31 results on '"Testori T"'
Search Results
2. Increasing occlusal vertical dimension: decisional algorithm of the prosthetic treatment phases|Rialzo della dimensione verticale d’occlusione: algoritmo decisionale delle fasi del trattamento protesico
- Author
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Berzaghi, A., Nanni, M., Testori, T., Bortolini, S., and Consolo, U.
- Subjects
occlusal vertical dimension - increasing occlusal vertical dimension - Published
- 2023
3. Long-Term Results of Intraforaminal Immediately Loaded Implants and Posterior Mandibular Regrowth Evaluation in Severely Atrophic Mandibles
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Testori, T., Clauser, T., Scaini, R., Wang, H., and Del Fabbro, M.
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Dental Implants ,Male ,immediate implant loading ,Settore MED/50 - Scienze Tecniche Mediche Applicate ,Dental Implantation, Endosseous ,Alveolar Bone Loss ,implant survival ,General Medicine ,Alveolar Ridge Augmentation ,Mandible ,atrophic mandibles ,Implant-Supported ,Dental Prosthesis Design ,Dental Prosthesis, Implant-Supported ,Dental Restoration Failure ,Female ,Follow-Up Studies ,Humans ,Treatment Outcome ,Dental Prosthesis ,Dental Implantation ,Settore MED/28 - Malattie Odontostomatologiche ,Oral Surgery ,Endosseous - Abstract
The aim of this clinical study was to verify the predictability of the rehabilitation of extremely atrophic jaws with immediately loaded short implants and evaluate posterior mandibular regrowth.A cohort of consecutive fully edentulous patients wearing complete dentures in both arches was enrolled. Periodically, implant survival and prosthetic success were assessed. After informed consent, a subsample of 10 patients who had preoperative CBCT underwent a postoperative CBCT 1 year after immediate implant loading, and 3D superimpositions of pre- and postoperative images were performed. Linear measurements of bone height were performed at two sites in each hemimandible and, on the same sections, bone density according to the qualitative gray values (GVs) was analyzed in an area of 3 mmFifty-nine fully edentulous patients (31 females, 28 males) with Class VI atrophic mandibles according to Cawood and Howell were rehabilitated with the insertion of four to five short implants (4-mm diameter, 7- or 8.5-mm long). Overall, 251 implants were immediately loaded with a fixed hybrid prosthesis. Four patients did not show up for recall visits, bringing the final number down to 55 patients (31 females, 24 males) and 231 implants. In up to 14 years of follow-up, a total of 4 implant failures were recorded (cumulative survival rate, 98.4%). The biologic complications included 9 mucositis (3.9%) and 3 peri-implantitis (1.3%) at implant-level analysis. Mechanical complications involved 9 chippings of the prosthetic restorations (17.0%). In the 10-patient subsample, the analysis showed bone growth (average of 1.2 ± 0.7 mm) in the posterior areas of the mandible. In addition, bone density was found to increase 17% to 27% with reference to the preoperative CBCT.The immediate loading of short implants may represent a feasible therapeutic option for the treatment of fully edentulous patients with severely atrophic mandibles. Bone regrowth in the posterior areas and an increase in bone density of the mandible may occur.
- Published
- 2022
4. 3D Computed Tomography vs. 2D radiography: comparison of 3D direct anthropometry with 2D norm calculations and analysis of differences in soft tissue measurements.
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PERROTTI, G., GOKER, F., ROSSI, O., NOWAKOWSKA, J., RUSSILLO, A., BELTRAMINI, G., TARTAGLIA, G. M., TESTORI, T., DEL FABBRO, M., and MORTELLARO, C.
- Abstract
OBJECTIVE: The aim of this study was twofold: (1) to compare soft tissue measurements of the same distances obtained from 3D computed tomography reconstructions with 2D cephalometric radiograms, (2) to compare data from 3D measurements from direct anthropometry and 2D "norms" for the facial measurements. PATIENTS AND METHODS: A total of 40 Caucasian patients that had their CBCT scans for various dental and dentoskeletal reasons were enrolled in this study. All the patients had large field of view (from the forehead to the chin). The data were stored in DICOM format and imported into a software for 3D reconstructions. After 3D facial soft tissue model generation, the distances between 18 soft tissue points were measured. The 3D soft tissue analysis was performed, and the facial indices were calculated. The mean 3D values were compared with 2D measurements performed on lateral cephalograms and Arnett's and Farkas' norms. The measurements were statistically compared using Student's f-test. RESULTS: Assessments from 2D and 3D mea-surements showed no statistical difference except for the distance Pogonion (for both male and female) and Labial superius prominence (females) to the True Vertical Line in 2D /Plane in case of 3D measurements. There was a significant difference between all 3D measurements and Arnett's and anthropometric Farkas' "norms". The mean difference between Farkas' "norms" and 3D measurements was within 3 mm for 70% of measurements. CONCLUSIONS: According to the results, 3D soft tissue analysis allows for complete diagnostic determination. The 3D "norms" are to be verified on a greater sample. [ABSTRACT FROM AUTHOR]
- Published
- 2023
5. Riabilitazione della regione molare con elemento singolo implanto-supportato: considerazioni biomeccaniche e linee guida cliniche
- Author
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Bortolini, S, Berzaghi, A, Bianchi, A, Nanni, M, Testori, T, and Consolo, U.
- Published
- 2022
6. Discinesie orali e neurofisiologia della riabilitazione orale implanto-protesica
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Bortolini, S, Carta, G, Frugone-Zambra, R, Berzaghi, A, Bianchi, A, Nanni, M, Testori, T, and Consolo, U.
