, Riad, Galbois, Arnaud, Jallot, Anne, Lemoine, Ludivine Chalumeau, Kuteifan, Khaldoun, Pointurier, Valentin, Jandeaux, Louise-Marie, Mootien, Joy, Damoisel, Charles, Sztrymf, Benjamin, Schmidt, Matthieu, Combes, Alain, Chommeloux, Juliette, Luyt, Charles Edouard, Schortgen, Frédérique, Rusel, Leon, Jung, Camille, Gobert, Florent, Vimpere, Damien, Lamhaut, Lionel, Sauneuf, Bertrand, Charrrier, Liliane, Calus, Julien, Desmeules, Isabelle, Painvin, Benoît, Tadie, Jean-Marc, Castelain, Vincent, Michard, Baptiste, Herbrecht, Jean-Etienne, Baldacini, Mathieu, Weiss, Nicolas, Demeret, Sophie, Marois, Clémence, Rohaut, Benjamin, Moury, Pierre-Henri, Savida, Anne-Charlotte, Couadau, Emmanuel, Série, Mathieu, Alexandru, Nica, Bruel, Cédric, Fontaine, Candice, Garrigou, Sonia, Mahler, Juliette Courtiade, Leclerc, Maxime, Ramakers, Michel, Garçon, Pierre, Massou, Nicole, van Vong, Ly, Sen, Juliane, Lucas, Nolwenn, Chemouni, Franck, Stoclin, Annabelle, Avenel, Alexandre, Faure, Henri, Gentilhomme, Angélie, Ricome, Sylvie, Abraham, Paul, Monard, Céline, Textoris, Julien, Rimmele, Thomas, Montini, Florent, Lejour, Gabriel, Lazard, Thierry, Etienney, Isabelle, Kerroumi, Younes, Dupuis, Claire, Bereiziat, Marine, Coupez, Elisabeth, Thouy, François, Hoffmann, Clément, Donat, Nicolas, Chrisment, Anne, Blot, Rose-Marie, Kimmoun, Antoine, Jacquot, Audrey, Mattei, Matthieu, Levy, Bruno, Ravan, Ramin, Dopeux, Loïc, Liteaudon, Jean-Mathias, Roux, Delphine, Rey, Brice, Anghel, Radu, Schenesse, Deborah, Gevrey, Vincent, Castanera, Jermy, Petua, Philippe, Madeux, Benjamin, Hartman, Otto, Piagnerelli, Michael, Joosten, Anne, Noel, Cinderella, Biston, Patrick, Noel, Thibaut, Bouar, Gurvan, Boukhanza, Messabi, Demarest, Elsa, Bajolet, Marie-France, Charrier, Nathanaël, Quenet, Audrey, Zylberfajn, Cécile, Dufour, Nicolas, Mégarbane, Buno, Voicu, Sébastian, Deye, Nicolas, Malissin, Isabelle, Legay, François, Debarre, Matthieu, Delord, Bertrand, Laterrade, Thomas, Saghi, Tahar, Pujol, Wilfried, Cungi, Pierre Julien, Esnault, Pierre, Cardinale, Mickael, Ha, Vivien Hong Tuan, Fleury, Grégory, Brou, Marie-Ange, Zafimahazo, Daniel, Tran-Van, David, Avargues, Patrick, Carenco, Lisa, Robin, Nicolas, Ouali, Alexandre, Houdou, Lucie, Le Terrier, Christophe, Suh, Noémie, Primmaz, Steve, Pugin, Jérome, Weiss, Emmanuel, Gauss, Tobias, Moyer, Jean-Denis, Burtz, Catherine Paugam, La Combe, Béatrice, Smonig, Rolland, Violleau, Jade, Cailliez, Pauline, Chelly, Jonathan, Marchalot, Antoine, Saladin, Cécile, Bigot, Christelle, Fayolle, Pierre-Marie, Fatséas, Jules, Ibrahim, Amr, Resiere, Dabor, Hage, Rabih, Cholet, Clémentine, Cantier, Marie, Trouiler, Pierre, Montravers, Philippe, Lortat-Jacob, Brice, Tanaka, Sebastien, Dinh, Alexy Tran, Duranteau, Jacques, Harrois, Anatole, Dubreuil, Guillaume, Werner, Marie, Godier, Anne, Hamada, Sophie, Zlotnik, Diane, Nougue, Hélène, Mekontso-Dessap, Armand, Carteaux, Guillaume, de Prost, Nicolas, Mongardon, Nicolas, Lamraoui, Meriam, Alessandri, Claire, de Roux, Quentin, de Roquetaillade, Charles, Chousterman, Benjamin, Mebazaa, Alexandre, Gayat, Etienne, Garnier, Marc, Pardo, Emmanuel, Satre-Buisson, Lea, Gutton, Christophe, Yvin, Elise, Marcault, Clémence, Azoulay, Elie, Darmon, Michael, Oufella, Hafid Ait, Hariri, Geoffroy, Urbina, Tomas, Mazerand, Sandie, Heming, Nicholas, Annane, Djillali, Bouglé, Adrien, Omar, Edris, Lancelot, Aymeric, Begot, Emmanuelle, Plantefeve, Gaétan, Contou, Damien, Mentec, Hervé, Pajot, Olivier, Faguer, Stanislas, Cointault, Olivier, Lavayssiere, Laurence, Nogier, Marie-Béatrice, Jamme, Matthieu, Pichereau, Claire, Hayon, Jan, Outin, Hervé, Dépret, François, Coutrot, Maxime, Chaussard, Maité, Guillemet, Lucie, Goffin, Pierre, Thouny, Romain, Guntz, Julien, Jadot, Laurent, Persichini, Romain, Jean-Michel, Vanessa, Georges, Hugues, Caulier, Thomas, Pradel, Gaël, Hausermann, Marie-Hélène, Nguyen-Valat, Thi