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Aim: The aim of this study was to investigate the pregnancy outcome of patients taking beta-blockers for the treatment of maternal cardiac arrhythmias. Materials and Method: This study was a retrospective observational study involving 50 pregnant women with cardiac arrhythmias and 55 healthy pregnant women, admitted between January 1, 2020 and January 1, 2022, to Ankara City Hospital. Beta-blockers were classified into three groups: metaprolol, propranolol, and bisoprolol. The use of beta-blockers was examined in two groups: high-dose and low-dose. For pregnancy outcome, birth week, birth weight and birth weight Z-score, beta human chorionic gonadotrophin (bHCG) MoM and pregnancy-associated plasma protein A (PAPP-A) MoM, neonatal APGAR score, and neonatal intensive care unit admission (NICU) rates were determined. Results: The patient group taking beta-blockers had a statistically significant earlier delivery week than the group without beta-blocker use (p= <0.001). The rate of primary cesarean deliveries was higher in the study group (p= 0.007). Birth weight and APGAR score at the fifth minute was significantly lower in the study group, and NICU admission rate was significantly higher (p= 0.006, p= <0.001and p= <0.001, respectively). Conclusion: Beta-blockers, a first-line therapy for maternal arrhythmias, may affect fetal development and pregnancy outcomes. İt is recommended that these drugs to be administered are meticulously selected for appropriate subgroups, with lowest effective doses. [ABSTRACT FROM AUTHOR]

Purpose: This study aims to investigate the fetal Evans Index and establish a nomogram for fetuses without any additional fetal anomalies detected during the prenatal period., Methods: We conducted our research at Ankara City Hospital, including 894 patients who were admitted and evaluated between gestational weeks 16-40. These patients had no fetal anomalies detected in subsequent gestational weeks. Descriptive data, such as age, gravidity, parity, and body mass index (BMI), were recorded. Gestational week and Evans Index (mean, median, standard deviation, minimum, maximum, and percentile) were also documented. The Evans index was calculated as the ratio between the maximal width of the frontal horns and the maximal width of the inner diameter of the cranium., Results: We evaluated 894 fetuses in pregnant women had no fetal anomalies detected throughout the pregnancy. The evaluation took place at different gestational weeks, and a nomogram for the Evans Index was created., Conclusions: It is relevant for clinicians and researchers to be aware of the range of fetal Evans Index values across different gestational weeks as a prognostic criterion., (© 2024 Wiley Periodicals LLC.)