- Published
- 2022
7. Clinical and radiographic changes following transcrestal sinus augmentation: A scoping review of the last 25 years.
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Decker AM, Stuhr S, Testori T, and Wang HL
- Abstract
Introduction: Maxillary sinus floor elevation is a surgical procedure intended to increase the volume of the bone vertically to accommodate dental implant placement. This intervention is frequently required for implant installation in the posterior maxilla, where the bone may be insufficient for securing implants of necessary length and stability. Sinus floor elevation can be completed either through a direct approach with a "window" through the lateral wall of the alveolar ridge or an indirect "transcrestal/transalveolar" sinus floor elevation (TSFE), which accesses the sinus floor through the crest of the edentulous ridge. Our study aims to provide a comprehensive scoping review of research conducted over the past 25 years on TSFE, specifically., Methods: A literature search aimed at identifying pertinent literature for the purpose of this PRISMA-ScR-compliant scoping review was conducted. Only randomized controlled trials, non-randomized controlled trials, prospective cohort studies, and case series that met the eligibility criteria were selected. Relevant data from these studies were extracted. Primary outcome measures included radiographic bone levels and implant failure >5 years. Secondary outcome measures included implant stability at time of placement and complications. Interventions reported in the selected studies were grouped based on treatment modality, which were then compared with the control therapy (traditional osteotome technique) after a minimum of 12 months healing period., Results: Our search yielded 633 records, and after deduplication, 574 of these were screened. Application of the eligibility criteria led to the inclusion of 37 articles in the final selection. Case selection for included studies enrolling subjects: Four different transcrestal sinus elevation treatment modalities were identified: (a) osteotome, (b) piezoelectric surgery, (c) osseodensification, and (d) hydraulic techniques. Due to the heterogeneity of the studies, no superior approach for TSFE could be identified. Overall, all techniques demonstrated high implant survival rates., Conclusion: Comprehensive understanding of the patient's medical history, available armamentarium, and post-operative complications/management strategies are all essential to the completion of a successful TSFE approach for implant placement in the posterior maxilla, regardless of the treatment modality used., (© 2024 The Author(s). Clinical Implant Dentistry and Related Research published by Wiley Periodicals LLC.)
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- 2024
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8. Dental Evaluation: Oral Surgery-Related Complications.
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Scaini R, Berzaghi A, Saibene AM, Taschieri S, and Testori T
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The article provides an in-depth review focused on diagnosing oral surgery-related complications that may cause odontogenic sinusitis (ODS). It emphasizes the importance of evaluating patients with prior oral surgical procedures to determine whether the prior procedure is an ongoing infectious source of the ODS. Specifically, diagnostic evaluations will be described for detecting oroantral communications and fistulas, dental implant dislocation or protrusion, and whether implants and graft placed in maxillary sinuses are infected. It highlights the role of different oral examination techniques, optimal imaging modalities, and the importance of otolaryngologic collaboration to evaluate for infectious ODS., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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9. Mucosal cyst aspiration in conjunction with maxillary sinus elevation: A clinical cohort study.
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Testori T, Scaini R, Deflorian M, Taschieri S, Decker AM, Saleh M, Zuffetti F, Saibene AM, Felisati G, Wallace SS, Francetti L, Wang HL, and Del Fabbro M
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- Humans, Female, Male, Middle Aged, Cysts surgery, Cysts complications, Adult, Cohort Studies, Aged, Dental Implantation, Endosseous methods, Sinus Floor Augmentation methods, Maxillary Sinus surgery, Maxillary Sinus diagnostic imaging
- Abstract
Introduction: Patients with mucosal cysts in the maxillary sinus require special consideration in patients who require implant therapy for the restoration when undergoing implant therapy for the restoration of the posterior maxillary dentition. Treatment strategies for these clinical situations remain controversial in the literature. Thus, this study seeks to describe a safe and effective therapeutic strategy for sinus augmentation in patients with pre-existing maxillary antral cysts., Methods: A total of 15 patients and 18 sinuses were consecutively enrolled in this cohort study and underwent maxillary antral cyst treatment by needle aspiration and simultaneous maxillary sinus augmentation (MSA). During surgical procedures, threeimplants (Zimmer Biomet, Indiana, USA) were positioned in 11 sinuses and two implants (Zimmer Biomet, Indiana, USA) were positioned in 5 sinuses., Results: Overall implant success and survival rates were 100% and 97.8%, respectively at 1 year and 5-year follow-ups. Crestal bone resorption averaged 0.3 ± 0.2 mm 5-year post-loading, showing bone stability. Implant survival rate at 5-year follow-up expressed predictability of the technique comparable to historical data when MSA was performed alone. Crestal bone resorption averaged 0.3 ± 0.2 mm 5 years post-loading and shows bone stability utilizing mucosal cyst aspiration with concomitant MSA procedures. Quality of life evaluation at 1-week post-op showed similar results to published historical data. In 81% (13 sinuses), the CBCT examination at 5-year follow-up showed no cyst reformation, in 19% (3 sinuses) cyst reformation was visible, but smaller in size when compared to the pre-op CBCT evaluation, and all the patients were asymptomatic., Conclusions: Maxillary sinus mucosal cyst aspiration with concomitant MSA, may be a viable option to treat maxillary sinus cyst., (© 2024 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals LLC.)
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- 2024
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10. Maxillary sinus opacification after surgery in asymptomatic patients: Transient swelling of the sinus mucosa or graft dispersion into the maxillary sinus. A radiographic report of three cases after a follow-up period of at least 5 years.
- Author
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Testori T, Scaini R, Friedland B, Saibene AM, Felisati G, Craig JR, Deflorian M, Zuffetti F, Del Fabbro M, and Wang HL
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- Humans, Bone Transplantation methods, Bone Transplantation adverse effects, Dental Implantation, Endosseous adverse effects, Dental Implantation, Endosseous methods, Edema etiology, Edema diagnostic imaging, Edema pathology, Follow-Up Studies, Nasal Mucosa diagnostic imaging, Nasal Mucosa pathology, Postoperative Complications diagnostic imaging, Postoperative Complications etiology, Cone-Beam Computed Tomography, Maxillary Sinus surgery, Maxillary Sinus diagnostic imaging, Sinus Floor Augmentation adverse effects, Sinus Floor Augmentation methods
- Abstract
Maxillary sinus grafting is a predictable regenerative technique to facilitate maxillary posterior implant placement when there is insufficient vertical bone height inferior to the maxillary sinuses to allow placement of implants of adequate dimensions. It enables an increase in vertical bone height, which makes implant placement easier. Maxillary sinus mucosal membrane perforation is one of the most common intraoperative complications during maxillary sinus grafting and may result in extrusion of graft material into the sinus. When this occurs, the mucociliary function of the maxillary sinus may expel the extruded graft material through its natural ostium, though graft particles may remain in the sinus or possibly occlude the natural ostium. After grafting, transient maxillary sinus mucosal oedema may occur. A postoperative CBCT scan may reveal varying degrees of sinus opacification, namely partial, subtotal or total. Although it is always possible to identify graft material, which may enter the sinus as a result of membrane perforation that might not even be visible to the implantologist during the surgical procedure, it is challenging to assess whether sinus opacification is due to mucosal thickening or mucus accumulation. The aim of the present case series was to offer a pragmatic approach to managing asymptomatic patients whose CBCT scans demonstrated partial, subtotal or total maxillary sinus opacification with bone graft particles that seemed to have been extruded into the sinus.