My Hue, Boudinaud, Michel, Vivier, Emmanuel, Rosseli, Sylvène, Bourdin, Gaël, Pommier, Christian, Vinclair, Marc, Poignant, Simon, Mons, Sandrine, Bougouin, Wulfran, Bruna, Franklin, Maestraggi, Quentin, Roth, Christian, Bitker, Laurent, Dhelft, François, Bonnet-Chateau, Justine, Filippelli, Mathilde, Morichau-Beauchant, Tristan, Thierry, Stéphane, Le Roy, Charlotte, Jouan, Mélanie Saint, Goncalves, Bruno, Mazeraud, Aurélien, Daniel, Matthieu, Sharshar, Tarek, Cadoz, Cyril, Gaci, Rostane, Gette, Sébastien, Louis, Guillaune, Sacleux, Sophe-Caroline, Ordan, Marie-Amélie, Cravoisy, Aurélie, Conrad, Marie, Courte, Guilhem, Gibot, Sébastien, Benzidi, Younès, Casella, Claudia, Serpin, Laurent, Setti, Jean-Lou, Besse, Marie-Catherine, Bourreau, Anna, Pillot, Jérôme, Rivera, Caroline, Vinclair, Camille, Robaux, Marie-Aline, Achino, Chloé, Delignette, Marie-Charlotte, Mazard, Tessa, Aubrun, Frédéric, Bouchet, Bruno, Frérou, Aurélien, Muller, Laura, Quentin, Charlotte, Degoul, Samuel, Stihle, Xavier, Sumian, Claude, Bergero, Nicoletta, Lanaspre, Bernard, Quintard, Hervé, Maiziere, Eve Marie, Egreteau, Pierre-Yves, Leloup, Guillaume, Berteau, Florin, Cottrel, Marjolaine, Bouteloup, Marie, Jeannot, Matthieu, Blanc, Quentin, Saison, Julien, Geneau, Isabelle, Grenot, Romaric, Ouchike, Abdel, Hazera, Pascal, Masse, Anne-Lyse, Demiri, Suela, Vezinet, Corinne, Baron, Elodie, Benchetrit, Deborah, Monsel, Antoine, Trebbia, Grégoire, Schaack, Emmanuelle, Lepecq, Raphaël, Bobet, Mathieu, Vinsonneau, Christophe, Dekeyser, Thibault, Delforge, Quentin, Rahmani, Imen, Vivet, Bérengère, Paillot, Jonathan, Hierle, Lucie, Chaignat, Claire, Valette, Sarah, Her, Benoït, Brunet, Jennifier, Page, Mathieu, Boiste, Fabienne, Collin, Anthony, Bavozet, Florent, Garin, Aude, Dlala, Mohamed, Mhamdi, Kais, Beilouny, Bassem, Lavalard, Alexandra, Perez, Severine, Veber, Benoit, Guitard, Pierre-Gildas, Gouin, Philippe, Lamacz, Anna, Plouvier, Fabienne, Delaborde, Bertrand, Kherchache, Aïssa, Chaalal, Amina, Ricard, Jean-Damien, Amouretti, Marc, Freita-Ramos, Santiago, Roux, Damien, Constantin, Jean-Michel, Assefi, Mona, Lecore, Marine, Selves, Agathe, Prevost, Florian, Lamer, Christian, Shi, Ruiying, Knani, Lyes, Floury, Sébastien Pili, Vettoretti, Lucie, Levy, Michael, Marsac, Lucile, Dauger, Stéphane, Guilmin-Crépon, Sophie, Winiszewski, Hadrien, Piton, Gael, Soumagne, Thibaud, Capellier, Gilles, Putegnat, Jean-Baptiste, Bayle, Frédérique, Perrou, Maya, Thao, Ghyslaine, Géri, Guillaume, Charron, Cyril, Repessé, Xavier, Vieillard-Baron, Antoine, Guilbart, Mathieu, Roger, Pierre-Alexandre, Hinard, Sébastien, Macq, Pierre-Yves, Chaulier, Kevin, Goutte, Sylvie, Chillet, Patrick, Pitta, Anaïs, Darjent, Barbara, Bruneau, Amandine, Lasocki, Sigismond, Leger, Maxime, Gergaud, Soizic, Lemarie, Pierre, Terzi, Nicolas, Schwebel, Carole, Dartevel, Anaïs, Galerneau, Louis-Marie, Diehl, Jean-Luc, Hauw-Berlemont, Caroline, Péron, Nicolas, Guérot, Emmanuel, Amoli, Abolfazl Mohebbi, Benhamou, Michel, Deyme, Jean-Pierre, Andremont, Olivier, Lena, Diane, Cady, Julien, Causeret, Arnaud, de la Chapelle, Arnaud, Cracco, Christophe, Rouleau, Stéphane, Schnell, David, Foucault, Camille, Lory, Cécile, Chapelle, Thibault, Bruckert, Vincent, Garcia, Julie, Sahraoui, Abdlazize, Abbosh, Nathalie, Bornstain, Caroline, Pernet, Pierre, Poirson, Florent, Pasem, Ahmed, Karoubi, Philippe, Poupinel, Virginie, Gauthier, Caroline, Bouniol, François, Feuchere, Philippe, Heron, Anne, Carreira, Serge, Emery, Malo, Le