9 results on '"Thompson, P.M."'
Search Results
2. Lack of structural brain alteration associated with insomnia: Findings from the ENIGMA-Sleep working group
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Weihs, A., primary, Bi, H., additional, Bülow, R., additional, Eickhoff, S.B., additional, Ewert, R., additional, Frenzel, S., additional, Grabe, H.J., additional, Hoffstaedter, F., additional, Jahanshad, N., additional, Khazaie, H., additional, Patil, K., additional, Riemann, D., additional, Rostampour, M., additional, Schiel, J.E., additional, Spiegelhalder, K., additional, Stubbe, B., additional, Thomopoulos, S.I., additional, Thompson, P.M., additional, Valk, S.L., additional, Völzke, H., additional, Zarei, M., additional, and Tahmasian, M., additional
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- 2022
- Full Text
- View/download PDF
3. Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
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Sønderby, I.E., Ching, CRK, Thomopoulos, S.I., van der Meer, D., Sun, D., Villalon-Reina, J.E., Agartz, I., Amunts, K., Arango, C., Armstrong, N.J., Ayesa-Arriola, R., Bakker, G., Bassett, A.S., Boomsma, D.I., Bülow, R., Butcher, N.J., Calhoun, V.D., Caspers, S., Chow, EWC, Cichon, S., Ciufolini, S., Craig, M.C., Crespo-Facorro, B., Cunningham, A.C., Dale, A.M., Dazzan, P., de Zubicaray, G.I., Djurovic, S., Doherty, J.L., Donohoe, G., Draganski, B., Durdle, C.A., Ehrlich, S., Emanuel, B.S., Espeseth, T., Fisher, S.E., Ge, T., Glahn, D.C., Grabe, H.J., Gur, R.E., Gutman, B.A., Haavik, J., Håberg, A.K., Hansen, L.A., Hashimoto, R., Hibar, D.P., Holmes, A.J., Hottenga, J.J., Hulshoff Pol, H.E., Jalbrzikowski, M., Knowles, EEM, Kushan, L., Linden, DEJ, Liu, J., Lundervold, A.J., Martin-Brevet, S., Martínez, K., Mather, K.A., Mathias, S.R., McDonald-McGinn, D.M., McRae, A.F., Medland, S.E., Moberget, T., Modenato, C., Monereo Sánchez, J., Moreau, C.A., Mühleisen, T.W., Paus, T., Pausova, Z., Prieto, C., Ragothaman, A., Reinbold, C.S., Reis Marques, T., Repetto, G.M., Reymond, A., Roalf, D.R., Rodriguez-Herreros, B., Rucker, J.J., Sachdev, P.S., Schmitt, J.E., Schofield, P.R., Silva, A.I., Stefansson, H., Stein, D.J., Tamnes, C.K., Tordesillas-Gutiérrez, D., Ulfarsson, M.O., Vajdi, A., van 't Ent, D., van den Bree, MBM, Vassos, E., Vázquez-Bourgon, J., Vila-Rodriguez, F., Walters, G.B., Wen, W., Westlye, L.T., Wittfeld, K., Zackai, E.H., Stefánsson, K., Jacquemont, S., Thompson, P.M., Bearden, C.E., Andreassen, O.A., ENIGMA-CNV Working Group, ENIGMA 22q11.2 Deletion Syndrome Working Group, Bernard, M., Blackburn, N.B., Bøen, R., de Geus, E., de Zwarte, SMC, Forti, M.D., Frei, O., Fukunaga, M., Hehir-Kwa, J.Y., Hillegers, MHJ, Hoffmann, P., Homuth, G., Jahanshad, N., Koops, S., Kumar, K., Kikuchi, M., Le Hellard, S., Leu, C., Murray, R.M., Naerland, T., Nyberg, L., Ophoff, R.A., Pike, G.B., Sando, S.B., Shin, J., Shumskaya, E., Sisodiya, S.M., Steen, V.M., Teumer, A., Uhlmann, A., Wright, M.J., Antshel, K.M., Campbell, L.E., Crossley, N.A., Crowley, T.B., Daly, E., Fiksinski, A.M., Forsyth, J.K., Fremont, W., Goodrich-Hunsaker, N.J., Gudbrandsen, M., Jonas, R.K., Kates, W.R., Lin, A., McCabe, K.L., Moss, H., Murphy, D.G., Murphy, K.C., Owen, M.J., Ruparel, K., Simon, T.J., van Amelsvoort, T., and Vorstman, JAS
- Subjects
brain structural imaging ,copy number variant ,diffusion tensor imaging ,evolution ,genetics-first approach ,neurodevelopmental disorders ,psychiatric disorders - Abstract
The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors in human brain development and related cognitive, psychiatric and behavioral manifestations. To that end, the ENIGMA-CNV WG has collated CNV and magnetic resonance imaging (MRI) data from ~49,000 individuals across 38 global research sites, yielding one of the largest studies to date on the effects of CNVs on brain structures in the general population. The 22q-ENIGMA WG includes 12 international research centers that assessed over 533 individuals with a confirmed 22q11.2 deletion syndrome, 40 with 22q11.2 duplications, and 333 typically developing controls, creating the largest-ever 22q11.2 CNV neuroimaging data set. In this review, we outline the ENIGMA infrastructure and procedures for multi-site analysis of CNVs and MRI data. So far, ENIGMA has identified effects of the 22q11.2, 16p11.2 distal, 15q11.2, and 1q21.1 distal CNVs on subcortical and cortical brain structures. Each CNV is associated with differences in cognitive, neurodevelopmental and neuropsychiatric traits, with characteristic patterns of brain structural abnormalities. Evidence of gene-dosage effects on distinct brain regions also emerged, providing further insight into genotype-phenotype relationships. Taken together, these results offer a more comprehensive picture of molecular mechanisms involved in typical and atypical brain development. This "genotype-first" approach also contributes to our understanding of the etiopathogenesis of brain disorders. Finally, we outline future directions to better understand effects of CNVs on brain structure and behavior.
