Search

Your search keyword '"Valim, Valéria"' showing total 43 results
Start Over Author "Valim, Valéria" Publication Year Range Last 3 years
43 results on '"Valim, Valéria"'

2. Half dose ChAdOx1 nCoV-19 vaccine was equivalent to full doses to reduce moderate and severe COVID-19 cases

Author

Galvão-Lima, Leonardo J., de Medeiros Júnior, Nésio Fernandes, Jesus, Galileu S., Morais, Antônio H.F., Caldeira-Silva, Gleyson J.P., Queiroz dos Santos, João Paulo, Rocha, Marcella, Marques dos Santos, Marquiony, Freire, Pierre A., Silva, Rodrigo D., Gouvea, Maria da Penha Gomes, Neto, Lauro Ferreira Pinto, Domingues, Carla Magda Allan Santos, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Valim, Valéria, and Valentim, Ricardo A.M.

Published
2023
Full Text
View/download PDF

3. Timeline kinetics of protective immunity to SARS-CoV-2 upon primary vaccination and humoral response to variants after booster dose

Author

da Penha Gomes Gouvea, Maria, Lira Machado, Ketty Lysie Libardi, de Oliveira, Yasmin Gurtler Pinheiro, Moulaz, Isac Ribeiro, Henriques, Allan Gonçalves, Gouveia, Thayná Martins, Thompson, Beatriz Paoli, Lança, Karen Evelin Monlevade, de Souza Ramos, Sabrina, Lacerda, Gabriela Curto Cristianes, Lenzi, João Pedro Gonçalves, de Castro Pimentel, Felipe, Miossi, João Pedro Moraes, Rassele, Matheus Leite, Camacho, Luiz Antônio Bastos, Villela, Daniel Antunes Maciel, de Lima, Sheila Maria Barbosa, de Souza Azevedo, Adriana, Horbach, Ingrid Siciliano, de Araújo, Mia Ferreira, Tort, Luis Fernando Lopez, de Oliveira, Any Caroline Alves, Siqueira, Marilda Mendonça, Garcia, Cristiana Couto, da Costa-Rocha, Ismael Artur, Campi-Azevedo, Ana Carolina, Peruhype-Magalhães, Vanessa, da Silva, Vanézia Gonçalves, Miyamoto, Samira Tatiyama, dos Santos Fantoni, Rosilene Nilo, Pinto-Neto, Lauro Ferreira, Magda Domingues, Carla, de Medeiros Junior, Nésio Fernandes, Burian, Ana Paula, Teixeira-Carvalho, Andréa, Mota, Licia Maria Henrique, Mill, José Geraldo, Martins-Filho, Olindo Assis, and Valim, Valéria

Published
2023
Full Text
View/download PDF

4. Serum soluble mediators as prognostic biomarkers for morbidity, disease outcome, and late-relapsing hepatitis in yellow fever patients

Author

Fradico, Jordana Rodrigues Barbosa, Campi-Azevedo, Ana Carolina, Speziali, Elaine, do Valle Antonelli, Lis Ribeiro, Peruhype-Magalhães, Vanessa, de Rezende, Izabela Maurício, Alves, Pedro Augusto, Pascoal-Xavier, Marcelo Antônio, Pereira, Leonardo Soares, Dutra, Maria Rita Teixeira, Ramalho, Dario Brock, Cenachi, Adriana, de Paula, Ludmila, Santos, Tayrine Araujo, do Carmo Said, Rodrigo Fabiano, Calzavara-Silva, Carlos Eduardo, Coelho-dos-Reis, Jordana Grazziela Alves, de Magalhães, Clara Ramos, Rabelo, Lara Luíza Cerávolo, Valim, Valéria, Brito-de-Sousa, Joaquim Pedro, da Costa-Rocha, Ismael Artur, de Souza Gomes, Matheus, Amaral, Laurence Rodrigues, de Lima, Sheila Maria Barbosa, Trindade, Gisela Freitas, Santos, Renata Tourinho, da Silva, Juliana Fernandes Amorim, Monath, Thomas, LaBeaud, Angelle Desiree, Drumond, Betânia Paiva, Martins-Filho, Olindo Assis, and Teixeira-Carvalho, Andréa

Published
2023
Full Text
View/download PDF

5. Brazilian version of the “Primary Sjögren’s Syndrome - Quality of Life questionnaire (PSS-QoL)”: translation, cross-cultural adaptation and validation

Author

Miyamoto, Samira Tatiyama, primary, Serrano, Érica Vieira, additional, Gianórdoli, Ana Paula Espíndula, additional, Altoé, Lara Betini, additional, Noronha, Bianca Domingos, additional, Santos, Pedro Henrique Alves dos, additional, Pedrini, Ana Paula Truhlar, additional, Silva, Nicole Reis Souza da, additional, Favarato, Letícia Fonseca, additional, Alochio, Luíza Vallory, additional, Tomé, Weider Andrade, additional, Lackner, Angelika, additional, and Valim, Valéria, additional

Published
2024
Full Text
View/download PDF

6. Predictors of Hospitalization in Breakthrough COVID-19 among Fully Vaccinated Individuals with Immune-Mediated Rheumatic Diseases: Data from SAFER-Study.

Author

Calderaro, Débora Cerqueira, Valim, Valéria, Ferreira, Gilda Aparecida, Machado, Ketty Lysie Libardi Lira, Ribeiro, Priscila Dias Cardoso, Ribeiro, Sandra Lúcia Euzébio, Sartori, Natalia Sarzi, de Rezende, Rodrigo Poubel Vieira, de Melo, Ana Karla Guedes, Cruz, Vitor Alves, Vieira, Adah Sophia Rodrigues, Kakehasi, Adriana Maria, de Landa, Aline Teixeira, Burian, Ana Paula Neves, Peixoto, Flávia Maria Matos Melo Campos, Telles, Camila Maria Paiva França, do Espírito Santo, Rafaela Cavalheiro, Baptista, Katia Lino, de Oliveira, Yasmin Gurtler Pinheiro, and Magalhães, Vanessa de Oliveira

Subjects
BOOSTER vaccines, BREAKTHROUGH infections, COVID-19 vaccines, RHEUMATISM, VACCINE immunogenicity
Abstract