Floch, Anne Sophie, Giovannangeli, Luana, Herzog, Nicolas, Giacardi, Christophe, Baudic, Thibaut, Thill, Chloé, Lebbah, Said, Palmyre, Jessica, Tubach, Florence, Hajage, David, Bonnet, Nicolas, Ebstein, Nathan, Gaudry, Stéphane, Cohen, Yves, Noublanche, Julie, Lesieur, Olivier, Sément, Arnaud, Roca-Cerezo, Isabel, Pascal, Michel, Sma, Nesrine, Colin, Gwenhaël, Lacherade, Jean-Claude, Bionz, Gauthier, Maquigneau, Natacha, Bouzat, Pierre, Durand, Michel, Hérault, Marie-Christine, Payen, Jean-Francois, Centre hospitalier Saint-Brieuc, Hôpital Raymond Poincaré [Garches], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) (CARMAS), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-CHU Henri Mondor [Créteil], Centre Hospitalier de Versailles André Mignot (CHV), CHU Lille, Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut de cardiologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), INSERM UMRS-1144, Université Paris Cité, Réanimation Médicale et Toxicologique, Hôpital Lariboisière, COVID ICU Bacteremia Study Group on behalf of the COVID-ICU Investigators, CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Henri Mondor, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases [IHU ICAN], and Mégarbane, Bruno
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[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,RC86-88.9 ,Research ,Correction ,Medical emergencies. Critical care. Intensive care. First aid ,bacterial infections and mycoses ,Critical Care and Intensive Care Medicine ,[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,[SDV.TOX] Life Sciences [q-bio]/Toxicology ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,[SDV.TOX]Life Sciences [q-bio]/Toxicology ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,[SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,human activities - Abstract
Background Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring intensive care unit (ICU) have a high incidence of hospital-acquired infections; however, data regarding hospital acquired bloodstream infections (BSI) are scarce. We aimed to investigate risk factors and outcome of BSI in critically ill coronavirus infectious disease-19 (COVID-19) patients. Patients and methods We performed an ancillary analysis of a multicenter prospective international cohort study (COVID-ICU study) that included 4010 COVID-19 ICU patients. For the present analysis, only those with data regarding primary outcome (death within 90 days from admission) or BSI status were included. Risk factors for BSI were analyzed using Fine and Gray competing risk model. Then, for outcome comparison, 537 BSI-patients were matched with 537 controls using propensity score matching. Results Among 4010 included patients, 780 (19.5%) acquired a total of 1066 BSI (10.3 BSI per 1000 patients days at risk) of whom 92% were acquired in the ICU. Higher SAPS II, male gender, longer time from hospital to ICU admission and antiviral drug before admission were independently associated with an increased risk of BSI, and interestingly, this risk decreased over time. BSI was independently associated with a shorter time to death in the overall population (adjusted hazard ratio (aHR) 1.28, 95% CI 1.05–1.56) and, in the propensity score matched data set, patients with BSI had a higher mortality rate (39% vs 33% p = 0.036). BSI accounted for 3.6% of the death of the overall population. Conclusion COVID-19 ICU patients have a high risk of BSI, especially early after ICU admission, risk that increases with severity but not with corticosteroids use. BSI is associated with an increased mortality rate.