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- 2022
4. How do substance use disorders compare to other psychiatric conditions on structural brain abnormalities?
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Navarri, X., Afzali, M.H., Lavoie, J., Sinha, R., Stein, D.J., Momenan, R., Veltman, D.J., Korucuoglu, O., Sjoerds, Z.. Holst, R.J. van, Hester, R., Orr, C., Cousijn, J., Yucel, M., Lorenzetti, V., Wiers, R., Jahanshad, N., Glahn, D.C., Thompson, P.M., Mackey, S., and Conrod, P.J.
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- 2022
5. Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure
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Hoogman, M., van Rooij, D., Klein, M., Boedhoe, P., Ilioska, I., Li, T., Patel, Y., Postema, M.C., Zhang-James, Y., Anagnostou, E., Arango, C., Auzias, G., Banaschewski, T., Bau, CHD, Behrmann, M., Bellgrove, M.A., Brandeis, D., Brem, S., Busatto, G.F., Calderoni, S., Calvo, R., Castellanos, F.X., Coghill, D., Conzelmann, A., Daly, E., Deruelle, C., Dinstein, I., Durston, S., Ecker, C., Ehrlich, S., Epstein, J.N., Fair, D.A., Fitzgerald, J., Freitag, C.M., Frodl, T., Gallagher, L., Grevet, E.H., Haavik, J., Hoekstra, P.J., Janssen, J., Karkashadze, G., King, J.A., Konrad, K., Kuntsi, J., Lazaro, L., Lerch, J.P., Lesch, K.P., Louza, M.R., Luna, B., Mattos, P., McGrath, J., Muratori, F., Murphy, C., Nigg, J.T., Oberwelland-Weiss, E., O'Gorman Tuura, R.L., O'Hearn, K., Oosterlaan, J., Parellada, M., Pauli, P., Plessen, K.J., Ramos-Quiroga, J.A., Reif, A., Reneman, L., Retico, A., Rosa, PGP, Rubia, K., Shaw, P., Silk, T.J., Tamm, L., Vilarroya, O., Walitza, S., Jahanshad, N., Faraone, S.V., Francks, C., van den Heuvel, O.A., Paus, T., Thompson, P.M., Buitelaar, J.K., and Franke, B.
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ADHD ,ASD ,ENIGMA ,cortex ,neuroimaging ,subcortical volumes - Abstract
Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed and the heterogeneity of methods used. In 2013 and 2014, the ENIGMA-ADHD and ENIGMA-ASD working groups were respectively, founded with a common goal to address these limitations. Here, we provide a narrative review of the thus far completed and still ongoing projects of these working groups. Due to an implicitly hierarchical psychiatric diagnostic classification system, the fields of ADHD and ASD have developed largely in isolation, despite the considerable overlap in the occurrence of the disorders. The collaboration between the ENIGMA-ADHD and -ASD working groups seeks to bring the neuroimaging efforts of the two disorders closer together. The outcomes of case-control studies of subcortical and cortical structures showed that subcortical volumes are similarly affected in ASD and ADHD, albeit with small effect sizes. Cortical analyses identified unique differences in each disorder, but also considerable overlap between the two, specifically in cortical thickness. Ongoing work is examining alternative research questions, such as brain laterality, prediction of case-control status, and anatomical heterogeneity. In brief, great strides have been made toward fulfilling the aims of the ENIGMA collaborations, while new ideas and follow-up analyses continue that include more imaging modalities (diffusion MRI and resting-state functional MRI), collaborations with other large databases, and samples with dual diagnoses.