Breakthrough COVID-19 (occurring in fully vaccinated people) has been described. Data on its characteristics among immune-mediated rheumatic disease (IMRD) patients are scarce. This study describes breakthrough COVID-19 occurring in IMRD patients participating in the SAFER-study, a Brazilian multicentric cohort evaluating the safety, effectiveness, and immunogenicity of SARS-CoV-2 vaccines in patients with autoimmune diseases. A descriptive analysis of the population and a binary logistic regression model were performed to evaluate the predictors of COVID-19-related hospitalization. A p-value < 0.05 was significant. The included 160 patients were predominantly females (83.1%), with a mean (SD) age of 40.23 (13.19) years. The patients received two (19%), three (70%), or four (11%) vaccine doses. The initial two-dose series was mainly with ChAdOx1 (Oxford/AstraZeneca) (58%) or BBIBP-CorV (Sinopharm-Beijing) (34%). The first booster (n = 150) was with BNT162b2 (BioNtech/Fosun Pharma/Pfizer) (63%) or ChAdOx1 (29%). The second booster (n = 112) was with BNT162b2 (40%) or ChAdOx1 (26%). The COVID-19 hospitalization rate was 17.5%. IMRD moderate/high activity (OR: 5.84; CI: 1.9–18.5; p = 0.002) and treatment with corticosteroids (OR: 2.94; CI: 1.02–8.49; p = 0.0043) were associated with higher odds of hospitalization, while increasing the number of vaccine doses was protective (OR: 0.37; CI: 0.15–0.9; p = 0.032). These findings, along with previous reassuring results about the safety of the COVID-19 vaccines, argue in favor of booster vaccination in IMRD patients. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

7. Brazilian version of the "Primary Sjögren's Syndrome - Quality of Life questionnaire (PSS-QoL)": translation, cross-cultural adaptation and validation.

Author

Miyamoto, Samira Tatiyama, Serrano, Érica Vieira, Gianórdoli, Ana Paula Espíndula, Altoé, Lara Betini, Noronha, Bianca Domingos, dos Santos, Pedro Henrique Alves, Pedrini, Ana Paula Truhlar, da Silva, Nicole Reis Souza, Favarato, Letícia Fonseca, Alochio, Luíza Vallory, Tomé, Weider Andrade, Lackner, Angelika, and Valim, Valéria

Published
2024
Full Text
View/download PDF

8. Plaque Reduction Neutralization Test (PRNT) Accuracy in Evaluating Humoral Immune Response to SARS-CoV-2

Author

Horbach, Ingrid Siciliano, primary, de Souza Azevedo, Adriana, additional, Schwarcz, Waleska Dias, additional, Alves, Nathalia dos Santos, additional, de Moura Dias, Brenda, additional, Setatino, Bruno Pimenta, additional, da Cruz Moura, Luma, additional, de Souza, Ariane Faria, additional, Denani, Caio Bidueira, additional, da Silva, Stephanie Almeida, additional, Pimentel, Thiago Goes, additional, de Oliveira Silva Ferreira, Victor, additional, Azamor, Tamiris, additional, Ano Bom, Ana Paula Dinis, additional, da Penha Gomes Gouvea, Maria, additional, Mill, José Geraldo, additional, Valim, Valéria, additional, Polese, Jessica, additional, Campi-Azevedo, Ana Carolina, additional, Peruhype-Magalhães, Vanessa, additional, Teixeira-Carvalho, Andréa, additional, Martins-Filho, Olindo Assis, additional, de Lima, Sheila Maria Barbosa, additional, and de Sousa Junior, Ivanildo Pedro, additional

Published
2024
Full Text
View/download PDF

9. Serum biomarker profile orchestrating the seroconversion status of patients with autoimmune diseases upon planned primary 17DD Yellow fever vaccination

Author

da Costa-Rocha, Ismael Artur, Machado, Ketty Lysie Libardi Lira, Campi-Azevedo, Ana Carolina, Teixeira-Carvalho, Andréa, Peruhype-Magalhães, Vanessa, de Lima, Sheila Maria Barbosa, Miranda, Emily Hime, Trindade, Gisela Freitas, Casagrande, Thays Zanon, Miyamoto, Samira Tatiyama, Deotti, Sávio Carvalho, Barbosa, Rafaela Villa Real, Rocha, Priscila Costa Martins, Serrano, Erica Vieira, Dinis, Valquiria Garcia, Gouvêa, Sônia Alves, Gavi, Maria Bernadete Renoldi de Oliveira, da Silva, Lidia Balarini, Duque, Ruben Horst, Gianordoli, Ana Paula Espíndula, Bissoli, Maria de Fatima, Gouvea, Maria da Penha Gomes, Pinto-Neto, Lauro Ferreira da Silva, Burian, Ana Paula Neves, Fantinato, Francieli Fontana Sutile Tardetti, Pileggi, Gecilmara Salviato, da Mota, Licia Maria Henrique, Valim, Valéria, and Martins-Filho, Olindo Assis

Published
2021
Full Text
View/download PDF

10. The effect of antimalarials on the safety and persistence of treatment with biologic agents or Janus kinase inhibitors in rheumatoid arthritis.

Author

Bredemeier, Markus, Duarte, Ângela L, Pinheiro, Marcelo M, Kahlow, Bárbara S, Macieira, José C, Ranza, Roberto, Miranda, José R, Valim, Valéria, Castro, Gláucio R de, Bértolo, Manoel B, Sauma, Maria F, Fernandes, Vander, Ribeiro, Ana C, Teodoro, Reginaldo B, Brenol, Claiton V, Carvalho, Hellen M, Studart, Sâmia A, Pinheiro, Geraldo R, Rocha, Laurindo F da, and Lima, Hugo D de

Subjects
BIOTHERAPY, COMBINATION drug therapy, CONFIDENCE intervals, BIOLOGICAL products, TREATMENT duration, REGRESSION analysis, JANUS kinases, ANTIRHEUMATIC agents, HEPATOTOXICOLOGY, RHEUMATOID arthritis, DESCRIPTIVE statistics, SURVIVAL analysis (Biometry), RESEARCH funding, NEUROTRANSMITTER uptake inhibitors, ANTIMALARIALS, DRUG side effects, PATIENT safety, PROPORTIONAL hazards models
Abstract

Objectives To test the association of use of antimalarials with the overall safety of treatment in RA patients receiving one or multiple courses of biologic (b)DMARDs or a Janus kinase inhibitor (JAKi). Methods BiobadaBrasil is a multicentric registry-based cohort study of Brazilian patients with rheumatic diseases starting their first bDMARD or JAKi. The present analysis includes RA patients recruited from January 2009 to October 2019, followed up over one or multiple (up to six) courses of treatment (latest date, 19 November 2019). The primary outcome was the incidence of serious adverse events (SAEs). Total and system-specific adverse events (AEs) and treatment interruption served as secondary outcomes. Negative binomial regression with generalized estimating equations (to estimate multivariate incidence rate ratios, mIRR) and frailty Cox proportional hazards models were used for statistical analyses. Results The number of patients enrolled was 1316 (2335 treatment courses, 6711 patient-years [PY]; 1254.5 PY on antimalarials). The overall incidence of SAEs was 9.2/100 PY. Antimalarials were associated with reduced risk of SAEs (mIRR: 0.49; 95% CI: 0.36, 0.68; P  < 0.001), total AEs (0.68; 95% CI: 0.56, 0.81; P  < 0.001), serious infections (0.53; 95% CI: 0.34, 0.84; P  = 0.007) and total hepatic AEs (0.21; 95% CI: 0.05, 0.85; P  = 0.028). Antimalarials were also related to better survival of treatment course (P  = 0.003). There was no significant increase in the risk of cardiovascular AEs. Conclusion Among RA patients on treatment with bDMARDs or JAKi, concomitant use of antimalarials was associated with reduced the incidence of serious and total AEs and with longer treatment course survival. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