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- 2021
21. Benefits and risks of noninvasive oxygenation strategy in COVID-19: a multicenter, prospective cohort study (COVID-ICU) in 137 hospitals
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Schmidt, Matthieu, Demoule, Alexandre, Hajage, David, Pham, Tài, Combes, Alain, Dres, Martin, Lebbah, Said, Kimmoun, Antoine, Mercat, Alain, Beduneau, Gaëtan, Palmyre, Jessica, Prevost, Margot, Ricard, Jean-Damien, Ferré, Alexis, Fayolle, Pierre-Marie, Girault, Christophe, Pradel, Gael, Asfar, Pierre, Beloncle, François, Demiselle, Julien, Pavot, Arthur, Monnet, Xavier, Richard, Christian, Mayaux, Julien, Beurton, Alexandra, Daubin, Cédric, Descamps, Richard, Joret, Aurélie, Du Cheyron, Damien, Pene, Frédéric, Chiche, Jean-Daniel, Jozwiak, Mathieu, Jaubert, Paul, Voiriot, Guillaume, Fartoukh, Muriel, Teulier, Marion, Blayau, Clarisse, L’her, Erwen, Aubron, Cécile, Bodenes, Laetitia, Ferriere, Nicolas, Auchabie, Johann, Le Meur, Anthony, Pignal, Sylvain, Mazzoni, Thierry, Quenot, Jean-Pierre, Andreu, Pascal, Roudau, Jean-Baptiste, Labruyère, Marie, Nseir, Saad, Preau, Sébastien, Poissy, Julien, Mathieu, Daniel, Benhamida, Sarah, Paulet, Rémi, Roucaud, Nicolas, Thyrault, Martial, Daviet, Florence, Hraiech, Sami, Parzy, Gabriel, Sylvestre, Aude, Jochmans, Sébastien, Bouilland, Anne-Laure, Monchi, Mehran, Des Déserts, Marc Danguy, Mathais, Quentin, Rager, Gwendoline, Pasquier, Pierre, Jean, Reignier, Amélie, Seguin, Charlotte, Garret, Emmanuel, Canet, Dellamonica, Jean, Saccheri, Clément, Lombardi, Romain, Kouchit, Yanis, Jacquier, Sophie, Mathonnet, Armelle, Nay, Mai-Ahn, Runge, Isabelle, Martino, Frédéric, Flurin, Laure, Rolle, Amélie, Carles, Michel, Coudroy, Rémi, Thille, Arnaud, Frat, Jean-Pierre, Rodriguez, Maeva, Beuret, Pascal, Tientcheu, Audrey, Vincent, Arthur, Michelin, Florian, Tamion, Fabienne, Carpentier, Dorothée, Boyer, Déborah, Gissot, Valérie, Ehrmann, Stéphan, Gandonniere, Charlotte Salmon, Elaroussi, Djlali, Delbove, Agathe, Fedun, Yannick, Huntzinger, Julien, Lebas, Eddy, Kisoka, Grâce, Grégoire, Céline, Marchetta, Stella, Lambermont, Bernard, Argaud, Laurent, Baudry, Thomas, Bertrand, Pierre-Jean, Dargent, Auguste, Guitton, Christophe, Chudeau, Nicolas, Landais, Mickaël, Darreau, Cédric, Ferre, Alexis, Gros, Antoine, Lacave, Guillaume, Bruneel, Fabrice, Neuville, Mathilde, Devaquet, Jérôme, Tachon, Guillaume, Gallot, Richard, Chelha, Riad, Galbois, Arnaud, Jallot, Anne, Lemoine, Ludivine Chalumeau, Kuteifan, Khaldoun, Pointurier, Valentin, Jandeaux, Louise-Marie, Mootien, Joy, Damoisel, Charles, Sztrymf, Benjamin, Chommeloux, Juliette, Luyt, Charles Edouard, Schortgen, Frédérique, Rusel, Leon, Jung, Camille, Gobert, Florent, Vimpere, Damien, Lamhaut, Lionel, Sauneuf, Bertrand, Charrrier, Liliane, Calus, Julien, Desmeules, Isabelle, Painvin, Benoît, Tadie, Jean-Marc, Castelain, Vincent, Michard, Baptiste, Herbrecht, Jean-Etienne, Baldacini, Mathieu, Weiss, Nicolas, Demeret, Sophie, Marois, Clémence, Rohaut, Benjamin, Moury, Pierre-Henri, Savida, Anne-Charlotte, Couadau, Emmanuel, Série, Mathieu, Alexandru, Nica, Bruel, Cédric, Fontaine, Candice, Garrigou, Sonia, Mahler, Juliette