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Your search keyword '"Sun, Chuxuan"' showing total 12 results
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12 results on '"Sun, Chuxuan"'

2. Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.

Author

Iorgulescu, J, Sun, Chuxuan, Neff, Corey, Cioffi, Gino, Gutierrez, Catherine, Kruchko, Carol, Ruhl, Jennifer, Waite, Kristin, Negoita, Serban, Hofferkamp, Jim, Tihan, Tarik, McLendon, Roger, Brat, Daniel, Ostrom, Quinn, and Barnholtz-Sloan, Jill

Subjects
CBTRUS, IDH, biomarkers, brain tumor, molecular epidemiology, Young Adult, Adolescent, Child, Humans, United States, Brain Neoplasms, Glioma, Astrocytoma, Glioblastoma, Biomarkers, Isocitrate Dehydrogenase, Mutation
Abstract

BACKGROUND: Selected molecular biomarkers were incorporated into the US cancer registry reporting for patients with brain tumors beginning in 2018. We investigated the completeness and validity of these variables and described the epidemiology of molecularly defined brain tumor types. METHODS: Brain tumor patients with histopathologically confirmed diagnosis in 2018 were identified within the Central Brain Tumor Registry of the United States and NCIs Surveillance, Epidemiology, and End Results Incidence databases. The brain molecular markers (BMM) site-specific data item was assessed for coding completeness and validity. 1p/19q status, MGMT promoter methylation, WHO grade data items, and new ICD-O-3 codes were additionally evaluated. These data were used to profile the characteristics and age-adjusted incidence rates per 100 000 population of molecularly defined brain tumors with 95% confidence intervals (95% CI). RESULTS: BMM completeness across the applicable tumor types was 75%-92% and demonstrated favorable coding validity. IDH-wildtype glioblastomas incidence rate was 1.74 (95% CI: 1.69-1.78), as compared to 0.14 for WHO grade 2 (95% CI: 0.12-0.15), 0.15 for grade 3 (95% CI: 0.14-0.16), and 0.07 for grade 4 (95% CI: 0.06-0.08) IDH-mutant astrocytomas. Irrespective of WHO grade, IDH mutation prevalence was highest in adolescent and young adult patients, and IDH-mutant astrocytomas were more frequently MGMT promoter methylated. Among pediatric-type tumors, the incidence rate was 0.06 for H3K27M-mutant diffuse midline gliomas (95% CI: 0.05-0.07), 0.03 for SHH-activated/TP53-wildtype medulloblastomas (95% CI: 0.02-0.03), and

Published
2022

6. Association Between Urbanicity and Outcomes Among Patients with Spinal Cord Ependymomas in the United States

Author

Sperber, Jacob, primary, Owolo, Edwin, additional, Abu-Bonsrah, Nancy, additional, Neff, Corey, additional, Baeta, Cesar, additional, Sun, Chuxuan, additional, Dalton, Tara, additional, Sykes, David, additional, Bishop, Brandon L., additional, Kruchko, Carol, additional, Barnholtz-Sloan, Jill S., additional, Walsh, Kyle M., additional, Larry Lo, Sheng-Fu, additional, Sciubba, Daniel, additional, Ostrom, Quinn T., additional, and Goodwin, C. Rory, additional

Published
2023
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7. Changing places: Longitudinal trends in living arrangements of persons living with dementia.

Author

White, Lindsay L. Y., Sun, Chuxuan, and Coe, Norma B.

Subjects
*CROSS-sectional method, *COMMUNITY health services, *INSURANCE, *RESIDENTIAL patterns, *MEDICARE, *FUNCTIONAL status, *DESCRIPTIVE statistics, *NURSING care facilities, *MEDICAID, *DATA analysis software, *NEEDS assessment, *DEMENTIA patients, *WELL-being, *ALGORITHMS, *COVID-19 pandemic, *RESIDENTIAL care, *OLD age
Abstract

The article presents a study which examined longitudinal trends in the living arrangements of persons living with dementia (PLWD) and the characteristics of PLWD in each care setting. Topics discussed include proportion of persons living with dementia in each living arrangement over time, and factors that may have altered where PLWD reside.

Published
2024
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9. How Physician Self-Perceptions Affect the Impact of Peer Comparison Feedback on Opioid Prescribing

Author

Liao, Joshua M., primary, Sun, Chuxuan, additional, Yan, Xiaowei S, additional, Patel, Mitesh S., additional, Small, Dylan S., additional, Isenberg, William M., additional, Landa, Howard M., additional, Bond, Barbara L., additional, Rareshide, Charles A.L., additional, Volpp, Kevin G., additional, Delgado, M. Kit, additional, Lei, Victor J., additional, Shen, Zijun, additional, and Navathe, Amol S., additional

Published
2023
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10. Corrigendum to: Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States

Author

Iorgulescu, J Bryan, primary, Sun, Chuxuan, additional, Neff, Corey, additional, Cioffi, Gino, additional, Gutierrez, Catherine, additional, Kruchko, Carol, additional, Ruhl, Jennifer, additional, Waite, Kristin, additional, Negoita, Serban, additional, Hofferkamp, Jim, additional, Tihan, Tarik, additional, McLendon, Roger, additional, Brat, Daniel J, additional, Ostrom, Quinn T, additional, and Barnholtz-Sloan, Jill S, additional

Published
2022
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