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Several studies have looked into the effectiveness of bleomycin treatment for warts using various injection methods, such as intralesional injection, multiple puncture technique, jet injection, and moonlet needle prick method, in various concentrations and doses. However, injection methods have been linked to acute pain and bleeding. The purpose of this study is to examine the efficacy of microneedling combination with topical bleomycin and cryotherapy in the treatment of resistant warts on the hands and feet. This randomized clinical trial, conducted at Sina Hospital in Tabriz, involved 90 patients with treatment-resistant warts on their hands and feet. Treatment measures were repeated every two weeks in treatment-resistant patients who did not react to four cryotherapy sessions or whose lesions remained stable for six months. Each wart lesion was randomly assigned to one of two treatment groups: topical bleomycin with microneedling or cryotherapy. The effectiveness of the treatment in weeks 2, 4, 6, and 8 with PGA and PaGA, the amount of clearance, and side effects were evaluated in each session and the 8th week. Pain during therapy was assessed using a visual analog scale (VAS) ranging from 0 to 10. The patients’ mean age was 33.65 ± 12.24 years, with 63.3% being female. A total of 186 resistant wart lesions were treated, with 98 (52.7%) situated in the palmar region and 88 (47.3%) in the plantar region. In palm lesions, the bleomycin micro-needling group had a considerably greater clearance rate than the cryotherapy group (86.4% vs. 61.9%; p = 0.001). In foot lesions, the bleomycin microneedling group had a greater clearance rate than the cryotherapy group, although there was no statistically significant difference (69.6% vs. 54.2%; p = 0.209). In the eighth week following the intervention, the number of lesions and the diameter of warts on the palms and feet decreased significantly in the bleomycin microneedling group when compared to the cryotherapy group. Bleomycin microneedling had no adverse effects; however, in patients undergoing cryotherapy, local pain, blisters, and scars were noted. Bleomycin microneedling has a higher therapeutic efficiency than cryotherapy for treating refractory hand and foot warts, and it removes lesions more effectively. In addition, this therapeutic method is safer and has fewer side effects than cryotherapy. [ABSTRACT FROM AUTHOR]

Background & Objective: Aligning faculty members' learning styles with their teaching approaches is a complicated topic in education. Understanding these inclinations can help enhance pedagogical practices and build a more inclusive learning environment. Thus, this study examined the relationship between learning style preferences and teaching technique choices among Iranian faculty members. Material & Methods: From May to July 2022, a cross-sectional online survey was conducted among faculty members at Iranian medical universities via the Porsline website. Virtual snowball sampling was used to recruit 526 individuals. The VARK questionnaire was translated into Persian and showed excellent reliability, with a Cronbach's alpha of 0.94. The final data collection tools included the translated VARK questionnaire, self-assessment questions about teaching methods, university resources, and digital media center equipment. Analytical methods included descriptive statistics, logistic regression analysis, and chi-square testing for data evaluation. Results: The survey found that clinical teachers preferred reading and writing (54%), whereas fundamental science educators preferred visual-auditory and reading-writing. The effect of gender, field of study, learning style, age, and professional academic factors on the dependent variable, teaching method, was investigated using chi-square tests and logistic regression. The findings revealed that while there was no significant relationship between the variable gender and teaching method, significant associations were found with the variables field of study, learning style, age, and professional academic. Notably, it was observed that the effect size of field of study, age, and professional academic on teaching method is small, while for learning style, it is medium in magnitude. Conclusion: The study uncovers a significant correlation between learning styles and teaching methods, suggesting that their learning backgrounds may shape teachers' teaching methods. [ABSTRACT FROM AUTHOR]

Several studies have looked into the effectiveness of bleomycin treatment for warts using various injection methods, such as intralesional injection, multiple puncture technique, jet injection, and moonlet needle prick method, in various concentrations and doses. However, injection methods have been linked to acute pain and bleeding. The purpose of this study is to examine the efficacy of microneedling combination with topical bleomycin and cryotherapy in the treatment of resistant warts on the hands and feet. This randomized clinical trial, conducted at Sina Hospital in Tabriz, involved 90 patients with treatment-resistant warts on their hands and feet. Treatment measures were repeated every two weeks in treatment-resistant patients who did not react to four cryotherapy sessions or whose lesions remained stable for six months. Each wart lesion was randomly assigned to one of two treatment groups: topical bleomycin with microneedling or cryotherapy. The effectiveness of the treatment in weeks 2, 4, 6, and 8 with PGA and PaGA, the amount of clearance, and side effects were evaluated in each session and the 8th week. Pain during therapy was assessed using a visual analog scale (VAS) ranging from 0 to 10. The patients' mean age was 33.65 ± 12.24 years, with 63.3% being female. A total of 186 resistant wart lesions were treated, with 98 (52.7%) situated in the palmar region and 88 (47.3%) in the plantar region. In palm lesions, the bleomycin micro-needling group had a considerably greater clearance rate than the cryotherapy group (86.4% vs. 61.9%; p = 0.001). In foot lesions, the bleomycin microneedling group had a greater clearance rate than the cryotherapy group, although there was no statistically significant difference (69.6% vs. 54.2%; p = 0.209). In the eighth week following the intervention, the number of lesions and the diameter of warts on the palms and feet decreased significantly in the bleomycin microneedling group when compared to the cryotherapy group. Bleomycin microneedling had no adverse effects; however, in patients undergoing cryotherapy, local pain, blisters, and scars were noted. Bleomycin microneedling has a higher therapeutic efficiency than cryotherapy for treating refractory hand and foot warts, and it removes lesions more effectively. In addition, this therapeutic method is safer and has fewer side effects than cryotherapy., Competing Interests: Declarations. Ethical approval: This study was approved by the Ethics Committee of Tabriz University of Medical Sciences, following the ethical principles of the Helsinki Declaration and Good Clinical Practices (Protocol number, IR.TBZMED.REC.1401.1004, and was prospectively registered at IRCT.ir, clinical trials registry, with identifier number: IRCT20221109056452N1). Competing interests: The authors declare no competing interests., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)