Courtiade, Leclerc, Maxime, Ramakers, Michel, Garçon, Pierre, Massou, Nicole, van Vong, Ly, Sen, Juliane, Lucas, Nolwenn, Chemouni, Franck, Stoclin, Annabelle, Avenel, Alexandre, Faure, Henri, Gentilhomme, Angélie, Ricome, Sylvie, Abraham, Paul, Monard, Céline, Textoris, Julien, Rimmele, Thomas, Montini, Florent, Lejour, Gabriel, Lazard, Thierry, Etienney, Isabelle, Kerroumi, Younes, Dupuis, Claire, Bereiziat, Marine, Coupez, Elisabeth, Thouy, François, Hoffmann, Clément, Donat, Nicolas, Chrisment, Anne, Blot, Rose-Marie, Jacquot, Audrey, Mattei, Matthieu, Levy, Bruno, Ravan, Ramin, Dopeux, Loïc, Liteaudon, Jean-Mathias, Roux, Delphine, Rey, Brice, Anghel, Radu, Schenesse, Deborah, Gevrey, Vincent, Castanera, Jermy, Petua, Philippe, Madeux, Benjamin, Hartman, Otto, Piagnerelli, Michael, Joosten, Anne, Noel, Cinderella, Biston, Patrick, Noel, Thibaut, Bouar, Gurvan, Boukhanza, Messabi, Demarest, Elsa, Bajolet, Marie-France, Charrier, Nathanaël, Quenet, Audrey, Zylberfajn, Cécile, Dufour, Nicolas, Mégarbane, Buno, Voicu, Sqébastian, Deye, Nicolas, Malissin, Isabelle, Legay, François, Debarre, Matthieu, Barbarot, Nicolas, Fillatre, Pierre, Delord, Bertrand, Laterrade, Thomas, Saghi, Tahar, Pujol, Wilfried, Cungi, Pierre Julien, Esnault, Pierre, Cardinale, Mickael, Ha, Vivien Hong Tuan, Fleury, Grégory, Brou, Marie-Ange, Zafimahazo, Daniel, Tran-Van, David, Avargues, Patrick, Carenco, Lisa, Robin, Nicolas, Ouali, Alexandre, Houdou, Lucie, Le Terrier, Christophe, Suh, Noémie, Primmaz, Steve, Pugin, Jérome, Weiss, Emmanuel, Gauss, Tobias, Moyer, Jean-Denis, Burtz, Catherine Paugam, La Combe, Béatrice, Smonig, Rolland, Violleau, Jade, Cailliez, Pauline, Chelly, Jonathan, Marchalot, Antoine, Saladin, Cécile, Bigot, Christelle, Fatséas, Jules, Ibrahim, Amr, Resiere, Dabor, Hage, Rabih, Cholet, Clémentine, Cantier, Marie, Trouiler, Pierre, Montravers, Philippe, Lortat-Jacob, Brice, Tanaka, Sebastien, Dinh, Alexy Tran, Duranteau, Jacques, Harrois, Anatole, Dubreuil, Guillaume, Werner, Marie, Godier, Anne, Hamada, Sophie, Zlotnik, Diane, Nougue, Hélène, Mekontso-Dessap, Armand, Carteaux, Guillaume, Razazi, Keyvan, de Prost, Nicolas, Mongardon, Nicolas, Langeron, Olivier, Levesque, Eric, Attias, Arié, de Roquetaillade, Charles, Chousterman, Benjamin, Mebazaa, Alexandre, Gayat, Etienne, Garnier, Marc, Pardo, Emmanuel, Satre-Buisson, Lea, Gutton, Christophe, Yvin, Elise, Marcault, Clémence, Azoulay, Elie, Darmon, Michael, Oufella, Hafid Ait, Hariri, Geoffroy, Urbina, Tomas, Mazerand, Sandie, Heming, Nicholas, Santi, Francesca, Moine, Pierre, Annane, Djillali, Bouglé, Adrien, Omar, Edris, Lancelot, Aymeric, Begot, Emmanuelle, Plantefeve, Gaétan, Contou, Damien, Mentec, Hervé, Pajot, Olivier, Faguer, Stanislas, Cointault, Olivier, Lavayssiere, Laurence, Nogier, Marie-Béatrice, Jamme, Matthieu, Pichereau, Claire, Hayon, Jan, Outin, Hervé, Dépret, François, Coutrot, Maxime, Chaussard, Maité, Guillemet, Lucie, Goffin, Pierre, Thouny, Romain, Guntz, Julien, Jadot, Laurent, Persichini, Romain, Jean-Michel, Vanessa, Georges, Hugues, Caulier, Thomas, Pradel, Gaël, Hausermann, Marie-Hélène, Nguyen-Valat, Thi My