11. EVENTOS ADVERSOS À 3ª DOSE DAS VACINAS ASTRAZENECA E PFIZER EM UMA COORTE DE TRABALHADORES DA SAÚDE

Author

Gouvea, Maria da Penha Gomes, primary, Moulaz, Isac Ribeiro, additional, Gouveia, Thayná Martins, additional, Thompson, Beatriz Paoli, additional, Lança, Karen Evelin Monlevade, additional, Lacerda, Bárbara Sthefany de Paula, additional, Lacerda, Gabriela Curto Cristianes, additional, Lenzi, João Pedro Gonçalvez, additional, Miossi, João Pedro Moraes, additional, Rassele, Matheus Leite, additional, Pimentel, Felipe de Castro, additional, Ramos, Sabrina de Souza, additional, and Valim, Valéria, additional

Published
2023
Full Text
View/download PDF

12. Panoramic snapshot of serum soluble mediator interplay in pregnant women with convalescent COVID-19: an exploratory study

Author

Fernandes, Geraldo Magela, primary, Sasaki, Lizandra Moura Paravidine, additional, Jardim-Santos, Gabriela Profírio, additional, Schulte, Heidi Luise, additional, Motta, Felipe, additional, da Silva, Ângelo Pereira, additional, de Carvalho, Aleida Oliveira, additional, Pereira, Yacara Ribeiro, additional, Alves, Caroline de Oliveira, additional, de Araújo Júnior, David Alves, additional, Mendonça-Silva, Dayde Lane, additional, Costa, Karina Nascimento, additional, de Castro, Maria Eduarda Canellas, additional, Lauand, Lucas, additional, Nery, Rodrigo de Resende, additional, Tristão, Rosana, additional, Kurizky, Patricia Shu, additional, Nóbrega, Otávio de Toledo, additional, Espindola, Laila Salmen, additional, de Castro, Luiz Cláudio Gonçalves, additional, Alpoim, Patrícia Nessralla, additional, Godoi, Lara Carvalho, additional, Dusse, Luci Maria Sant Ana, additional, Coelho-dos-Reis, Jordana Grazziela Alves, additional, Amaral, Laurence Rodrigues do, additional, Gomes, Matheus de Souza, additional, Bertarini, Pedro Luiz Lima, additional, Brito-de-Sousa, Joaquim Pedro, additional, Costa-Rocha, Ismael Artur da, additional, Campi-Azevedo, Ana Carolina, additional, Peruhype-Magalhães, Vanessa, additional, Teixeira-Carvalho, Andrea, additional, Zaconeta, Alberto Moreno, additional, Soares, Alexandre Anderson de Sousa Munhoz, additional, Valim, Valéria, additional, Gomes, Ciro Martins, additional, de Albuquerque, Cleandro Pires, additional, Martins-Filho, Olindo Assis, additional, and da Mota, Licia Maria Henrique, additional

Published
2023
Full Text
View/download PDF

13. Clinical risk factors for predicting anti-Sars-CoV-2 antibody immunoreactivity duration after mild COVID-19 infection

Author

Da Penha Gomes Gouvea, Maria, primary, Gonçalves Henriques, Allan, additional, Eduarda Morais Hibner Amaral, Maria, additional, Ribeiro Moulaz, Isac, additional, Polese, Jéssica, additional, Evelin Monlevade Lança, Karen, additional, Martins Gouveia, Thayná, additional, Sthefany de Paula Lacerda, Bárbara, additional, Paoli Thompson, Beatriz, additional, Geraldo Mill, José, additional, and Valim, Valéria, additional

Published
2023
Full Text
View/download PDF

14. CARDIOVASCULAR RISK IN SJÖGREN S DISEASE FROM THE BRAZILIAN SJÖGREN S DISEASE REGISTRY (REBRAS)

Author

Serrano, Érica Vieira, primary, Reis, Pâmela Peres dos, additional, Ferreira, Beatriz Nicoli, additional, Nóia, João Pedro de Castro Carvalho, additional, Marques, Regis Suwa, additional, Pugliesi, Alisson, additional, Appenzeller, Simone, additional, Ribeiro, Sandra Lúcia Euzébio, additional, Cantali, Diego Ustárroz, additional, Carneiro, Bárbara Seabra, additional, Melo, Natália Seixas de, additional, Oliveira, Fabíola Reis de, additional, Marzola, Mateus Maia, additional, Motta, Ana Carolina Fragoso, additional, Pinheiro, Aysa César, additional, Santos, Paula Regina Toche dos, additional, Lopes, Maria Lúcia Lemos, additional, Coradin, Rafael, additional, Tanure, Leandro Augusto, additional, Xavier, Clarice Garcia Valadares, additional, Trevisani, Virginia Fernandes Moça, additional, Machado, Adriana, additional, Santos, Laura Caldas dos, additional, Miyamoto, Samira Tatiyama, additional, and Valim, Valéria, additional

Published
2023
Full Text
View/download PDF

17. POSITIVITY OF ANTI-LA/SSB ANTIBODIES IN SJÖGREN S DISEASE IS ASSOCIATED WITH EXTRA-GLANDULAR SYSTEMIC MANIFESTATION: RESULTS FROM THE THE BRAZILIAN SJÖGREN S DISEASE REGISTRY (REBRAS)

Author

Cantali, Diego Ustárroz, primary, Ribeiro, Sandra Lúcia Euzébio, additional, Carneiro, Bárbara Seabra, additional, Melo, Natália Seixas de, additional, Marques, Regis Suwa, additional, Pugliesi, Alisson, additional, Appenzeller, Simone, additional, Oliveira, Fabíola Reis de, additional, Marzola, Mateus Maia, additional, Motta, Ana Carolina Fragoso, additional, Trevisani, Virginia Fernandes Moça, additional, Machado, Adriana, additional, Santos, Laura Caldas dos, additional, Lopes, Maria Lúcia Lemos, additional, Coradin, Rafael, additional, Pinheiro, Aysa César, additional, Santos, Paula Regina Toche dos, additional, Tanure, Leandro Augusto, additional, Xavier, Clarice Garcia Valadares, additional, Hax, Vanessa, additional, Capobianco, Karina Gatz, additional, Santos, Tiane Crestani dos, additional, Goularte, Leonardo Santiago, additional, Reis, Pâmela Peres dos, additional, Ferreira, Beatriz Nicoli, additional, Serrano, Erica Vieira, additional, Nóia, João Pedro de Castro Carvalho, additional, Miyamoto, Samira Tatiyama, additional, and Valim, Valéria, additional