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- 2022
6. Concurrent antiepileptic and antipsychotic use moderates lithium’s effects on regional brain volumes: a mega-analysis from the ENIGMA-Bipolar Disorder Working Group
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King, S., Tronchin, G., Nabulsi, L., Thomopoulos, S.I., Fontana, E., Radua, J., Sim, K., Gruber, O., Yatham, L., Dannlowski, U., Kircher, T., Nenadic, I., Stein, F., Brosch, K., Howells, F., Haarman, B.C.M., Pomarol-Clotet, E., Vieta, E., Landen, M., Cannon, D., Alnæs, D., Westlye, L.T., Jaramillo, C. López, Soeiro-de-Souza, M. Gerhardt, Berk, M., Elvsåshagen, T., Roberts, G., Mitchell, P.B., Fullerton, J.M., Green, M.J., Quidé, Y., Hermesdorf, M., Berger, K., Soares, J., Satterthwaite, T., Savitz, J., Benedetti, F., Glahn, D., Hajek, T., Kuplicki, R., Gotlib, I.H., Amoretti, S., Sacchet, M., Favre, P., Van Rheenen, T., Karantonis, J. Anthony, Furlong, L., Forte, F., Rossell, S., Goldstein, B., Kennedy, K., Canales-Rodriguez, E., Lahud, E., Mwangi, B., Rodriguez-Cano, E., Salvador, R., Wu, M.-J., Houenou, J., Rodrigue, A., Melloni, E.M.T., Sponheim, S., Urosevic, S., Demro, C., Goya-Maldonado, R., Eyler, L., Thompson, P.M., Andreassan, O.A., Ching, C.R.K., and McDonald, C.
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- 2022
- Full Text
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7. P.0035 Structural brain correlates of childhood inhibited temperament
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Bas-Hoogendam, J.M., Bernstein, R., Benson, B.E., Salum, G.A., Pan, P.M., Jackowski, A.P., Bressan, R.A., Zugman, A., Degnan, K.A., Fox, N.A., Henderson, H.A., Tang, A., Zeytinoglu, S., Schwartz, C., Rauch, S.L., Felicione, J.M., Biederman, J., Rosenbaum, J.F., Hirshfeld-Becker, D.R., DeYoung, K.A., Shackman, A.J., Smith, J.F., Tillman, R.M., Buss, K.A., Gunther, K.E., Pérez-Edgar, K., Hill, S.Y., Battaglia, M., Tettamanti, M., Dougherty, L.R., Jin, F.J., Klein, D.N., Leung, H.C., Avery, S.N., Blackford, J.U., Clauss, J.A., Hayden, E.P., Liu, P., Vandermeer, M.R.J., Thompson, P.M., Westenberg, P.M., Van der Wee, N.J.A., Groenewold, N.A., Stein, D.J., Winkler, A.W., and Pine, D.S.
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Pharmacology ,Psychiatry and Mental health ,Neurology ,Pharmacology (medical) ,Neurology (clinical) ,Biological Psychiatry - Published
- 2021
8. Brain characteristics associated with anxiety disorders
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Groenewold, N.A., Bas-Hoogendam, J.M., Aghajani, M., Hilbert, K., Zugman, A., Fullana, M.A., Harrewijn, A., Cardinale, E.M., Roelofs, E., Laansma, M.A., Velzen, L.S. van, Thomopoulos, S.I., Jahanshad, N., Winkler, A.M., Thompson, P.M., Veltman, D.J., Lueken, U., Pine, D.S., Stein, D.J., and Wee, N.J.A. van der
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- 2021
9. P.0035 Structural brain correlates of childhood inhibited temperament: rationale and methodology for an ENIGMA-Anxiety mega-analysis
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Bas-Hoogendam, J.M., primary, Bernstein, R., additional, Benson, B.E., additional, Salum, G.A., additional, Pan, P.M., additional, Jackowski, A.P., additional, Bressan, R.A., additional, Zugman, A., additional, Degnan, K.A., additional, Fox, N.A., additional, Henderson, H.A., additional, Tang, A., additional, Zeytinoglu, S., additional, Schwartz, C., additional, Rauch, S.L., additional, Felicione, J.M., additional, Biederman, J., additional, Rosenbaum, J.F., additional, Hirshfeld-Becker, D.R., additional, DeYoung, K.A., additional, Shackman, A.J., additional, Smith, J.F., additional, Tillman, R.M., additional, Buss, K.A., additional, Gunther, K.E., additional, Pérez-Edgar, K., additional, Hill, S.Y., additional, Battaglia, M., additional, Tettamanti, M., additional, Dougherty, L.R., additional, Jin, F. Jingwen, additional, Klein, D.N., additional, Leung, H.C., additional, Avery, S.N., additional, Blackford, J.U., additional, Clauss, J.A., additional, Hayden, E.P., additional, Liu, P., additional, Vandermeer, M.R.J., additional, Thompson, P.M., additional, Westenberg, P.M., additional, Van der Wee, N.J.A., additional, Groenewold, N.A., additional, Stein, D.J., additional, Winkler, A.W., additional, and Pine, D.S., additional
- Published
- 2021
- Full Text
- View/download PDF
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