Hue, Boudinaud, Michel, Vivier, Emmanuel, Rosseli, Sylvène, Bourdin, Gaël, Pommier, Christian, Vinclair, Marc, Poignant, Simon, Mons, Sandrine, Bougouin, Wulfran, Bruna, Franklin, Maestraggi, Quentin, Roth, Christian, Bitker, Laurent, Dhelft, François, Bonnet-Chateau, Justine, Filippelli, Mathilde, Morichau-Beauchant, Tristan, Thierry, Stéphane, Le Roy, Charlotte, Jouan, Mélanie Saint, Goncalves, Bruno, Mazeraud, Aurélien, Daniel, Matthieu, Sharshar, Tarek, Cadoz, Cyril, Gaci, Rostane, Gette, Sébastien, Louis, Guillaune, Sacleux, Sophe-Caroline, Ordan, Marie-Amélie, Cravoisy, Aurélie, Conrad, Marie, Courte, Guilhem, Gibot, Sébastien, Benzidi, Younès, Casella, Claudia, Serpin, Laurent, Setti, Jean-Lou, Besse, Marie-Catherine, Bourreau, Anna, Pillot, Jérôme, Rivera, Caroline, Vinclair, Camille, Robaux, Marie-Aline, Achino, Chloé, Delignette, Marie-Charlotte, Mazard, Tessa, Aubrun, Frédéric, Bouchet, Bruno, Frérou, Aurélien, Muller, Laura, Quentin, Charlotte, Degoul, Samuel, Stihle, Xavier, Sumian, Claude, Bergero, Nicoletta, Lanaspre, Bernard, Quintard, Hervé, Maiziere, Eve Marie, Egreteau, Pierre-Yves, Leloup, Guillaume, Berteau, Florin, Cottrel, Marjolaine, Bouteloup, Marie, Jeannot, Matthieu, Blanc, Quentin, Saison, Julien, Geneau, Isabelle, Grenot, Romaric, Ouchike, Abdel, Hazera, Pascal, Masse, Anne-Lyse, Demiri, Suela, Vezinet, Corinne, Baron, Elodie, Benchetrit, Deborah, Monsel, Antoine, Trebbia, Grégoire, Schaack, Emmanuelle, Lepecq, Raphaël, Bobet, Mathieu, Vinsonneau, Christophe, Dekeyser, Thibault, Delforge, Quentin, Rahmani, Imen, Vivet, Bérengère, Paillot, Jonathan, Hierle, Lucie, Chaignat, Claire, Valette, Sarah, Her, Benoït, Brunet, Jennifier, Page, Mathieu, Boiste, Fabienne, Collin, Anthony, Bavozet, Florent, Garin, Aude, Dlala, Mohamed, Mhamdi, Kais, Beilouny, Bassem, Lavalard, Alexandra, Perez, Severine, Veber, Benoit, Guitard, Pierre-Gildas, Gouin, Philippe, Lamacz, Anna, Plouvier, Fabienne, Delaborde, Bertrand, Kherchache, Aïssa, Chaalal, Amina, Amouretti, Marc, Freita-Ramos, Santiago, Roux, Damien, Constantin, Jean-Michel, Assefi, Mona, Lecore, Marine, Selves, Agathe, Prevost, Florian, Lamer, Christian, Shi, Ruiying, Knani, Lyes, Floury, Sébastien Pili, Vettoretti, Lucie, Levy, Michael, Marsac, Lucile, Dauger, Stéphane, Guilmin-Crépon, Sophie, Winiszewski, Hadrien, Piton, Gael, Soumagne, Thibaud, Capellier, Gilles, Putegnat, Jean-Baptiste, Bayle, Frédérique, Perrou, Maya, Thao, Ghyslaine, Géri, Guillaume, Charron, Cyril, Repessé, Xavier, Vieillard-Baron, Antoine, Guilbart, Mathieu, Roger, Pierre-Alexandre, Hinard, Sébastien, Macq, Pierre-Yves, Chaulier, Kevin, Goutte, Sylvie, Chillet, Patrick, Pitta, Anaïs, Darjent, Barbara, Bruneau, Amandine, Lasocki, Sigismond, Leger, Maxime, Gergaud, Soizic, Lemarie, Pierre, Terzi, Nicolas, Schwebel, Carole, Dartevel, Anaïs, Galerneau, Louis-Marie, Diehl, Jean-Luc, Hauw-Berlemont, Caroline, Péron, Nicolas, Guérot, Emmanuel, Amoli, Abolfazl Mohebbi, Benhamou, Michel, Deyme, Jean-Pierre, Andremont, Olivier, Lena, Diane, Cady, Julien, Causeret, Arnaud, de la