- Published
- 2024
11. The biologically oriented preparation technique (BOPT) approach for preventing gingival recessions in fixed prosthodontics. A 5- to 13-year follow-up retrospective study.
- Author
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Galli F, Deflorian M, Zucchelli G, Del Fabbro M, and Testori T
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- Humans, Retrospective Studies, Follow-Up Studies, Male, Female, Middle Aged, Adult, Aged, Crowns, Gingival Recession prevention & control
- Abstract
Aim: The present study was a retrospective medium- to long-term follow-up assessment of the clinical outcomes of patients rehabilitated with fixed prostheses according to the biologically oriented preparation technique (BOPT) principles., Materials and Methods: Clinical records of patients rehabilitated between January 2007 and December 2014 were retrospectively assessed. Patients whose records met the inclusion criteria were also recalled for a hygiene visit. Data analyzed included the patients' periodontal condition, the presence of gingival recessions as well as any technical or biologic prosthetic complication., Results: Fifty-eight patients were recalled; of these, 52 patients who had received 220 crowns were available for the evaluation (the dropout being 13.8%). The average follow-up was 9.3 years (range 5 to 13 years): 14 patients (114 prosthetic crowns) had a follow-up between 5 and 8 years, and 36 patients (106 prosthetic crowns) between 9 and 13 years. The prosthetic survival rate was 99.6%. One radicular fracture (0.4%) and four chippings of the veneering porcelain (1.8%) were recorded. Six teeth (2.7% of the examined prosthetic crowns) presented gingival recession of < 1 mm, and 13 teeth (24 sites) had a pocket probing depth of 4 mm (5.9% of the prosthetic crowns/1.8% of the sites). Finally, 20 sites (1.5%) in seven teeth (3.2%) showed bleeding on probing., Conclusions: Tooth preparation according to the BOPT principles (ie, with a vertical finishing line) resulted in medium- to long-term periodontal health and stability of the gingival tissue, and prosthetic success was maintained.
- Published
- 2024
12. Novel Parameter in Pre-Surgical Orthodontic Preparation: A Retrospective Study on the Role of the Upper Incisor Position and a Morphological Evaluation of the Anterior Nasal Spine.
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Rossi O, Perrotti G, Del Fabbro M, and Testori T
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The position and inclination of the incisors play a crucial role in achieving optimal outcomes in orthodontic and orthognathic surgical treatment, given their impact on facial aesthetics. Background/objectives : Due to numerous distorting factors that affect the reliability of the ANB angle, the aim of the present work is to evaluate a more constant parameter over time, the anterior nasal spine (ANS), and explore whether aligning the incisal margin of the upper incisors with the anterior nasal spine could be a reliable indicator for achieving appropriate labial support in pre-surgical orthodontic preparation. Methods : From a pool of 500 cone beam computed tomography (CBCT) scans, 50 CBCT examinations displaying a Class 1 skeletal pattern (ANB = 2° ± 2°) with an intermediate (3.2-4 mm) or mixed (4-6 mm) sagittal maxillary position (MX), as determined by the 3D multiplanar total face approach (TFA), were selected and compared with CBCT examinations randomly chosen from the initial pool. Moreover, 12 landmarks were identified, and measurements were automatically obtained, using software, and recorded. Mean and standard deviation values were calculated for each sample. A comparison was made between the two samples, aligning the results with the morphological analysis of the anterior nasal spine and the sagittal position of the upper maxilla. Results : In Class 1 subjects, the distance between the incisal margin and the plane passed in relation to the anterior nasal spine should range between -1 mm and 1 mm, aligned with or slightly ahead of the anterior nasal spine or slightly ahead of this limit. Conclusions: The anterior nasal spine can serve as a reliable reference point for planning the position of the upper incisors, with excessive proclination or retroclination from this reference point deemed unacceptable.
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- 2024
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13. Current Emerging Concepts on the Pathogenesis of Peri-implant Diseases: A Narrative Review.
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Guarnieri R, Testarelli L, Galindo-Moreno P, Del Fabbro M, and Testori T
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Objectives: The aim of this narrative review is to describe the emerging evidence concerning etiological factors and pathophysiological mechanisms involved in peri-implant inflammatory diseases., Material and Methods: An electronic search for articles published until November 2022 was conducted in MEDLINE by three independent reviewers to identify manuscripts reporting data on etiological factors and pathophysiological mechanisms associated with peri-implant diseases., Results: Current evidence suggests that peri-implant mucositis and peri-implantitis are inflammatory conditions linked to a microbial challenge. However, in recent years, there has been increasing evidence indicating that certain peri-implant inflammatory conditions may not be primarily related to biofilm-mediated infectious processes but rather to other biological mechanisms, such as a foreign body response., Conclusion: The current evidence, not only in the dental literature, opens new avenues for a more complex interpretation of the etiopathogenetic factors involved in peri-implant diseases. A better understanding of various factors related to the host response, including dysbiosis mechanisms associated with changes in microbiota composition, is necessary for a more precise physiopathological characterization of these diseases.
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- 2024
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14. Indications for implant-supported rehabilitation of the posterior atrophic maxilla: A multidisciplinary consensus among experts in the field utilising the modified Delphi method.