Published
2023
Full Text
View/download PDF

18. THE EFFECT OF ANTIMALARIALS ON THE RISK AND SEVERITY OF BACTERIAL, VIRAL, FUNGAL AND SYSTEMIC SPECIFIC INFECTIONS IN RHEUMATOID ARTHRITIS

Author

Bredemeier, Markus, primary, Campos, Monica, additional, Della, Felipe, additional, Duarte, Angela, additional, Pinheiro, Marcelo, additional, Stadler, Barbara, additional, Macieira, Jose Caetano, additional, Ranza, Roberto, additional, Miranda, Jose, additional, Valim, Valéria, additional, Castro, Glaucio, additional, Bertolo, Manoel, additional, Sauma, Maria de Fátima, additional, Fernandes, Vander, additional, Medeiros-Ribeiro, Ana Cristina, additional, Botelho, Reginaldo, additional, Brenol, Claiton, additional, Carvalho, Hellen Mary da Silveira de, additional, Studart, Samia, additional, Pinheiro, Geraldo da Rocha Castelar, additional, Rocha Junior, Laurindo, additional, Lima, Hugo de Leon de, additional, Pereira, Ivanio, additional, Gazzeta, Morgana Ohira, additional, Kakehasi, Adriana, additional, Louzada Junior, Paulo, additional, Hayata, Andre Luiz Shinji, additional, Lupo, Cristiano, additional, Silveira, Ines Guimaraes, additional, Kowalski, Sergio, additional, Titton, David, additional, Ranzolin, Aline, additional, Xavier, Ricardo, additional, Laurindo, Ieda, additional, and Loures, Marco Antonio Araujo da Rocha, additional

Published
2023
Full Text
View/download PDF

20. EFFECTS OF MANUAL VAGUS NERVE THERAPY COMBINED WITH TRANSCRANIAL DIRECT CURRENT STIMULATION ON PAIN IN WOMEN WITH FIBROMYALGIA: A RANDOMIZED CONTROLLED TRIAL

Author

Torres, Aebe Alves, primary, Cordeiro, Bárbara Naeme Lima, additional, Miyamoto, Samira Tatiyama, additional, Pestana, Andressa Braz Carlini, additional, Valim, Valéria, additional, Gomes, Gustavo Pinto de Oliveira, additional, Vidal, Pâmela Reis, additional, Kuster, Elizangela, additional, Bonfim, Izabela Moreira, additional, and Arêas, Fernando Zanela da Silva, additional

Published
2023
Full Text
View/download PDF

22. Unbalanced networks and disturbed kinetics of serum soluble mediators associated with distinct disease outcomes in severe COVID-19 patients

Author

Jardim-Santos, Gabriela Profírio, primary, Schulte, Heidi Luise, additional, Kurizky, Patricia Shu, additional, Gomes, Ciro Martins, additional, Nóbrega, Otávio Tolêdo, additional, de Gois, Eliana Teles, additional, de Carvalho, Maíra Rocha Machado, additional, Martins, Francielle Pulccinelli, additional, Nicola, André Moraes, additional, de Albuquerque, Cleandro Pires, additional, Espindola, Laila Salmen, additional, Naves, Luciana Ansaneli, additional, Soares, Alexandre Anderson de Sousa Munhoz, additional, Albuquerque, Patrícia, additional, Fontes, Wagner, additional, Amaral, Laurence Rodrigues do, additional, Gomes, Matheus de Souza, additional, Bertarini, Pedro Luiz Lima, additional, Brito-de-Sousa, Joaquim Pedro, additional, Campi-Azevedo, Ana Carolina, additional, Peruhype-Magalhães, Vanessa, additional, Teixeira-Carvalho, Andrea, additional, Valim, Valéria, additional, Martins-Filho, Olindo Assis, additional, and da Mota, Licia Maria Henrique, additional

Published
2022
Full Text
View/download PDF

23. Comparison Of The Immunogenicity Among Covid-19 Vaccines Chadox1, Coronavac Or Bnt162b2 In Systemic Lupus Erythematosus (Sle): A Prospective Cohort

Author

Ribeiro, Priscila Dias Cardoso, primary, Peixoto, Flávia Maria Matos Melo Campos, additional, Reis Neto, Edgard Torres dos, additional, Pileggi, Gecilmara Salviato, additional, Bellei, Nancy Cristina Junqueira, additional, Valim, Valéria, additional, Carvalho, Andrea Teixeira de, additional, Souza, Viviane Angelina de, additional, Ferreira, Gilda Aparecida, additional, Pinheiro, Marcelo de Medeiros, additional, Monticielo, Odirlei Andre, additional, Xavier, Ricardo Machado, additional, and Sato, Emília Inoue, additional

Published
2022
Full Text
View/download PDF

24. ARTICULAR SYSTEMIC DISEASE ACTIVITY AT DIAGNOSIS IS ASSOCIATED WITH DAMAGE, FATIGUE, PAIN AND DRYNESS OVER TIME IN PRIMARY SJÖGREN’S SYNDROME

Author

Valim, Valéria, primary, Miyamoto, Samira Tatiyama, additional, Serrano, Erica Vieira, additional, Machado, Ketty Lysie Libardi Lira, additional, Gianordoli, Ana Paula Espindul, additional, Aguiar, Laura Gonçalves Rodrigues, additional, Reis, Pâmela Peres dos, additional, Nóia, João Pedro de Castro Carvalho, additional, Oliveira, Fabiola Reis de, additional, Rocha, Eduardo Melani, additional, Motta, Ana Carolina Fragoso, additional, Xavier, Clarice Garcia Valadares, additional, Ferreira, Gilda Aparecida, additional, Tanure, Leandro Augusto, additional, Pinheiro, Aysa César, additional, Santos, Paula Regina Toche dos, additional, Capobianco, Karina Gatz, additional, Spohr, Rodrigo Sarmanho, additional, Souto, Laura de Brito, additional, Costa, Poliane Cruz, additional, Medeiros, Clarissa Castro Galvão, additional, Picolo, Maria Lara, additional, Goularte, Leonardo Santiago, additional, Ferrari, Alessandra, additional, Jeffman, Marcelo Wainberg, additional, Costa Filho, Luiz Cesar da, additional, Hax, Vanessa, additional, Ribeiro, Sandra Lúcia Euzébio, additional, Silva, Jessica Carvalho da, additional, Souza, Bruna Lyandra Portela Sena de, additional, Carneiro, Barbara Seabra, additional, Melo, Natália Seixas de, additional, Dias, Marcos Magvinier Sousa, additional, and Silva, Tayana Evelling Uchôa da, additional

