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In this work, we prepared a spherical CeO2/GO/c-MWCNT (Cerium oxide/Graphene oxide/Multiwalled Carbon nanotube) nanocomposite whose surface morphology looks porous and fibrous. The stacked layer of GO and c-MWCNT was stuffed with porous aminatedCeO2nanoparticles (NPs). Their physio-chemico aspects were probed using X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR) analysis. In addition, proposed porous CeO2/GO/c-MWCNT hybrid nanosystem, cisplatin-loaded CeO2/GO/c-MWCNT hybrid system (CeO2/CDDP-GO/c-MWCNT) and cisplatin (CDDP) was subjected to HeLa cells to examine % cell inhibition under a suitable in-vitro microenvironment. % Cell Inhibition at 1000 µg/mL of CeO2/CDDP-GO/c-MWCNT system was found to be of 91.82% and for 7.8 µg/mL concentration, it was found to be 61.41% on HeLa cell lines. CeO2/GO/c-MWCNT system has achieved 99.96% encapsulation efficiency with cisplatin drug. Hence, Cytotoxicity results are more significant for CeO2/CDDP-GO/c-MWCNT when compared to CeO2/GO/c-MWCNT system. Further, the developed CeO2/CDDP-GO/c-MWCNT hybrid nanosystem was taken up for Acridine Orange/Ethidium Bromide (AO/EB) dual fluorescence staining study to record the morphology assisted variations in both live and dead cells using fluorescence spectroscopy. Later, a flow cytometry study was performed to monitor the cell cycle at which the maximum cells were dead. In the current work, at the first stage (R1) the CeO2/CDDP-GO/c-MWCNT system was able to kill 3,76,659 cells in a cell culture medium that has a total volume of 4,91,748 HeLa cells at a lower concentration of 15.6 µg/mL. Based on the observations from the present in-vitro investigations, the developed CeO2/CDDP-GO/c-MWCNT hybrid nanosystem can be used as therapeutic platform for cervical cancer. [ABSTRACT FROM AUTHOR]

A compact single-layer frequency-selective surface (FSS) covering X-band frequency range for shielding application is presented in this study. The proposed FSS structure, constructed with a convoluted element printed on both sides of FR4 material, exhibits band-stop response covering a frequency spectrum of 8–12 GHz at 10 dB level of insertion loss. The designed FSS provides polarization-independent performance and good angular stability. The simulated result and the measured results seem to be in a good agreement. [ABSTRACT FROM AUTHOR]

In this study, simultaneous analysis on electrochemical detection of SMX and TMP in tablet formulation has been made using graphene oxide (GO) and ZnO QDs (GO-ZnO QDs) based nanocomposite modified glassy carbon electrode (GCE). The functional group presence was observed using FTIR study. The electrochemical characterization for GO, ZnO QDs and GO-ZnO QDs was studied using cyclic voltammetry using [Fe(CN) 6 ] 3- medium. In order to estimate the electrochemical redox behavior of SMX and TMP from tablet, the developed electrodes GO/GCE, ZnO QDs/GCE and GO-ZnO QDs/GCE are initially tested for electrochemical activity towards the SMX tablet in BR pH 7 medium. Later their electrochemical sensing has been monitored using square wave voltammetry (SWV). On observing the characteristic behavior of developed electrodes, GO/GCE exhibited detection potential of +0.48 V for SMX and +1.37 V for TMP whereas, ZnO QDs/GCE with +0.78V for SMX and for TMP 1.01 V respectively. Similarly, for GO-ZnO QDs/GCE, its 0.45 V for SMX and 1.11 V for TMP are observed using cyclic voltammetry. The obtained potential results on detecting SMX and TMP are in good agreement with previous results. Under optimized conditions, the response has been monitored with linear concentration range 50 μg/L to 300 μg/L for GO/GCE, ZnO QDs/GCE and GO-ZnO QDs/GCE in SMX tablet formulations. Their detection limits for the individual detection using GO-ZnO/GCE for SMX and TMP are found to be 0.252 ng/L and 19.10 μg/L and for GO/GCE it was 0.252 pg/L and 2.059 ng/L respectively. It was observed that ZnO QDs/GCE could not provide the electrochemical sensing towards SMX and TMP which may be due to the ZnO QPs can act as a blocking layer impeding the electron transfer process. Thus, the sensor performance lead to promising biomedical applications in real-time monitoring on evaluating selective analysis with SMX and TMP in tablet formulations., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

An integrated 1D/0D/1D hybrid nanomaterial was prepared from MWCNT supported carbon quantum dots @ MnO 2 nanomaterial for a sensitive and selective electrochemical heavy metal ion sensor by hydrothermal methods. The developed nanomaterials were characterized by various analytical methods such as FESEM, HRTEM, XRD, FTIR, EDX and elemental mapping study, and also its electrochemical properties of the prepared samples were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) analysis. Differential pulse voltammetry (DPV) analysis has been used to investigate the quantitative detection of heavy metal ions such as cadmium and chromium on modified electrodes under optimal conditions. The in-situ electrochemical sensitivity and selectivity of the samples were determined by varying various parameters, such as the concentration of heavy metal ions, different electrolytes and electrolyte pH. The observed DPV results show that prepared MWCNT (0.05 wt%) and CQD (0.1 wt%) supported MnO 2 nanoparticles show effective detection response for chromium (IV) metal ion. In particular, 0D CQD, 1D MWCNT, and MnO 2 hybrid nanostructures produced a synergistic effect among them, resulting in strong electrochemical performance of the prepared samples against the target metal ions., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Inc. All rights reserved.)