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Testori T, Clauser T, Rapani A, Artzi Z, Avila-Ortiz G, Barootchi S, Bressan E, Chiapasco M, Cordaro L, Decker A, De Stavola L, Di Stefano DA, Felice P, Fontana F, Grusovin MG, Jensen OT, Le BT, Lombardi T, Misch C, Pikos M, Pistilli R, Ronda M, Saleh MH, Schwartz-Arad D, Simion M, Taschieri S, Toffler M, Tozum TF, Valentini P, Vinci R, Wallace SS, Wang HL, Wen SC, Yin S, Zucchelli G, Zuffetti F, and Stacchi C
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- Humans, Aged, Maxilla surgery, Consensus, Delphi Technique, Esthetics, Dental, Atrophy pathology, Dental Implants, Sinus Floor Augmentation methods
- Abstract
Purpose: To establish consensus-driven guidelines that could support the clinical decision-making process for implant-supported rehabilitation of the posterior atrophic maxilla and ultimately improve long-term treatment outcomes and patient satisfaction., Materials and Methods: A total of 33 participants were enrolled (18 active members of the Italian Academy of Osseointegration and 15 international experts). Based on the available evidence, the development group discussed and proposed an initial list of 20 statements, which were later evalu-ated by all participants. After the forms were completed, the responses were sent for blinded ana-lysis. In most cases, when a consensus was not reached, the statements were rephrased and sent to the participants for another round of evaluation. Three rounds were planned., Results: After the first round of voting, participants came close to reaching a consensus on six statements, but no consensus was achieved for the other fourteen. Following this, nineteen statements were rephrased and sent to participants again for the second round of voting, after which a consensus was reached for six statements and almost reached for three statements, but no consensus was achieved for the other ten. All 13 statements upon which no consensus was reached were rephrased and included in the third round. After this round, a consensus was achieved for an additional nine statements and almost achieved for three statements, but no consensus was reached for the remaining statement., Conclusion: This Delphi consensus highlights the importance of accurate preoperative planning, taking into consideration the maxillomandibular relationship to meet the functional and aesthetic requirements of the final restoration. Emphasis is placed on the role played by the sinus bony walls and floor in providing essential elements for bone formation, and on evaluation of bucco-palatal sinus width for choosing between lateral and transcrestal sinus floor elevation. Tilted and trans-sinus implants are considered viable options, whereas caution is advised when placing pterygoid implants. Zygomatic implants are seen as a potential option in specific cases, such as for completely edentulous elderly or oncological patients, for whom conventional alternatives are unsuitable.
- Published
- 2024
15. Use of the universal scan template to achieve a predictable optical impression: Preliminary data of a case series study in complete edentulous patients.
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Campana V, Papa A, Silvetti MA, Del Fabbro M, and Testori T
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- Humans, Preliminary Data, Dental Impression Technique, Models, Dental, Computer-Aided Design, Imaging, Three-Dimensional, Mouth, Edentulous diagnostic imaging, Mouth, Edentulous surgery, Dental Implants
- Abstract
Background: Full-arch IOS scan of edentulous areas rehabilitated with dental implants is nowadays still described as an unpredictable procedure. To improve the accuracy, a universal scan template (UST®) is proposed in this article. The clinician can easily assemble the template with a mechanical coupling, by matching the scan bodies with objects of known dimension characterized by specific markers. The UST® facilitates the scanning of an entire arch on scan bodies, reducing the learning curve, simplifying acquisition movements, shortening the scanning time, and drastically reducing the risk of distortions and aberrations of the scans., Materials and Methods: In a case series study on 12 patients, the improvement in the accuracy of the scans with UST® was validated by comparing the STL files derived from scans with and without the guide in place. A titanium bar was produced from each optical impression., Results: The bars obtained from the optical impressions taken without UST® were found to be nonpassive in the mouth in the majority of the cases. On the contrary with the use of UST® we obtained 12 passive prosthetic rehabilitations., Conclusions: The proposed solution may represent a valid method to improve the predictability of full arch optical impressions on implants., (© 2023 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals LLC.)
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- 2024
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16. Management of Advanced Peri-Implantitis by Guided Bone Regeneration in Combination with Trabecular Metal Fixtures, Two Months after Removal of the Failed Implants: Two-Year Results of a Single-Cohort Clinical Study.
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Bianconi S, Romanos G, Testori T, and Del Fabbro M
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Background: Implant replacement is among the treatment options for severe peri-implantitis. The aim of this single-cohort study was to evaluate the feasibility of replacing compromised implants affected by advanced peri-implantitis with new implants with a porous trabecular metal (TM) structure. Materials and Methods: Patients with one or more implants in the posterior region showing a defect depth >50% of implant length, measured from the residual crest, were consecutively included. Two months after implant removal, patients received a TM implant combined with a xenograft and a resorbable membrane. The implant stability quotient (ISQ) was measured at placement and re-assessed five months later (at uncovering), then after 6, 12, and 24 months of function. Marginal bone loss was radiographically evaluated. Results: Twenty consecutive cases were included. One patient dropped out due to COVID-19 infection, and nineteen cases were evaluated up to 24 months. At placement, the mean ISQ was 53.08 ± 13.65 (standard deviation), which increased significantly to 69.74 ± 9.01 after five months of healing ( p < 0.001) and to 78.00 ± 7.29 after six months of loading ( p < 0.001). Thereafter, the ISQ remained stable for up to 24 months (80.55 ± 4.73). All implants successfully osseointegrated and were restored as planned. After two years, the average marginal bone level change was -0.41 ± 0.38 mm (95% confidence interval -0.60, -0.21), which was limited yet significantly different from the baseline ( p < 0.05). Conclusions: The treatment of advanced peri-implant defects using TM implants inserted two months after explantation in combination with guided bone regeneration may achieve successful outcomes up to two years follow-up, even in the presence of low primary stability.
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- 2024
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17. Immediate placement and loading of implants with laser-microgrooved collar in combination with an anorganic porcine bone mineral matrix in the esthetic zone. Twelve-month results of a prospective multicenter cohort study.