Published
2022
Full Text
View/download PDF

25. SAFETY OF THE CORONAVAC AND CHADOX 1 COVID-19 VACCINES IN PATIENTS WITH RHEUMATOID ARTHRITIS: DATA FROM SAFER STUDY

Author

Cruz, Vitor Alves, primary, Silva, Nilzio Antonio da, additional, Nunes, Maisa Brito, additional, Silva, Leonardo Barbosa da, additional, Sartori, Natalia Sarzi, additional, Monticielo, Odirlei Andre, additional, Xavier, Ricardo Machado, additional, Souza, Viviane Angelina de, additional, Rezende, Rodrigo Poubel Vieira de, additional, Ribeiro, Sandra Lucia Elzebio, additional, Melo, Ana Karla Guedes de, additional, Vieira, Rejane Maria R. De Abreu, additional, Machado, Ketty Lysie Libardi Lira, additional, Teixeira-Carvalho, Andréa, additional, Peruhype-Magalhães, Vanessa, additional, Martins-Filho, Olindo Assis, additional, Ferreira, Gilda Aparecida, additional, Pinheiro, Marcelo de Medeiros, additional, Sato, Emilia Inoue, additional, Reis Neto, Edgard Torres dos, additional, Valim, Valéria, additional, Pilleggi, Gecilmara Salviato, additional, Castro, Charlles Heldan de Moura, additional, and Magalhães, Vanessa de Oliveira, additional

Published
2022
Full Text
View/download PDF

26. FATIGUE IS ASSOCIATED WITH SYMPTOMS, DEPRESSION, ANXIETY, SLEEPINESS AND DISEASE ACTIVITY IN PRIMARY SJÖGREN’S SYNDROME

Author

Miyamoto, Samira Tatiyama, primary, Valim, Valéria, additional, Serrano, Erica Vieira, additional, Machado, Ketty Lysie Libardi Lira, additional, Gianordoli, Ana Paula Espindula, additional, Aguiar, Laura Gonçalves Rodrigues, additional, Reis, Pâmela Peres dos, additional, Nóia, João Pedro de Castro Carvalho, additional, Oliveira, Fabiola Reis de, additional, Rocha, Eduardo Melani, additional, Motta, Ana Carolina Fragoso, additional, Pinheiro, Aysa César, additional, Santos, Paula Regina Toche do, additional, Trevisani, Virginia Fernandes Moça, additional, Dardin, Luciana Paula, additional, Ribeiro, Sandra Lúcia Euzébio, additional, Silva, Jessica Carvalho da, additional, Souza, Bruna Lyandra Portela Sena de, additional, Carneiro, Barbara Seabra, additional, Melo, Natália Seixas de, additional, Dias, Marcos Magvinier Sousa, additional, and Silva, Tayana Evelling Uchôa da, additional

Published
2022
Full Text
View/download PDF

27. Safety assessment of BNT162b2, SinoVac and ChAdOx1 vaccines in Systemic Lupus Erythematosus patients – Data from SAFER Study

Author

Peixoto, Flávia Maria Matos Melo Campos, primary, Ribeiro, Priscila Dias Cardoso, additional, Sato, Emilia Inoue, additional, Pileggi, Gecilmara Salviato, additional, Valim, Valéria, additional, Teixeira-Carvalho, Andréa, additional, Souza, Viviane Angelina de, additional, Ferreira, Gilda Aparecida, additional, Pinheiro, Marcelo de Medeiros, additional, Xavier, Ricardo Machado, additional, Monticielo, Odirlei Andre, additional, and Reis Neto, Edgard Torres dos, additional

Published
2022
Full Text
View/download PDF

28. DIFFICULT ACCESS TO PREVENTION AND DETECTION MEASURES OF COVID-19 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Author

Dinis, Valquiria Garcia, primary, Costa, Carolina Zorzanelli, additional, Giovelli, Raquel Altoé, additional, Oliveira, Livia Camara, additional, Valim, Valéria, additional, Gouvea, Maria da Penha Gomes, additional, Reis, Bianca Savazzini, additional, Carneiro, Amanda Vieira de, additional, Mameri, Arnon Salviato, additional, Rasseli, Amanda de Oliveira, additional, Falçoni Júnior, Aldren Thomazini, additional, Severgnine, Diego Goltara, additional, Araujo, Heitor Buback, additional, Silva, Lucas Luciano Rocha, additional, Mendes, Thiago Loureiro, additional, Miossi, Leticia Scopel, additional, Grafanassi, Caio Grafanassi, additional, Barbosa, Rafaella Vila Real, additional, Dias, João Gabriel Fragoso, additional, Mendes, Rafael Gonçalves, additional, Antunes, Enzo Dalfior, additional, Deotti, Sávio Carvalho, additional, Surlo, Heitor Filipe, additional, Pereira, Thallys Henrique Alves, additional, Alves, Rachel Sant’Ana, additional, Garcia, Gabriel Magevski, additional, Santos, Fernanda Dornelas Nogueira dos, additional, and Garrute, Paulo Henrique Galvêas, additional

Published
2022
Full Text
View/download PDF

29. VALIDITY AND RELIABILITY OF THE BRAZILIAN VERSION OF THE PRIMARY SJÖGREN’S SYNDROME QUESTIONNAIRE

Author

Miyamoto, Samira Tatiyama, primary, Noronha, Bianca Domingos, additional, Santos, Pedro Henrique Alves dos, additional, Serrano, Erica Vieira, additional, Gianordoli, na Paula Espindula, additional, Altoe, Lara Betini, additional, Silva, Nicole Reis Souza da, additional, Pedrini, Ana Paula Truhlar, additional, Valim, Valéria, additional, Favarato, Letícia Fonseca, additional, Alochio, Luíza Vallory, additional, and Tomé, Weider Andrade, additional

Published
2022
Full Text
View/download PDF

30. IMMUNOGENICITY AND SAFETY OF THE CHADOX-1 COVID-19 VACCINE IN PATIENTS WITH AUTOIMMUNE DISEASES AND HEALTHY CONTROLS: DATA FROM SAFER STUDY

Author

Machado, Ketty Lysie Libardi Lira, primary, Miyamoto, Samira Tatiyama, additional, Moulin, Anna Carolina Simões, additional, Dias, Laiza Hombre, additional, Burian, Ana Paula Neves, additional, Tuão, Raiza Cansian, additional, Veghini, Débora Marques, additional, Lirio, Maressa Barbosa Beloni, additional, Santo, Thaisa De Moraes Ribeiro Espirito, additional, Batista, Danielle Cristina Filgueira Alves, additional, Souza, Bárbara Oliveira, additional, Macabú, Mariana de Oliveira, additional, Vieira, Gabriel Smith Sobral, additional, Grillo, Luiza Lorenzoni, additional, Lima, Marina Deorce de, additional, Lorencini, Pietra Zava, additional, Athayde, Paula dos Santos, additional, Albertino, Laissa Fiorotti, additional, Corona, Helena da Silva, additional, Aguiar, Laura Gonçalves Rodrigues, additional, Faé, Filipe, additional, Pasti, Laís Pizzol, additional, Surlo, Heitor Filipe, additional, Moulaz, Isac Ribeiro, additional, Oliveira, Yasmin Gurtler Pinheiro de, additional, Pascoal, Vanessa Peruhype Magalhães, additional, Gouveia, Maria da Penha Gomes, additional, Gadelha, Carolina Strauss Estevez, additional, Mill, José Geraldo, additional, Pretti, Flavia Zon, additional, Monticielo, Odirlei Andre, additional, Reis Neto, Edgard Torres dos, additional, Souza, Viviane Angelina de, additional, Pinheiro, Marcelo de Medeiros, additional, Ferreira, Gilda Aparecida, additional, Sato, Emilia Inoue, additional, Xavier, Ricardo Machado, additional, Pileggi, Gecilmara Cristina Salviato, additional, Teixeira-Carvalho, Andréa, additional, Martins Filho, Olindo Assis, additional, and Valim, Valéria, additional

