Search

The article focuses on how a standardized extract of Equisetum arvense (EQ) administered to geriatric mice delays the onset of osteosarcopenia, a condition characterized by the simultaneous deterioration of bone and skeletal muscle tissues associated with aging.

The article focuses on how V. macrocarpon, a standardized dry extract, can prevent the detrimental effects on muscles induced by a Western diet and cancer by reducing advanced glycation end-products (AGEs) in vitro.

The article focuses on cancer cachexia, a syndrome causing severe weight loss and muscle atrophy in cancer patients, and demonstrates that inhibiting the receptor for advanced glycation end-products (RAGE) with papaverine could be a promising pharmacological strategy to counteract cancer-induced.

The article focuses on investigating the role of the receptor for advanced glycation end-products (RAGE) in cancer cachexia, revealing that overexpression of RAGE in cancer cells sustains muscle wasting, and targeting this receptor could be a promising approach to counteract the cachectic syndrome.

Introduction: Mindful movement is a comprehensive approach that integrates various bodily, emotional and cognitive aspects into physical activity, promoting overall well-being. This study assessed the impact of a mindful movement program, known as Movimento Biologico (MB), on participants psychological well-being (PWB), positive mental health (PMH), sense of coherence (SOC), and interoceptive awareness., Methods: MB program was conducted for students attending the bachelor's degree in Kinesiology and Sport Sciences of University of Perugia over 8 weeks (from October 16 to November 27, 2022). Participants were requested to fill in four questionnaires before and after the MB program: (1) 18-item PWB scale; (2) 9-item PMH scale; (3) 13-item SOC scale; (4) 32-item scale for Multidimensional Assessment of Interoceptive Awareness (MAIA). Wilcoxon signed-rank tests were used to assess changes, with significance set at p  < 0.05., Results: Thirty-eight students (mean age 21.2, 60.5% male) participated. Several MAIA subscales, including noticing ( p  = 0.003), attention management ( p  = 0.002), emotional awareness ( p  = 0.007), self-regulation ( p  < 0.001), body listening ( p  = 0.001), and trusting ( p  = 0.001), showed significant improvements. PMH increased significantly ( p  = 0.015), and there was a significant enhancement in the autonomy subscale of PWB ( p  = 0.036). SOC and overall PWB also improved, though not significantly., Conclusion: The MB program significantly improved participants' positive mental health and interoceptive awareness. This likely resulted from better recognition and management of positive physiological sensations, a stronger link between physical sensations and emotions, enhanced confidence in one's body, and increased autonomy., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision., (Copyright © 2024 Spaccapanico Proietti, Chiavarini, Iorio, Buratta, Pocetta, Carestia, Gobbetti, Lupi, Cosenza, Sorci, Mazzeschi, Biscarini and de Waure.)