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Rosano G, Testori T, Torrisi P, Invernizzi M, Vercellini N, and Del Fabbro M
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- Humans, Swine, Animals, Treatment Outcome, Cohort Studies, Follow-Up Studies, Prospective Studies, Quality of Life, Tooth Socket surgery, Tooth Extraction methods, Minerals therapeutic use, Esthetics, Dental, Immediate Dental Implant Loading methods, Dental Implants, Dental Implants, Single-Tooth
- Abstract
Background: Many techniques have been proposed to address post-extraction ridge resorption, which often represents a concern, especially in the esthetic region., Purpose: The purpose of the present, prospective, multicenter, single cohort study was to investigate, up to 1 year of function, the effectiveness of a protocol for alveolar ridge preservation involving implants with laser-microgrooved surface immediately placed in fresh extraction sockets., Materials and Methods: Twenty eight patients candidate to tooth extraction in the esthetic zone (site 15-25 and 35-45) were treated by immediate placement of a single laser-microgrooved implants with the adjunct of a highly porous anorganic porcine bone mineral matrix and a collagen wound dressing. Peri-implant marginal bone level (MBL) was evaluated at time of loading, 3 and 12 months after loading. Gingival index, plaque index, probing depth, and bleeding on probing were measured at 3, 6, and 12 months after loading. Dimensional changes at implant sites were digitally evaluated using the best-fit superimposition of pre-and post-socket preservation models. Implant aesthetic score (IAS) as well as patients' post-operative quality of life were also evaluated at 12 months. Comparisons between data relative to thick and thin gingival phenotypes were made using Student's t-test or Mann-Whitney test, as appropriate. The significance level was set at p = 0.05., Results: No patient dropped out, and 28 implants were evaluated at 12 months post-loading. The overall MBL was found to be 0.92 ± 1.11 mm. Volumetric analysis of superimposed models showed an alveolar bone tissue displacement at the buccal aspect of -0.57 ± 0.52 mm in thin phenotypes and -0.46 ± 0.31 mm in thick phenotypes (p = 0.58, unpaired Student's t-test). No signs of soft tissue recession or esthetically unpleasant buccal gingiva were reported., Conclusions: The clinical protocol herein employed showed benefits in maintaining marginal bone levels and soft tissue contour around post-extraction implants in the esthetic zone., (© 2023 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals LLC.)
- Published
- 2023
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18. Auto-dentin platelet-rich fibrin matrix is an alternative biomaterial for different augmentation procedures: A retrospective case series report.
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Alrmali A, Saleh MHA, Mazzocco J, Zimmer JM, Testori T, and Wang HL
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- Humans, Retrospective Studies, Bone Transplantation, Dentin, Biocompatible Materials, Platelet-Rich Fibrin
- Abstract
Objectives: Autologous dentin grafts derived from extracted teeth have shown promise as bone graft materials for promoting bone regeneration. This retrospective case series aimed to evaluate clinical, radiographic, and histologic outcomes of using autologous dentin matrices in various bone regeneration procedures., Materials and Methods: This case series included 26 eligible patients and encompassed 4 socket preservation cases, 5 cases of guided tissue regeneration, 5 cases of guided bone regeneration (GBR), 10 cases of sinus augmentation procedures, 2 immediate placement implants, and 2 socket shields. Dentin grafts were prepared from extracted teeth, cleaned, and processed. These grafts were combined with platelet-rich fibrin (PRF) to create adhesive dentin matrices, then covered with collagen membranes for simultaneous guided bone augmentation cases. Cone beam computed tomography (CBCT) scans were conducted before surgery and 4 months postoperatively to assess ridge dimensions. Histologic evaluation was performed through bone core biopsies for socket preservation cases at the 4-month mark., Results: A total of 42 implants were placed in 26 patients, with an average follow-up of 32 months. Notably, two implant failures occurred following lateral maxillary sinus augmentation. CBCT scans at the 4-month interval revealed bone coverage over implant platforms in the majority of cases. Histologic analysis from two cases of socket preservation demonstrated dentin granules enveloped by newly formed bone undergoing continuous remodeling. The quantitative histomorphometric assessment revealed a bone area of 42.8 ± 3.56%, a remaining graft area of 19.05 ± 4.58%, and a viable bone of 38.15 ± 7.84%., Conclusions: The utilization of autologous dentin particles mixed with PRF proved effective as an alternative to conventional bone graft materials in GBR and maxillary sinus augmentation procedures. Larger controlled clinical trials are recommended to further substantiate these findings., (© 2023 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.)
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- 2023
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19. Complications and treatment errors in peri-implant soft tissue management.
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Stefanini M, Marzadori M, Sangiorgi M, Rendon A, Testori T, and Zucchelli G
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- Humans, Dental Implantation, Endosseous adverse effects, Dental Implantation, Endosseous methods, Dental Implants adverse effects, Tooth, Mucositis
- Abstract
Inadequate quality, quantity, or aesthetics of the peri-implant soft tissues can result from a combination of factors related to the outcome of treatments performed before, during, or after implant placement. In this paper, we describe in detail the treatment errors that can pave the way for the onset of mucositis or give rise to soft tissue complications such as peri-implant soft tissue discoloration or dehiscence, graft exposure, or scar formation. By tracing the error back to the planning or surgical stage, clinical insights on surgical soft tissue management are provided to avoid or treat complications that affect the status of the peri-implant soft tissues. Mastering the learning curve and knowing the limitations of each technique are fundamental for preventing added treatment failures that can result in increased patient morbidity and overall discontent., (© 2023 The Authors. Periodontology 2000 published by John Wiley & Sons Ltd.)
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- 2023
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20. How to avoid intraoperative and postoperative complications in maxillary sinus elevation.
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Testori T, Tavelli L, Scaini R, Saibene AM, Felisati G, Barootchi S, Decker AM, Deflorian MA, Rosano G, Wallace SS, Zucchelli G, Francetti L, and Wang HL
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- Humans, Maxillary Sinus surgery, Postoperative Complications prevention & control, Postoperative Complications surgery, Risk Factors, Dental Implantation, Endosseous adverse effects, Dental Implantation, Endosseous methods, Sinus Floor Augmentation adverse effects, Sinus Floor Augmentation methods
- Abstract
Maxillary sinus floor elevation, via the lateral approach, is one of the most predictable bone augmentation procedures performed in implant dentistry. but both intra- and postoperative complications can occur, and some of them are severe. Our aim is as follows: To review the pertinent literature on the topic, especially assessing the risk factors related to complications. To give clinical recommendations to minimize intra- and postoperative complications with the ultimate scope of improving the standard of clinical care and patient safety., (© 2023 The Authors. Periodontology 2000 published by John Wiley & Sons Ltd.)