Published
2022
Full Text
View/download PDF

31. Previous biological therapy and impairment of the IFN-γ/IL-10 axis are associated with low immune response to 17DD-YF vaccination in patients with spondyloarthritis

Author

Casagrande, Thays Zanon, primary, Costa-Rocha, Ismael Artur da, additional, Gavi, Maria Bernadete Renoldi de Oliveira, additional, Miyamoto, Samira Tatiyama, additional, Martins, Priscila Costa, additional, Serrano, Érica Vieira, additional, Dinis, Valquiria Garcia, additional, Machado, Ketty Lysie Libardi Lira, additional, Gouvea, Sonia Alves, additional, Caser, Larissa Carvalho, additional, Campi-Azevedo, Ana Carolina, additional, Teixeira-Carvalho, Andréa, additional, Peruhype-Magalhães, Vanessa, additional, Bissoli, Maria de Fatima, additional, Gouvea, Maria da Penha Gomes, additional, Lima, Sheila Maria Barbosa de, additional, Miranda, Emily Hime, additional, Trindade, Gisela Freitas, additional, Lyra, Danielle Grillo Pacheco, additional, Burian, Ana Paula Neves, additional, Neto, Lauro Ferreira da Silva Pinto, additional, da Mota, Licia Maria Henrique, additional, Martins-Filho, Olindo Assis, additional, and Valim, Valéria, additional

Published
2022
Full Text
View/download PDF

32. REATOGENICIDADE COM MEIA DOSE DA VACINA CHADOX1 NCOV-19 (AZD1222)

Author

Gouvea, Maria da Penha Gomes, Filho, Olindo Assis Martins, Carvalho, Andrea Teixeira, Camacho, Luiz Antônio Bastos, Villela, Daniel A. Maciel, Neto, Lauro Ferreira Pinto, Domingues, Carla, Moulaz, Isac Ribeiro, Gouveia, Thayná Martins, Thompson, Beatriz Paoli, Lança, Karen Evelin Monlevade, Lacerda, Gabriela Curto Cristianes, Lenzi, João Pedro Gonçalves, Ramos, Sabrina de Souza, Miossi, João Pedro Moraes, Rassele, Matheus Leite, Pimentel, Felipe de Castro, Roza, Thais Luma de Oliveira, Ramos, Alessandro Demoner, Henriques, Allan Gonçalves, Amaral, Maria Eduarda Moraes Hibner, Surlo, Heitor Filipe, Vieira, Gabriel Smith Sobral, Pasti, Laís Pizzol, Grillo, Luiza Lorenzoni, Aguiar, Laura Gonçalves Rodrigues, Rosi, Matheus Pereira, Rizzi, Ramon Borge, Athayde, Paula dos Santos, Lorencini, Pietra Zava, Silva, Adriana Santos, Reuter, Tania, Jubini, Jaquelini, Lyra, Danielle Grillo Pacheco, Rodrigues, Rodrigo Ribeiro, da Silva, Cristiano Soares, Reblin, Luís Carlos, Cardoso, Orlei, Miyamoto, Samira T., Machado, Ketty Lysie Libardi Lira, Forechi, Ludimila, Strauss, Carolina, Percio, Jadher, Barrera, Lely Stella Guzmán, Junior, Nésio Fernandes de Medeiros, Lallemand, Karina Rosemarie, Neto, Manoel Rodrigues Lima, Mill, José Geraldo, and Valim, Valéria

Published
2022
Full Text
View/download PDF

33. EVENTOS ADVERSOS ÀS VACINAS CORONAVAC E ASTRAZENECA EM UMA COORTE DE TRABALHADORES DA SAÚDE

Author

Gouvea, Maria da Penha Gomes, Rocha, Waltésia Perini, Moulaz, Isac Ribeiro, Miossi, Rúbia, Gouveia, Thayná Martins, Thompson, Beatriz Paoli, Lança, Karen Evelin Monlevade, Lacerda, Barbara Sthefany de Paula, Lacerda, Gabriela Curto Cristianes, Lenzi, João Pedro Gonçalves, Miossi, João Pedro Moraes, Rassele, Matheus Leite, Pimentel, Felipe de Castro, Ramos, Sabrina de Souza, Forechi, Ludimila, Faé, Filipe, Moulin, Anna Carolina Simões, de Barros, Arthur Prando, Souza, Bárbara Oliveira, Surlo, Heitor Filipe, Vieira, Gabriel Smith Sobral, de Lima, Marina Deorce, Pasti, Laís Pizzol, Grillo, Luiza Lorenzoni, Aguiar, Laura Gonçalves Rodrigues, Athayde, Paula, Lorencini, Pietra Zava, Ribeiro, Hellen Carvalho, Soares, Cinthia Eduarda Santos, Macabú, Mariana, Henriques, Allan Gonçalves, Amaral, Maria Eduarda Moraes Hibner, Fiorot, Laíssa, Machado, Ketty Lysie Libardi Lira, Mill, José Geraldo, and Valim, Valéria

Published
2022
Full Text
View/download PDF

34. REATIVIDADE VACINAL E DURAÇÃO DE RESPOSTA IMUNE DA CORONAVAC E ASTRAZENECA EM UMA COORTE DE TRABALHADORES

Author

Gouvea, Maria da Penha Gomes, Moula, Isac Ribeiro, Gouveia, Thayná Martins, Thompson, Beatriz Paoli, Lança, Karen Evelin Monlevade, Lacerda, Gabriela Curto Cristianes, Lenzi, João Pedro Gonçalves, Ramos, Sabrina de Souza, Lacerda, Barbara Sthefany de Paula, Forechi, Ludimila, Filho, Olindo Assis Martins, de Carvalho, Andréa Teixeira, Camacho, Luiz Antonio Bastos, Villela, Daniel Antunes Maciel, Pinto Neto, Lauro, Faé, Filipe, Moulin, Anna Carolina Simões, de Barros, Arthur Prando, Souza, Bárbara Oliveira, Surlo, Heitor Filipe, Vieira, Gabriel Smith Sobral, de Lima, Marina Deorce, Pasti, Laís Pizzol, Grillo, Luiza Lorenzoni, Aguiar, Laura Gonçalves Rodrigues, Athayde, Paula, Lorencini, Pietra Zava, Ribeiro, Hellen Carvalho, Soares, Cinthia Eduarda Santos, Macabú, Mariana, Albertino, Laíssa Fiorotti, Miossi, João Pedro Moraes, Rassele, Matheus Leite, Pimentel, Felipe de Castro, Henriques, Allan Gonçalves, Amaral, Maria Eduarda Moraes Hibner, Machado, Ketty Lysie Libardi Lira, Mill, José Geraldo, and Valim, Valéria