Chapelle, Arnaud, Cracco, Christophe, Rouleau, Stéphane, Schnell, David, Foucault, Camille, Lory, Cécile, Chapelle, Thibault, Bruckert, Vincent, Garcia, Julie, Sahraoui, Abdlazize, Abbosh, Nathalie, Bornstain, Caroline, Pernet, Pierre, Poirson, Florent, Pasem, Ahmed, Karoubi, Philippe, Poupinel, Virginie, Gauthier, Caroline, Bouniol, François, Feuchere, Philippe, Heron, Anne, Carreira, Serge, Emery, Malo, Le Floch, Anne Sophie, Giovannangeli, Luana, Herzog, Nicolas, Giacardi, Christophe, Baudic, Thibaut, Thill, Chloé, Tubach, Florence, Bonnet, Nicolas, Ebstein, Nathan, Gaudry, Stéphane, Cohen, Yves, Noublanche, Julie, Lesieur, Olivier, Sément, Arnaud, Roca-Cerezo, Isabel, Pascal, Michel, Sma, Nesrine, Colin, Gwenhaël, Lacherade, Jean-Claude, Bionz, Gauthier, Maquigneau, Natacha, Bouzat, Pierre, Durand, Michel, Hérault, Marie-Christine, Payen, Jean-Francois, Service de Réanimation Médicale et Toxicologique [Hôpital Lariboisière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), COVID-ICU group, for the REVA network, COVID-ICU investigators, and Mégarbane, Bruno
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Critical Care and Intensive Care Medicine ,Acute respiratory failure ,[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,Risk Assessment ,Mechanical ventilation ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Humans ,Prospective Studies ,Mortality ,Outcome ,[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,Noninvasive Ventilation ,Acute respiratory distress syndrome ,RC86-88.9 ,Research ,COVID-19 ,Medical emergencies. Critical care. Intensive care. First aid ,Hospitals ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,[SDV.TOX] Life Sciences [q-bio]/Toxicology ,Intensive Care Units ,[SDV.TOX]Life Sciences [q-bio]/Toxicology ,High-flow nasal cannula ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,[SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,Intubation - Abstract
Rational To evaluate the respective impact of standard oxygen, high-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) on oxygenation failure rate and mortality in COVID-19 patients admitted to intensive care units (ICUs). Methods Multicenter, prospective cohort study (COVID-ICU) in 137 hospitals in France, Belgium, and Switzerland. Demographic, clinical, respiratory support, oxygenation failure, and survival data were collected. Oxygenation failure was defined as either intubation or death in the ICU without intubation. Variables independently associated with oxygenation failure and Day-90 mortality were assessed using multivariate logistic regression. Results From February 25 to May 4, 2020, 4754 patients were admitted in ICU. Of these, 1491 patients were not intubated on the day of ICU admission and received standard oxygen therapy (51%), HFNC (38%), or NIV (11%) (P P P = 0.013) but not NIV (OR 1.57, 95% CI 0.78–3.21) was associated with a reduction in oxygenation failure). Overall 90-day mortality was 21%. By multivariable analysis, HFNC was not associated with a change in mortality (OR 0.90, 95% CI 0.61–1.33), while NIV was associated with increased mortality (OR 2.75, 95% CI 1.79–4.21, P Conclusion In patients with COVID-19, HFNC was associated with a reduction in oxygenation failure without improvement in 90-day mortality, whereas NIV was associated with a higher mortality in these patients. Randomized controlled trials are needed.