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- 2023
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21. Avoiding implant-related complications in medically compromised patients with or without unhealthy lifestyle/Elevated oxidative stress.
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Guabello G, Zuffetti F, Ravidà A, Deflorian M, Carta G, Saleh MHA, Serroni M, Pommer B, Watzek G, Francetti L, and Testori T
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- Humans, Aged, Postoperative Complications, Oxidative Stress, Dental Implantation, Endosseous methods, Dental Implants adverse effects, Tooth Loss
- Abstract
Increased human life expectancy broadens the alternatives for missing teeth and played a role in the widespread use of dental implants and related augmentation procedures for the aging population. Though, many of these patients may have one or more diseases. These systemic conditions may directly lead to surgical complications, compromise implant/bone healing, or influence long-term peri-implant health and its response to biologic nuisances. Offering patients credible expectations regarding intra- and postoperative complications and therapeutic prognosis is an ethical and legal obligation. Clear identification of potential types of adverse effects, complications, or errors is important for decision-making processes as they may be related to different local, systemic, and technical aspects. Therefore, the present review structures the underlying biological mechanisms, clinical evidence, and clinical recommendations for the most common systemic risk factors for implant-related complications., (© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Published
- 2023
- Full Text
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22. Soft tissue-related complications around anterior implants: commentary and clinical checklist.
- Author
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Fischer KR, Scaini R, Chackartchi T, Solderer A, Schmidlin PR, and Testori T
- Subjects
- Humans, Checklist, Esthetics, Dental, Dental Implants, Dental Implants, Single-Tooth
- Abstract
Implant-based rehabilitation is a clinical challenge, especially in the esthetic area. Numerous factors influence the outcome of the rehabilitation; however, the two main factors are the bone and soft-tissue deficiencies at the intended implant site. Peri-implant soft tissue complications can arise from a combination of factors that can be summarized as two categories: diagnostic errors and surgical planning management errors. Most of the complications can be corrected after each step of the treatment and even after the delivery of the prosthetic restoration with adequate soft tissue management in order to give the patient an esthetically pleasing outcome. The aims of this article were: to present the current literature, to propose a clinical checklist to guide clinicians in evaluating the prognosis of the treatment utilizing soft tissue grafting, and to illustrate a case series partially employing the proposed clinical checklist. The proposed checklist could be helpful in evaluating the prognosis of the treatment utilizing only soft tissue grafting. In clinical cases in which the prognosis is classified as good, soft tissue management could be a viable treatment option before attempting more radical procedures like implant removal.
- Published
- 2023
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23. Residual Bone Height and New Bone Formation after Maxillary Sinus Augmentation Procedure Using Biomaterials: A Network Meta-Analysis of Clinical Trials.
- Author
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Khijmatgar S, Del Fabbro M, Tumedei M, Testori T, Cenzato N, and Tartaglia GM
- Abstract
Background: Different factors may affect new bone formation following maxillary sinus floor augmentation for the rehabilitation of posterior edentulous maxilla. The purpose of this study was to determine the influence of residual bone height (RBH) on new bone formation after lateral sinus augmentation utilizing different biomaterials, through a network meta-analysis (NMA)., Methods: PUBMED, Scopus, and Web of Science electronic databases were searched until 31 December 2022 to obtain relevant articles. A hand search was also conducted. Randomised controlled studies on maxillary sinus augmentation comparing different grafting materials in patients with atrophic posterior maxilla, in need of prosthetic rehabilitation, were included. The risk of bias was assessed following the guidelines of the Cochrane Collaboration. The primary outcome was new bone formation (NBF), assessed histomorphometrically. The statistical analysis was performed by splitting the data according to RBH (<4 mm and ≥4 mm)., Results: A total of 67 studies were eligible for conducting NMA. Overall, in the included studies, 1955 patients were treated and 2405 sinus augmentation procedures were performed. The biomaterials used were grouped into: autogenous bone (Auto), xenografts (XG), allografts (AG), alloplasts (AP), bioactive agents (Bio), hyaluronic acid (HA), and combinations of these. An inconsistency factor (IF) seen in the entire loop of the XG, AP, and Bio+AP was found to be statistically significant. The highest-ranked biomaterials for the <4 mm RBH outcome were XG+AG, XG+AP, and Auto. Similarly, the surface under the cumulative ranking curve (SUCRA) of biomaterials for ≥4 mm RBH was Auto, Bio+XG, and XG+Auto., Conclusion: There is no grafting biomaterial that is consistently performing better than others. The performance of the materials in terms of NBF may depend on the RBH. While choosing a biomaterial, practitioners should consider both patient-specific aspects and sinus clinical characteristics.
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- 2023
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24. Radiographic protrusion of dental implants in the maxillary sinus and nasal fossae: A multidisciplinary consensus utilising the modified Delphi method.
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Testori T, Clauser T, Saibene AM, Artzi Z, Avila-Ortiz G, Chan HL, Chiapasco M, Craig JR, Felisati G, Friedland B, Gianni AB, Jensen OT, Lechien J, Lozada J, Misch CM, Nemcovsky C, Peacock Z, Pignataro L, Pikos MA, Pistilli R, Rasperini G, Scarfe W, Simion M, Stacchi C, Taschieri S, Trimarchi M, Urban I, Valentini P, Vinci R, Wallace SS, Zuffetti F, Del Fabbro M, Francetti L, and Wang HL
- Subjects
- Consensus, Delphi Technique, Humans, Maxillary Sinus diagnostic imaging, Dental Implants adverse effects, Sinusitis
- Abstract
The aim of the present study was to generate an international and multidisciplinary consensus on the clinical management of implant protrusion into the maxillary sinuses and nasal fossae. A total of 31 experts participated, 23 of whom were experts in implantology (periodontologists, maxillofacial surgeons and implantologists), 6 were otolaryngologists and 2 were radiologists. All the participants were informed of the current scientific knowledge on the topic based on a systematic search of the literature. A list of statements was created and divided into three surveys: one for all participants, one for implant providers and radiologists and one for otolaryngologists and radiologists. A consensus was reached on 15 out of 17 statements. According to the participants, osseointegrated implants protruding radiographically into the maxillary sinus or nasal fossae require as much monitoring and maintenance as implants fully covered by bone. In the event of symptoms of sinusitis, collaboration between implant providers and otolaryngologists is required. Implant removal should be considered only after pharmacological and surgical management of sinusitis have failed.
