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The use of cultural sites has been profoundly altered by the recent pandemic events with relevant consequences on the cultural heritage industry. While before the CoVid-19 pandemic access to Cultural Sites used to involve a simplified form of control, in the transitional period between the pandemic and the post-pandemic, additional steps are required. The research aims to combine seemingly distant aspects: counteracting the spread of contagion and reorganising the admission processes to institutes of culture, such as museums. Based on the literature, it has been shown that the parameters determining air quality (temperature, relative humidity, concentration of pollutants, dust, CO2, etc.) influence the state of conservation of works of art, while their interaction with the spread of the epidemic has been slightly investigated. The research seeks to find innovative technological solutions to allow access and safe visits to the greatest possible number of users. A conscious design, therefore, must be put in place to allow everyone to enjoy works of art, exhibitions and shows. This is how the concept of universal design is declined here, introducing the concept of 'safe environment accessibility'. The first results of a research carried out on the microclimate and the air quality inside Tyrannicides Hall at the National Archaeological Museum of Naples (MANN) will be presented. A device called 'CapsulART' is designed to be placed at the entrance of a specific room, which acts as a filter and as a decompression chamber to lower the level of pollutants present on people's clothes and shoe soles. Through a reduction in temperature, parameters that may increase the ease of contagion (e.g. sweating) should be decreased.