Published
2022
Full Text
View/download PDF

35. EFETIVIDADE, IMUNOGENICIDADE E SEGURANÇA DA MEIA DOSE DA VACINA CHADOX1 NCOV-19 CONTRA SARS-COV2 (PROJETO VIANA)

Author

Valim, Valéria, Gouvea, Maria da Penha Gomes, Filho, Olindo Assis Martins, Carvalho, Andrea Teixeira, Camacho, Luiz Antônio Bastos, Villela, Daniel A. Maciel, Neto, Lauro Ferreira Pinto, Domingues, Carla, Moulaz, Isac Ribeiro, Thompson, Beatriz Paoli, Lança, Karen Evelin Monlevade, Lacerda, Gabriela Curto Cristianes, Lenzi, João Pedro Gonçalvez, Ramos, Sabrina de Souza, Miossi, João Pedro Moraes, Rassele, Matheus Leite, Pimentel, Felipe de Castro, Henriques, Allan Gonçalves, Amaral, Maria Eduarda Moraes Hibner, Silva, Lucas Santos, Pasti, Laís, Vieira, Gabriel Smith Sobral, Roza, Thais Luma de Oliveira, Ramos, Alessandro Demoner, Surlo, Heitor Filipe, Grillo, Luiza Lorenzoni, Aguiar, Laura Gonçalves Rodrigues, Rosi, Matheus Pereira, Rizzi, Ramon Borge, Athayde, Paula dos Santos, Lorencini, Pietra Zava, Silva, Adriana Santos, Reuter, Tania, Jubini, Jaquelini, Lyra, Danielle Grillo Pacheco, Rodrigues, Rodrigo Ribeiro, da Silva, Cristiano Soares, Reblin, Luís Carlos, Cardoso, Orlei, Miyamoto, Samira T., Machado, Ketty Lysie Libardi Lira, Forechi, Ludimila, Strauss, Carolina, Percio, Jadher, Barrera, Lely Stella Guzmán, Junior, Nésio Fernandes de Medeiros, and Mill, José Geraldo

Published
2022
Full Text
View/download PDF

37. Safety of the Methotrexate–leflunomide Combination in Rheumatoid Arthritis: Results of a Multicentric, Registry-based, Cohort Study (BiobadaBrasil)

Author

Bredemeier, Markus, primary, Ranza, Roberto, additional, Kakehasi, Adriana M., additional, Ranzolin, Aline, additional, da Silveira, Inês G., additional, Ribeiro, Ana C.M., additional, Titton, David C., additional, Hayata, André L.S., additional, Carvalho, Hellen M.S., additional, Kahlow, Bárbara S., additional, Fernandes, Vander, additional, Louzada, Paulo, additional, Bértolo, Manoel B., additional, Duarte, Ângela L.B.P., additional, Macieira, José C., additional, Miranda, José R.S., additional, Pinheiro, Geraldo R.C., additional, Teodoro, Reginaldo B., additional, Pinheiro, Marcelo M., additional, Valim, Valéria, additional, Pereira, Ivânio A., additional, Sauma, Maria F.L.C., additional, de Castro, Gláucio R.W., additional, da Rocha, Laurindo F., additional, Studart, Sâmia A.S., additional, Gazzeta, Morgana O., additional, da Silveira, Leticia G., additional, Lupo, Cristiano M., additional, and Laurindo, Ieda M.M., additional

Published
2022
Full Text
View/download PDF

38. Anti-SARS-CoV-2 antibody immunoreactivity profiles during COVID-19 recurrence

Author

Gouvea, Maria da Penha Gomes, primary, Moulaz, Isac Ribeiro, additional, Gouveia, Thayná Martins, additional, Lança, Karen Evelin Monlevade, additional, Lacerda, Bárbara Sthefany de Paula, additional, Thompson, Beatriz Paoli, additional, Polese, Jéssica, additional, Lima, Marina Deorce de, additional, Ribeiro-Rodrigues, Rodrigo, additional, Mill, José Geraldo, additional, and Valim, Valéria, additional

Published
2022
Full Text
View/download PDF

39. Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium

Author

Retamozo, Soledad, primary, Acar-Denizli, Nihan, additional, Horváth, Ildiko Fanny, additional, Ng, Wan-Fai, additional, Rasmussen, Astrid, additional, Dong, Xu, additional, Li, Xiaomei, additional, Baldini, Chiara, additional, Olsson, Peter, additional, Priori, Roberta, additional, Seror, Raphaèle, additional, Gottenberg, Jacques-Eric, additional, Kruize, Aike A., additional, Hernandez-Molina, Gabriela, additional, Vissink, Arjan, additional, Sandhya, Pulukool, additional, Armagan, Berkan, additional, Quartuccio, Luca, additional, Sebastian, Agata, additional, Praprotnik, Sonja, additional, Bartoloni, Elena, additional, Kwok, Seung-Ki, additional, Kvarnstrom, Marika, additional, Rischmueller, Maureen, additional, Soláns-Laqué, Roser, additional, Sene, Damien, additional, Pasoto, Sandra G., additional, Suzuki, Yasunori, additional, Isenberg, David A., additional, Valim, Valéria, additional, Nordmark, Gunnel, additional, Nakamura, Hideki, additional, Fernandes Moça Trevisani, Virginia, additional, Hofauer, Benedikt, additional, Sisó-Almirall, Antoni, additional, Giacomelli, Roberto, additional, Devauchelle-Pensec, Valerie, additional, Bombardieri, Michele, additional, Atzeni, Fabiola, additional, Hammenfors, Daniel, additional, Maure, Brenda, additional, Carsons, Steven E., additional, Gheita, Tamer, additional, Sánchez-Berná, Isabel, additional, López-Dupla, Miguel, additional, Morel, Jacques, additional, Inanç, Nevsun, additional, Fonseca-Aizpuru, Eva, additional, Morcillo, César, additional, Vollenweider, Cristina, additional, Melchor, Sheila, additional, Vázquez, Marcos, additional, Díaz-Cuiza, Ericka, additional, Consani-Fernández, Sandra, additional, de-Miguel-Campo, Borja, additional, Szántó, Antónia, additional, Bombardieri, Stefano, additional, Gattamelata, Angelica, additional, Hinrichs, Anneline, additional, Sánchez-Guerrero, Jorge, additional, Danda, Debashish, additional, Kilic, Levent, additional, De Vita, Salvatore, additional, Wiland, Piotr, additional, Gerli, Roberto, additional, Park, Sung-Hwan, additional, Wahren-Herlenius, Marie, additional, Bootsma, Hendrika, additional, Mariette, Xavier, additional, Ramos-Casals, Manuel, additional, and Brito-Zerón, Pilar, additional

Published
2021
Full Text
View/download PDF

40. Clinical risk factors for predicting anti-Sars-Cov-2 antibody immunoreactivity duration after mild COVID-19 infection.