- Published
- 2022
25. Healing of Alveolar Sockets Treated with Concentrated Growth Factors: A Split-Mouth Study.
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Mozzati M, Tumedei M, Gallesio G, Menicucci G, Manzella C, Testori T, and Fabbro MD
- Abstract
Background: tooth extraction is a common procedure in oral surgery. The socket healing process involves hard and soft tissues and is characterized by intense remodeling, which may determine consistent dimension changes. Several autologous platelet concentrates (APCs) proved to be effective for enhancing alveolar socket healing after tooth extraction, accelerating socket closure and countering alveolar bone resorption. Concentrated growth factors (CGFs) are one of the most recently developed APCs, and their effect on the socket healing process still needs to be confirmed. Aim: The aim of the present split-mouth study was to evaluate the effectiveness of CGFs in enhancing the healing process in the postextraction alveolar socket and reducing postoperative pain. Methods: One hundred and fifty-four extractions were performed. One of the extraction sockets of each patient was treated with CGFs (test site), and the other socket was unfilled (control site). The main outcomes were: healing index, alveolar dimensions at the crestal level, socket closure, and pain perception. Descriptive statistics of the results were analyzed. Follow-up data were compared to baseline using paired tests. Results: The healing index on day 7 was significantly better (p < 0.001) in the test group (5.01 ± 1.30) as compared to the control group (6.65 ± 1.41). The mean visual analog scale for pain (VAS) was significantly higher for the control group when compared to the CGF group in the first 5 days postextraction. There was a trend toward greater socket closure in the CGF group, indicating faster healing, as compared to the control group at 7, 14, and 21 days. Conclusions: CGFs can represent a useful adjunctive tool, considering their mechanical and biological properties, for improving alveolar socket healing and reducing postoperative patient discomfort.
- Published
- 2022
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26. Low Window Sinus Elevation Technique: Bone Gain and Postsurgical Discomfort. A Retrospective Case Series.
- Author
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Zaniol T, Zaniol A, Ravazzolo S, Testori T, and Wallace SS
- Subjects
- Dental Implantation, Endosseous adverse effects, Dental Implantation, Endosseous methods, Humans, Maxilla surgery, Maxillary Sinus surgery, Pain surgery, Prospective Studies, Retrospective Studies, Dental Implants, Sinus Floor Augmentation adverse effects, Sinus Floor Augmentation methods
- Abstract
Recently, the Low Window technique was proposed to facilitate sinus augmentation and reduce postsurgical patient discomfort. It was shown to be both safe and effective. This case series evaluates the postsurgical discomfort of patients undergoing Low Window sinus augmentation, the bone gain achieved, and whether these factors correlate with the osteotomy area. Records of patients (n = 26) who underwent a sinus elevation using the Low Window approach (n = 34 interventions), followed by implant placement and prosthetic rehabilitation (n = 97 implants), were assessed retrospectively. The analyzed outcomes were the medial, middle, and lateral bone gain ≥ 9 months after augmentation; pain at 5 to 6 hours postsurgery, evaluated on a visual analog scale (VAS; 0 to 100); pain, swelling, and hematoma formation every day up to 7 days postsurgery, evaluated by VAS; implant and prosthetic success and survival rates; and rate of complications. The average follow-up time was 62.1 ± 14.9 months. No intraoperative sinus membrane perforations or other complications occurred. Medial, middle, and lateral bone gains were 10.1 ± 1.7 mm, 11.6 ± 0.8 mm, and 10.7 ± 0.9 mm, respectively. At the last follow-up, the implant success rate was 99%. Postsurgical VAS pain 5 to 6 hours postsurgery was 12.3 ± 8.0 and decreased significantly thereafter. Swelling prevalence was 29.4% at 1 day postsurgery, 20.6% at 2 days, and 2.9% the following day. No swelling was observed from day 4 onward. Prevalence of hematoma was 8.8% for 2 days postsurgery, 2.9% the day after, and no hematoma was observed thereafter. Only the osteotomy area correlated with immediate postsurgical pain, but not with other discomfort outcomes or with bone gain. Low Window sinus elevation might allow bone gain and medium-term implant and prosthetic success rates similar to that of other access window designs. Prospective, comparative studies are needed to investigate whether the technique is more advantageous than traditional approaches.
- Published
- 2022
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27. The Buccally Displaced Palatal (BDP) Flap to Increase Quantity and Thickness of Peri-implant Soft Tissue.
- Author
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Testori T, Deflorian M, Scaini R, Wang IC, Zucchelli G, Steigmann M, Del Fabbro M, Wang HL, and Francetti L
- Subjects
- Dental Plaque Index, Humans, Maxilla surgery, Mucous Membrane, Surgical Flaps, Dental Implants
- Abstract
Common challenges encountered for atrophic maxilla rehabilitation are the inadequate width and height of attached keratinized mucosa (AKM) and shallow vestibular depth. This study presents a buccally displaced palatal (BDP) flap technique to increase the tissue thickness and AKM width at the second-stage surgery and reestablish the correct fornix depth. The peri-implant pocket depths, modified Plaque Index score, modified sulcus Bleeding Index score, and soft tissue recession were evaluated 6 and 12 months after prostheses loading. A total of 52 implants were placed and analyzed, and no implant failures were found. No significant changes in peri-implant parameters were observed between 6 and 12 months, and mean recession was less than 0.2 mm after 12 months. Though this change was statistically significant, it was clinically irrelevant. The results demonstrate that adequately healthy peri-implant soft tissues and substantial dimensional stability of vestibular soft tissues at the 1-year follow-up were achieved with the BDP flap technique. The BDP flap could represent a viable option for increasing the width and the height of AKM and establishing the correct maxillary fornix depth.
- Published
- 2022
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- View/download PDF
28. Split-Thickness Flap for the Management of a Maxillary Sinus Wall Bony Fenestration During Lateral Window Sinus Augmentation: Case Reports and Technical Surgical Notes.
