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Emerging viruses threaten global health, but few experimental models can characterize the virus and host factors necessary for within- and cross-species transmission. Here, we leverage a model whereby pet store mice or rats-which harbor natural rodent pathogens-are cohoused with laboratory mice. This "dirty" mouse model offers a platform for studying acute transmission of viruses between and within hosts via natural mechanisms. We identified numerous viruses and other microbial species that transmit to cohoused mice, including prospective new members of the Coronaviridae, Astroviridae, Picornaviridae, and Narnaviridae families, and uncovered pathogen interactions that promote or prevent virus transmission. We also evaluated transmission dynamics of murine astroviruses during transmission and spread within a new host. Finally, by cohousing our laboratory mice with the bedding of pet store rats, we identified cross-species transmission of a rat astrovirus. Overall, this model system allows for the analysis of transmission of natural rodent viruses and is a platform to further characterize barriers to zoonosis.

This article examines the similarities and differences between the COVID-19 and AIDS pandemics, cautioning against oversimplification and emphasizing the role of social factors in understanding disease. It discusses the concept of "scientific hubris" and how it can overshadow the social aspects of pandemics. The article also explores the idea of societal attitudes shaping neglect and the value placed on certain lives. The authors stress the importance of considering social relations when studying pandemics and their impact on different groups. The report by Andrew Tucker and Gerry Kearns analyzes the impact of globalization on local communities, acknowledging both the economic benefits and cultural losses associated with it. It calls for policymakers to consider the social and cultural consequences of globalization and proposes strategies to mitigate negative effects. Overall, the report provides a balanced perspective on the complex nature of globalization and its implications for local communities. [Extracted from the article]

Documentary filmmakers are gradually embracing immersive media to create novel Virtual Reality Nonfiction (VRNF) content. Over the past twenty years initial experimentation in this new medium has brought forward numerous linearly structured 360° documentaries that maintain a close link to traditional documentary modes. More recently, we have observed a shift from the relatively passive 360° cinema towards more open-world, non-linear, game-like interactive experiences that challenge traditional definitions of the documentary genre. Volumetric world-building techniques provide nonfiction creators with additional tools that afford 'viewer-users' spatial and interactive agency, leading to a heightened autopoietic realisation of the storyworld. VRNF creators have the potential to allow their viewer-users enhanced control over framing, temporal ordering of the plot and spatial unfolding of the diegetic world, thus inviting them to become actual co-creators of a deeply personal and personalized experience. This article addresses how VRNF may go beyond the mere 'documentation' of people, places or past events that existed in a pre-filmic reality and provide viewer-users through augmented agency a unique present-tense autopoietic experience that pushes the boundaries of traditional 2D documentary. [ABSTRACT FROM AUTHOR]

Our understanding of land‐based cool season temperature variability over the past millennium is limited by the relative lack of annually resolved temperature proxies, especially in the Southern Hemisphere. Here, we develop the first earlywood (EW) and latewood (LW) width chronologies from Australia based on the Tasmanian endemic conifer Athrotaxis selaginoides in the far southeast of Australia. We also develop total ring width (RW), EW and LW chronologies from a new site in the far south. We compare the climate responses of RW, EW and adjusted LW chronologies of three A. selagnoides sites near the southern extent of the species with three sites of the species near the northern extent of the species. RW and EW at the southern sites are strongly and positively related to cool season temperature (July–October), but in the north, RW and EW are more strongly and positively related with summer (December–February) temperatures. Once adjusted for the influence of the same growing season EW, LW in the north is very strongly negatively correlated with January–February temperatures across southeastern Australia. The new southern RW and EW chronologies can be used to extend one of only two annually resolved regional cool season temperature reconstructions in the Southern Hemisphere back a further 180 years. [ABSTRACT FROM AUTHOR]