Author

Gomes Gouvea, Maria da Penha, Gonçalves Henriques, Allan, Morais Hibner Amaral, Maria Eduarda, Ribeiro Moulaz, Isac, Polese, Jéssica, Monlevade Lança, Karen Evelin, Gouveia, Thayná Martins, de Paula Lacerda, Bárbara Sthefany, Thompson, Beatriz Paoli, Geraldo Mill, José, and Valim, Valéria

Subjects
IMMUNOGLOBULINS, COVID-19, COVID-19 pandemic, HUMORAL immunity, RHINORRHEA, PUBLIC hospitals
Abstract

Copyright of Revista Brasileira de Crescimento e Desenvolvimento Humano is the property of Centro de Estudos de Crescimento e Desenvolvimento do Ser Humano and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
Full Text
View/download PDF

41. Safety of the Methotrexate-leflunomide Combination in Rheumatoid Arthritis: Results of a Multicentric, Registry-based, Cohort Study (BiobadaBrasil).

Author

Bredemeier, Markus, Ranza, Roberto, Kakehasi, Adriana M., Ranzolin, Aline, da Silveira, Inês G., Ribeiro, Ana C. M., Titton, David C., Hayata, André L. S., Carvalho, Hellen M. S., Kahlow, Bárbara S., Fernandes, Vander, Louzada Jr., Paulo, Bértolo, Manoel B., Duarte, Ângela L. B. P., Macieira, José C., Miranda, José R. S., Pinheiro, Geraldo R. C., Teodoro, Reginaldo B., Pinheiro, Marcelo M., and Valim, Valéria

Published
2021
Full Text
View/download PDF

42. Epidemiologic profile of juvenile-onset compared to adult-onset spondyloarthritis in a large Brazilian cohort

Author

Duarte, Angela P., Marques, Cláudia D.L., Bortoluzzo, Adriana B., Gonçalves, Célio R., Silva, José Antonio Braga da, Ximenes, Antonio Carlos, Bértolo, Manoel B., Ribeiro, Sandra Lúcia E., Keiserman, Mauro, Skare, Thelma L., Carneiro, Sueli, Menin, Rita, Azevedo, Valderilio F., Vieira, Walber P., Albuquerque, Elisa N., Bianchi, Washington A., Bonfiglioli, Rubens, Campanholo, Cristiano, Carvalho, Hellen M.S., Costa, Izaias P., Kohem, Charles L., Leite, Nocy, Lima, Sonia A.L., Meirelles, Eduardo S., Pereira, Ivânio A., Pinheiro, Marcelo M., Polito, Elizandra, Resende, Gustavo G., Rocha, Francisco Airton C., Santiago, Mittermayer B., Sauma, Maria de Fátima L.C., Valim, Valéria, and Barros, Percival D. Sampaio

Abstract

To analyze the clinical and epidemiologic characteristics of juvenile-onset spondyloarthritis (SpA) (< 16 years) and compare them with a group of adult-onset (≥ 16 years) SpA patients.

Published
2024
Full Text
View/download PDF

43. Effectiveness, safety, and immunogenicity of half dose ChAdOx1 nCoV-19 COVID-19 Vaccine: Viana project.

Author

Valim V, Martins-Filho OA, Gouvea MDPG, Camacho LAB, Villela DAM, de Lima SMB, Azevedo AS, Neto LFP, Domingues CMAS, de Medeiros Junior NF, Moulaz IR, Dias LH, Miyamoto ST, Teixeira-Carvalho A, and Mill JG

Subjects
Antibodies, Neutralizing, Antibodies, Viral, Humans, COVID-19 prevention & control, COVID-19 Vaccines adverse effects, ChAdOx1 nCoV-19
Abstract

Fractional dose is an important strategy to increase access to vaccines. This study evaluated the effectiveness, safety, and immunogenicity of half dose of ChAdOx1 nCoV-19 vaccine. A non-inferiority non-randomized controlled trial compared a half dose of ChAdOx1 nCoV-19 with the full dose, with an interval of 8 to 10 weeks, in individuals aged 18-49 years. The primary endpoints were the incidence rate of new cases/1,000 person-year at 90 days after 14 days of the second dose, confirmed by RT-PCR and new cases registered at SUS National Health Surveillance Database (e-SUS VS). The anti-SARS-CoV-2 spike (S) protein receptor binding domain (RBD) by chemiluminescence and the neutralizing antibodies by plaque reduction neutralization test (PRNT) were titrated. The soluble biomarkers were quantified with a multiplex immunoassay. Follow-up was 90 days after 14 days of the second dose. A total of 29,598 individuals were vaccinated. After exclusion, 16,570 individuals who received half a dose and 6,402 who received full doses were analyzed. The incidence of new cases confirmed by RT-PCR of half dose was non-inferior to full dose (23.7 vs. 25.7 cases per 1,000 persons-year [coefficient group -0.09 CI95%(-0.49 to 0.31)], even after adjusting for age and sex. There were no deaths or hospitalization after immunization of either group. Immunogenicity was evaluated in a subsample (N=558) compared to 154 healthcare workers who received a full dose. The seroconversion rate in seronegative individuals at baseline half dose was 99.8%, similar to that of the full dose (100%). Geometric mean concentration (95% CI; BAU/mL) were half dose = 188 (163-217) and full dose = 529 (423-663) (p < 0.001). In seropositive subjects at baseline (pre-immune individuals), the first dose induced very high and similar IgG-S in half dose 1,359 (1,245-1,483) and full dose 1,354 (1,048-1,749) BAU/mL. A half dose induced a high increase in plasma chemokines, pro-inflammatory/regulatory cytokines, and growth factors. The frequency of adverse events was similar. No serious adverse events or deaths were reported. A half dose of ChAdOx1 nCoV-19 is as effective, safe, and immunogenic as the full dose. The immune response in pre-immune (seropositive in the baseline) individuals indicates that the half dose may be a booster dose schedule., Competing Interests: Authors OM-F, LC, DV, SL, AA, and AT-C are staff members of FIOCRUZ, responsible for manufacturing the ChAdOx1 nCoV-19 COVID-19 vaccine. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Valim, Martins-Filho, Gouvea, Camacho, Villela, de Lima, Azevedo, Neto, Domingues, de Medeiros Junior, Moulaz, Dias, Miyamoto, Teixeira-Carvalho, Mill and Half Dose ChAdOx Study Group.)

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results