- Author
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Testori T, Yu SH, Scaini R, Rosano G, Tavelli L, Del Fabbro M, Francetti L, and Wang HL
- Subjects
- Alveolar Process, Humans, Maxilla diagnostic imaging, Maxilla surgery, Surgical Flaps, Tooth Extraction, Maxillary Sinus diagnostic imaging, Maxillary Sinus surgery, Sinus Floor Augmentation methods
- Abstract
Maxillary sinus wall fenestration at the lateral wall or floor of the sinus can result from many potential factors, such as the repair of oro-antral communication, Caldwell-Luc antrostomy, tooth extraction after an endodontic or periodontal infection that eroded the sinus wall, and the combination of sinus pneumatization and alveolar ridge resorption after teeth removal. When sinus wall fenestration is observed on radiographs, it usually indicates adhesion between the sinus membrane and buccal flap, which makes the reentry surgery for subsequent sinus augmentation challenging. To minimize surgical complications in these challenging scenarios, this paper presents a split-flap surgical technique for the management of soft tissue adhesion between the sinus membrane and alveolar mucosa when attempting a lateral window sinus augmentation.
- Published
- 2022
- Full Text
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29. Risk of early implant failure in grafted and non-grafted sites: A systematic review and meta-analysis.
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Clauser T, Lin GH, Lee E, Del Fabbro M, Wang HL, and Testori T
- Subjects
- Bone Transplantation adverse effects, Humans, Dental Implantation, Endosseous methods, Dental Implants adverse effects
- Abstract
Purpose: To assess whether bone grafting is associated with early implant failure (defined as a lack of osseointegration detected prior to functional loading) and to evaluate the association between bone grafting procedures and other risk factors for early implant failure., Materials and Methods: Two independent reviewers conducted an electronic search of MEDLINE (via PubMed). Meta-analysis was performed for the odds ratio of bone grafting procedures associated with early implant failure. The Newcastle-Ottawa Scale for cohort studies was used to assess the risk of bias., Results: Of the 231 articles selected for full-text review, 10 were included in the qualitative analysis and for quantitative meta-analysis. An odds ratio of 1.50 (95% confidence interval 1.06-2.13) was recorded for bone grafting procedures associated with early implant failure. Data regarding the association of bone grafting and other risk factors in determining early implant failure were insufficient for quantitative analysis., Conclusions: Within the limitations of this study, a significant positive association was found between bone grafting procedures and early implant failure. The possible negative effect of bone grafting procedures on implant osseointegration should be considered when planning implant therapy.
- Published
- 2022
30. Long-Term Results of Intraforaminal Immediately Loaded Implants and Posterior Mandibular Regrowth Evaluation in Severely Atrophic Mandibles.
- Author
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Testori T, Clauser T, Scaini R, Wang HL, and Del Fabbro M
- Subjects
- Dental Implantation, Endosseous adverse effects, Dental Implantation, Endosseous methods, Dental Prosthesis Design, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Female, Follow-Up Studies, Humans, Male, Mandible surgery, Treatment Outcome, Alveolar Bone Loss diagnostic imaging, Alveolar Bone Loss etiology, Alveolar Bone Loss surgery, Alveolar Ridge Augmentation methods, Dental Implants adverse effects
- Abstract
Purpose: The aim of this clinical study was to verify the predictability of the rehabilitation of extremely atrophic jaws with immediately loaded short implants and evaluate posterior mandibular regrowth., Materials and Methods: A cohort of consecutive fully edentulous patients wearing complete dentures in both arches was enrolled. Periodically, implant survival and prosthetic success were assessed. After informed consent, a subsample of 10 patients who had preoperative CBCT underwent a postoperative CBCT 1 year after immediate implant loading, and 3D superimpositions of pre- and postoperative images were performed. Linear measurements of bone height were performed at two sites in each hemimandible and, on the same sections, bone density according to the qualitative gray values (GVs) was analyzed in an area of 3 mm
2 including the cortical mandibular bone., Results: Fifty-nine fully edentulous patients (31 females, 28 males) with Class VI atrophic mandibles according to Cawood and Howell were rehabilitated with the insertion of four to five short implants (4-mm diameter, 7- or 8.5-mm long). Overall, 251 implants were immediately loaded with a fixed hybrid prosthesis. Four patients did not show up for recall visits, bringing the final number down to 55 patients (31 females, 24 males) and 231 implants. In up to 14 years of follow-up, a total of 4 implant failures were recorded (cumulative survival rate, 98.4%). The biologic complications included 9 mucositis (3.9%) and 3 peri-implantitis (1.3%) at implant-level analysis. Mechanical complications involved 9 chippings of the prosthetic restorations (17.0%). In the 10-patient subsample, the analysis showed bone growth (average of 1.2 ± 0.7 mm) in the posterior areas of the mandible. In addition, bone density was found to increase 17% to 27% with reference to the preoperative CBCT., Conclusion: The immediate loading of short implants may represent a feasible therapeutic option for the treatment of fully edentulous patients with severely atrophic mandibles. Bone regrowth in the posterior areas and an increase in bone density of the mandible may occur.- Published
- 2022
- Full Text
- View/download PDF
31. Late Maxillary Sinus Graft Infections Due to Peri-implantitis: Case Reports with Histologic Analysis.
- Author
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Testori T, Wang HL, Wallace SS, Piattelli A, Iezzi G, Tavelli L, Tumedei M, Vinci R, and Del Fabbro M
- Subjects
- Humans, Maxillary Sinus diagnostic imaging, Maxillary Sinus surgery, Dental Implants adverse effects, Maxillary Sinusitis diagnostic imaging, Maxillary Sinusitis etiology, Maxillary Sinusitis surgery, Peri-Implantitis etiology, Sinus Floor Augmentation adverse effects
- Abstract
Maxillary sinus grafting is generally a safe procedure. However, intraoperative complications, as well as early and late postoperative complications, may occur. Included in the latter group are graft infections that can be triggered by peri-implantitis. The aim of the present study was to report three cases of late maxillary sinus graft infections and to histologically evaluate the effects of peri-implantitis in the grafted area. In peri-implantitis cases in grafted sinuses, the sole removal of the implant along with accompanying debridement of the infected area may not be sufficient to resolve the infection, and a more-aggressive treatment may be necessary.
- Published
- 2021
- Full Text
- View/download PDF
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