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- 2021
22. Dynamic metabolic changes measured by indirect calorimetry during the early phase of septic shock: a prospective observational pilot study
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Occhiali, Emilie, primary, Urli, Maximilien, additional, Pressat-Laffouilhère, Thibaut, additional, Achamrah, Najate, additional, Veber, Benoit, additional, and Clavier, Thomas, additional
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- 2021
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23. The Association Between Professional Accounts on Social Networks Twitter and ResearchGate and the Number of Scientific Publications and Citations Among Anesthesia Researchers: Observational Study
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Clavier, Thomas, primary, Occhiali, Emilie, additional, Demailly, Zoé, additional, Compère, Vincent, additional, Veber, Benoit, additional, Selim, Jean, additional, and Besnier, Emmanuel, additional
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- 2021
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24. Risk factors for therapeutic failure in the management of post-operative peritonitis: a post hoc analysis of the DURAPOP trial.
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Montravers, Philippe, Esposito-Farèse, Marina, Lasocki, Sigismond, Grall, Nathalie, Veber, Benoit, Eloy, Philippine, Seguin, Philippe, Weiss, Emmanuel, Dupont, Herve, group, the DURAPOP trial, and DURAPOP trial group
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POSTOPERATIVE care ,THERAPEUTIC complications ,PERITONITIS ,PREOPERATIVE risk factors ,RENAL replacement therapy ,COMORBIDITY ,ANTIBIOTICS ,RESEARCH ,RESEARCH methodology ,EVALUATION research ,PENICILLIN ,COMPARATIVE studies ,RANDOMIZED controlled trials ,AMPICILLIN ,RESEARCH funding ,LONGITUDINAL method - Abstract
Background: Therapeutic failure is a frequent issue in the management of post-operative peritonitis.Objectives: A post hoc analysis of the prospective, multicentre DURAPOP trial analysed the risk factors for failures in post-operative peritonitis following adequate source control and empirical antibiotic therapy in critically ill patients.Patients and Methods: Overall failures assessed post-operatively between Day 8 and Day 45 were defined as a composite of death and/or surgical and/or microbiological failures. Risk factors for failures were assessed using logistic regression analyses.Results: Among the 236 analysed patients, overall failures were reported in 141 (59.7%) patients, including 30 (12.7%) deaths, 81 (34.3%) surgical and 95 (40.2%) microbiological failures. In the multivariate analysis, the risk factors associated with overall failures were documented piperacillin/tazobactam therapy [adjusted OR (aOR) 2.10; 95% CI 1.17-3.75] and renal replacement therapy on the day of reoperation (aOR 2.96; 95% CI 1.05-8.34). The risk factors for death were age (aOR 1.08 per year; 95% CI 1.03-1.12), renal replacement therapy on reoperation (aOR 3.95; 95% CI 1.36-11.49) and diabetes (OR 6.95; 95% CI 1.34-36.03). The risk factors associated with surgical failure were documented piperacillin/tazobactam therapy (aOR 1.99; 95% CI 1.13-3.51), peritoneal cultures containing Klebsiella spp. (aOR 2.45; 95% CI 1.02-5.88) and pancreatic source of infection (aOR 2.91; 95% CI 1.21-7.01). No specific risk factors were identified for microbiological failure.Conclusions: Our data suggest a predominant role of comorbidities, the severity of post-operative peritonitis and possibly of documented piperacillin/tazobactam treatment on the occurrence of therapeutic failures, regardless of their type. [ABSTRACT FROM AUTHOR]- Published
- 2021
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25. Effect of early hyperoxemia on mortality in mechanically ventilated septic shock patients according to Sepsis-3 criteria: analysis of the MIMIC-III database.
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Popoff, Benjamin, Besnier, Emmanuel, Dureuil, Bertrand, Veber, Benoit, and Clavier, Thomas
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- 2021
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26. Intérêt des publications scientifiques pour la carrière universitaire
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Tavernier, Benoit and Veber, Benoit
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- 2024
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27. Vincent Laudenbach (1968-2022)
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Veber, Benoît
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- 2023
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