Search

Background: There are currently no specific tools available to assess self-efficacy among Vietnamese individuals with colorectal cancer (CRC) post-surgery. Translating and evaluating the psychometric properties of the New General Self-Efficacy Scale (NGSE) for use in the Vietnamese population could help address this gap. Objective: This study aimed to evaluate the psychometric properties of the Vietnamese version of the NGSE scale. Methods: A cross-sectional study was conducted. The sample consisted of 120 individuals aged 20-59 with CRC post-surgery, recruited through a multi-stage sampling technique from three hospitals in Vietnam. The scale was translated into Vietnamese using Brislin’s technique. Content validity was assessed using the Content Validity Index for item (I-CVI) and for scale (S-CVI). Construct validity was examined through confirmatory factor analysis (CFA), and reliability was measured using Cronbach’s α coefficients. Results: The findings showed an I-CVI of 1.00 and an S-CVI of 1.00, indicating excellent content validity. The Cronbach’s α for the NGSE was 0.95, indicating excellent internal consistency. CFA results showed that all eight items fit well within a unidimensional structure (X2 = 48.936, p >0.05, df = 24, X2/df = 2.04, RMSEA = 0.078, CFI = 0.979, TLI = 0.971, SRMR = 0.023). Factor loadings for each item ranged from 0.798 to 0.901. Conclusion: The results suggest that the NGSE scale demonstrates good psychometric properties as applied to the Vietnamese individuals examined in this study. This instrument can be regularly utilized in clinical settings to identify key concerns in colorectal cancer patients’ care and facilitate appropriate nursing interventions to enhance self-efficacy in this population effectively.

Introduction: There is a need for a validated Vietnamese translation of the colorectal cancer subscale (CCS) of the functional assessment of cancer therapy–colorectal (FACT-C) questionnaire to assess colorectal cancer-specific concerns of Vietnamese persons with colorectal cancer post-surgery. Objectives: This study aims to translate and validate the CCS of FACT-C questionnaire in Vietnamese persons with colorectal cancer post-surgery. Methods: The nine-item CCS was translated following the functional assessment of chronic illness therapy (FACIT) translation methodology guidelines. Psychometric properties of a Vietnamese version of the CCS were evaluated with a sample of 135 participants who were randomly selected from three hospitals in Vietnam, utilizing a multistage sampling method. Construct validity was examined through confirmatory factor analysis (CFA), and reliability was assessed using Cronbach's α coefficients. These measures aimed to validate the psychometric properties of the Vietnamese nine-item CCS version. Descriptive statistics were used to analyze participant demographics with SPSS. Results: The translated version demonstrated equivalence to the original English version. CFA results for the CCS Vietnamese version indicated that all 9 items were consistent with a unidimensional questionnaire (χ2 = 69.669, p >.05, df = 27, χ2/df = 2.58, RMSEA =.074, CFI =.917, TLI =.901, SRMR =.057). The Cronbach's α coefficient was.86, indicating high reliability. The Correlated Item-Total Correlation for the 9 items ranged from.39 to.76. Conclusion: The nine-item CCS Vietnamese version demonstrated appropriate translation, establishing its validity and reliability in measuring colorectal cancer-related concerns within the health-related quality of life among Vietnamese persons post-surgery. [ABSTRACT FROM AUTHOR]

Phytochemical research of Perilla frutescens aerial parts led to isolation of 12 secondary metabolites, including one new 3-benzoxepin glucoside, perillafrutoside A (1), one new megastigmane glycoside, perillafrutoside B (2), and 10 known compounds. Their chemical structures were identified based on 1D/2D NMR, HRESIMS, and ECD spectroscopic analyses. The structure of 2 was elucidated based on revision of the previously reported stereoisomer, (6R,9R)-blumenyl α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside. Evaluation of their antimicrobial effect revealed that compounds 1 and 5–11 inhibit Enterococcus faecalis growth, compounds 6, 7 and 9 suppress Staphylococcus aureus growth, whereas compounds 6 and 11 attenuate Candida albicans growth. This is the first report of the isolation of 3–5, 8–10 and 12 from the genus Perilla and the antimicrobial effect of compounds 3, 8 and 10. [ABSTRACT FROM AUTHOR]

Using various chromatographic separations, two new cembranoids, ehrenbergols F and G (1 and 2), along with three known analogs ehrenbergol D (3), (+)-isosarcophine (4) and sinulariol Z2 (5) were isolated from the soft coral Sarcophyton ehrenbergi. The structural elucidation was done by extensive analysis of the 1 D and 2 D NMR, HR-ESI-QTOF-MS as well as CD experiments. In addition, compounds 1 (IC50 of 38.38 ± 2.89 µM), 3 (IC50 of 37.14 ± 3.22 µM) and 4 (IC50 of 45.01 ± 2.49 µM) revealed moderate inhibitory activity on LPS-induced NO production in RAW264.7 cells, whereas 2 (IC50 of 73.32 ± 1.95 µM) and 5 (IC50 of 64.48 ± 4.93 µM) exhibited weak effect. [ABSTRACT FROM AUTHOR]