Graphene Oxide-Zinc Oxide (GO-ZnO) - a new nanomaterial that has queued the interest of researchers. Their intriguing promising physical and electrochemical features of electrode material have led to its widespread use in electrochemical sensor applications. GO-ZnO based nanomaterial were extensively exploited in the construction of electrochemical sensors due to their adaptability and distinct qualities. On understanding the structural role of these materials, their modification processes are critical for realizing their full potential. The advancement of technology on new concepts and strategies has revolutionized the field of sensor devices with high sensitivities and selectivity. These tools can test a range of contaminants quickly, accurately, and affordably while performing automated chemical analysis in complicated matrices. This paper highlights the electrochemical transducer surface for sensing various analytes and current research activity on GO-ZnO nanocomposite. Additionally, we talked about current developments in GO-ZnO nanostructured composites to identify relevant analytes (i.e., Nitrophenols, Antibiotic Drugs, Biomolecules). While being used in the laboratory, the majority of produced systems have proven to bring about excellent gains. Their monitoring application still has a long way to go before it is fixed due to problems like technological advancements and multifunctional strategies to get around the challenges for improving the sensing systems., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Surface water contamination of sulfamethoxazole (SMX) has tremendously affected the ecosystem. A primary study was performed to develop an electrochemical sensor for the determination of SMX. Overcoming the demerit associated with the conventional techniques, an electrochemical method was developed using GO/ZnO nanocomposite modified electrode to detect SMX in 0.1 M phosphate buffer (pH-5.5) buffer solution. The GO, ZnO and GO/ZnO nanocomposite were prepared using modified Hummer's, precipitation and sonochemical methods, respectively. Physico-chemical properties of all the materials and its modified electrode were analysed. Comparison was made by studying the SMX sensing performance of electrodes modified with GO, ZnO and GO/ZnO nanocomposites. Out of which GO/ZnO nanocomposite exhibited excellent sensing performance with the concentration range from 0.10 × 10 -6 to 1.5 × 10 -6  M with the limit of detection (LOD) 28.9 nM. The parameters such as electrolyte, effect of pH, scan rate were optimized for effective sensing performance. From the optimized results 0.1 M phosphate buffer was found to be a suitable electrolyte and the pH 5.5 was found to be appropriate to sense SMX at the scan rate 50 mVs -1 . Under optimized condition, the Differential Pulse Voltammetry (DPV) and Amperometry techniques were adopted for electrochemical sensing of SMX under static and hydrodynamic condition. The developed method was successfully tested for real time analysis for the samples collected from waste water treatment plant., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

The electrochemical behavior of sulfamethoxazole (SMX) was investigated on the surface of the glassy carbon electrode with Nafion coated GO, ZnO, GO-ZnO nanocomposites using cyclic voltammetry (CV). The results of voltammetric studies exhibited a considerable increase in background current on SMX detection at nafion coated GO-ZnO nanocomposite GC electrodes. However, the adopted fabrication procedure for GC electrodes was reported previously but only difference is nafion was drop casted over the fabricated nanocomposite electrode. In order to investigate the electrochemical performance behavior of GO/GCE, ZnO/GCE, GO-ZnO/GCE, variation on ZnO amounts with Nafion coated and uncoated GO/GC electrodes were involved and it was analyzed using cyclic voltammetry in 5 mM K 2 FeCN 6 using 0.1 M KCl solution electrolyte medium. In GO-ZnO/GC electrode, peak currents got reduced when compared with GO/GC electrode but their potential voltage difference (peak-to-peak) separation was increased. Similar results was observed for nafion coated GO-ZnO/GC electrode. On comparing the electrochemical process, the importance of nafion coated GO-ZnO nanocomposites were studied and proceeded with optimized amounts of modifier on the electrode surface for SMX detection. Thus Nf/GO-ZnO with different ZnO ratios performance showed significant response on determining SMX, resulting to progress as electrode sensor for health-care applications., (Copyright © 2022 Elsevier Ltd. All rights reserved.)

Sulfamethoxazole (SMX) forms the high harmfulness and causing negative health impacts to well-being human and environment that found to be major drastic concern. It is subsequently important to keep in track for monitoring of SMX through convenient detecting devices which include the requirement of being minimal expense and potential for on location environmental applications. Nanomaterials based design has been proposed to determine the SMX antibiotic which in turn provides the solution for this issue. In spite of the critical advancement accomplished in research, further endeavors are yet to foster the progress on electrochemical sensors with the guide of various functional nanomaterials and guarantee the effective transportability for such sensors with improved coherence. Moreover, it has been noticed that, only few reports on electrochemical sensing of SMX detection using nanomaterials was observed. Hence an in-depth evaluation of electrochemical sensing systems using various nanomaterials for SMX detection was summarized in this review. Additionally this current review centers with brief presentation around SMX hazard evaluation followed by study on the current logical techniques to feature the importance for SMX detection. This review will provide the sum up view towards the future ideas of this field which assists in improving the detecting strategies for SMX detection., (Copyright © 2021 Elsevier Ltd. All rights reserved.)